Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
Upregulated in class | absentNotch |
GeneSet | V$E2F_Q3 |
Enrichment Score (ES) | 0.60090375 |
Normalized Enrichment Score (NES) | 1.4354615 |
Nominal p-value | 0.007788162 |
FDR q-value | 0.57958543 |
FWER p-Value | 0.997 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | SFRS2 | 50707 380593 | 63 | 3.079 | 0.0598 | Yes | ||
2 | HNRPA1 | 4670398 5050687 | 71 | 2.999 | 0.1210 | Yes | ||
3 | MCM6 | 60092 540181 6510110 | 96 | 2.628 | 0.1737 | Yes | ||
4 | TCP1 | 2450100 5130524 | 144 | 2.239 | 0.2171 | Yes | ||
5 | CDC6 | 4570296 5360600 | 211 | 1.867 | 0.2518 | Yes | ||
6 | MCM4 | 2760673 5420711 | 231 | 1.746 | 0.2867 | Yes | ||
7 | TFRC | 4050551 | 244 | 1.692 | 0.3208 | Yes | ||
8 | NCL | 2360463 4540279 | 407 | 1.334 | 0.3394 | Yes | ||
9 | E2F1 | 5360093 | 513 | 1.141 | 0.3571 | Yes | ||
10 | GCH1 | 670364 6550358 | 525 | 1.126 | 0.3796 | Yes | ||
11 | DLST | 2320722 | 634 | 1.002 | 0.3943 | Yes | ||
12 | SHMT1 | 5900132 | 641 | 0.994 | 0.4144 | Yes | ||
13 | APRIN | 2810050 | 692 | 0.931 | 0.4308 | Yes | ||
14 | ABCF2 | 630040 3140035 6450601 | 718 | 0.910 | 0.4481 | Yes | ||
15 | RBBP7 | 430113 450450 2370309 | 801 | 0.838 | 0.4609 | Yes | ||
16 | UNG | 3130110 6100364 | 872 | 0.798 | 0.4735 | Yes | ||
17 | NASP | 2260139 2940369 5130707 | 920 | 0.768 | 0.4867 | Yes | ||
18 | IMPDH2 | 5220138 | 950 | 0.750 | 0.5006 | Yes | ||
19 | RFC1 | 1190673 | 960 | 0.743 | 0.5153 | Yes | ||
20 | PIAS1 | 5340301 | 1110 | 0.650 | 0.5206 | Yes | ||
21 | ZCCHC8 | 2260332 2350487 | 1183 | 0.613 | 0.5293 | Yes | ||
22 | STMN1 | 1990717 | 1289 | 0.561 | 0.5352 | Yes | ||
23 | SLC25A3 | 670112 | 1327 | 0.546 | 0.5444 | Yes | ||
24 | LIG1 | 1980438 4540112 5570609 | 1347 | 0.535 | 0.5543 | Yes | ||
25 | OLFML3 | 7100463 | 1428 | 0.502 | 0.5603 | Yes | ||
26 | MCM3 | 5570068 | 1578 | 0.444 | 0.5613 | Yes | ||
27 | PPP1R8 | 6290292 | 1657 | 0.418 | 0.5657 | Yes | ||
28 | HIST1H2BK | 6130433 | 1728 | 0.400 | 0.5701 | Yes | ||
29 | SLC38A1 | 520465 | 1801 | 0.374 | 0.5739 | Yes | ||
30 | CDC25A | 3800184 | 1889 | 0.350 | 0.5764 | Yes | ||
31 | PRPS1 | 6350129 | 1900 | 0.346 | 0.5829 | Yes | ||
32 | AP4M1 | 70609 3440128 | 1912 | 0.342 | 0.5894 | Yes | ||
33 | HMGN2 | 3140091 | 1962 | 0.326 | 0.5934 | Yes | ||
34 | KPNB1 | 1690138 | 2115 | 0.286 | 0.5910 | Yes | ||
35 | POLA2 | 940519 | 2129 | 0.283 | 0.5961 | Yes | ||
36 | RBBP4 | 6650528 | 2148 | 0.279 | 0.6009 | Yes | ||
37 | LASP1 | 1690528 2190341 6420341 | 2364 | 0.230 | 0.5940 | No | ||
38 | DNAJC11 | 360465 3390215 | 2477 | 0.209 | 0.5922 | No | ||
39 | MCM2 | 5050139 | 2513 | 0.201 | 0.5944 | No | ||
40 | CDCA7 | 3060097 | 2549 | 0.194 | 0.5965 | No | ||
41 | BAT3 | 1990594 | 2637 | 0.179 | 0.5955 | No | ||
42 | TBX6 | 4730139 6840647 | 2682 | 0.173 | 0.5966 | No | ||
43 | MCM7 | 3290292 5220056 | 2697 | 0.169 | 0.5993 | No | ||
44 | GMNN | 2630148 | 2861 | 0.145 | 0.5935 | No | ||
45 | EZH2 | 6130605 6380524 | 2904 | 0.138 | 0.5940 | No | ||
46 | MRPL18 | 6560341 | 3038 | 0.124 | 0.5894 | No | ||
47 | KCNA1 | 2030594 | 3041 | 0.124 | 0.5918 | No | ||
48 | PHF15 | 6550066 6860673 | 3065 | 0.122 | 0.5931 | No | ||
49 | H2AFZ | 1470168 | 3127 | 0.115 | 0.5922 | No | ||
50 | ADAMTS2 | 2650025 6370133 6840670 | 3292 | 0.098 | 0.5853 | No | ||
51 | EPHB2 | 1090288 1410377 2100541 | 3504 | 0.082 | 0.5755 | No | ||
52 | KLF4 | 1850022 3830239 5570750 | 3653 | 0.072 | 0.5690 | No | ||
53 | SSBP3 | 870717 1050377 7040551 | 3782 | 0.065 | 0.5634 | No | ||
54 | E2F3 | 50162 460180 | 3800 | 0.064 | 0.5638 | No | ||
55 | PRKDC | 1400072 4230541 | 3859 | 0.060 | 0.5619 | No | ||
56 | CNOT3 | 130519 4480292 1990609 | 4233 | 0.045 | 0.5426 | No | ||
57 | SNPH | 2680484 | 4242 | 0.044 | 0.5431 | No | ||
58 | PAQR4 | 730736 | 4275 | 0.043 | 0.5423 | No | ||
59 | UFD1L | 870020 | 4293 | 0.043 | 0.5422 | No | ||
60 | TBX3 | 2570672 | 4443 | 0.038 | 0.5349 | No | ||
61 | CPNE5 | 6380673 | 4457 | 0.038 | 0.5350 | No | ||
62 | RHD | 4050168 | 4459 | 0.038 | 0.5357 | No | ||
63 | STAG2 | 4540132 | 4548 | 0.035 | 0.5317 | No | ||
64 | BARHL1 | 4210113 | 4661 | 0.032 | 0.5263 | No | ||
65 | NDUFA11 | 3780333 | 4675 | 0.032 | 0.5262 | No | ||
66 | CTCF | 5340017 | 4877 | 0.028 | 0.5159 | No | ||
67 | TRIM47 | 5080717 | 4999 | 0.026 | 0.5099 | No | ||
68 | ADCY8 | 6760519 | 5456 | 0.019 | 0.4856 | No | ||
69 | SFRS1 | 2360440 | 5619 | 0.018 | 0.4772 | No | ||
70 | HS6ST3 | 5910138 | 6160 | 0.014 | 0.4482 | No | ||
71 | PCSK1 | 2350148 | 6251 | 0.013 | 0.4436 | No | ||
72 | JPH1 | 610739 | 6272 | 0.013 | 0.4428 | No | ||
73 | SLC6A4 | 2230372 | 6511 | 0.011 | 0.4302 | No | ||
74 | KCND2 | 1170128 2100112 | 6883 | 0.009 | 0.4103 | No | ||
75 | ARHGAP6 | 2060121 | 6945 | 0.009 | 0.4072 | No | ||
76 | FMO4 | 360735 | 7640 | 0.007 | 0.3697 | No | ||
77 | WEE1 | 3390070 | 7696 | 0.006 | 0.3669 | No | ||
78 | SMAD6 | 870504 | 7715 | 0.006 | 0.3660 | No | ||
79 | ASCL1 | 6650100 | 7766 | 0.006 | 0.3634 | No | ||
80 | PODN | 3710068 | 7878 | 0.006 | 0.3575 | No | ||
81 | HNRPD | 4120021 | 7933 | 0.005 | 0.3547 | No | ||
82 | ATRX | 2340039 3610132 4210373 | 7963 | 0.005 | 0.3533 | No | ||
83 | ERBB2IP | 580253 1090672 | 8001 | 0.005 | 0.3514 | No | ||
84 | GRIK2 | 4610164 | 8115 | 0.005 | 0.3454 | No | ||
85 | PAPOLG | 2470400 | 8123 | 0.005 | 0.3451 | No | ||
86 | STK35 | 2360121 | 8338 | 0.004 | 0.3336 | No | ||
87 | POLE2 | 6110041 | 8700 | 0.003 | 0.3141 | No | ||
88 | HTF9C | 3190048 4120132 | 8807 | 0.003 | 0.3084 | No | ||
89 | AP1S2 | 780279 4280707 | 9240 | 0.002 | 0.2851 | No | ||
90 | NPR3 | 1580239 | 9259 | 0.002 | 0.2841 | No | ||
91 | NRP2 | 4070400 5860041 6650446 | 9922 | -0.000 | 0.2483 | No | ||
92 | TOPBP1 | 6020333 | 10056 | -0.001 | 0.2411 | No | ||
93 | SEZ6 | 3450722 | 10151 | -0.001 | 0.2360 | No | ||
94 | HIST1H1D | 3440446 | 10299 | -0.001 | 0.2281 | No | ||
95 | DMD | 1740041 3990332 | 11250 | -0.004 | 0.1768 | No | ||
96 | FBXO5 | 2630551 | 11280 | -0.004 | 0.1753 | No | ||
97 | IPO7 | 2190746 | 11285 | -0.004 | 0.1751 | No | ||
98 | NUP153 | 7000452 | 11299 | -0.005 | 0.1745 | No | ||
99 | ATAD2 | 870242 2260687 | 11466 | -0.005 | 0.1657 | No | ||
100 | RAD51 | 6110450 6980280 | 11516 | -0.005 | 0.1631 | No | ||
101 | PEG3 | 3710020 | 11767 | -0.006 | 0.1497 | No | ||
102 | EPHB1 | 4610056 | 11784 | -0.006 | 0.1490 | No | ||
103 | TREX2 | 4920707 | 12069 | -0.007 | 0.1337 | No | ||
104 | CASP8AP2 | 5910593 | 12474 | -0.009 | 0.1121 | No | ||
105 | MEIS1 | 1400575 | 12634 | -0.010 | 0.1037 | No | ||
106 | ONECUT1 | 6450136 | 12669 | -0.010 | 0.1020 | No | ||
107 | SEMA5A | 6200110 6520435 | 13123 | -0.013 | 0.0778 | No | ||
108 | UXT | 110019 5080066 | 13156 | -0.013 | 0.0763 | No | ||
109 | CACNA1G | 3060161 4810706 5550722 | 13288 | -0.014 | 0.0695 | No | ||
110 | LHX5 | 2350097 | 13370 | -0.015 | 0.0654 | No | ||
111 | CBX5 | 3830072 6290167 | 13476 | -0.016 | 0.0601 | No | ||
112 | CLTA | 450010 | 13536 | -0.017 | 0.0572 | No | ||
113 | SALL1 | 5420020 7050195 | 13700 | -0.019 | 0.0488 | No | ||
114 | NOL4 | 5050446 5360519 | 14046 | -0.024 | 0.0306 | No | ||
115 | ARID4A | 520156 1050707 | 14162 | -0.026 | 0.0249 | No | ||
116 | MCM8 | 6130743 | 14235 | -0.027 | 0.0216 | No | ||
117 | ATE1 | 290491 6940722 | 14363 | -0.029 | 0.0153 | No | ||
118 | DPYSL2 | 2100427 3130112 5700324 | 14586 | -0.035 | 0.0040 | No | ||
119 | MDGA1 | 1170139 | 14696 | -0.038 | -0.0012 | No | ||
120 | HIST1H2AH | 3710333 | 15047 | -0.055 | -0.0190 | No | ||
121 | PVRL1 | 2570167 5220519 5890500 3190309 | 15059 | -0.055 | -0.0184 | No | ||
122 | INSM1 | 3450671 | 15151 | -0.061 | -0.0221 | No | ||
123 | E2F7 | 4200056 | 15660 | -0.106 | -0.0474 | No | ||
124 | DDB2 | 3520341 4610168 4850184 4920717 | 15677 | -0.108 | -0.0461 | No | ||
125 | CTDSP1 | 6650215 6940731 | 15763 | -0.117 | -0.0483 | No | ||
126 | KLF5 | 3840348 | 15876 | -0.129 | -0.0517 | No | ||
127 | DNMT1 | 2260097 | 15974 | -0.140 | -0.0541 | No | ||
128 | ING3 | 110438 2060390 | 16172 | -0.167 | -0.0613 | No | ||
129 | PCNA | 940754 | 16216 | -0.173 | -0.0601 | No | ||
130 | PLK4 | 430162 5720110 | 16348 | -0.194 | -0.0632 | No | ||
131 | USP1 | 2760541 5690438 6220673 | 16451 | -0.214 | -0.0643 | No | ||
132 | MAT2A | 4070026 4730079 6020280 | 16466 | -0.218 | -0.0606 | No | ||
133 | PCSK4 | 130687 670711 3170075 6400411 | 16490 | -0.222 | -0.0573 | No | ||
134 | ORC1L | 2370328 6110390 | 16498 | -0.223 | -0.0531 | No | ||
135 | FLI1 | 3990142 | 16745 | -0.280 | -0.0606 | No | ||
136 | CDC45L | 70537 3130114 | 17001 | -0.348 | -0.0673 | No | ||
137 | PPP1CC | 6380300 2510647 | 17032 | -0.357 | -0.0616 | No | ||
138 | SLC25A14 | 4760180 | 17166 | -0.403 | -0.0605 | No | ||
139 | PIM1 | 630047 | 17249 | -0.433 | -0.0561 | No | ||
140 | RANBP1 | 430215 1090180 | 17406 | -0.499 | -0.0543 | No | ||
141 | PHF12 | 870400 3130687 | 17447 | -0.516 | -0.0458 | No | ||
142 | MAZ | 3360121 6940750 | 17577 | -0.577 | -0.0410 | No | ||
143 | PHF13 | 450435 | 17710 | -0.663 | -0.0345 | No | ||
144 | RAB11B | 3990609 | 17752 | -0.685 | -0.0227 | No | ||
145 | SYT11 | 630433 | 17765 | -0.693 | -0.0091 | No | ||
146 | MXD3 | 6220014 | 17993 | -0.868 | -0.0036 | No | ||
147 | DCK | 6900411 | 18454 | -1.815 | 0.0088 | No |