Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos |
| Phenotype | phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | HSA04330_NOTCH_SIGNALING_PATHWAY |
| Enrichment Score (ES) | -0.74731 |
| Normalized Enrichment Score (NES) | -1.5549397 |
| Nominal p-value | 0.011547344 |
| FDR q-value | 0.30981463 |
| FWER p-Value | 0.984 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | GCN5L2 | 2340609 | 821 | 0.827 | 0.0101 | No | ||
| 2 | DTX2 | 4210041 7000008 | 1748 | 0.394 | -0.0139 | No | ||
| 3 | HDAC2 | 4050433 | 2108 | 0.287 | -0.0144 | No | ||
| 4 | JAG2 | 1500341 | 2335 | 0.236 | -0.0111 | No | ||
| 5 | CREBBP | 5690035 7040050 | 3086 | 0.119 | -0.0437 | No | ||
| 6 | PSEN2 | 130382 | 3230 | 0.104 | -0.0446 | No | ||
| 7 | CTBP2 | 430309 3710079 | 3596 | 0.076 | -0.0592 | No | ||
| 8 | NOTCH4 | 2450040 6370707 | 3758 | 0.066 | -0.0635 | No | ||
| 9 | DTX4 | 4120433 | 4481 | 0.037 | -0.1000 | No | ||
| 10 | SNW1 | 4010736 | 4562 | 0.035 | -0.1020 | No | ||
| 11 | DLL3 | 4010093 | 5827 | 0.016 | -0.1690 | No | ||
| 12 | DLL4 | 6400403 | 6873 | 0.009 | -0.2246 | No | ||
| 13 | DLL1 | 1770377 | 7009 | 0.009 | -0.2313 | No | ||
| 14 | APH1A | 4060273 4670465 6450711 | 7934 | 0.005 | -0.2807 | No | ||
| 15 | DVL3 | 360156 5390075 | 8751 | 0.003 | -0.3244 | No | ||
| 16 | RBPJL | 5390019 | 9314 | 0.001 | -0.3546 | No | ||
| 17 | RBPJ | 2360164 5550136 5720402 | 9453 | 0.001 | -0.3619 | No | ||
| 18 | PCAF | 2230161 2570369 6550451 | 10437 | -0.002 | -0.4147 | No | ||
| 19 | MFNG | 1770242 4280348 | 11545 | -0.005 | -0.4740 | No | ||
| 20 | NCOR2 | 1980575 6550050 | 11835 | -0.006 | -0.4891 | No | ||
| 21 | JAG1 | 3440390 | 12186 | -0.008 | -0.5074 | No | ||
| 22 | NUMBL | 6130360 6200333 | 12783 | -0.011 | -0.5388 | No | ||
| 23 | NOTCH2 | 2570397 | 13506 | -0.016 | -0.5766 | No | ||
| 24 | CTBP1 | 3780315 | 13843 | -0.021 | -0.5933 | No | ||
| 25 | NUMB | 2450735 3800253 6350040 | 13969 | -0.022 | -0.5986 | No | ||
| 26 | HDAC1 | 2850670 | 14978 | -0.051 | -0.6495 | No | ||
| 27 | DVL2 | 6110162 | 15246 | -0.068 | -0.6594 | No | ||
| 28 | RFNG | 6290086 | 16048 | -0.149 | -0.6927 | No | ||
| 29 | LFNG | 5360711 | 16528 | -0.231 | -0.7033 | No | ||
| 30 | ADAM17 | 360292 | 17156 | -0.402 | -0.7108 | Yes | ||
| 31 | HES1 | 4810280 | 17836 | -0.736 | -0.6990 | Yes | ||
| 32 | DVL1 | 5900450 6510162 | 18007 | -0.877 | -0.6507 | Yes | ||
| 33 | DTX1 | 5900372 | 18067 | -0.956 | -0.5912 | Yes | ||
| 34 | NOTCH1 | 3390114 | 18225 | -1.164 | -0.5233 | Yes | ||
| 35 | NOTCH3 | 3060603 | 18226 | -1.164 | -0.4470 | Yes | ||
| 36 | NCSTN | 940601 6400594 | 18240 | -1.190 | -0.3697 | Yes | ||
| 37 | DTX3 | 1690458 | 18264 | -1.251 | -0.2889 | Yes | ||
| 38 | MAML1 | 2760008 | 18267 | -1.263 | -0.2062 | Yes | ||
| 39 | PTCRA | 6940142 | 18404 | -1.670 | -0.1040 | Yes | ||
| 40 | PSEN1 | 130403 2030647 6100603 | 18435 | -1.758 | 0.0097 | Yes |
