Details for gene set CELLULAR_BIOSYNTHETIC

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos
Phenotype	phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos
Upregulated in class	absentNotch
GeneSet	CELLULAR_BIOSYNTHETIC_PROCESS
Enrichment Score (ES)	0.6302517
Normalized Enrichment Score (NES)	1.5788699
Nominal p-value	0.0
FDR q-value	0.27883887
FWER p-Value	0.633

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	EEF1A1	1980193 1990195 4670735	1	7.977	0.0659	Yes
2	RPL38	70040 4060138 6200601	2	7.446	0.1274	Yes
3	RPL21	110176 3610075 5700563	9	5.366	0.1714	Yes
4	PABPC4	1990170 6760270 5390138	20	4.232	0.2058	Yes
5	RPL27A	3130451 110195 6840494	72	2.999	0.2279	Yes
6	EIF2B5	430315 6900400	92	2.667	0.2489	Yes
7	RPL3L	130167	119	2.411	0.2674	Yes
8	AGPAT2	6110592	152	2.200	0.2838	Yes
9	ALAD	780576	172	2.081	0.3000	Yes
10	EIF1	5080100	223	1.814	0.3122	Yes
11	INHBB	2680092	227	1.782	0.3268	Yes
12	UMPS	2340541 4730438	258	1.657	0.3389	Yes
13	EIF4A2	1170494 1740711 2850504	297	1.542	0.3495	Yes
14	AARS	1570279 2370136	302	1.539	0.3620	Yes
15	PDZD3	630711	306	1.525	0.3745	Yes
16	GUK1	5900059	322	1.483	0.3859	Yes
17	MRPL3	1170736 5270025	343	1.454	0.3968	Yes
18	DARS	580427 3840139	376	1.382	0.4065	Yes
19	EIF2B3	3290463	448	1.256	0.4130	Yes
20	ATF4	730441 1740195	464	1.227	0.4223	Yes
21	ETF1	6770075	472	1.218	0.4320	Yes
22	RARS	380390	485	1.187	0.4412	Yes
23	EIF2B2	4290048	490	1.174	0.4507	Yes
24	PPAT	1980019	515	1.138	0.4588	Yes
25	GCH1	670364 6550358	525	1.126	0.4676	Yes
26	HPRT1	1690398 4920619 6350170	527	1.120	0.4768	Yes
27	ADM	4810121	545	1.100	0.4849	Yes
28	MIF	3710332	587	1.052	0.4914	Yes
29	COPS5	1340722 5050215	600	1.040	0.4993	Yes
30	NACA	520326 5890673	626	1.015	0.5064	Yes
31	FARSB	2030079	653	0.979	0.5130	Yes
32	EIF4B	5390563 5270577	688	0.933	0.5189	Yes
33	MRPL55	2260075	693	0.930	0.5264	Yes
34	MRPS7	4730270	720	0.907	0.5324	Yes
35	RPS3A	2470086	731	0.899	0.5393	Yes
36	EIF5	6380750	736	0.893	0.5465	Yes
37	RPS19	5860066	739	0.891	0.5538	Yes
38	HBS1L	940072 1450301 4070129	758	0.875	0.5600	Yes
39	TSTA3	1230100	812	0.833	0.5640	Yes
40	RPL30	4810369	890	0.783	0.5663	Yes
41	BCAT1	3290128 4050408	955	0.747	0.5690	Yes
42	SLC25A10	1400609	977	0.733	0.5739	Yes
43	SCYE1	4730736	997	0.718	0.5788	Yes
44	COX15	2360402	1015	0.705	0.5837	Yes
45	RRBP1	2260477 5050440	1055	0.680	0.5872	Yes
46	ABCF1	2630707 2760273 3520725	1097	0.657	0.5904	Yes
47	PAICS	610142	1102	0.654	0.5956	Yes
48	MRPS24	5340022	1213	0.598	0.5945	Yes
49	COQ7	3190632	1226	0.593	0.5987	Yes
50	CTPS	70451 1740132	1308	0.554	0.5989	Yes
51	RPL22	4070070	1319	0.549	0.6029	Yes
52	SOD1	5890070	1355	0.530	0.6054	Yes
53	EIF4G3	670707	1356	0.529	0.6098	Yes
54	EIF4G2	3800575 6860184	1379	0.522	0.6129	Yes
55	PYCR1	6180670	1515	0.469	0.6094	Yes
56	EIF4A3	3440538	1606	0.435	0.6081	Yes
57	HSPB1	6760435	1630	0.427	0.6104	Yes
58	EIF2B1	4610082 7040242	1642	0.423	0.6133	Yes
59	RPL31	5690685	1649	0.420	0.6164	Yes
60	DHPS	5340735	1671	0.413	0.6187	Yes
61	GAMT	6980301	1694	0.407	0.6208	Yes
62	KARS	6520575	1731	0.399	0.6222	Yes
63	RPL29	1240075	1768	0.387	0.6234	Yes
64	GMPS	460670	1804	0.373	0.6246	Yes
65	MRPL51	540670 1580026	1831	0.365	0.6262	Yes
66	RPL23A	1450403	1881	0.352	0.6264	Yes
67	COX10	3140136	1885	0.351	0.6292	Yes
68	MRPL10	4120484	1930	0.336	0.6295	Yes
69	RPL14	5080471	2026	0.312	0.6269	Yes
70	ARPP-19	5700025	2044	0.307	0.6286	Yes
71	ACN9	6660180	2119	0.284	0.6269	Yes
72	TUFM	3290685	2151	0.278	0.6275	Yes
73	COASY	6220707	2152	0.278	0.6298	Yes
74	PAIP1	3870576	2185	0.268	0.6303	Yes
75	IL10	2340685 2640541 2850403 6590286	2268	0.251	0.6279	No
76	ALAS1	6400440	2324	0.238	0.6268	No
77	RPS3	1570017 2370170	2339	0.234	0.6280	No
78	MRPL52	1170204	2384	0.225	0.6275	No
79	RPL5	840095	2401	0.222	0.6284	No
80	PNPLA3	5050551	2699	0.168	0.6136	No
81	PET112L	780142 2260435 4200739	2786	0.156	0.6102	No
82	EEF2K	3800673	2916	0.137	0.6044	No
83	FECH	2810605 3120088 4920411	2926	0.135	0.6050	No
84	MOCS2	2940497	2964	0.132	0.6041	No
85	YARS	70739	3021	0.126	0.6020	No
86	BACE2	4060170 5690100 6220133	3031	0.125	0.6026	No
87	RPL26	5220592	3106	0.116	0.5995	No
88	RPS2	1340647	3130	0.114	0.5992	No
89	EIF2AK1	2470301	3150	0.112	0.5991	No
90	PLOD1	6040427	3198	0.108	0.5974	No
91	DDX25	5910121	3210	0.107	0.5977	No
92	FARS2	5340575	3236	0.103	0.5972	No
93	RPL24	3870273	3375	0.092	0.5905	No
94	RPL4	2940014 5420324	3429	0.087	0.5883	No
95	PTGES3	2190440 2680524	3434	0.087	0.5888	No
96	RPL3	2060138	3471	0.084	0.5875	No
97	RPL18A	4570619	3479	0.083	0.5878	No
98	RPL7	3840647	3499	0.082	0.5875	No
99	AK5	6290348	3558	0.078	0.5850	No
100	SPR	6840170	3590	0.077	0.5839	No
101	RPL7A	5420458	3699	0.070	0.5786	No
102	TLR4	1690167 2650369 3850333	3773	0.065	0.5752	No
103	DGAT2	5130685	3812	0.063	0.5736	No
104	SFTPD	6510181	3920	0.057	0.5683	No
105	ADCY7	6290520 7560739	3945	0.056	0.5674	No
106	EXT1	4540603	4032	0.052	0.5632	No
107	CHST7	2760066	4073	0.051	0.5614	No
108	RPL8	20296	4086	0.050	0.5612	No
109	PDSS1	3830170	4254	0.044	0.5524	No
110	NDST1	1500427 5340121	4271	0.043	0.5519	No
111	SARS2	3190390	4291	0.043	0.5512	No
112	NR5A1	70707	4389	0.040	0.5463	No
113	METAP1	3520632	4606	0.034	0.5348	No
114	PTGS1	730193 1780273 6450195	4702	0.031	0.5299	No
115	RPL6	6040735	4715	0.031	0.5295	No
116	RPS17	2360528	4804	0.029	0.5249	No
117	TLR6	510102 3390148	5079	0.025	0.5102	No
118	APOA2	6510364 6860411	5202	0.023	0.5037	No
119	DHRS9	3710711 4760142	5276	0.022	0.4999	No
120	BCL3	3990440	5383	0.020	0.4943	No
121	GCLM	4230270	5386	0.020	0.4944	No
122	ELA2	1570452 5270129	5418	0.020	0.4929	No
123	HSD3B7	1410129	5419	0.020	0.4930	No
124	PTGDS	3610519	5440	0.020	0.4921	No
125	PPARGC1A	4670040	5467	0.019	0.4909	No
126	DEFB103A	50014	5544	0.019	0.4869	No
127	BRCA1	4780669	5916	0.015	0.4668	No
128	GLMN	5290563 5890239	5993	0.015	0.4628	No
129	HSP90AA1	4560041 5220133 2120722	6024	0.015	0.4613	No
130	IL4	6020537	6051	0.014	0.4600	No
131	AKR1D1	6770026	6124	0.014	0.4562	No
132	INHA	6100102	6190	0.013	0.4527	No
133	TLR7	3140300	6273	0.013	0.4484	No
134	RPS10	4560673	6330	0.013	0.4454	No
135	ALDH9A1	4810047	6447	0.012	0.4392	No
136	CDO1	2480279	6580	0.011	0.4321	No
137	CYP7B1	1190309	6687	0.011	0.4264	No
138	RPS6KB2	6220600	7242	0.008	0.3963	No
139	IL12B	460008	7250	0.008	0.3960	No
140	GPR143	4780671	7305	0.008	0.3931	No
141	IL9	3440338	7568	0.007	0.3789	No
142	TNFRSF8	870136 4810446	7738	0.006	0.3697	No
143	HSD11B2	5900053	7739	0.006	0.3698	No
144	AKT1	5290746	7797	0.006	0.3667	No
145	RPL39	2370446	7885	0.006	0.3620	No
146	CYP27B1	5270114 5360010	7986	0.005	0.3566	No
147	TYR	5690139	7994	0.005	0.3563	No
148	COQ3	3850324	8204	0.005	0.3450	No
149	NQO1	3450136 6840121	8380	0.004	0.3355	No
150	SAMD4A	1170717	8403	0.004	0.3343	No
151	TLR9	670093 670706	8439	0.004	0.3324	No
152	UGDH	4730400	8541	0.004	0.3269	No
153	GLA	4610364	8755	0.003	0.3154	No
154	CHST8	1940050	8801	0.003	0.3129	No
155	CHST9	4560092	8913	0.003	0.3069	No
156	UCN2	4590372	9031	0.002	0.3006	No
157	BBOX1	2030538 2370452	9056	0.002	0.2993	No
158	TLR8	1240092	9157	0.002	0.2938	No
159	DCT	1090347 3840494	9394	0.001	0.2810	No
160	TLR3	6760451	9563	0.001	0.2719	No
161	IL6	380133	9755	0.000	0.2614	No
162	ABCA1	6290156	9882	-0.000	0.2546	No
163	IL27	1990324	9885	-0.000	0.2545	No
164	BMP6	2100128	10136	-0.001	0.2409	No
165	GHSR	1980465 7050521	10218	-0.001	0.2365	No
166	ADK	380338 520180 5270524	10256	-0.001	0.2345	No
167	MTIF2	2260270	10571	-0.002	0.2174	No
168	EIF2AK4	4810091	10583	-0.002	0.2168	No
169	GATM	380671	10744	-0.003	0.2081	No
170	EIF2C1	6900551	10857	-0.003	0.2020	No
171	TSC1	1850672	10975	-0.003	0.1957	No
172	YBX2	3520441	11011	-0.004	0.1938	No
173	DMD	1740041 3990332	11250	-0.004	0.1809	No
174	MAT2B	1690139 2510706	11381	-0.005	0.1738	No
175	TGFB2	4920292	11752	-0.006	0.1537	No
176	CHST3	2370131	12058	-0.007	0.1372	No
177	GCK	2370273	12125	-0.008	0.1337	No
178	TLR1	1410524	12168	-0.008	0.1314	No
179	PFKFB1	2370128	12202	-0.008	0.1297	No
180	GLCE	4850040	12436	-0.009	0.1171	No
181	PEX7	2970180 6660270	12760	-0.011	0.0996	No
182	CYP11B2	5340129	12768	-0.011	0.0993	No
183	PAH	3800309	12875	-0.012	0.0936	No
184	SLC5A7	4760091	13076	-0.013	0.0828	No
185	ALDH18A1	2340601	13119	-0.013	0.0806	No
186	EREG	50519 4920129	13196	-0.014	0.0766	No
187	PMM2	670673 2570044 2690093 4540068 6450056	13313	-0.015	0.0704	No
188	GCLC	2810731	13399	-0.015	0.0659	No
189	HSP90AB1	3170358 5390102 6040093	13470	-0.016	0.0622	No
190	GRM8	4780082	13492	-0.016	0.0612	No
191	RPL18	6380181 3870195	13681	-0.018	0.0511	No
192	CPOX	1940452 2120184	13707	-0.019	0.0499	No
193	DAZL	4050082	13735	-0.019	0.0486	No
194	RPL41	6940112	13805	-0.020	0.0450	No
195	CHST11	6760546	13822	-0.020	0.0443	No
196	IL17F	670577	13842	-0.021	0.0435	No
197	GHRL	2360619 6760438	13902	-0.021	0.0404	No
198	PLCE1	4780685	13911	-0.022	0.0402	No
199	RPL37	3170494 3870750 4280494	13985	-0.023	0.0364	No
200	EGFR	4920138 6480521	14057	-0.024	0.0327	No
201	HSD3B1	3060672	14564	-0.034	0.0054	No
202	EBI3	5340300	14655	-0.036	0.0008	No
203	BOLL	6100743	14656	-0.037	0.0011	No
204	FURIN	4120168	14787	-0.042	-0.0056	No
205	RPL28	6900136	14904	-0.047	-0.0115	No
206	CYP11A1	3450037	14930	-0.048	-0.0125	No
207	FADS2	630253	14993	-0.052	-0.0155	No
208	CYP39A1	1170020 5220722	15020	-0.053	-0.0164	No
209	CHST12	2030438	15065	-0.056	-0.0184	No
210	ADORA2A	1990687	15105	-0.058	-0.0200	No
211	DPH1	1340551 2070747 6130452	15106	-0.058	-0.0195	No
212	RPL13	580280	15154	-0.061	-0.0216	No
213	HS3ST3B1	380040	15209	-0.066	-0.0240	No
214	RPL35	6940070	15237	-0.067	-0.0249	No
215	PRG3	6220020	15321	-0.073	-0.0288	No
216	APBB1	2690338	15479	-0.087	-0.0366	No
217	HPGD	6770192	15510	-0.089	-0.0375	No
218	UPF1	430164 1190750	15512	-0.090	-0.0369	No
219	RPS5	580093	15580	-0.099	-0.0397	No
220	RPS11	4120403	15606	-0.101	-0.0402	No
221	HRSP12	610136 2510133 4280561 2760047	15695	-0.110	-0.0441	No
222	EIF2B4	5270082	15735	-0.114	-0.0453	No
223	PPOX	2640678 3850102	15867	-0.128	-0.0514	No
224	FADS1	5270537	15875	-0.129	-0.0507	No
225	RPL11	3780435	16011	-0.144	-0.0568	No
226	RPL19	5550592	16174	-0.168	-0.0643	No
227	EIF4H	610324	16196	-0.171	-0.0640	No
228	PAIP2	4210441	16225	-0.174	-0.0641	No
229	RPL15	6290731	16306	-0.187	-0.0669	No
230	RPS27	5270242	16337	-0.192	-0.0670	No
231	DDAH2	4480551	16392	-0.203	-0.0682	No
232	FOXP3	940707 1850692	16393	-0.203	-0.0665	No
233	DEGS1	5910021	16457	-0.215	-0.0682	No
234	MTRF1	1660022 2340605	16666	-0.263	-0.0774	No
235	IRF4	610133	16775	-0.287	-0.0809	No
236	MRPL23	4070142	16797	-0.292	-0.0796	No
237	NDUFA13	6220021	16871	-0.312	-0.0810	No
238	GMDS	1050519	16874	-0.313	-0.0785	No
239	TSPO	110692 3390452	16981	-0.343	-0.0815	No
240	AGPAT1	610056	17014	-0.351	-0.0803	No
241	LTA4H	520020 5670673	17103	-0.385	-0.0819	No
242	OAZ1	110181	17149	-0.400	-0.0811	No
243	EIF5A	1500059 5290022 6370026	17308	-0.457	-0.0859	No
244	MAST2	6200348	17415	-0.502	-0.0875	No
245	PTS	1500270	17495	-0.536	-0.0874	No
246	UROS	3360139 4120133	17533	-0.553	-0.0848	No
247	AP3D1	4540138	17614	-0.600	-0.0842	No
248	EIF2AK3	4280161	17674	-0.640	-0.0821	No
249	WARS	2570717 3290139	17753	-0.685	-0.0807	No
250	BCL10	2360397	17788	-0.705	-0.0768	No
251	NFE2L1	6130053	17794	-0.709	-0.0712	No
252	SPN	3520338 3870671	18046	-0.934	-0.0771	No
253	TYMS	940450 1940068 3710008 5570546	18068	-0.958	-0.0704	No
254	HS6ST1	4760373	18323	-1.377	-0.0728	No
255	CD28	1400739 4210093	18406	-1.672	-0.0635	No
256	ALAS2	6550176	18489	-2.042	-0.0510	No
257	LTB	3990672	18557	-2.728	-0.0322	No
258	TNIP1	2510279 5900041 6510435	18608	-4.273	0.0004	No