Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | V$GFI1_01 |
Enrichment Score (ES) | -0.5967353 |
Normalized Enrichment Score (NES) | -1.5471243 |
Nominal p-value | 0.0028571428 |
FDR q-value | 0.17508633 |
FWER p-Value | 0.562 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | SFRS2 | 50707 380593 | 63 | 3.079 | 0.0549 | No | ||
2 | MBNL1 | 2640762 7100048 | 713 | 0.914 | 0.0370 | No | ||
3 | ABCF2 | 630040 3140035 6450601 | 718 | 0.910 | 0.0541 | No | ||
4 | ATP5G2 | 840068 | 759 | 0.874 | 0.0685 | No | ||
5 | SREBF2 | 3390692 | 819 | 0.828 | 0.0810 | No | ||
6 | CSAD | 770215 | 827 | 0.826 | 0.0963 | No | ||
7 | STMN1 | 1990717 | 1289 | 0.561 | 0.0819 | No | ||
8 | MCTS1 | 6130133 | 1588 | 0.441 | 0.0741 | No | ||
9 | HMGA1 | 6580408 | 1592 | 0.440 | 0.0823 | No | ||
10 | USP5 | 4850017 | 1672 | 0.412 | 0.0858 | No | ||
11 | SERTAD4 | 130593 | 1850 | 0.359 | 0.0830 | No | ||
12 | MYO1C | 3190398 | 1906 | 0.343 | 0.0865 | No | ||
13 | EXOC7 | 3060037 | 1919 | 0.340 | 0.0923 | No | ||
14 | TMPRSS2 | 2970279 | 2056 | 0.304 | 0.0907 | No | ||
15 | TLK1 | 7100605 | 2300 | 0.243 | 0.0821 | No | ||
16 | TCF4 | 520021 | 2397 | 0.223 | 0.0811 | No | ||
17 | PPARGC1B | 3290114 | 2856 | 0.146 | 0.0590 | No | ||
18 | CAMK2D | 2370685 | 2879 | 0.142 | 0.0605 | No | ||
19 | MYH10 | 2640673 | 2923 | 0.136 | 0.0607 | No | ||
20 | TPBG | 630161 | 2956 | 0.133 | 0.0615 | No | ||
21 | XPO5 | 2850286 | 2966 | 0.132 | 0.0635 | No | ||
22 | PDC | 3140400 3780184 | 3193 | 0.108 | 0.0533 | No | ||
23 | YWHAE | 5310435 | 3213 | 0.106 | 0.0543 | No | ||
24 | PPP2R2A | 2900014 5700575 | 3231 | 0.104 | 0.0553 | No | ||
25 | ETS1 | 5270278 6450717 6620465 | 3268 | 0.100 | 0.0553 | No | ||
26 | TRIM23 | 580168 6510672 | 3286 | 0.099 | 0.0562 | No | ||
27 | AVP | 2100113 | 3308 | 0.097 | 0.0569 | No | ||
28 | PRKAG1 | 6450091 | 3321 | 0.096 | 0.0581 | No | ||
29 | TCF12 | 3610324 7000156 | 3512 | 0.081 | 0.0493 | No | ||
30 | SLC4A7 | 2370056 | 3593 | 0.076 | 0.0464 | No | ||
31 | CDH13 | 5130368 5340114 | 3843 | 0.061 | 0.0341 | No | ||
32 | CNKSR1 | 730528 3390672 | 3844 | 0.061 | 0.0352 | No | ||
33 | CACNB2 | 1500095 7330707 | 3848 | 0.061 | 0.0362 | No | ||
34 | CNTN6 | 2630711 | 3872 | 0.060 | 0.0361 | No | ||
35 | SLC25A18 | 4540047 | 3913 | 0.058 | 0.0350 | No | ||
36 | RPS6KB1 | 1450427 5080110 6200563 | 3919 | 0.057 | 0.0359 | No | ||
37 | SOX9 | 5720681 | 4167 | 0.047 | 0.0234 | No | ||
38 | NR2F2 | 3170609 3310577 | 4398 | 0.040 | 0.0116 | No | ||
39 | LUZP1 | 940075 4280458 6180070 | 4507 | 0.036 | 0.0065 | No | ||
40 | PRIMA1 | 1500673 6760671 | 4508 | 0.036 | 0.0071 | No | ||
41 | PDE4D | 2470528 6660014 | 4558 | 0.035 | 0.0051 | No | ||
42 | ICAM4 | 6770053 | 4698 | 0.031 | -0.0018 | No | ||
43 | HOXA3 | 3610632 6020358 | 4725 | 0.031 | -0.0026 | No | ||
44 | MTMR4 | 4540524 | 4916 | 0.027 | -0.0124 | No | ||
45 | NCAM1 | 3140026 | 5032 | 0.025 | -0.0182 | No | ||
46 | JPH4 | 780020 | 5261 | 0.022 | -0.0302 | No | ||
47 | ICAM5 | 2350647 | 5305 | 0.021 | -0.0321 | No | ||
48 | PPARGC1A | 4670040 | 5467 | 0.019 | -0.0405 | No | ||
49 | ITGA10 | 6330438 | 5477 | 0.019 | -0.0406 | No | ||
50 | ANGPT1 | 3990368 5130288 6770035 | 5577 | 0.018 | -0.0456 | No | ||
51 | FOXP2 | 3520561 4150372 4760524 | 5637 | 0.018 | -0.0485 | No | ||
52 | PEA15 | 4590685 | 5661 | 0.018 | -0.0494 | No | ||
53 | GAS2 | 1340082 | 5683 | 0.017 | -0.0502 | No | ||
54 | OTP | 2630070 | 5767 | 0.017 | -0.0544 | No | ||
55 | RORA | 380164 5220215 | 5777 | 0.016 | -0.0546 | No | ||
56 | BAI3 | 940692 | 5943 | 0.015 | -0.0632 | No | ||
57 | ZFPM2 | 460072 | 5951 | 0.015 | -0.0633 | No | ||
58 | HOXC8 | 6220050 | 5955 | 0.015 | -0.0632 | No | ||
59 | MAP2K7 | 2260086 | 5971 | 0.015 | -0.0637 | No | ||
60 | PI15 | 3840133 | 6088 | 0.014 | -0.0698 | No | ||
61 | NFIA | 2760129 5860278 | 6211 | 0.013 | -0.0761 | No | ||
62 | HOXA9 | 610494 4730040 5130601 | 6215 | 0.013 | -0.0760 | No | ||
63 | GPR17 | 5890671 | 6295 | 0.013 | -0.0801 | No | ||
64 | HOXD11 | 2260242 | 6305 | 0.013 | -0.0803 | No | ||
65 | ZIC1 | 670113 | 6324 | 0.013 | -0.0811 | No | ||
66 | DDR2 | 7050273 | 6525 | 0.011 | -0.0917 | No | ||
67 | DCX | 130075 5360025 7050673 | 6737 | 0.010 | -0.1030 | No | ||
68 | CGN | 5890139 6370167 6400537 | 6781 | 0.010 | -0.1051 | No | ||
69 | ASB4 | 2100064 3060059 | 6863 | 0.010 | -0.1093 | No | ||
70 | ZIC3 | 380020 | 6897 | 0.009 | -0.1109 | No | ||
71 | HOXB8 | 3710450 | 6909 | 0.009 | -0.1114 | No | ||
72 | TBR1 | 5130053 | 6952 | 0.009 | -0.1135 | No | ||
73 | HIST1H1E | 6980706 | 7116 | 0.008 | -0.1222 | No | ||
74 | KLF15 | 4230164 | 7123 | 0.008 | -0.1223 | No | ||
75 | MEF2C | 670025 780338 | 7171 | 0.008 | -0.1247 | No | ||
76 | CDH6 | 4730541 | 7480 | 0.007 | -0.1413 | No | ||
77 | NGEF | 3190538 | 7482 | 0.007 | -0.1412 | No | ||
78 | PBX1 | 6660301 | 7635 | 0.007 | -0.1493 | No | ||
79 | GPR20 | 6620601 | 7698 | 0.006 | -0.1526 | No | ||
80 | BNC2 | 4810603 | 7836 | 0.006 | -0.1599 | No | ||
81 | SP8 | 4060576 | 7993 | 0.005 | -0.1683 | No | ||
82 | C1QTNF7 | 2970619 | 8031 | 0.005 | -0.1702 | No | ||
83 | CACNG3 | 520093 | 8072 | 0.005 | -0.1723 | No | ||
84 | HOXC4 | 1940193 | 8098 | 0.005 | -0.1735 | No | ||
85 | SH3BGRL2 | 1780239 | 8105 | 0.005 | -0.1738 | No | ||
86 | HOXA10 | 6110397 7100458 | 8235 | 0.004 | -0.1807 | No | ||
87 | PROCR | 4920687 | 8300 | 0.004 | -0.1841 | No | ||
88 | EBF2 | 940324 | 8358 | 0.004 | -0.1871 | No | ||
89 | KLF12 | 1660095 4810288 5340546 6520286 | 8475 | 0.004 | -0.1933 | No | ||
90 | ITSN1 | 2640577 | 8599 | 0.003 | -0.1999 | No | ||
91 | CLMN | 1340446 1660433 2940670 | 8638 | 0.003 | -0.2019 | No | ||
92 | HOXD10 | 6100039 | 8737 | 0.003 | -0.2072 | No | ||
93 | DSCR1L1 | 940438 | 8803 | 0.003 | -0.2107 | No | ||
94 | PCDH8 | 2360047 4200452 | 8829 | 0.003 | -0.2120 | No | ||
95 | PLCD4 | 6450040 | 8912 | 0.003 | -0.2164 | No | ||
96 | DEPDC2 | 5220102 | 9068 | 0.002 | -0.2247 | No | ||
97 | TFEC | 1170722 | 9435 | 0.001 | -0.2446 | No | ||
98 | CALN1 | 3610722 | 9683 | 0.000 | -0.2580 | No | ||
99 | TFB1M | 2190110 | 9833 | -0.000 | -0.2661 | No | ||
100 | PURA | 3870156 | 9881 | -0.000 | -0.2686 | No | ||
101 | HOXB3 | 520292 | 9888 | -0.000 | -0.2689 | No | ||
102 | HIST1H1T | 130632 | 9975 | -0.001 | -0.2736 | No | ||
103 | HOXB6 | 4210739 | 10097 | -0.001 | -0.2801 | No | ||
104 | DSPP | 5890403 | 10126 | -0.001 | -0.2816 | No | ||
105 | SOX15 | 2470603 | 10141 | -0.001 | -0.2824 | No | ||
106 | NRXN3 | 1400546 3360471 | 10155 | -0.001 | -0.2831 | No | ||
107 | GPRC5D | 4760021 | 10208 | -0.001 | -0.2859 | No | ||
108 | GRPR | 6020170 | 10271 | -0.001 | -0.2892 | No | ||
109 | PHF8 | 70722 | 10351 | -0.002 | -0.2935 | No | ||
110 | PTHLH | 5290739 | 10686 | -0.002 | -0.3115 | No | ||
111 | SGK2 | 1850070 | 10708 | -0.003 | -0.3126 | No | ||
112 | CDON | 540204 | 11026 | -0.004 | -0.3298 | No | ||
113 | BMP4 | 380113 | 11085 | -0.004 | -0.3329 | No | ||
114 | SLC26A3 | 380750 | 11197 | -0.004 | -0.3388 | No | ||
115 | GFRA3 | 6510609 | 11207 | -0.004 | -0.3392 | No | ||
116 | CHRM1 | 4280619 | 11231 | -0.004 | -0.3404 | No | ||
117 | TSGA10 | 450594 3130435 4920093 | 11342 | -0.005 | -0.3463 | No | ||
118 | PHYHIP | 1170377 | 11383 | -0.005 | -0.3483 | No | ||
119 | MSR1 | 940538 | 11469 | -0.005 | -0.3529 | No | ||
120 | NKX2-8 | 50022 | 11680 | -0.006 | -0.3641 | No | ||
121 | RKHD3 | 6180471 | 11690 | -0.006 | -0.3645 | No | ||
122 | EDN1 | 1770047 | 11775 | -0.006 | -0.3690 | No | ||
123 | BDNF | 2940128 3520368 | 11795 | -0.006 | -0.3699 | No | ||
124 | POU3F1 | 3710022 | 11951 | -0.007 | -0.3782 | No | ||
125 | HOXA6 | 2340333 | 11974 | -0.007 | -0.3792 | No | ||
126 | TLR1 | 1410524 | 12168 | -0.008 | -0.3895 | No | ||
127 | NEXN | 1240017 5290047 | 12273 | -0.008 | -0.3950 | No | ||
128 | ELAVL4 | 50735 3360086 5220167 | 12316 | -0.009 | -0.3971 | No | ||
129 | CRYZL1 | 730022 2320044 | 12423 | -0.009 | -0.4027 | No | ||
130 | DPF3 | 2650128 2970168 | 12571 | -0.010 | -0.4105 | No | ||
131 | GREM1 | 3940180 | 12578 | -0.010 | -0.4107 | No | ||
132 | SPAG7 | 4560524 | 12631 | -0.010 | -0.4133 | No | ||
133 | MEIS1 | 1400575 | 12634 | -0.010 | -0.4132 | No | ||
134 | CREB5 | 2320368 | 12683 | -0.010 | -0.4156 | No | ||
135 | CPEB3 | 3940164 | 12861 | -0.011 | -0.4250 | No | ||
136 | MRGPRF | 4780746 | 13151 | -0.013 | -0.4404 | No | ||
137 | DSG3 | 3940014 | 13184 | -0.014 | -0.4419 | No | ||
138 | SOX5 | 2370576 2900167 3190128 5050528 | 13250 | -0.014 | -0.4452 | No | ||
139 | DNAJB4 | 380195 2760372 3940735 | 13273 | -0.014 | -0.4461 | No | ||
140 | GRK6 | 1500053 | 13347 | -0.015 | -0.4498 | No | ||
141 | SOSTDC1 | 6760017 | 13548 | -0.017 | -0.4603 | No | ||
142 | RARB | 430139 1410138 | 13554 | -0.017 | -0.4603 | No | ||
143 | PHACTR3 | 3850435 5900445 | 13813 | -0.020 | -0.4739 | No | ||
144 | TRDN | 1580411 | 13879 | -0.021 | -0.4770 | No | ||
145 | IRX3 | 4200112 | 13886 | -0.021 | -0.4769 | No | ||
146 | CTLA4 | 6590537 | 14189 | -0.026 | -0.4928 | No | ||
147 | CDX2 | 3850349 | 14232 | -0.027 | -0.4946 | No | ||
148 | RAB6B | 5860121 | 14477 | -0.032 | -0.5072 | No | ||
149 | JMJD1C | 940575 2120025 | 14762 | -0.040 | -0.5219 | No | ||
150 | BCL9 | 7100112 | 14909 | -0.047 | -0.5289 | No | ||
151 | TCF1 | 5390022 | 15147 | -0.061 | -0.5406 | No | ||
152 | TRAF4 | 3060041 4920528 6980286 | 15313 | -0.073 | -0.5482 | No | ||
153 | LAMA3 | 1190131 5290239 | 15423 | -0.082 | -0.5526 | No | ||
154 | ELMO3 | 110372 2640019 | 15459 | -0.085 | -0.5528 | No | ||
155 | BPGM | 5080520 | 15509 | -0.089 | -0.5538 | No | ||
156 | ATF2 | 2260348 2480441 | 15845 | -0.126 | -0.5696 | No | ||
157 | HIVEP3 | 3990551 | 15947 | -0.136 | -0.5725 | No | ||
158 | PDLIM1 | 450100 | 15988 | -0.142 | -0.5720 | No | ||
159 | ZIC4 | 1500082 | 16025 | -0.146 | -0.5712 | No | ||
160 | PANK1 | 670091 6220605 | 16107 | -0.159 | -0.5726 | No | ||
161 | BRUNOL4 | 4490452 5080451 | 16157 | -0.165 | -0.5721 | No | ||
162 | RKHD1 | 6860577 | 16222 | -0.174 | -0.5723 | No | ||
163 | TOP1 | 770471 4060632 6650324 | 16236 | -0.176 | -0.5696 | No | ||
164 | CREM | 840156 6380438 6660041 6660168 | 16320 | -0.189 | -0.5705 | No | ||
165 | ARHGEF2 | 3360577 | 16369 | -0.198 | -0.5694 | No | ||
166 | MAP4K3 | 5390551 | 16426 | -0.209 | -0.5685 | No | ||
167 | MAP2K5 | 2030440 | 16563 | -0.240 | -0.5713 | No | ||
168 | ADD3 | 4150739 5390600 | 16993 | -0.347 | -0.5880 | No | ||
169 | HNRPA0 | 2680048 | 17155 | -0.401 | -0.5891 | Yes | ||
170 | PTEN | 3390064 | 17161 | -0.403 | -0.5818 | Yes | ||
171 | BCL9L | 6940053 | 17235 | -0.427 | -0.5776 | Yes | ||
172 | WDR23 | 2030372 | 17322 | -0.463 | -0.5735 | Yes | ||
173 | POLH | 2690528 | 17472 | -0.529 | -0.5716 | Yes | ||
174 | PREP | 6220292 | 17518 | -0.548 | -0.5636 | Yes | ||
175 | SOX4 | 2260091 | 17671 | -0.637 | -0.5598 | Yes | ||
176 | HOXA7 | 5910152 | 17724 | -0.670 | -0.5499 | Yes | ||
177 | GABARAP | 1450286 | 17808 | -0.719 | -0.5408 | Yes | ||
178 | TCTA | 2680687 | 17919 | -0.800 | -0.5316 | Yes | ||
179 | BRD2 | 1450300 5340484 6100605 | 17962 | -0.833 | -0.5181 | Yes | ||
180 | IRF2BP1 | 3170019 | 18019 | -0.891 | -0.5042 | Yes | ||
181 | GADD45A | 2900717 | 18078 | -0.966 | -0.4891 | Yes | ||
182 | AGPAT4 | 6040079 | 18093 | -0.980 | -0.4712 | Yes | ||
183 | MAP3K3 | 610685 | 18187 | -1.104 | -0.4554 | Yes | ||
184 | EVA1 | 5690538 | 18347 | -1.472 | -0.4361 | Yes | ||
185 | HSD11B1 | 450066 5550408 | 18355 | -1.488 | -0.4082 | Yes | ||
186 | MAP4K2 | 4200037 | 18402 | -1.668 | -0.3791 | Yes | ||
187 | HBP1 | 2510102 3130010 4210619 | 18447 | -1.783 | -0.3477 | Yes | ||
188 | CCR7 | 2060687 | 18570 | -2.914 | -0.2991 | Yes | ||
189 | IL16 | 3850168 | 18571 | -2.923 | -0.2437 | Yes | ||
190 | BCL6 | 940100 | 18572 | -2.937 | -0.1880 | Yes | ||
191 | BTG1 | 4200735 6040131 6200133 | 18607 | -4.199 | -0.1102 | Yes | ||
192 | RHOA | 580142 5900131 5340450 | 18613 | -5.837 | 0.0002 | Yes |