Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
| Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | TCRPATHWAY |
| Enrichment Score (ES) | -0.7429944 |
| Normalized Enrichment Score (NES) | -1.558074 |
| Nominal p-value | 0.0073710075 |
| FDR q-value | 0.3234431 |
| FWER p-Value | 0.979 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PPP3CB | 6020156 | 1128 | 0.643 | -0.0293 | No | ||
| 2 | GRB2 | 6650398 | 1188 | 0.612 | -0.0025 | No | ||
| 3 | MAP2K4 | 5130133 | 1821 | 0.367 | -0.0186 | No | ||
| 4 | RAC1 | 4810687 | 1942 | 0.331 | -0.0089 | No | ||
| 5 | NFKB1 | 5420358 | 2177 | 0.270 | -0.0083 | No | ||
| 6 | RAF1 | 1770600 | 2375 | 0.227 | -0.0078 | No | ||
| 7 | MAPK8 | 2640195 | 3135 | 0.114 | -0.0430 | No | ||
| 8 | HRAS | 1980551 | 4798 | 0.029 | -0.1311 | No | ||
| 9 | PPP3CA | 4760332 6760092 | 5029 | 0.025 | -0.1423 | No | ||
| 10 | PLCG1 | 6020369 | 5664 | 0.017 | -0.1755 | No | ||
| 11 | CALM1 | 380128 | 5743 | 0.017 | -0.1789 | No | ||
| 12 | NFATC4 | 2470735 | 6252 | 0.013 | -0.2056 | No | ||
| 13 | PIK3R1 | 4730671 | 7437 | 0.007 | -0.2690 | No | ||
| 14 | MAP2K1 | 840739 | 8060 | 0.005 | -0.3023 | No | ||
| 15 | CALM2 | 6620463 | 8534 | 0.004 | -0.3275 | No | ||
| 16 | NFATC2 | 70450 540097 | 9799 | 0.000 | -0.3956 | No | ||
| 17 | SOS1 | 7050338 | 11108 | -0.004 | -0.4658 | No | ||
| 18 | JUN | 840170 | 11404 | -0.005 | -0.4815 | No | ||
| 19 | SYT1 | 840364 | 12402 | -0.009 | -0.5347 | No | ||
| 20 | PIK3CA | 6220129 | 12684 | -0.010 | -0.5493 | No | ||
| 21 | SHC1 | 2900731 3170504 6520537 | 13907 | -0.021 | -0.6141 | No | ||
| 22 | PRKCA | 6400551 | 13942 | -0.022 | -0.6148 | No | ||
| 23 | FOS | 1850315 | 14022 | -0.023 | -0.6179 | No | ||
| 24 | NFATC1 | 510400 2320348 4050600 6180161 6290136 6620086 | 14962 | -0.050 | -0.6661 | No | ||
| 25 | FYN | 2100468 4760520 4850687 | 15761 | -0.116 | -0.7033 | No | ||
| 26 | ZAP70 | 1410494 2260504 | 16061 | -0.152 | -0.7120 | No | ||
| 27 | PPP3CC | 2450139 | 16238 | -0.177 | -0.7128 | No | ||
| 28 | PTPN7 | 3450110 | 16799 | -0.293 | -0.7287 | Yes | ||
| 29 | LAT | 3170025 | 16883 | -0.315 | -0.7177 | Yes | ||
| 30 | RASA1 | 1240315 | 16954 | -0.335 | -0.7051 | Yes | ||
| 31 | CALM3 | 3390288 | 17028 | -0.355 | -0.6917 | Yes | ||
| 32 | PRKCB1 | 870019 3130092 | 17100 | -0.384 | -0.6768 | Yes | ||
| 33 | NFKBIA | 1570152 | 17293 | -0.450 | -0.6651 | Yes | ||
| 34 | RELA | 3830075 | 17328 | -0.467 | -0.6441 | Yes | ||
| 35 | MAPK3 | 580161 4780035 | 17348 | -0.472 | -0.6220 | Yes | ||
| 36 | LCK | 3360142 | 17548 | -0.561 | -0.6053 | Yes | ||
| 37 | VAV1 | 6020487 | 17855 | -0.751 | -0.5851 | Yes | ||
| 38 | MAP3K1 | 5360347 | 18135 | -1.031 | -0.5497 | Yes | ||
| 39 | CD3E | 3800056 | 18269 | -1.267 | -0.4949 | Yes | ||
| 40 | CD3D | 2810739 | 18272 | -1.277 | -0.4326 | Yes | ||
| 41 | NFATC3 | 5050520 | 18471 | -1.928 | -0.3490 | Yes | ||
| 42 | CD3G | 2680288 | 18531 | -2.468 | -0.2315 | Yes | ||
| 43 | TRB@ | 3940292 | 18610 | -4.828 | 0.0003 | Yes |
