Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
Upregulated in class | absentNotch |
GeneSet | V$MAX_01 |
Enrichment Score (ES) | 0.5686209 |
Normalized Enrichment Score (NES) | 1.3609567 |
Nominal p-value | 0.021084337 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PABPC1 | 2650180 2690253 6020632 1990270 | 3 | 6.314 | 0.0765 | Yes | ||
2 | TIMM10 | 610070 1450019 | 12 | 4.552 | 0.1313 | Yes | ||
3 | HNRPA1 | 4670398 5050687 | 71 | 2.999 | 0.1646 | Yes | ||
4 | BAX | 3830008 | 131 | 2.296 | 0.1892 | Yes | ||
5 | BOK | 1170373 5860446 | 184 | 2.040 | 0.2112 | Yes | ||
6 | AKAP12 | 1450739 | 186 | 2.035 | 0.2358 | Yes | ||
7 | UBE4B | 780008 3610154 | 235 | 1.731 | 0.2542 | Yes | ||
8 | TFRC | 4050551 | 244 | 1.692 | 0.2743 | Yes | ||
9 | SUPT16H | 1240333 | 252 | 1.677 | 0.2943 | Yes | ||
10 | GJA1 | 5220731 | 295 | 1.543 | 0.3108 | Yes | ||
11 | SLC38A2 | 1470242 3800026 | 359 | 1.422 | 0.3246 | Yes | ||
12 | CAD | 2340717 | 375 | 1.384 | 0.3406 | Yes | ||
13 | PFDN2 | 4230156 | 382 | 1.369 | 0.3569 | Yes | ||
14 | QTRT1 | 1340162 | 409 | 1.328 | 0.3716 | Yes | ||
15 | CFL1 | 2340735 | 431 | 1.297 | 0.3862 | Yes | ||
16 | ATF4 | 730441 1740195 | 464 | 1.227 | 0.3994 | Yes | ||
17 | AATF | 5220575 | 518 | 1.134 | 0.4103 | Yes | ||
18 | NUDC | 4780025 | 524 | 1.127 | 0.4237 | Yes | ||
19 | DDX3X | 2190020 | 528 | 1.119 | 0.4371 | Yes | ||
20 | FKBP11 | 3170575 | 552 | 1.094 | 0.4491 | Yes | ||
21 | TIMM8A | 110279 | 616 | 1.021 | 0.4581 | Yes | ||
22 | CCAR1 | 3190092 | 682 | 0.940 | 0.4660 | Yes | ||
23 | EIF4B | 5390563 5270577 | 688 | 0.933 | 0.4771 | Yes | ||
24 | EIF2C2 | 770451 | 778 | 0.857 | 0.4826 | Yes | ||
25 | PA2G4 | 2030463 | 823 | 0.827 | 0.4903 | Yes | ||
26 | ACY1 | 2360279 6550161 | 875 | 0.796 | 0.4972 | Yes | ||
27 | ASNA1 | 3830041 | 882 | 0.787 | 0.5064 | Yes | ||
28 | VPS16 | 430064 3390041 6860301 | 885 | 0.786 | 0.5158 | Yes | ||
29 | CD164 | 3830594 | 1103 | 0.653 | 0.5120 | Yes | ||
30 | CLN3 | 780368 | 1147 | 0.635 | 0.5174 | Yes | ||
31 | PSME3 | 2810537 | 1170 | 0.621 | 0.5237 | Yes | ||
32 | PER1 | 3290315 | 1217 | 0.596 | 0.5285 | Yes | ||
33 | PTGES2 | 4210097 | 1253 | 0.577 | 0.5336 | Yes | ||
34 | PLCG2 | 5720008 | 1270 | 0.572 | 0.5396 | Yes | ||
35 | PPRC1 | 1740441 | 1271 | 0.572 | 0.5466 | Yes | ||
36 | STMN1 | 1990717 | 1289 | 0.561 | 0.5525 | Yes | ||
37 | SUCLG2 | 5340397 5700270 | 1313 | 0.552 | 0.5579 | Yes | ||
38 | COMMD3 | 2510259 | 1377 | 0.523 | 0.5609 | Yes | ||
39 | MRPL27 | 2060131 | 1449 | 0.496 | 0.5630 | Yes | ||
40 | HMGA1 | 6580408 | 1592 | 0.440 | 0.5607 | Yes | ||
41 | OPRS1 | 6130128 6290717 | 1656 | 0.418 | 0.5623 | Yes | ||
42 | GTF2H1 | 2570746 2650148 | 1763 | 0.390 | 0.5613 | Yes | ||
43 | EEF1B2 | 4850400 6130161 | 1841 | 0.361 | 0.5615 | Yes | ||
44 | PRPS1 | 6350129 | 1900 | 0.346 | 0.5626 | Yes | ||
45 | SRP72 | 3990427 | 1920 | 0.340 | 0.5657 | Yes | ||
46 | QTRTD1 | 7000053 | 1941 | 0.332 | 0.5686 | Yes | ||
47 | ATP6V1C1 | 2690324 5220528 | 2023 | 0.312 | 0.5680 | No | ||
48 | TOPORS | 4060592 | 2376 | 0.227 | 0.5517 | No | ||
49 | TCF4 | 520021 | 2397 | 0.223 | 0.5533 | No | ||
50 | HIRA | 4480609 5270167 | 2472 | 0.210 | 0.5519 | No | ||
51 | TAF6L | 1850056 | 2630 | 0.179 | 0.5455 | No | ||
52 | ZCCHC7 | 6510592 | 2660 | 0.175 | 0.5461 | No | ||
53 | UBXD3 | 5050193 | 2750 | 0.161 | 0.5432 | No | ||
54 | ATP6V1A | 6590242 | 2765 | 0.159 | 0.5444 | No | ||
55 | PTMA | 5570148 | 2997 | 0.128 | 0.5334 | No | ||
56 | TCOF1 | 2680086 | 3029 | 0.125 | 0.5333 | No | ||
57 | RPS2 | 1340647 | 3130 | 0.114 | 0.5292 | No | ||
58 | SNTB2 | 2630014 5390035 | 3174 | 0.110 | 0.5282 | No | ||
59 | RAI14 | 770288 1660075 | 3225 | 0.105 | 0.5268 | No | ||
60 | COPZ1 | 6940100 | 3281 | 0.099 | 0.5250 | No | ||
61 | RAB3IL1 | 380685 5420176 | 3325 | 0.096 | 0.5239 | No | ||
62 | GPX1 | 4150093 | 3336 | 0.095 | 0.5245 | No | ||
63 | ALDH6A1 | 1770746 | 3398 | 0.090 | 0.5223 | No | ||
64 | AMPD2 | 630093 1170070 | 3791 | 0.064 | 0.5018 | No | ||
65 | TCERG1 | 2350551 4540397 5220746 | 3793 | 0.064 | 0.5025 | No | ||
66 | SYT3 | 6380017 | 3804 | 0.063 | 0.5027 | No | ||
67 | EN1 | 5360168 7050025 | 3988 | 0.055 | 0.4935 | No | ||
68 | SIRT1 | 1190731 | 4282 | 0.043 | 0.4781 | No | ||
69 | DHX35 | 1230440 | 4382 | 0.040 | 0.4732 | No | ||
70 | DSCAM | 1780050 2450731 2810438 | 4405 | 0.039 | 0.4725 | No | ||
71 | SSR1 | 5890100 | 4546 | 0.035 | 0.4654 | No | ||
72 | PPP1R3C | 2640170 | 4767 | 0.030 | 0.4538 | No | ||
73 | ETV1 | 70735 2940603 5080463 | 5007 | 0.026 | 0.4411 | No | ||
74 | SYNCRIP | 1690195 3140113 4670279 | 5035 | 0.025 | 0.4400 | No | ||
75 | SLC26A2 | 2360278 | 5053 | 0.025 | 0.4394 | No | ||
76 | PICALM | 1940280 | 5596 | 0.018 | 0.4102 | No | ||
77 | MRPL40 | 2370215 | 6261 | 0.013 | 0.3744 | No | ||
78 | ADAMTS17 | 6510739 | 6278 | 0.013 | 0.3737 | No | ||
79 | POGK | 5290315 | 6284 | 0.013 | 0.3736 | No | ||
80 | EIF3S10 | 1190079 3840176 | 6955 | 0.009 | 0.3373 | No | ||
81 | GUCY1A2 | 1660441 | 7032 | 0.009 | 0.3333 | No | ||
82 | LIN28 | 6590672 | 7157 | 0.008 | 0.3267 | No | ||
83 | DNMT3A | 4050068 4810717 | 7337 | 0.008 | 0.3171 | No | ||
84 | BCOR | 1660452 3940053 | 7426 | 0.007 | 0.3124 | No | ||
85 | AKAP1 | 110148 1740735 2260019 7000563 | 7514 | 0.007 | 0.3078 | No | ||
86 | RUNX2 | 1400193 4230215 | 7615 | 0.007 | 0.3024 | No | ||
87 | SLC38A5 | 540093 | 7813 | 0.006 | 0.2918 | No | ||
88 | XPO1 | 540707 | 7981 | 0.005 | 0.2829 | No | ||
89 | ZBTB10 | 4200132 | 8186 | 0.005 | 0.2718 | No | ||
90 | FOXD3 | 6550156 | 8199 | 0.005 | 0.2713 | No | ||
91 | PCDHA10 | 3830725 | 8385 | 0.004 | 0.2613 | No | ||
92 | NPTX1 | 3710736 | 8394 | 0.004 | 0.2609 | No | ||
93 | HOXC5 | 1580017 | 8463 | 0.004 | 0.2573 | No | ||
94 | SNX5 | 1570021 6860609 | 8488 | 0.004 | 0.2560 | No | ||
95 | IRS4 | 430341 1190450 | 8526 | 0.004 | 0.2540 | No | ||
96 | SLC1A7 | 1990181 | 8710 | 0.003 | 0.2442 | No | ||
97 | HOXD10 | 6100039 | 8737 | 0.003 | 0.2428 | No | ||
98 | ARMET | 5130670 | 9007 | 0.002 | 0.2282 | No | ||
99 | AP1S2 | 780279 4280707 | 9240 | 0.002 | 0.2157 | No | ||
100 | NPM1 | 4730427 | 9338 | 0.001 | 0.2104 | No | ||
101 | ODC1 | 5670168 | 9621 | 0.001 | 0.1951 | No | ||
102 | MTHFD1 | 5900398 6520427 | 9650 | 0.000 | 0.1936 | No | ||
103 | CPT1A | 6350093 | 9668 | 0.000 | 0.1927 | No | ||
104 | LZTFL1 | 540114 | 9911 | -0.000 | 0.1796 | No | ||
105 | HOXA11 | 6980133 | 9946 | -0.000 | 0.1778 | No | ||
106 | BMP6 | 2100128 | 10136 | -0.001 | 0.1675 | No | ||
107 | ATOH8 | 4540204 | 10526 | -0.002 | 0.1465 | No | ||
108 | MEOX2 | 6400288 | 11072 | -0.004 | 0.1170 | No | ||
109 | NEUROD1 | 3060619 | 11107 | -0.004 | 0.1152 | No | ||
110 | OPRD1 | 4280138 | 11248 | -0.004 | 0.1076 | No | ||
111 | TESK2 | 6520524 | 11378 | -0.005 | 0.1007 | No | ||
112 | FGF14 | 2630390 3520075 6770048 | 11478 | -0.005 | 0.0954 | No | ||
113 | TGFB2 | 4920292 | 11752 | -0.006 | 0.0807 | No | ||
114 | SNCAIP | 4010551 | 11782 | -0.006 | 0.0792 | No | ||
115 | RCL1 | 1980408 2680008 3800176 | 11839 | -0.006 | 0.0762 | No | ||
116 | NDUFS1 | 2650253 | 11846 | -0.006 | 0.0760 | No | ||
117 | USP15 | 610592 3520504 | 12087 | -0.008 | 0.0631 | No | ||
118 | SEPT3 | 3830022 5290079 | 12235 | -0.008 | 0.0552 | No | ||
119 | SUMF1 | 730050 | 12581 | -0.010 | 0.0366 | No | ||
120 | HOXB5 | 2900538 | 12615 | -0.010 | 0.0349 | No | ||
121 | GGN | 1410528 4210082 5290170 | 12724 | -0.011 | 0.0292 | No | ||
122 | KCNE4 | 2470102 | 12955 | -0.012 | 0.0169 | No | ||
123 | MAX | 5220021 | 13089 | -0.013 | 0.0098 | No | ||
124 | GATA5 | 430465 | 13132 | -0.013 | 0.0077 | No | ||
125 | SLC31A2 | 1450577 | 13220 | -0.014 | 0.0032 | No | ||
126 | CBX5 | 3830072 6290167 | 13476 | -0.016 | -0.0104 | No | ||
127 | ELAVL3 | 2850014 | 13742 | -0.019 | -0.0246 | No | ||
128 | UBE2B | 4780497 | 13779 | -0.020 | -0.0263 | No | ||
129 | NRIP3 | 1340372 | 14131 | -0.025 | -0.0450 | No | ||
130 | DUSP7 | 2940309 | 14367 | -0.029 | -0.0574 | No | ||
131 | LAMP1 | 2470524 | 14478 | -0.032 | -0.0630 | No | ||
132 | NFX1 | 450504 | 14588 | -0.035 | -0.0685 | No | ||
133 | ZNF318 | 5890091 6130021 | 14887 | -0.046 | -0.0841 | No | ||
134 | HOXB7 | 4540706 4610358 | 15138 | -0.060 | -0.0969 | No | ||
135 | DVL2 | 6110162 | 15246 | -0.068 | -0.1018 | No | ||
136 | EIF4E | 1580403 70133 6380215 | 15251 | -0.069 | -0.1012 | No | ||
137 | GNB2 | 2350053 | 15493 | -0.088 | -0.1132 | No | ||
138 | HHEX | 2340575 | 15654 | -0.106 | -0.1206 | No | ||
139 | IPO13 | 3870088 | 15655 | -0.106 | -0.1193 | No | ||
140 | TOP1 | 770471 4060632 6650324 | 16236 | -0.176 | -0.1486 | No | ||
141 | FEN1 | 1770541 | 16424 | -0.209 | -0.1562 | No | ||
142 | MAT2A | 4070026 4730079 6020280 | 16466 | -0.218 | -0.1558 | No | ||
143 | ANAPC13 | 3800446 | 16547 | -0.238 | -0.1572 | No | ||
144 | PDK2 | 2690017 | 16623 | -0.253 | -0.1582 | No | ||
145 | SMAD2 | 4200592 | 16670 | -0.263 | -0.1575 | No | ||
146 | ILF3 | 940722 3190647 6520110 | 16711 | -0.273 | -0.1564 | No | ||
147 | PPM1A | 1170301 5900273 | 16805 | -0.296 | -0.1579 | No | ||
148 | MTCH2 | 3780603 6620215 | 16840 | -0.304 | -0.1560 | No | ||
149 | CSK | 6350593 | 17026 | -0.354 | -0.1617 | No | ||
150 | CHD4 | 5420059 6130338 6380717 | 17136 | -0.395 | -0.1628 | No | ||
151 | CENTB5 | 5690128 | 17229 | -0.425 | -0.1627 | No | ||
152 | DUSP1 | 6860121 | 17371 | -0.483 | -0.1644 | No | ||
153 | GNAS | 630441 1850373 4050152 | 17449 | -0.517 | -0.1623 | No | ||
154 | LZTS2 | 2260440 | 17544 | -0.558 | -0.1607 | No | ||
155 | BRDT | 3940102 | 17613 | -0.600 | -0.1571 | No | ||
156 | DNAJB5 | 2900215 | 17628 | -0.611 | -0.1504 | No | ||
157 | MXD4 | 4810113 | 17661 | -0.632 | -0.1445 | No | ||
158 | BCAS3 | 4050647 | 17690 | -0.653 | -0.1381 | No | ||
159 | HOXA7 | 5910152 | 17724 | -0.670 | -0.1317 | No | ||
160 | PRKCH | 5720079 | 17758 | -0.689 | -0.1251 | No | ||
161 | KBTBD2 | 2320014 | 18048 | -0.935 | -0.1295 | No | ||
162 | ZFYVE26 | 6860152 | 18188 | -1.106 | -0.1236 | No | ||
163 | NOTCH1 | 3390114 | 18225 | -1.164 | -0.1114 | No | ||
164 | ATF7IP | 2690176 6770021 | 18306 | -1.342 | -0.0995 | No | ||
165 | EPC1 | 1570050 5290095 6900193 | 18379 | -1.571 | -0.0843 | No | ||
166 | HBP1 | 2510102 3130010 4210619 | 18447 | -1.783 | -0.0663 | No | ||
167 | NIT1 | 1230338 3940671 | 18488 | -2.027 | -0.0438 | No | ||
168 | ISGF3G | 3190131 7100142 | 18490 | -2.051 | -0.0190 | No | ||
169 | CDK5R1 | 3870161 | 18498 | -2.123 | 0.0064 | No |