Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
Upregulated in class | absentNotch |
GeneSet | V$USF_02 |
Enrichment Score (ES) | 0.5472579 |
Normalized Enrichment Score (NES) | 1.3170732 |
Nominal p-value | 0.031626508 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PABPC1 | 2650180 2690253 6020632 1990270 | 3 | 6.314 | 0.0957 | Yes | ||
2 | HNRPA1 | 4670398 5050687 | 71 | 2.999 | 0.1375 | Yes | ||
3 | SNX8 | 3450315 | 78 | 2.947 | 0.1819 | Yes | ||
4 | BAX | 3830008 | 131 | 2.296 | 0.2139 | Yes | ||
5 | CDKN2C | 5050750 5130148 | 158 | 2.149 | 0.2452 | Yes | ||
6 | GRN | 4050239 | 163 | 2.113 | 0.2770 | Yes | ||
7 | AKAP12 | 1450739 | 186 | 2.035 | 0.3067 | Yes | ||
8 | UBE4B | 780008 3610154 | 235 | 1.731 | 0.3304 | Yes | ||
9 | UMPS | 2340541 4730438 | 258 | 1.657 | 0.3543 | Yes | ||
10 | PFDN2 | 4230156 | 382 | 1.369 | 0.3684 | Yes | ||
11 | ATF4 | 730441 1740195 | 464 | 1.227 | 0.3826 | Yes | ||
12 | AATF | 5220575 | 518 | 1.134 | 0.3970 | Yes | ||
13 | NUDC | 4780025 | 524 | 1.127 | 0.4138 | Yes | ||
14 | DDX3X | 2190020 | 528 | 1.119 | 0.4306 | Yes | ||
15 | GPR65 | 3120551 | 594 | 1.045 | 0.4430 | Yes | ||
16 | TIMM8A | 110279 | 616 | 1.021 | 0.4573 | Yes | ||
17 | CCAR1 | 3190092 | 682 | 0.940 | 0.4680 | Yes | ||
18 | EIF4B | 5390563 5270577 | 688 | 0.933 | 0.4819 | Yes | ||
19 | ASNA1 | 3830041 | 882 | 0.787 | 0.4834 | Yes | ||
20 | VPS16 | 430064 3390041 6860301 | 885 | 0.786 | 0.4952 | Yes | ||
21 | UTP14A | 6590048 | 959 | 0.744 | 0.5026 | Yes | ||
22 | RFC1 | 1190673 | 960 | 0.743 | 0.5138 | Yes | ||
23 | CD164 | 3830594 | 1103 | 0.653 | 0.5160 | Yes | ||
24 | CLN3 | 780368 | 1147 | 0.635 | 0.5234 | Yes | ||
25 | PER1 | 3290315 | 1217 | 0.596 | 0.5287 | Yes | ||
26 | PTGES2 | 4210097 | 1253 | 0.577 | 0.5355 | Yes | ||
27 | COMMD3 | 2510259 | 1377 | 0.523 | 0.5368 | Yes | ||
28 | MRPL27 | 2060131 | 1449 | 0.496 | 0.5405 | Yes | ||
29 | SUPV3L1 | 1170072 | 1565 | 0.449 | 0.5410 | Yes | ||
30 | OPRS1 | 6130128 6290717 | 1656 | 0.418 | 0.5425 | Yes | ||
31 | GTF2H1 | 2570746 2650148 | 1763 | 0.390 | 0.5427 | Yes | ||
32 | PRPS1 | 6350129 | 1900 | 0.346 | 0.5405 | Yes | ||
33 | RHEBL1 | 2810576 | 1959 | 0.327 | 0.5424 | Yes | ||
34 | ATP6V1C1 | 2690324 5220528 | 2023 | 0.312 | 0.5437 | Yes | ||
35 | ARPP-19 | 5700025 | 2044 | 0.307 | 0.5473 | Yes | ||
36 | TOPORS | 4060592 | 2376 | 0.227 | 0.5328 | No | ||
37 | TAF6L | 1850056 | 2630 | 0.179 | 0.5218 | No | ||
38 | UBXD3 | 5050193 | 2750 | 0.161 | 0.5177 | No | ||
39 | ATP6V1A | 6590242 | 2765 | 0.159 | 0.5194 | No | ||
40 | MCAM | 5130270 6620577 | 2819 | 0.152 | 0.5188 | No | ||
41 | H2AFY | 4730750 | 2921 | 0.136 | 0.5154 | No | ||
42 | PTMA | 5570148 | 2997 | 0.128 | 0.5133 | No | ||
43 | STC2 | 4920601 | 2999 | 0.128 | 0.5152 | No | ||
44 | RPS2 | 1340647 | 3130 | 0.114 | 0.5099 | No | ||
45 | RAI14 | 770288 1660075 | 3225 | 0.105 | 0.5064 | No | ||
46 | COPZ1 | 6940100 | 3281 | 0.099 | 0.5049 | No | ||
47 | RAB3IL1 | 380685 5420176 | 3325 | 0.096 | 0.5040 | No | ||
48 | GPX1 | 4150093 | 3336 | 0.095 | 0.5049 | No | ||
49 | ALDH6A1 | 1770746 | 3398 | 0.090 | 0.5030 | No | ||
50 | NCOA6 | 1780333 6450110 | 3413 | 0.089 | 0.5036 | No | ||
51 | TCF12 | 3610324 7000156 | 3512 | 0.081 | 0.4995 | No | ||
52 | TCERG1 | 2350551 4540397 5220746 | 3793 | 0.064 | 0.4853 | No | ||
53 | MDM1 | 510528 1780280 2680152 2690181 3060025 3120487 4210601 4540037 4610142 5290110 6400433 6480743 | 3883 | 0.059 | 0.4813 | No | ||
54 | LAMC2 | 450692 2680041 4200059 4670148 | 4016 | 0.053 | 0.4750 | No | ||
55 | SIRT1 | 1190731 | 4282 | 0.043 | 0.4613 | No | ||
56 | DHX35 | 1230440 | 4382 | 0.040 | 0.4565 | No | ||
57 | SYNPO2L | 5390719 | 4460 | 0.037 | 0.4529 | No | ||
58 | C4A | 360286 3830100 5220750 6420132 | 4463 | 0.037 | 0.4533 | No | ||
59 | SSR1 | 5890100 | 4546 | 0.035 | 0.4494 | No | ||
60 | RAB9A | 1690279 3710671 | 4549 | 0.035 | 0.4499 | No | ||
61 | BLNK | 70288 6590092 | 4836 | 0.028 | 0.4348 | No | ||
62 | ETV1 | 70735 2940603 5080463 | 5007 | 0.026 | 0.4259 | No | ||
63 | PPARGC1A | 4670040 | 5467 | 0.019 | 0.4013 | No | ||
64 | PICALM | 1940280 | 5596 | 0.018 | 0.3947 | No | ||
65 | SMCR8 | 730653 | 5867 | 0.016 | 0.3803 | No | ||
66 | POGK | 5290315 | 6284 | 0.013 | 0.3579 | No | ||
67 | ZIC3 | 380020 | 6897 | 0.009 | 0.3249 | No | ||
68 | EIF3S10 | 1190079 3840176 | 6955 | 0.009 | 0.3219 | No | ||
69 | PLS3 | 3290082 | 7056 | 0.009 | 0.3166 | No | ||
70 | LIN28 | 6590672 | 7157 | 0.008 | 0.3113 | No | ||
71 | DNMT3A | 4050068 4810717 | 7337 | 0.008 | 0.3017 | No | ||
72 | PIK3R1 | 4730671 | 7437 | 0.007 | 0.2965 | No | ||
73 | HNRPD | 4120021 | 7933 | 0.005 | 0.2697 | No | ||
74 | XPO1 | 540707 | 7981 | 0.005 | 0.2672 | No | ||
75 | TYR | 5690139 | 7994 | 0.005 | 0.2667 | No | ||
76 | SEMA3A | 1780064 | 8102 | 0.005 | 0.2609 | No | ||
77 | HNRPH2 | 2630040 5720671 | 8122 | 0.005 | 0.2600 | No | ||
78 | FOXD3 | 6550156 | 8199 | 0.005 | 0.2559 | No | ||
79 | APLN | 6620632 | 8205 | 0.005 | 0.2557 | No | ||
80 | VLDLR | 870722 3060047 5340452 6550131 | 8325 | 0.004 | 0.2493 | No | ||
81 | NPTX1 | 3710736 | 8394 | 0.004 | 0.2457 | No | ||
82 | HOXC5 | 1580017 | 8463 | 0.004 | 0.2421 | No | ||
83 | FZD6 | 360288 | 8479 | 0.004 | 0.2413 | No | ||
84 | SOX10 | 6200538 | 8494 | 0.004 | 0.2406 | No | ||
85 | IRS4 | 430341 1190450 | 8526 | 0.004 | 0.2390 | No | ||
86 | SLC17A2 | 870593 2810035 | 8566 | 0.004 | 0.2369 | No | ||
87 | CRLF1 | 3520092 | 8649 | 0.003 | 0.2325 | No | ||
88 | SLC1A7 | 1990181 | 8710 | 0.003 | 0.2293 | No | ||
89 | HOXD10 | 6100039 | 8737 | 0.003 | 0.2280 | No | ||
90 | GLA | 4610364 | 8755 | 0.003 | 0.2271 | No | ||
91 | ARMET | 5130670 | 9007 | 0.002 | 0.2135 | No | ||
92 | UBXD2 | 4280092 | 9010 | 0.002 | 0.2134 | No | ||
93 | GZMK | 1410148 | 9036 | 0.002 | 0.2121 | No | ||
94 | AP1S2 | 780279 4280707 | 9240 | 0.002 | 0.2011 | No | ||
95 | NPM1 | 4730427 | 9338 | 0.001 | 0.1959 | No | ||
96 | MTHFD1 | 5900398 6520427 | 9650 | 0.000 | 0.1790 | No | ||
97 | CPT1A | 6350093 | 9668 | 0.000 | 0.1781 | No | ||
98 | VNN1 | 3940400 | 9823 | -0.000 | 0.1697 | No | ||
99 | HOXA11 | 6980133 | 9946 | -0.000 | 0.1631 | No | ||
100 | FMR1 | 5050075 | 9995 | -0.001 | 0.1605 | No | ||
101 | BMP6 | 2100128 | 10136 | -0.001 | 0.1530 | No | ||
102 | CLCN5 | 4200390 | 10276 | -0.001 | 0.1454 | No | ||
103 | OMG | 6760066 | 10592 | -0.002 | 0.1284 | No | ||
104 | TNRC15 | 6760746 | 10769 | -0.003 | 0.1189 | No | ||
105 | RHOQ | 520161 | 11000 | -0.003 | 0.1065 | No | ||
106 | NEUROD1 | 3060619 | 11107 | -0.004 | 0.1008 | No | ||
107 | TOM1L2 | 4810465 | 11228 | -0.004 | 0.0943 | No | ||
108 | LHFP | 3440368 | 11264 | -0.004 | 0.0925 | No | ||
109 | TESK2 | 6520524 | 11378 | -0.005 | 0.0865 | No | ||
110 | FGF14 | 2630390 3520075 6770048 | 11478 | -0.005 | 0.0812 | No | ||
111 | TGFB2 | 4920292 | 11752 | -0.006 | 0.0664 | No | ||
112 | BDNF | 2940128 3520368 | 11795 | -0.006 | 0.0643 | No | ||
113 | CARKL | 6020068 | 11955 | -0.007 | 0.0557 | No | ||
114 | RNF128 | 1230300 5670273 | 12182 | -0.008 | 0.0436 | No | ||
115 | PFKFB1 | 2370128 | 12202 | -0.008 | 0.0427 | No | ||
116 | CAPN6 | 1740168 | 12459 | -0.009 | 0.0290 | No | ||
117 | SUMF1 | 730050 | 12581 | -0.010 | 0.0225 | No | ||
118 | HOXB5 | 2900538 | 12615 | -0.010 | 0.0209 | No | ||
119 | CREB5 | 2320368 | 12683 | -0.010 | 0.0174 | No | ||
120 | GGN | 1410528 4210082 5290170 | 12724 | -0.011 | 0.0154 | No | ||
121 | SEC23IP | 4540484 6200047 | 12923 | -0.012 | 0.0049 | No | ||
122 | KCNE4 | 2470102 | 12955 | -0.012 | 0.0034 | No | ||
123 | CALR | 510446 | 13071 | -0.013 | -0.0027 | No | ||
124 | MAX | 5220021 | 13089 | -0.013 | -0.0034 | No | ||
125 | SLC31A2 | 1450577 | 13220 | -0.014 | -0.0102 | No | ||
126 | CBX5 | 3830072 6290167 | 13476 | -0.016 | -0.0238 | No | ||
127 | DUSP8 | 6650039 | 13522 | -0.017 | -0.0260 | No | ||
128 | TAC1 | 7000195 380706 | 13737 | -0.019 | -0.0373 | No | ||
129 | ELAVL3 | 2850014 | 13742 | -0.019 | -0.0373 | No | ||
130 | UBE2B | 4780497 | 13779 | -0.020 | -0.0389 | No | ||
131 | LRP5 | 2100397 3170484 | 13814 | -0.020 | -0.0405 | No | ||
132 | NRIP3 | 1340372 | 14131 | -0.025 | -0.0572 | No | ||
133 | GTF2A1 | 4120138 4920524 5390110 1230397 | 14292 | -0.028 | -0.0655 | No | ||
134 | DUSP7 | 2940309 | 14367 | -0.029 | -0.0690 | No | ||
135 | NFX1 | 450504 | 14588 | -0.035 | -0.0804 | No | ||
136 | RPS28 | 3830221 | 14895 | -0.046 | -0.0963 | No | ||
137 | CYR61 | 1240408 5290026 4120452 6550008 | 15026 | -0.053 | -0.1026 | No | ||
138 | BTBD14B | 3520601 4280162 | 15087 | -0.057 | -0.1050 | No | ||
139 | HOXB7 | 4540706 4610358 | 15138 | -0.060 | -0.1068 | No | ||
140 | DVL2 | 6110162 | 15246 | -0.068 | -0.1115 | No | ||
141 | EIF4E | 1580403 70133 6380215 | 15251 | -0.069 | -0.1107 | No | ||
142 | STK16 | 1740154 | 15346 | -0.075 | -0.1147 | No | ||
143 | SLC39A5 | 2900100 4610440 | 15389 | -0.079 | -0.1157 | No | ||
144 | LAMA3 | 1190131 5290239 | 15423 | -0.082 | -0.1163 | No | ||
145 | GNB2 | 2350053 | 15493 | -0.088 | -0.1187 | No | ||
146 | NDUFA7 | 5900722 | 15495 | -0.088 | -0.1174 | No | ||
147 | EGLN2 | 540086 | 15541 | -0.093 | -0.1184 | No | ||
148 | TOP3A | 7000435 | 15584 | -0.099 | -0.1192 | No | ||
149 | HIVEP1 | 3850632 | 15782 | -0.119 | -0.1281 | No | ||
150 | SLC12A6 | 610278 1980035 5340671 | 15789 | -0.119 | -0.1266 | No | ||
151 | COQ4 | 1660551 | 15863 | -0.128 | -0.1286 | No | ||
152 | DCTN4 | 3390010 5550170 | 15930 | -0.134 | -0.1302 | No | ||
153 | SESN3 | 110687 | 16200 | -0.171 | -0.1422 | No | ||
154 | FEN1 | 1770541 | 16424 | -0.209 | -0.1511 | No | ||
155 | UROD | 2470494 | 16465 | -0.217 | -0.1500 | No | ||
156 | MAT2A | 4070026 4730079 6020280 | 16466 | -0.218 | -0.1466 | No | ||
157 | MAP4K1 | 4060692 | 16525 | -0.231 | -0.1463 | No | ||
158 | COMMD8 | 5890358 | 16660 | -0.261 | -0.1496 | No | ||
159 | ILF3 | 940722 3190647 6520110 | 16711 | -0.273 | -0.1482 | No | ||
160 | PPM1A | 1170301 5900273 | 16805 | -0.296 | -0.1487 | No | ||
161 | MTCH2 | 3780603 6620215 | 16840 | -0.304 | -0.1460 | No | ||
162 | UBE2L6 | 60048 1170687 | 16851 | -0.307 | -0.1419 | No | ||
163 | SLC23A2 | 6660722 | 16927 | -0.327 | -0.1410 | No | ||
164 | CHD4 | 5420059 6130338 6380717 | 17136 | -0.395 | -0.1462 | No | ||
165 | SQSTM1 | 6550056 | 17307 | -0.456 | -0.1485 | No | ||
166 | DUSP1 | 6860121 | 17371 | -0.483 | -0.1446 | No | ||
167 | DDIT3 | 780373 | 17490 | -0.535 | -0.1429 | No | ||
168 | BRDT | 3940102 | 17613 | -0.600 | -0.1404 | No | ||
169 | DNAJB5 | 2900215 | 17628 | -0.611 | -0.1319 | No | ||
170 | CTNS | 4480048 | 17725 | -0.670 | -0.1269 | No | ||
171 | GABARAP | 1450286 | 17808 | -0.719 | -0.1205 | No | ||
172 | RUNX1 | 3840711 | 17835 | -0.736 | -0.1107 | No | ||
173 | KBTBD2 | 2320014 | 18048 | -0.935 | -0.1080 | No | ||
174 | PIP5K1A | 4560672 | 18136 | -1.032 | -0.0971 | No | ||
175 | ZFYVE26 | 6860152 | 18188 | -1.106 | -0.0831 | No | ||
176 | ATF7IP | 2690176 6770021 | 18306 | -1.342 | -0.0691 | No | ||
177 | EPC1 | 1570050 5290095 6900193 | 18379 | -1.571 | -0.0491 | No | ||
178 | NIT1 | 1230338 3940671 | 18488 | -2.027 | -0.0242 | No | ||
179 | ISGF3G | 3190131 7100142 | 18490 | -2.051 | 0.0068 | No |