Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
Upregulated in class | absentNotch |
GeneSet | V$NMYC_01 |
Enrichment Score (ES) | 0.66211283 |
Normalized Enrichment Score (NES) | 1.5786244 |
Nominal p-value | 0.0 |
FDR q-value | 0.1829349 |
FWER p-Value | 0.388 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PABPC1 | 2650180 2690253 6020632 1990270 | 3 | 6.314 | 0.0934 | Yes | ||
2 | TIMM10 | 610070 1450019 | 12 | 4.552 | 0.1605 | Yes | ||
3 | PABPC4 | 1990170 6760270 5390138 | 20 | 4.232 | 0.2228 | Yes | ||
4 | HMOX1 | 1740687 | 30 | 3.784 | 0.2784 | Yes | ||
5 | CEBPB | 2970019 | 196 | 1.950 | 0.2984 | Yes | ||
6 | SH3KBP1 | 670102 2850458 7000309 | 219 | 1.839 | 0.3244 | Yes | ||
7 | ATAD3A | 4050288 | 292 | 1.547 | 0.3435 | Yes | ||
8 | GJA1 | 5220731 | 295 | 1.543 | 0.3662 | Yes | ||
9 | VARS2 | 1410017 3800114 4210270 | 330 | 1.473 | 0.3862 | Yes | ||
10 | PRDX4 | 3800039 | 331 | 1.472 | 0.4081 | Yes | ||
11 | FBL | 5130020 | 398 | 1.351 | 0.4245 | Yes | ||
12 | IPO4 | 5050619 | 451 | 1.250 | 0.4402 | Yes | ||
13 | HSPD1 | 60097 2030451 | 452 | 1.249 | 0.4587 | Yes | ||
14 | GADD45G | 2510142 | 458 | 1.243 | 0.4769 | Yes | ||
15 | U2AF2 | 450600 4670128 5420292 | 459 | 1.236 | 0.4952 | Yes | ||
16 | PPAT | 1980019 | 515 | 1.138 | 0.5091 | Yes | ||
17 | NR1D1 | 2360471 770746 6590204 | 543 | 1.102 | 0.5240 | Yes | ||
18 | NOL5A | 5570139 | 571 | 1.069 | 0.5383 | Yes | ||
19 | ATP5G1 | 5290019 | 647 | 0.984 | 0.5489 | Yes | ||
20 | EIF4B | 5390563 5270577 | 688 | 0.933 | 0.5605 | Yes | ||
21 | GPD1 | 2480095 | 747 | 0.885 | 0.5705 | Yes | ||
22 | G6PC3 | 1580487 5390253 | 789 | 0.849 | 0.5809 | Yes | ||
23 | PA2G4 | 2030463 | 823 | 0.827 | 0.5913 | Yes | ||
24 | HSPE1 | 3170438 | 845 | 0.815 | 0.6023 | Yes | ||
25 | BCL7C | 460050 | 848 | 0.812 | 0.6142 | Yes | ||
26 | VPS16 | 430064 3390041 6860301 | 885 | 0.786 | 0.6239 | Yes | ||
27 | HYAL2 | 1500152 | 952 | 0.749 | 0.6314 | Yes | ||
28 | DLX1 | 360168 | 1042 | 0.689 | 0.6368 | Yes | ||
29 | PES1 | 2470427 | 1195 | 0.610 | 0.6376 | Yes | ||
30 | FKBP5 | 2190048 | 1218 | 0.596 | 0.6452 | Yes | ||
31 | RPL22 | 4070070 | 1319 | 0.549 | 0.6480 | Yes | ||
32 | FKBP10 | 1340706 | 1365 | 0.525 | 0.6533 | Yes | ||
33 | LMNB1 | 5890292 6020008 | 1526 | 0.464 | 0.6515 | Yes | ||
34 | GTPBP1 | 2230541 4560528 | 1580 | 0.443 | 0.6552 | Yes | ||
35 | LIG3 | 2940300 | 1680 | 0.410 | 0.6559 | Yes | ||
36 | POLR3E | 380152 | 1681 | 0.410 | 0.6620 | Yes | ||
37 | COPS7A | 3940458 7000022 | 1848 | 0.360 | 0.6583 | Yes | ||
38 | SRP72 | 3990427 | 1920 | 0.340 | 0.6595 | Yes | ||
39 | HMGN2 | 3140091 | 1962 | 0.326 | 0.6621 | Yes | ||
40 | EIF4G1 | 4070446 | 2101 | 0.290 | 0.6589 | No | ||
41 | FHOD1 | 2680279 | 2286 | 0.246 | 0.6526 | No | ||
42 | ELOVL6 | 5340746 | 2378 | 0.226 | 0.6510 | No | ||
43 | KRTCAP2 | 5220040 | 2490 | 0.206 | 0.6481 | No | ||
44 | ZCCHC7 | 6510592 | 2660 | 0.175 | 0.6415 | No | ||
45 | PPARGC1B | 3290114 | 2856 | 0.146 | 0.6331 | No | ||
46 | TPM2 | 520735 3870390 | 2996 | 0.128 | 0.6274 | No | ||
47 | RBM3 | 2360739 5700167 | 3096 | 0.118 | 0.6238 | No | ||
48 | PSEN2 | 130382 | 3230 | 0.104 | 0.6181 | No | ||
49 | CACNA1D | 1740315 4730731 | 3233 | 0.103 | 0.6196 | No | ||
50 | B4GALT2 | 780037 | 3257 | 0.101 | 0.6198 | No | ||
51 | CDC14A | 4050132 | 3274 | 0.100 | 0.6204 | No | ||
52 | CTSF | 6100021 | 3285 | 0.099 | 0.6214 | No | ||
53 | MYST3 | 5270500 | 3341 | 0.094 | 0.6198 | No | ||
54 | RBBP6 | 2320129 | 3567 | 0.078 | 0.6087 | No | ||
55 | RPL13A | 2680519 5700142 | 3580 | 0.077 | 0.6092 | No | ||
56 | NRAS | 6900577 | 3584 | 0.077 | 0.6102 | No | ||
57 | CTBP2 | 430309 3710079 | 3596 | 0.076 | 0.6107 | No | ||
58 | ATP6V0B | 2810112 | 3618 | 0.075 | 0.6107 | No | ||
59 | AMPD2 | 630093 1170070 | 3791 | 0.064 | 0.6023 | No | ||
60 | SOX12 | 1780037 | 4066 | 0.051 | 0.5882 | No | ||
61 | MAPKAPK3 | 630520 | 4093 | 0.050 | 0.5875 | No | ||
62 | NR5A1 | 70707 | 4389 | 0.040 | 0.5721 | No | ||
63 | XRN2 | 130603 1230113 4230309 | 4509 | 0.036 | 0.5662 | No | ||
64 | ADCY3 | 2350347 3440242 | 4516 | 0.036 | 0.5664 | No | ||
65 | RAD9A | 110300 1940632 3990390 6040014 | 4563 | 0.035 | 0.5644 | No | ||
66 | BARHL1 | 4210113 | 4661 | 0.032 | 0.5597 | No | ||
67 | TIAL1 | 4150048 6510605 | 4920 | 0.027 | 0.5461 | No | ||
68 | GPC3 | 6180735 | 4927 | 0.027 | 0.5462 | No | ||
69 | BAI2 | 380632 630113 6650170 | 4972 | 0.026 | 0.5442 | No | ||
70 | ETV1 | 70735 2940603 5080463 | 5007 | 0.026 | 0.5427 | No | ||
71 | ARRDC3 | 4610390 | 5195 | 0.023 | 0.5329 | No | ||
72 | DUSP4 | 2690044 2850593 | 5223 | 0.022 | 0.5317 | No | ||
73 | SC5DL | 6650390 | 5326 | 0.021 | 0.5265 | No | ||
74 | COL2A1 | 460446 3940500 | 5364 | 0.021 | 0.5248 | No | ||
75 | SEMA7A | 2630239 5050593 | 5435 | 0.020 | 0.5213 | No | ||
76 | NXPH1 | 3870546 | 5490 | 0.019 | 0.5187 | No | ||
77 | PANK3 | 3060687 | 5832 | 0.016 | 0.5004 | No | ||
78 | NEUROD2 | 5290097 | 5838 | 0.016 | 0.5004 | No | ||
79 | GPS1 | 2470037 4760315 6200528 7100040 | 5894 | 0.016 | 0.4976 | No | ||
80 | SOCS5 | 3830398 7100093 | 5972 | 0.015 | 0.4937 | No | ||
81 | JPH1 | 610739 | 6272 | 0.013 | 0.4777 | No | ||
82 | ADAMTS17 | 6510739 | 6278 | 0.013 | 0.4776 | No | ||
83 | POGK | 5290315 | 6284 | 0.013 | 0.4775 | No | ||
84 | RTN4RL2 | 6450609 | 6497 | 0.012 | 0.4662 | No | ||
85 | STMN4 | 2900091 | 6813 | 0.010 | 0.4492 | No | ||
86 | SLC12A5 | 1980692 | 6881 | 0.009 | 0.4457 | No | ||
87 | LIN28 | 6590672 | 7157 | 0.008 | 0.4309 | No | ||
88 | NRXN1 | 460408 5340270 6370066 | 7238 | 0.008 | 0.4267 | No | ||
89 | NKX2-2 | 4150731 | 7316 | 0.008 | 0.4227 | No | ||
90 | AKAP10 | 2630504 5910577 | 7317 | 0.008 | 0.4228 | No | ||
91 | DNMT3A | 4050068 4810717 | 7337 | 0.008 | 0.4219 | No | ||
92 | RUNX2 | 1400193 4230215 | 7615 | 0.007 | 0.4069 | No | ||
93 | WEE1 | 3390070 | 7696 | 0.006 | 0.4027 | No | ||
94 | SLC38A5 | 540093 | 7813 | 0.006 | 0.3965 | No | ||
95 | ADAM10 | 3780156 | 7915 | 0.006 | 0.3911 | No | ||
96 | PRKCE | 5700053 | 7983 | 0.005 | 0.3875 | No | ||
97 | DNAJB9 | 460114 | 8178 | 0.005 | 0.3771 | No | ||
98 | LAP3 | 2570064 | 8297 | 0.004 | 0.3707 | No | ||
99 | PCDHA10 | 3830725 | 8385 | 0.004 | 0.3661 | No | ||
100 | PLA2G4A | 6380364 | 8462 | 0.004 | 0.3620 | No | ||
101 | SLC17A2 | 870593 2810035 | 8566 | 0.004 | 0.3565 | No | ||
102 | GRIN2A | 6550538 | 8598 | 0.003 | 0.3549 | No | ||
103 | BMP2K | 60541 5570504 | 8691 | 0.003 | 0.3499 | No | ||
104 | HTF9C | 3190048 4120132 | 8807 | 0.003 | 0.3437 | No | ||
105 | NPM1 | 4730427 | 9338 | 0.001 | 0.3150 | No | ||
106 | HS3ST3A1 | 2230497 | 9488 | 0.001 | 0.3069 | No | ||
107 | ALX4 | 3870019 | 9569 | 0.001 | 0.3026 | No | ||
108 | MTHFD1 | 5900398 6520427 | 9650 | 0.000 | 0.2983 | No | ||
109 | ADPRHL1 | 4150133 6650300 | 9709 | 0.000 | 0.2951 | No | ||
110 | FLT3 | 2640487 | 9828 | -0.000 | 0.2887 | No | ||
111 | ABCA1 | 6290156 | 9882 | -0.000 | 0.2859 | No | ||
112 | HPCA | 6860010 | 10122 | -0.001 | 0.2729 | No | ||
113 | TIMM9 | 2450484 | 10264 | -0.001 | 0.2653 | No | ||
114 | EN2 | 7000368 | 10885 | -0.003 | 0.2317 | No | ||
115 | B3GALT2 | 430136 | 11078 | -0.004 | 0.2214 | No | ||
116 | ANGPT2 | 1230458 5720706 6040605 | 11202 | -0.004 | 0.2147 | No | ||
117 | CHRM1 | 4280619 | 11231 | -0.004 | 0.2133 | No | ||
118 | NUP153 | 7000452 | 11299 | -0.005 | 0.2097 | No | ||
119 | TESK2 | 6520524 | 11378 | -0.005 | 0.2056 | No | ||
120 | LHX9 | 2350112 | 11515 | -0.005 | 0.1983 | No | ||
121 | CUGBP1 | 450292 510022 7050176 7050215 | 11641 | -0.006 | 0.1916 | No | ||
122 | SNCAIP | 4010551 | 11782 | -0.006 | 0.1841 | No | ||
123 | RCL1 | 1980408 2680008 3800176 | 11839 | -0.006 | 0.1811 | No | ||
124 | FGF11 | 840292 | 11845 | -0.006 | 0.1810 | No | ||
125 | NDUFS1 | 2650253 | 11846 | -0.006 | 0.1811 | No | ||
126 | APOA5 | 6130471 | 11913 | -0.007 | 0.1776 | No | ||
127 | POU3F1 | 3710022 | 11951 | -0.007 | 0.1757 | No | ||
128 | RNF128 | 1230300 5670273 | 12182 | -0.008 | 0.1633 | No | ||
129 | SEPT3 | 3830022 5290079 | 12235 | -0.008 | 0.1606 | No | ||
130 | KIAA0427 | 1690435 | 12337 | -0.009 | 0.1553 | No | ||
131 | HOXC13 | 4070722 | 12441 | -0.009 | 0.1498 | No | ||
132 | NEUROD6 | 4670731 | 12460 | -0.009 | 0.1490 | No | ||
133 | EIF3S1 | 6130368 6770044 | 12499 | -0.009 | 0.1471 | No | ||
134 | SCFD2 | 2480504 | 12715 | -0.011 | 0.1356 | No | ||
135 | DLC1 | 1090632 6450594 | 12761 | -0.011 | 0.1333 | No | ||
136 | MAX | 5220021 | 13089 | -0.013 | 0.1157 | No | ||
137 | HHIP | 6940438 | 13190 | -0.014 | 0.1105 | No | ||
138 | GRK6 | 1500053 | 13347 | -0.015 | 0.1023 | No | ||
139 | SGTB | 460170 | 13460 | -0.016 | 0.0964 | No | ||
140 | ENPP6 | 110524 580563 | 13651 | -0.018 | 0.0864 | No | ||
141 | CHST11 | 6760546 | 13822 | -0.020 | 0.0775 | No | ||
142 | PLAGL1 | 3190082 6200193 | 13856 | -0.021 | 0.0760 | No | ||
143 | MCM8 | 6130743 | 14235 | -0.027 | 0.0559 | No | ||
144 | GNA13 | 4590102 | 14479 | -0.032 | 0.0432 | No | ||
145 | SFXN2 | 2650563 3140095 3830762 3870398 | 14573 | -0.034 | 0.0387 | No | ||
146 | RXRB | 1780040 5340438 | 14746 | -0.040 | 0.0299 | No | ||
147 | PLAG1 | 1450142 3870139 6520039 | 14865 | -0.045 | 0.0242 | No | ||
148 | HRH3 | 6180040 | 14975 | -0.051 | 0.0190 | No | ||
149 | KCNK5 | 4590504 6860687 | 14982 | -0.051 | 0.0195 | No | ||
150 | HOXB7 | 4540706 4610358 | 15138 | -0.060 | 0.0119 | No | ||
151 | ARF6 | 3520026 | 15180 | -0.063 | 0.0107 | No | ||
152 | RAMP2 | 6860037 | 15230 | -0.067 | 0.0090 | No | ||
153 | ZZZ3 | 780133 2320239 2640452 5080706 6550341 | 15397 | -0.080 | 0.0012 | No | ||
154 | GADD45B | 2350408 | 15439 | -0.083 | 0.0002 | No | ||
155 | TLE3 | 580040 4730121 | 15535 | -0.093 | -0.0036 | No | ||
156 | MNT | 4920575 | 15554 | -0.096 | -0.0031 | No | ||
157 | SEMA3F | 5420601 6770731 | 15577 | -0.098 | -0.0029 | No | ||
158 | IPO13 | 3870088 | 15655 | -0.106 | -0.0055 | No | ||
159 | HRSP12 | 610136 2510133 4280561 2760047 | 15695 | -0.110 | -0.0060 | No | ||
160 | PFN1 | 6130132 | 15921 | -0.133 | -0.0162 | No | ||
161 | USP2 | 1190292 1240253 4850035 | 16083 | -0.156 | -0.0226 | No | ||
162 | CLCN2 | 1940021 | 16149 | -0.164 | -0.0237 | No | ||
163 | SCYL1 | 5050717 | 16201 | -0.172 | -0.0240 | No | ||
164 | TOP1 | 770471 4060632 6650324 | 16236 | -0.176 | -0.0232 | No | ||
165 | UBE1 | 4150139 7050463 | 16334 | -0.191 | -0.0256 | No | ||
166 | SLC20A1 | 6420014 | 16362 | -0.197 | -0.0242 | No | ||
167 | BCL2 | 730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164 | 16536 | -0.234 | -0.0301 | No | ||
168 | ANXA6 | 2190014 | 16582 | -0.244 | -0.0289 | No | ||
169 | PDK2 | 2690017 | 16623 | -0.253 | -0.0273 | No | ||
170 | ZHX2 | 2900452 | 16790 | -0.289 | -0.0320 | No | ||
171 | PFKFB3 | 630706 | 17072 | -0.370 | -0.0418 | No | ||
172 | MXD4 | 4810113 | 17661 | -0.632 | -0.0643 | No | ||
173 | AP1GBP1 | 2510372 | 17916 | -0.798 | -0.0662 | No | ||
174 | RPIA | 780079 | 18011 | -0.885 | -0.0582 | No | ||
175 | STAT3 | 460040 3710341 | 18021 | -0.893 | -0.0455 | No | ||
176 | WBP2 | 3170128 | 18054 | -0.942 | -0.0332 | No | ||
177 | HBP1 | 2510102 3130010 4210619 | 18447 | -1.783 | -0.0281 | No | ||
178 | TEF | 1050050 3120397 4060487 | 18538 | -2.509 | 0.0042 | No |