Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
| Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | SEQUENCE_SPECIFIC_DNA_BINDING |
| Enrichment Score (ES) | -0.7395192 |
| Normalized Enrichment Score (NES) | -1.5529935 |
| Nominal p-value | 0.0072289156 |
| FDR q-value | 0.43335596 |
| FWER p-Value | 0.953 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | HMGA1 | 6580408 | 1592 | 0.440 | -0.0520 | No | ||
| 2 | MBD4 | 7100373 | 1983 | 0.321 | -0.0484 | No | ||
| 3 | TRIM28 | 380292 | 2074 | 0.299 | -0.0303 | No | ||
| 4 | ORC5L | 1940133 1940711 | 2680 | 0.173 | -0.0496 | No | ||
| 5 | KIF2C | 6940082 | 2900 | 0.139 | -0.0508 | No | ||
| 6 | ORC3L | 3060348 | 3527 | 0.080 | -0.0784 | No | ||
| 7 | ORC2L | 1990470 6510019 | 3784 | 0.065 | -0.0872 | No | ||
| 8 | TBX3 | 2570672 | 4443 | 0.038 | -0.1197 | No | ||
| 9 | FOXD4 | 2470315 | 4716 | 0.031 | -0.1320 | No | ||
| 10 | BPTF | 940541 4540152 | 4974 | 0.026 | -0.1438 | No | ||
| 11 | GLI2 | 3060632 | 5212 | 0.022 | -0.1549 | No | ||
| 12 | TINF2 | 2360358 | 5513 | 0.019 | -0.1696 | No | ||
| 13 | NR0B1 | 6510750 | 5928 | 0.015 | -0.1907 | No | ||
| 14 | POT1 | 5340184 | 5983 | 0.015 | -0.1925 | No | ||
| 15 | TBX2 | 1990563 | 5988 | 0.015 | -0.1915 | No | ||
| 16 | TBX5 | 2900132 6370484 | 6099 | 0.014 | -0.1964 | No | ||
| 17 | NR5A2 | 1690180 6900050 | 6623 | 0.011 | -0.2237 | No | ||
| 18 | FOXD1 | 6860053 | 7059 | 0.009 | -0.2465 | No | ||
| 19 | FOXC2 | 4150041 | 7370 | 0.008 | -0.2626 | No | ||
| 20 | GCM2 | 2370041 | 7457 | 0.007 | -0.2667 | No | ||
| 21 | ORC4L | 4230538 5550288 | 7847 | 0.006 | -0.2872 | No | ||
| 22 | RORB | 6400035 | 8217 | 0.005 | -0.3067 | No | ||
| 23 | FIGLA | 4780458 | 8830 | 0.003 | -0.3395 | No | ||
| 24 | FOXF2 | 1240091 | 9092 | 0.002 | -0.3534 | No | ||
| 25 | MBD2 | 5900546 | 9145 | 0.002 | -0.3560 | No | ||
| 26 | PURA | 3870156 | 9881 | -0.000 | -0.3956 | No | ||
| 27 | SREBF1 | 4780333 | 10333 | -0.002 | -0.4198 | No | ||
| 28 | FOXC1 | 580239 | 11625 | -0.006 | -0.4889 | No | ||
| 29 | FOXL1 | 2850017 | 12650 | -0.010 | -0.5432 | No | ||
| 30 | FOXH1 | 2060180 | 12843 | -0.011 | -0.5527 | No | ||
| 31 | TBX1 | 3710133 6590121 | 13056 | -0.013 | -0.5632 | No | ||
| 32 | HMGA2 | 2940121 3390647 5130279 6400136 | 13058 | -0.013 | -0.5622 | No | ||
| 33 | TERT | 6660075 | 13081 | -0.013 | -0.5624 | No | ||
| 34 | TERF1 | 2340113 | 13358 | -0.015 | -0.5761 | No | ||
| 35 | TERF2IP | 580010 870364 2190358 | 14217 | -0.027 | -0.6203 | No | ||
| 36 | FOXO3 | 2510484 4480451 | 14837 | -0.044 | -0.6503 | No | ||
| 37 | SP1 | 6590017 | 14989 | -0.051 | -0.6545 | No | ||
| 38 | CXXC1 | 630170 3940136 | 15236 | -0.067 | -0.6626 | No | ||
| 39 | HNRPAB | 540504 | 15300 | -0.072 | -0.6605 | No | ||
| 40 | NR6A1 | 4010347 | 16354 | -0.196 | -0.7022 | No | ||
| 41 | FOXP3 | 940707 1850692 | 16393 | -0.203 | -0.6887 | No | ||
| 42 | SMG6 | 5820243 | 17338 | -0.470 | -0.7035 | Yes | ||
| 43 | LEF1 | 2470082 7100288 | 17770 | -0.695 | -0.6734 | Yes | ||
| 44 | TERF2 | 3840044 | 17909 | -0.791 | -0.6202 | Yes | ||
| 45 | SMAD3 | 6450671 | 17977 | -0.846 | -0.5590 | Yes | ||
| 46 | ZW10 | 2900735 3520687 | 18092 | -0.980 | -0.4900 | Yes | ||
| 47 | SMAD4 | 5670519 | 18156 | -1.063 | -0.4119 | Yes | ||
| 48 | ELK3 | 460377 1400762 3710497 | 18561 | -2.759 | -0.2222 | Yes | ||
| 49 | BCL6 | 940100 | 18572 | -2.937 | 0.0024 | Yes |
