Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
Upregulated in class | absentNotch |
GeneSet | V$USF_C |
Enrichment Score (ES) | 0.60390174 |
Normalized Enrichment Score (NES) | 1.4621062 |
Nominal p-value | 0.0061255745 |
FDR q-value | 0.4668909 |
FWER p-Value | 0.982 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PABPC1 | 2650180 2690253 6020632 1990270 | 3 | 6.314 | 0.0830 | Yes | ||
2 | TIMM10 | 610070 1450019 | 12 | 4.552 | 0.1426 | Yes | ||
3 | PABPC4 | 1990170 6760270 5390138 | 20 | 4.232 | 0.1980 | Yes | ||
4 | HMOX1 | 1740687 | 30 | 3.784 | 0.2473 | Yes | ||
5 | AKAP12 | 1450739 | 186 | 2.035 | 0.2657 | Yes | ||
6 | SH3KBP1 | 670102 2850458 7000309 | 219 | 1.839 | 0.2882 | Yes | ||
7 | PFDN2 | 4230156 | 382 | 1.369 | 0.2975 | Yes | ||
8 | FBL | 5130020 | 398 | 1.351 | 0.3145 | Yes | ||
9 | LYAR | 7000402 | 441 | 1.275 | 0.3290 | Yes | ||
10 | IPO4 | 5050619 | 451 | 1.250 | 0.3450 | Yes | ||
11 | PPAT | 1980019 | 515 | 1.138 | 0.3566 | Yes | ||
12 | NUDC | 4780025 | 524 | 1.127 | 0.3710 | Yes | ||
13 | NR1D1 | 2360471 770746 6590204 | 543 | 1.102 | 0.3845 | Yes | ||
14 | FKBP11 | 3170575 | 552 | 1.094 | 0.3985 | Yes | ||
15 | IVNS1ABP | 4760601 6520113 | 615 | 1.022 | 0.4086 | Yes | ||
16 | EXOSC5 | 3370671 | 659 | 0.963 | 0.4190 | Yes | ||
17 | EIF4B | 5390563 5270577 | 688 | 0.933 | 0.4297 | Yes | ||
18 | RPS19 | 5860066 | 739 | 0.891 | 0.4388 | Yes | ||
19 | GPD1 | 2480095 | 747 | 0.885 | 0.4501 | Yes | ||
20 | EIF2C2 | 770451 | 778 | 0.857 | 0.4597 | Yes | ||
21 | G6PC3 | 1580487 5390253 | 789 | 0.849 | 0.4704 | Yes | ||
22 | PA2G4 | 2030463 | 823 | 0.827 | 0.4795 | Yes | ||
23 | ALDH3B1 | 4210010 6940403 | 834 | 0.821 | 0.4897 | Yes | ||
24 | HSPE1 | 3170438 | 845 | 0.815 | 0.4999 | Yes | ||
25 | ABCB6 | 6350138 | 943 | 0.753 | 0.5046 | Yes | ||
26 | HYAL2 | 1500152 | 952 | 0.749 | 0.5140 | Yes | ||
27 | SDC1 | 3440471 6350408 | 962 | 0.741 | 0.5233 | Yes | ||
28 | HSPH1 | 1690017 | 981 | 0.731 | 0.5320 | Yes | ||
29 | EXOSC2 | 6900471 | 1032 | 0.694 | 0.5384 | Yes | ||
30 | ENO3 | 5270136 | 1086 | 0.660 | 0.5442 | Yes | ||
31 | PAICS | 610142 | 1102 | 0.654 | 0.5520 | Yes | ||
32 | BHLHB2 | 7040603 | 1201 | 0.607 | 0.5547 | Yes | ||
33 | HERPUD1 | 7100440 | 1202 | 0.607 | 0.5627 | Yes | ||
34 | PER1 | 3290315 | 1217 | 0.596 | 0.5698 | Yes | ||
35 | STMN1 | 1990717 | 1289 | 0.561 | 0.5733 | Yes | ||
36 | SUCLG2 | 5340397 5700270 | 1313 | 0.552 | 0.5794 | Yes | ||
37 | RPL22 | 4070070 | 1319 | 0.549 | 0.5863 | Yes | ||
38 | PSMB3 | 4280594 | 1463 | 0.488 | 0.5850 | Yes | ||
39 | EFNB1 | 2970433 | 1553 | 0.454 | 0.5861 | Yes | ||
40 | OPRS1 | 6130128 6290717 | 1656 | 0.418 | 0.5861 | Yes | ||
41 | POLR3E | 380152 | 1681 | 0.410 | 0.5902 | Yes | ||
42 | GTF2H1 | 2570746 2650148 | 1763 | 0.390 | 0.5910 | Yes | ||
43 | MYOHD1 | 1410520 | 1790 | 0.380 | 0.5946 | Yes | ||
44 | POLR2H | 5890242 | 1899 | 0.346 | 0.5933 | Yes | ||
45 | SRP72 | 3990427 | 1920 | 0.340 | 0.5967 | Yes | ||
46 | RHEBL1 | 2810576 | 1959 | 0.327 | 0.5989 | Yes | ||
47 | HMGN2 | 3140091 | 1962 | 0.326 | 0.6031 | Yes | ||
48 | MORF4L2 | 6450133 | 2024 | 0.312 | 0.6039 | Yes | ||
49 | EIF4G1 | 4070446 | 2101 | 0.290 | 0.6036 | No | ||
50 | FHOD1 | 2680279 | 2286 | 0.246 | 0.5969 | No | ||
51 | EEF1E1 | 4540711 | 2389 | 0.225 | 0.5943 | No | ||
52 | H3F3A | 2900086 | 2485 | 0.208 | 0.5919 | No | ||
53 | TNFRSF21 | 6380100 | 2502 | 0.202 | 0.5937 | No | ||
54 | UBXD3 | 5050193 | 2750 | 0.161 | 0.5824 | No | ||
55 | PPARGC1B | 3290114 | 2856 | 0.146 | 0.5786 | No | ||
56 | PTMA | 5570148 | 2997 | 0.128 | 0.5727 | No | ||
57 | PSEN2 | 130382 | 3230 | 0.104 | 0.5615 | No | ||
58 | CACNA1D | 1740315 4730731 | 3233 | 0.103 | 0.5627 | No | ||
59 | FARP1 | 5290102 7100341 | 3243 | 0.103 | 0.5636 | No | ||
60 | B4GALT2 | 780037 | 3257 | 0.101 | 0.5642 | No | ||
61 | CDC14A | 4050132 | 3274 | 0.100 | 0.5647 | No | ||
62 | CTSF | 6100021 | 3285 | 0.099 | 0.5654 | No | ||
63 | CAMK4 | 1690091 | 3297 | 0.098 | 0.5661 | No | ||
64 | AVP | 2100113 | 3308 | 0.097 | 0.5669 | No | ||
65 | GPX1 | 4150093 | 3336 | 0.095 | 0.5667 | No | ||
66 | MYST3 | 5270500 | 3341 | 0.094 | 0.5677 | No | ||
67 | MPP3 | 1400056 4480411 6770168 | 3465 | 0.084 | 0.5621 | No | ||
68 | SLC39A7 | 5570131 | 3559 | 0.078 | 0.5581 | No | ||
69 | RPL13A | 2680519 5700142 | 3580 | 0.077 | 0.5580 | No | ||
70 | LTBR | 2450341 | 3790 | 0.064 | 0.5475 | No | ||
71 | AMPD2 | 630093 1170070 | 3791 | 0.064 | 0.5484 | No | ||
72 | SYT3 | 6380017 | 3804 | 0.063 | 0.5486 | No | ||
73 | CNNM1 | 2190433 | 3911 | 0.058 | 0.5436 | No | ||
74 | SIRT1 | 1190731 | 4282 | 0.043 | 0.5241 | No | ||
75 | XRN2 | 130603 1230113 4230309 | 4509 | 0.036 | 0.5123 | No | ||
76 | ADCY3 | 2350347 3440242 | 4516 | 0.036 | 0.5124 | No | ||
77 | NLN | 1450576 5870575 | 4550 | 0.035 | 0.5111 | No | ||
78 | HOXA3 | 3610632 6020358 | 4725 | 0.031 | 0.5021 | No | ||
79 | TIAL1 | 4150048 6510605 | 4920 | 0.027 | 0.4919 | No | ||
80 | ETV1 | 70735 2940603 5080463 | 5007 | 0.026 | 0.4876 | No | ||
81 | SLC26A2 | 2360278 | 5053 | 0.025 | 0.4855 | No | ||
82 | ARRDC3 | 4610390 | 5195 | 0.023 | 0.4781 | No | ||
83 | SC5DL | 6650390 | 5326 | 0.021 | 0.4713 | No | ||
84 | COL2A1 | 460446 3940500 | 5364 | 0.021 | 0.4696 | No | ||
85 | SEMA7A | 2630239 5050593 | 5435 | 0.020 | 0.4661 | No | ||
86 | NXPH1 | 3870546 | 5490 | 0.019 | 0.4634 | No | ||
87 | DRD1 | 430025 | 5550 | 0.019 | 0.4604 | No | ||
88 | SOCS5 | 3830398 7100093 | 5972 | 0.015 | 0.4378 | No | ||
89 | NKX2-3 | 1990736 6940088 | 6032 | 0.015 | 0.4348 | No | ||
90 | GPRC5C | 1580372 | 6216 | 0.013 | 0.4250 | No | ||
91 | ADAMTS17 | 6510739 | 6278 | 0.013 | 0.4219 | No | ||
92 | POGK | 5290315 | 6284 | 0.013 | 0.4218 | No | ||
93 | CGN | 5890139 6370167 6400537 | 6781 | 0.010 | 0.3950 | No | ||
94 | SLC12A5 | 1980692 | 6881 | 0.009 | 0.3897 | No | ||
95 | SYT6 | 2510280 3850128 4540064 | 6997 | 0.009 | 0.3836 | No | ||
96 | LIN28 | 6590672 | 7157 | 0.008 | 0.3751 | No | ||
97 | DNMT3A | 4050068 4810717 | 7337 | 0.008 | 0.3655 | No | ||
98 | RUNX2 | 1400193 4230215 | 7615 | 0.007 | 0.3506 | No | ||
99 | TBX4 | 3060008 | 7671 | 0.006 | 0.3477 | No | ||
100 | WEE1 | 3390070 | 7696 | 0.006 | 0.3464 | No | ||
101 | PRKCE | 5700053 | 7983 | 0.005 | 0.3310 | No | ||
102 | DNAJB9 | 460114 | 8178 | 0.005 | 0.3205 | No | ||
103 | LAP3 | 2570064 | 8297 | 0.004 | 0.3142 | No | ||
104 | NPTX1 | 3710736 | 8394 | 0.004 | 0.3090 | No | ||
105 | PLA2G4A | 6380364 | 8462 | 0.004 | 0.3054 | No | ||
106 | SNX5 | 1570021 6860609 | 8488 | 0.004 | 0.3041 | No | ||
107 | SLC6A15 | 5290176 6040017 | 8575 | 0.004 | 0.2995 | No | ||
108 | GRIN2A | 6550538 | 8598 | 0.003 | 0.2984 | No | ||
109 | BMP2K | 60541 5570504 | 8691 | 0.003 | 0.2934 | No | ||
110 | HOXC12 | 5270411 | 8967 | 0.002 | 0.2785 | No | ||
111 | FADS3 | 3120079 | 9008 | 0.002 | 0.2764 | No | ||
112 | NPM1 | 4730427 | 9338 | 0.001 | 0.2586 | No | ||
113 | HS3ST3A1 | 2230497 | 9488 | 0.001 | 0.2505 | No | ||
114 | MTHFD1 | 5900398 6520427 | 9650 | 0.000 | 0.2418 | No | ||
115 | FLT3 | 2640487 | 9828 | -0.000 | 0.2321 | No | ||
116 | ELOVL4 | 5220333 | 9879 | -0.000 | 0.2294 | No | ||
117 | ABCA1 | 6290156 | 9882 | -0.000 | 0.2293 | No | ||
118 | HPCA | 6860010 | 10122 | -0.001 | 0.2164 | No | ||
119 | TIMM9 | 2450484 | 10264 | -0.001 | 0.2087 | No | ||
120 | SET | 6650286 | 10417 | -0.002 | 0.2005 | No | ||
121 | ARX | 6900504 | 10474 | -0.002 | 0.1975 | No | ||
122 | PAX6 | 1190025 | 10550 | -0.002 | 0.1935 | No | ||
123 | SATB2 | 2470181 | 10578 | -0.002 | 0.1920 | No | ||
124 | TLL1 | 2680315 | 10917 | -0.003 | 0.1737 | No | ||
125 | BMP4 | 380113 | 11085 | -0.004 | 0.1647 | No | ||
126 | CHRM1 | 4280619 | 11231 | -0.004 | 0.1569 | No | ||
127 | FGF14 | 2630390 3520075 6770048 | 11478 | -0.005 | 0.1436 | No | ||
128 | PIGW | 4810072 | 11507 | -0.005 | 0.1422 | No | ||
129 | LHX9 | 2350112 | 11515 | -0.005 | 0.1419 | No | ||
130 | SNCAIP | 4010551 | 11782 | -0.006 | 0.1275 | No | ||
131 | FGF11 | 840292 | 11845 | -0.006 | 0.1242 | No | ||
132 | KIAA0427 | 1690435 | 12337 | -0.009 | 0.0977 | No | ||
133 | HOXC13 | 4070722 | 12441 | -0.009 | 0.0923 | No | ||
134 | EIF3S1 | 6130368 6770044 | 12499 | -0.009 | 0.0893 | No | ||
135 | SCFD2 | 2480504 | 12715 | -0.011 | 0.0778 | No | ||
136 | MAX | 5220021 | 13089 | -0.013 | 0.0577 | No | ||
137 | HHIP | 6940438 | 13190 | -0.014 | 0.0524 | No | ||
138 | SLC31A2 | 1450577 | 13220 | -0.014 | 0.0511 | No | ||
139 | GRK6 | 1500053 | 13347 | -0.015 | 0.0444 | No | ||
140 | RUSC1 | 6450093 6980575 | 13381 | -0.015 | 0.0428 | No | ||
141 | TDRD1 | 4230301 6110750 | 13453 | -0.016 | 0.0392 | No | ||
142 | SGTB | 460170 | 13460 | -0.016 | 0.0391 | No | ||
143 | ENPP6 | 110524 580563 | 13651 | -0.018 | 0.0290 | No | ||
144 | DAZL | 4050082 | 13735 | -0.019 | 0.0247 | No | ||
145 | CHST11 | 6760546 | 13822 | -0.020 | 0.0203 | No | ||
146 | ETV4 | 2450605 | 14141 | -0.025 | 0.0034 | No | ||
147 | HPCAL4 | 2600484 | 14159 | -0.025 | 0.0028 | No | ||
148 | LRP8 | 3610746 5360035 | 14178 | -0.026 | 0.0022 | No | ||
149 | MCM8 | 6130743 | 14235 | -0.027 | -0.0005 | No | ||
150 | GTF2A1 | 4120138 4920524 5390110 1230397 | 14292 | -0.028 | -0.0032 | No | ||
151 | GNA13 | 4590102 | 14479 | -0.032 | -0.0128 | No | ||
152 | RXRB | 1780040 5340438 | 14746 | -0.040 | -0.0267 | No | ||
153 | CNOT4 | 2320242 6760706 | 14751 | -0.040 | -0.0264 | No | ||
154 | HOXA4 | 940152 | 15131 | -0.060 | -0.0462 | No | ||
155 | ARF6 | 3520026 | 15180 | -0.063 | -0.0480 | No | ||
156 | EIF4E | 1580403 70133 6380215 | 15251 | -0.069 | -0.0509 | No | ||
157 | DAZAP1 | 5890563 | 15456 | -0.085 | -0.0608 | No | ||
158 | MNT | 4920575 | 15554 | -0.096 | -0.0648 | No | ||
159 | ACVR2B | 1660546 | 15583 | -0.099 | -0.0650 | No | ||
160 | IPO13 | 3870088 | 15655 | -0.106 | -0.0675 | No | ||
161 | BCKDHA | 50189 | 15742 | -0.114 | -0.0706 | No | ||
162 | CRMP1 | 4810014 | 15786 | -0.119 | -0.0714 | No | ||
163 | PFN1 | 6130132 | 15921 | -0.133 | -0.0769 | No | ||
164 | USP2 | 1190292 1240253 4850035 | 16083 | -0.156 | -0.0836 | No | ||
165 | CLCN2 | 1940021 | 16149 | -0.164 | -0.0850 | No | ||
166 | RPL19 | 5550592 | 16174 | -0.168 | -0.0841 | No | ||
167 | HSPA4 | 1050170 3450309 | 16275 | -0.182 | -0.0871 | No | ||
168 | UBE1 | 4150139 7050463 | 16334 | -0.191 | -0.0877 | No | ||
169 | SLC20A1 | 6420014 | 16362 | -0.197 | -0.0866 | No | ||
170 | MAT2A | 4070026 4730079 6020280 | 16466 | -0.218 | -0.0893 | No | ||
171 | ANXA6 | 2190014 | 16582 | -0.244 | -0.0923 | No | ||
172 | PDK2 | 2690017 | 16623 | -0.253 | -0.0912 | No | ||
173 | CENTB5 | 5690128 | 17229 | -0.425 | -0.1184 | No | ||
174 | BCL9L | 6940053 | 17235 | -0.427 | -0.1130 | No | ||
175 | FCHSD2 | 5720092 | 17265 | -0.438 | -0.1088 | No | ||
176 | EIF5A | 1500059 5290022 6370026 | 17308 | -0.457 | -0.1051 | No | ||
177 | DIABLO | 2360170 | 17469 | -0.528 | -0.1068 | No | ||
178 | MXD4 | 4810113 | 17661 | -0.632 | -0.1088 | No | ||
179 | BCAS3 | 4050647 | 17690 | -0.653 | -0.1018 | No | ||
180 | GABARAP | 1450286 | 17808 | -0.719 | -0.0986 | No | ||
181 | WBP2 | 3170128 | 18054 | -0.942 | -0.0995 | No | ||
182 | HSPBAP1 | 4060022 | 18327 | -1.387 | -0.0960 | No | ||
183 | RORC | 1740121 | 18341 | -1.439 | -0.0777 | No | ||
184 | PPP1R9B | 3130619 | 18381 | -1.573 | -0.0591 | No | ||
185 | TEF | 1050050 3120397 4060487 | 18538 | -2.509 | -0.0345 | No | ||
186 | BCL6 | 940100 | 18572 | -2.937 | 0.0024 | No |