Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #absentNotch_versus_truncNotch_repos |
| Phenotype | phenotype_absentNotch_versus_truncNotch.cls#absentNotch_versus_truncNotch_repos |
| Upregulated in class | absentNotch |
| GeneSet | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS |
| Enrichment Score (ES) | 0.83438617 |
| Normalized Enrichment Score (NES) | 1.6901085 |
| Nominal p-value | 0.002079002 |
| FDR q-value | 0.05887401 |
| FWER p-Value | 0.134 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | MCM4 | 2760673 5420711 | 68 | 1.651 | 0.1268 | Yes | ||
| 2 | CDK2 | 130484 2260301 4010088 5050110 | 84 | 1.554 | 0.2487 | Yes | ||
| 3 | MCM6 | 60092 540181 6510110 | 128 | 1.370 | 0.3546 | Yes | ||
| 4 | CDC7 | 4060546 4850041 | 133 | 1.359 | 0.4618 | Yes | ||
| 5 | RFC4 | 3800082 6840142 | 145 | 1.314 | 0.5650 | Yes | ||
| 6 | RFC5 | 3800452 6020091 | 236 | 1.048 | 0.6430 | Yes | ||
| 7 | HUS1 | 3440494 3800156 | 402 | 0.845 | 0.7009 | Yes | ||
| 8 | RPA3 | 5700136 | 630 | 0.672 | 0.7418 | Yes | ||
| 9 | RPA1 | 360452 | 914 | 0.539 | 0.7692 | Yes | ||
| 10 | CDC25A | 3800184 | 1320 | 0.382 | 0.7776 | Yes | ||
| 11 | ORC5L | 1940133 1940711 | 1454 | 0.347 | 0.7978 | Yes | ||
| 12 | RFC3 | 1980600 | 1527 | 0.329 | 0.8200 | Yes | ||
| 13 | CDC45L | 70537 3130114 | 1679 | 0.285 | 0.8344 | Yes | ||
| 14 | MCM3 | 5570068 | 2691 | 0.107 | 0.7885 | No | ||
| 15 | MCM7 | 3290292 5220056 | 2733 | 0.103 | 0.7944 | No | ||
| 16 | ORC2L | 1990470 6510019 | 3821 | 0.035 | 0.7387 | No | ||
| 17 | RAD9B | 2320064 | 3870 | 0.033 | 0.7387 | No | ||
| 18 | CHEK1 | 50167 1940300 | 4014 | 0.028 | 0.7333 | No | ||
| 19 | ORC4L | 4230538 5550288 | 4055 | 0.027 | 0.7332 | No | ||
| 20 | CDC25C | 2570673 4760161 6520707 | 6018 | 0.006 | 0.6282 | No | ||
| 21 | MCM10 | 4920632 | 10531 | -0.007 | 0.3860 | No | ||
| 22 | RAD1 | 4200551 | 11076 | -0.009 | 0.3575 | No | ||
| 23 | MCM2 | 5050139 | 12705 | -0.020 | 0.2715 | No | ||
| 24 | MCM5 | 2680647 | 15739 | -0.127 | 0.1184 | No | ||
| 25 | ORC1L | 2370328 6110390 | 16154 | -0.179 | 0.1103 | No | ||
| 26 | RPA2 | 2760301 5420195 | 16845 | -0.280 | 0.0953 | No |
