Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | V$NFKB_C |
Enrichment Score (ES) | -0.6208781 |
Normalized Enrichment Score (NES) | -1.5967988 |
Nominal p-value | 0.0 |
FDR q-value | 0.28401715 |
FWER p-Value | 0.335 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PCBP4 | 6350722 | 58 | 3.150 | 0.0495 | No | ||
2 | ARHGAP8 | 380333 5390487 | 429 | 1.303 | 0.0512 | No | ||
3 | TCEA2 | 6370546 | 503 | 1.153 | 0.0664 | No | ||
4 | NDRG2 | 450403 | 766 | 0.868 | 0.0667 | No | ||
5 | ENO3 | 5270136 | 1086 | 0.660 | 0.0605 | No | ||
6 | BMF | 610102 | 1094 | 0.658 | 0.0711 | No | ||
7 | VCAM1 | 2900450 | 1185 | 0.613 | 0.0764 | No | ||
8 | BHLHB2 | 7040603 | 1201 | 0.607 | 0.0857 | No | ||
9 | NFKBIB | 2260167 | 1352 | 0.533 | 0.0865 | No | ||
10 | PRKCD | 770592 | 1698 | 0.405 | 0.0745 | No | ||
11 | CYLD | 6590079 | 1812 | 0.370 | 0.0746 | No | ||
12 | AMOTL1 | 380279 | 1978 | 0.323 | 0.0710 | No | ||
13 | CDC37 | 2570537 | 2001 | 0.317 | 0.0751 | No | ||
14 | SMARCAD1 | 5390619 | 2201 | 0.265 | 0.0688 | No | ||
15 | RAD18 | 5670372 | 2236 | 0.256 | 0.0712 | No | ||
16 | LASP1 | 1690528 2190341 6420341 | 2364 | 0.230 | 0.0681 | No | ||
17 | SEC14L2 | 2640370 | 2416 | 0.220 | 0.0690 | No | ||
18 | ANP32A | 510044 1580095 2680037 | 2535 | 0.197 | 0.0659 | No | ||
19 | LAMB3 | 7100301 | 2540 | 0.195 | 0.0690 | No | ||
20 | SNX15 | 1240348 6770082 | 2633 | 0.179 | 0.0670 | No | ||
21 | TYRO3 | 3130193 | 2664 | 0.175 | 0.0683 | No | ||
22 | RAP2C | 1690132 | 2779 | 0.157 | 0.0647 | No | ||
23 | BCKDK | 1940601 3990600 | 2994 | 0.129 | 0.0552 | No | ||
24 | ZADH2 | 520438 | 3011 | 0.127 | 0.0565 | No | ||
25 | CDC14A | 4050132 | 3274 | 0.100 | 0.0439 | No | ||
26 | IL27RA | 940093 | 3277 | 0.100 | 0.0455 | No | ||
27 | DAP3 | 1660528 2120039 5420593 | 3361 | 0.093 | 0.0425 | No | ||
28 | WRN | 540687 1240093 | 3477 | 0.083 | 0.0377 | No | ||
29 | EGR3 | 6940128 | 3745 | 0.067 | 0.0243 | No | ||
30 | ASH1L | 2510402 5360687 6650685 | 4076 | 0.051 | 0.0073 | No | ||
31 | CDK6 | 4920253 | 4077 | 0.051 | 0.0081 | No | ||
32 | GPHN | 3290195 3840121 | 4177 | 0.047 | 0.0035 | No | ||
33 | TNFSF18 | 1990458 2850520 | 4247 | 0.044 | 0.0005 | No | ||
34 | EGF | 5220154 | 4268 | 0.043 | 0.0002 | No | ||
35 | CLCN1 | 840161 | 4387 | 0.040 | -0.0056 | No | ||
36 | SESN2 | 2370019 | 4670 | 0.032 | -0.0203 | No | ||
37 | LRRFIP2 | 670575 730152 6590438 | 4693 | 0.032 | -0.0210 | No | ||
38 | CTGF | 4540577 | 4717 | 0.031 | -0.0217 | No | ||
39 | NFAT5 | 2510411 5890195 6550152 | 4733 | 0.031 | -0.0220 | No | ||
40 | SNAP25 | 360520 | 4885 | 0.028 | -0.0298 | No | ||
41 | FTHL17 | 6550193 | 4929 | 0.027 | -0.0317 | No | ||
42 | BAI2 | 380632 630113 6650170 | 4972 | 0.026 | -0.0335 | No | ||
43 | PLA1A | 4590040 6100204 | 4997 | 0.026 | -0.0344 | No | ||
44 | TRIM47 | 5080717 | 4999 | 0.026 | -0.0340 | No | ||
45 | PPP3CA | 4760332 6760092 | 5029 | 0.025 | -0.0351 | No | ||
46 | SLC6A12 | 3170685 | 5178 | 0.023 | -0.0428 | No | ||
47 | GRK5 | 1940348 4670053 | 5251 | 0.022 | -0.0463 | No | ||
48 | IL13 | 7040021 | 5371 | 0.021 | -0.0524 | No | ||
49 | BCL3 | 3990440 | 5383 | 0.020 | -0.0527 | No | ||
50 | HSD3B7 | 1410129 | 5419 | 0.020 | -0.0543 | No | ||
51 | IFNB1 | 1400142 | 5487 | 0.019 | -0.0576 | No | ||
52 | RALGDS | 430463 | 5840 | 0.016 | -0.0764 | No | ||
53 | PTGS2 | 2510301 3170369 | 6247 | 0.013 | -0.0982 | No | ||
54 | SIRT2 | 630494 | 6271 | 0.013 | -0.0993 | No | ||
55 | MLLT6 | 3870168 | 6281 | 0.013 | -0.0995 | No | ||
56 | PTGES | 1690075 | 6425 | 0.012 | -0.1071 | No | ||
57 | SMPD3 | 520164 | 6448 | 0.012 | -0.1081 | No | ||
58 | EFNA3 | 6370390 | 6659 | 0.011 | -0.1193 | No | ||
59 | DACH2 | 460605 1500253 | 6779 | 0.010 | -0.1256 | No | ||
60 | PHF6 | 3120632 3990041 | 6832 | 0.010 | -0.1283 | No | ||
61 | ECT2 | 3830086 | 6975 | 0.009 | -0.1358 | No | ||
62 | RIN2 | 2450184 | 7082 | 0.009 | -0.1414 | No | ||
63 | LIN28 | 6590672 | 7157 | 0.008 | -0.1453 | No | ||
64 | DNAJA1 | 1660010 2320358 6840136 | 7468 | 0.007 | -0.1620 | No | ||
65 | PTPRJ | 4010707 | 7524 | 0.007 | -0.1649 | No | ||
66 | MAP3K13 | 3190017 | 7593 | 0.007 | -0.1684 | No | ||
67 | IL2 | 1770725 | 8136 | 0.005 | -0.1978 | No | ||
68 | FOXD3 | 6550156 | 8199 | 0.005 | -0.2011 | No | ||
69 | CUEDC1 | 1660463 | 8295 | 0.004 | -0.2061 | No | ||
70 | SOX10 | 6200538 | 8494 | 0.004 | -0.2168 | No | ||
71 | SOX3 | 4570537 | 8774 | 0.003 | -0.2319 | No | ||
72 | FGF17 | 3130022 | 8849 | 0.003 | -0.2359 | No | ||
73 | IL1A | 3610056 | 8910 | 0.003 | -0.2391 | No | ||
74 | MSX1 | 2650309 | 8972 | 0.002 | -0.2424 | No | ||
75 | TNFSF15 | 360341 | 9125 | 0.002 | -0.2506 | No | ||
76 | VNN3 | 730053 4610609 | 9254 | 0.002 | -0.2575 | No | ||
77 | GNAO1 | 2510292 6590487 | 9289 | 0.001 | -0.2593 | No | ||
78 | TNR | 1340541 | 9341 | 0.001 | -0.2621 | No | ||
79 | CXCL10 | 2450408 | 9427 | 0.001 | -0.2667 | No | ||
80 | IER5 | 2350575 | 9837 | -0.000 | -0.2889 | No | ||
81 | IL27 | 1990324 | 9885 | -0.000 | -0.2914 | No | ||
82 | HOXA11 | 6980133 | 9946 | -0.000 | -0.2946 | No | ||
83 | ARHGAP5 | 2510619 3360035 | 9989 | -0.001 | -0.2969 | No | ||
84 | HOXB6 | 4210739 | 10097 | -0.001 | -0.3027 | No | ||
85 | IL1RN | 2370333 | 10144 | -0.001 | -0.3052 | No | ||
86 | RND1 | 5080300 | 10180 | -0.001 | -0.3071 | No | ||
87 | WNT10A | 2100706 | 10190 | -0.001 | -0.3075 | No | ||
88 | GABPB2 | 6130450 7050735 | 10308 | -0.001 | -0.3139 | No | ||
89 | PTHLH | 5290739 | 10686 | -0.002 | -0.3343 | No | ||
90 | EHF | 4560088 | 10719 | -0.003 | -0.3360 | No | ||
91 | RAB10 | 2360008 5890020 | 10751 | -0.003 | -0.3376 | No | ||
92 | JPH3 | 780397 | 10764 | -0.003 | -0.3382 | No | ||
93 | MOBKL2C | 2640088 3830017 | 10964 | -0.003 | -0.3489 | No | ||
94 | NUP153 | 7000452 | 11299 | -0.005 | -0.3670 | No | ||
95 | ALG6 | 4060131 | 11667 | -0.006 | -0.3868 | No | ||
96 | LYPLA2 | 1500112 | 11689 | -0.006 | -0.3879 | No | ||
97 | BDNF | 2940128 3520368 | 11795 | -0.006 | -0.3934 | No | ||
98 | GNG4 | 2630600 | 11983 | -0.007 | -0.4035 | No | ||
99 | CCL22 | 6380086 | 11985 | -0.007 | -0.4034 | No | ||
100 | UBE2I | 2680056 6350446 | 12088 | -0.008 | -0.4088 | No | ||
101 | HOXB9 | 2640687 | 12324 | -0.009 | -0.4214 | No | ||
102 | PAPPA | 4230463 | 12352 | -0.009 | -0.4227 | No | ||
103 | C1QL1 | 2030465 | 12463 | -0.009 | -0.4286 | No | ||
104 | TSNAXIP1 | 1770270 6180577 | 12492 | -0.009 | -0.4299 | No | ||
105 | SEMA3B | 5570563 | 12565 | -0.010 | -0.4337 | No | ||
106 | IL23A | 6290044 | 12726 | -0.011 | -0.4422 | No | ||
107 | FGF1 | 4780435 5670601 | 12756 | -0.011 | -0.4436 | No | ||
108 | DCAMKL1 | 540095 2690092 | 12820 | -0.011 | -0.4468 | No | ||
109 | SOX5 | 2370576 2900167 3190128 5050528 | 13250 | -0.014 | -0.4698 | No | ||
110 | GATA4 | 1410215 2690609 | 13407 | -0.015 | -0.4780 | No | ||
111 | ARPC5 | 1740411 3450300 | 13625 | -0.018 | -0.4895 | No | ||
112 | MAG | 2370037 | 13629 | -0.018 | -0.4894 | No | ||
113 | SP6 | 60484 510452 2690333 | 13718 | -0.019 | -0.4938 | No | ||
114 | COL11A2 | 5130341 | 13798 | -0.020 | -0.4978 | No | ||
115 | TSLP | 730408 1990500 | 13834 | -0.020 | -0.4993 | No | ||
116 | STAT6 | 1190010 5720019 | 13858 | -0.021 | -0.5002 | No | ||
117 | FOS | 1850315 | 14022 | -0.023 | -0.5087 | No | ||
118 | SLC34A3 | 2230242 | 14203 | -0.026 | -0.5180 | No | ||
119 | RGL1 | 1500097 6900450 | 14208 | -0.026 | -0.5178 | No | ||
120 | GRIN2D | 6620372 | 14233 | -0.027 | -0.5187 | No | ||
121 | FOXA3 | 2680121 | 14245 | -0.027 | -0.5188 | No | ||
122 | PCSK2 | 360017 430528 5900619 | 14258 | -0.027 | -0.5190 | No | ||
123 | ASCL3 | 4570484 | 14262 | -0.027 | -0.5187 | No | ||
124 | DUSP22 | 4280010 5550546 | 14361 | -0.029 | -0.5235 | No | ||
125 | LCAT | 6400441 | 14403 | -0.030 | -0.5253 | No | ||
126 | GNA13 | 4590102 | 14479 | -0.032 | -0.5288 | No | ||
127 | CDH5 | 5340487 | 14582 | -0.035 | -0.5338 | No | ||
128 | PIGC | 5690377 | 14627 | -0.036 | -0.5356 | No | ||
129 | DDR1 | 2060044 5220180 | 14631 | -0.036 | -0.5351 | No | ||
130 | BLR1 | 1500300 5420017 | 14670 | -0.037 | -0.5366 | No | ||
131 | SIN3A | 2190121 | 14684 | -0.037 | -0.5366 | No | ||
132 | ITGB4 | 1740021 3840482 | 14703 | -0.038 | -0.5370 | No | ||
133 | PPP1R13B | 4010605 4760181 | 14929 | -0.048 | -0.5484 | No | ||
134 | SLAMF8 | 1230048 | 15022 | -0.053 | -0.5525 | No | ||
135 | FUT7 | 2900736 | 15054 | -0.055 | -0.5532 | No | ||
136 | JAK3 | 70347 3290008 | 15166 | -0.062 | -0.5582 | No | ||
137 | NLK | 2030010 2450041 | 15169 | -0.062 | -0.5573 | No | ||
138 | MSC | 5080139 | 15185 | -0.064 | -0.5570 | No | ||
139 | CHX10 | 3830184 | 15247 | -0.068 | -0.5592 | No | ||
140 | PPP2R5E | 70671 2120056 | 15265 | -0.069 | -0.5590 | No | ||
141 | IL18R1 | 270546 | 15434 | -0.083 | -0.5667 | No | ||
142 | GADD45B | 2350408 | 15439 | -0.083 | -0.5655 | No | ||
143 | FOXD2 | 4210035 | 15489 | -0.088 | -0.5667 | No | ||
144 | TAL1 | 7040239 | 15516 | -0.090 | -0.5666 | No | ||
145 | MNT | 4920575 | 15554 | -0.096 | -0.5670 | No | ||
146 | MAP3K8 | 2940286 | 15842 | -0.125 | -0.5805 | No | ||
147 | PFN1 | 6130132 | 15921 | -0.133 | -0.5825 | No | ||
148 | TOP1 | 770471 4060632 6650324 | 16236 | -0.176 | -0.5966 | No | ||
149 | EDG5 | 2640300 | 16351 | -0.195 | -0.5996 | No | ||
150 | ARHGEF2 | 3360577 | 16369 | -0.198 | -0.5972 | No | ||
151 | FLI1 | 3990142 | 16745 | -0.280 | -0.6129 | No | ||
152 | ZHX2 | 2900452 | 16790 | -0.289 | -0.6104 | No | ||
153 | PURG | 1190593 | 16984 | -0.344 | -0.6151 | Yes | ||
154 | SOCS2 | 4760692 | 17029 | -0.355 | -0.6116 | Yes | ||
155 | BCL11A | 6860369 | 17052 | -0.364 | -0.6067 | Yes | ||
156 | CHD4 | 5420059 6130338 6380717 | 17136 | -0.395 | -0.6046 | Yes | ||
157 | CENTB5 | 5690128 | 17229 | -0.425 | -0.6025 | Yes | ||
158 | NFKBIA | 1570152 | 17293 | -0.450 | -0.5984 | Yes | ||
159 | EIF5A | 1500059 5290022 6370026 | 17308 | -0.457 | -0.5915 | Yes | ||
160 | NFKB2 | 2320670 | 17315 | -0.460 | -0.5841 | Yes | ||
161 | HCFC1 | 2260008 | 17532 | -0.552 | -0.5866 | Yes | ||
162 | UACA | 1190725 | 17555 | -0.565 | -0.5784 | Yes | ||
163 | XPO6 | 3940019 | 17575 | -0.577 | -0.5698 | Yes | ||
164 | ICAM1 | 6980138 | 17634 | -0.612 | -0.5627 | Yes | ||
165 | CGGBP1 | 4810053 | 17727 | -0.671 | -0.5565 | Yes | ||
166 | IRF1 | 2340152 3450592 6290121 6980577 | 17795 | -0.709 | -0.5483 | Yes | ||
167 | FOXJ2 | 2450441 | 17804 | -0.717 | -0.5368 | Yes | ||
168 | IL2RA | 6620450 | 17824 | -0.729 | -0.5256 | Yes | ||
169 | IL4I1 | 3190161 | 17850 | -0.746 | -0.5145 | Yes | ||
170 | RHOG | 6760575 | 17856 | -0.752 | -0.5022 | Yes | ||
171 | TRIB2 | 4120605 | 17867 | -0.758 | -0.4901 | Yes | ||
172 | TCTA | 2680687 | 17919 | -0.800 | -0.4795 | Yes | ||
173 | RANBP10 | 2340184 | 17944 | -0.819 | -0.4671 | Yes | ||
174 | LCN2 | 2510112 | 17978 | -0.846 | -0.4548 | Yes | ||
175 | BCL2L1 | 1580452 4200152 5420484 | 18009 | -0.884 | -0.4417 | Yes | ||
176 | MRPS6 | 870164 | 18015 | -0.888 | -0.4271 | Yes | ||
177 | TAZ | 7100193 | 18065 | -0.955 | -0.4138 | Yes | ||
178 | USP52 | 3710215 6380133 | 18151 | -1.047 | -0.4009 | Yes | ||
179 | EGR2 | 3800403 | 18301 | -1.337 | -0.3867 | Yes | ||
180 | RORC | 1740121 | 18341 | -1.439 | -0.3648 | Yes | ||
181 | EPHB6 | 5860128 | 18377 | -1.561 | -0.3406 | Yes | ||
182 | CCL5 | 3710397 | 18504 | -2.172 | -0.3111 | Yes | ||
183 | LTB | 3990672 | 18557 | -2.728 | -0.2684 | Yes | ||
184 | S100A10 | 6350010 | 18564 | -2.797 | -0.2220 | Yes | ||
185 | SMOC1 | 840039 | 18589 | -3.340 | -0.1675 | Yes | ||
186 | TNIP1 | 2510279 5900041 6510435 | 18608 | -4.273 | -0.0971 | Yes | ||
187 | RHOA | 580142 5900131 5340450 | 18613 | -5.837 | 0.0002 | Yes |