Details for gene set BRENTANI

Table: GSEA Results Summary

Dataset	Set_03_absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy.phenotype_absentNotch_versus_normalThy.cls #absentNotch_versus_normalThy_repos
Phenotype	phenotype_absentNotch_versus_normalThy.cls#absentNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	BRENTANI_SIGNALING
Enrichment Score (ES)	-0.6116679
Normalized Enrichment Score (NES)	-1.5589404
Nominal p-value	0.0
FDR q-value	0.35061792
FWER p-Value	0.977

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	MAP3K7IP1	2120095 5890452 6040167	121	2.379	0.0419	No
2	TNFSF13	2650170	784	0.851	0.0234	No
3	MAPK13	6760215	853	0.811	0.0362	No
4	AXL	1770095	1174	0.619	0.0315	No
5	STAT5A	2680458	1375	0.523	0.0313	No
6	GRB7	2100471	1477	0.484	0.0357	No
7	IL12RB1	2230338 5420053	1582	0.443	0.0391	No
8	MAP2K4	5130133	1821	0.367	0.0337	No
9	MAPK10	6110193	1857	0.358	0.0391	No
10	ITGB1	5080156 6270528	1874	0.353	0.0454	No
11	SMO	5340538 6350132	2069	0.301	0.0410	No
12	ITGA9	670180	2096	0.290	0.0455	No
13	MAPKAPK2	2850500	2120	0.284	0.0501	No
14	CXCL1	2690537	2144	0.280	0.0545	No
15	ITGB5	70129	2191	0.267	0.0575	No
16	IL10	2340685 2640541 2850403 6590286	2268	0.251	0.0585	No
17	JAG2	1500341	2335	0.236	0.0597	No
18	RAF1	1770600	2375	0.227	0.0622	No
19	TYRO3	3130193	2664	0.175	0.0502	No
20	BTK	3130044	2668	0.174	0.0536	No
21	MAP2K2	4590601	2672	0.174	0.0570	No
22	ABL1	1050593 2030050 4010114	3116	0.115	0.0353	No
23	YWHAE	5310435	3213	0.106	0.0322	No
24	CAMK4	1690091	3297	0.098	0.0297	No
25	NRAS	6900577	3584	0.077	0.0158	No
26	NOTCH4	2450040 6370707	3758	0.066	0.0078	No
27	TNFSF4	3940594	4091	0.050	-0.0092	No
28	IL1B	2640364	4117	0.049	-0.0096	No
29	MAPK1	3190193 6200253	4185	0.046	-0.0122	No
30	TANK	1090020 2060458 2370400	4226	0.045	-0.0135	No
31	BCR	2260020 4230180 6040195	4419	0.039	-0.0231	No
32	TNFRSF10B	940671 1500451 6550768 6900500	4600	0.034	-0.0322	No
33	ITGA3	4570427	4687	0.032	-0.0362	No
34	HRAS	1980551	4798	0.029	-0.0416	No
35	PTCH2	2900092	4818	0.029	-0.0420	No
36	TNF	6650603	4887	0.028	-0.0451	No
37	ERG	50154 1770739	5000	0.026	-0.0507	No
38	MCC	620750	5028	0.025	-0.0516	No
39	CXCL2	610398	5151	0.023	-0.0578	No
40	IL13	7040021	5371	0.021	-0.0692	No
41	IFNB1	1400142	5487	0.019	-0.0750	No
42	ARHGEF16	3990372	5658	0.018	-0.0839	No
43	TNFRSF1B	3990035 5860372	5722	0.017	-0.0870	No
44	CALM1	380128	5743	0.017	-0.0877	No
45	ITGA4	2470739	5778	0.016	-0.0892	No
46	MAP2K7	2260086	5971	0.015	-0.0993	No
47	INHA	6100102	6190	0.013	-0.1109	No
48	WNT4	4150619	6493	0.012	-0.1270	No
49	SUFU	6650181	6619	0.011	-0.1336	No
50	TTK	3800129	6736	0.010	-0.1396	No
51	ARHGAP6	2060121	6945	0.009	-0.1507	No
52	MPL	2360253	7295	0.008	-0.1695	No
53	MAP3K4	5720041	7343	0.008	-0.1719	No
54	IGFBP3	2370500	7467	0.007	-0.1784	No
55	MAPK11	130452 3120440 3610465	7589	0.007	-0.1848	No
56	AKT1	5290746	7797	0.006	-0.1959	No
57	ITGA7	1230739	7800	0.006	-0.1959	No
58	MAP2K1	840739	8060	0.005	-0.2098	No
59	RAP1A	1090025	8182	0.005	-0.2163	No
60	ARHGEF12	3990195	8868	0.003	-0.2534	No
61	SKIL	1090364	8954	0.002	-0.2579	No
62	WNT1	4780148	8974	0.002	-0.2589	No
63	ROS1	1090019	9403	0.001	-0.2821	No
64	ITGAM	1190373	9446	0.001	-0.2843	No
65	MAS1	2650600	9500	0.001	-0.2872	No
66	GRB14	510035 3060369	9508	0.001	-0.2876	No
67	ITGAV	2340020	9652	0.000	-0.2953	No
68	RAN	2260446 4590647	9782	0.000	-0.3023	No
69	MAPKAPK5	2510601	9793	0.000	-0.3028	No
70	MAP3K12	2470373 6420162	9831	-0.000	-0.3048	No
71	WNT5A	840685 3120152	10055	-0.001	-0.3169	No
72	IGFBP1	5720435	10169	-0.001	-0.3230	No
73	MUSK	1190113	10173	-0.001	-0.3231	No
74	MAPK7	5670079 6100128	10297	-0.001	-0.3298	No
75	MAPK12	450022 1340717 7050484	10517	-0.002	-0.3416	No
76	ABL2	580021	10531	-0.002	-0.3423	No
77	ITGAX	6130524	11003	-0.004	-0.3677	No
78	SOS1	7050338	11108	-0.004	-0.3733	No
79	MAPK4	870142	11473	-0.005	-0.3929	No
80	WNT2	4610020	11616	-0.006	-0.4005	No
81	IFNG	5670592	11695	-0.006	-0.4046	No
82	APC	3850484 5860722	11816	-0.006	-0.4110	No
83	ATM	3610110 4050524	11982	-0.007	-0.4198	No
84	JAG1	3440390	12186	-0.008	-0.4306	No
85	NCK1	6200575 6510050	12455	-0.009	-0.4450	No
86	SRC	580132	12478	-0.009	-0.4460	No
87	AKT2	3850541 3870519	12620	-0.010	-0.4534	No
88	NF1	6980433	12719	-0.011	-0.4585	No
89	SYK	6940133	12885	-0.012	-0.4672	No
90	IRS1	1190204	13277	-0.014	-0.4881	No
91	REL	360707	13310	-0.015	-0.4895	No
92	MAP3K5	6020041 6380162	13343	-0.015	-0.4910	No
93	IL15	4560332 5860438	13562	-0.017	-0.5024	No
94	BIRC2	2940435 4730020	13581	-0.017	-0.5031	No
95	PTPRK	1450433 2640142	13831	-0.020	-0.5161	No
96	IFNAR1	4730672	13832	-0.020	-0.5157	No
97	STAT6	1190010 5720019	13858	-0.021	-0.5167	No
98	SHC1	2900731 3170504 6520537	13907	-0.021	-0.5188	No
99	DLG1	2630091 6020286	13917	-0.022	-0.5189	No
100	VIPR1	2480292 5720288 6760537	14482	-0.032	-0.5488	No
101	ARHGAP1	2810010 5270064	14636	-0.036	-0.5563	No
102	ITGB4	1740021 3840482	14703	-0.038	-0.5591	No
103	CXCL12	580546 4150750 4570068	14869	-0.045	-0.5672	No
104	STAT5B	6200026	14943	-0.049	-0.5701	No
105	ITGB7	4670619	14968	-0.050	-0.5704	No
106	ILK	870601 4480180	15077	-0.057	-0.5751	No
107	SFN	6290301 7510608	15114	-0.059	-0.5759	No
108	JAK3	70347 3290008	15166	-0.062	-0.5774	No
109	ITGA5	5550520	15174	-0.063	-0.5765	No
110	ITGB3	5270463	15243	-0.068	-0.5788	No
111	IL18R1	270546	15434	-0.083	-0.5874	No
112	IKBKG	3450092 3840377 6590592	15620	-0.102	-0.5953	No
113	ITGAE	4210632 4670239 5340253 5420746 5690154 5700685 6770154	15630	-0.103	-0.5937	No
114	TIAM1	5420288	15730	-0.113	-0.5968	No
115	FYN	2100468 4760520 4850687	15761	-0.116	-0.5960	No
116	MAP3K8	2940286	15842	-0.125	-0.5978	No
117	JAK1	5910746	15852	-0.127	-0.5957	No
118	ROCK1	130044	16034	-0.147	-0.6025	No
119	ZAP70	1410494 2260504	16061	-0.152	-0.6008	No
120	MAP2K3	5570193	16103	-0.158	-0.5998	No
121	MAP4K4	2360059	16313	-0.188	-0.6073	No
122	SH3BP2	610131	16394	-0.203	-0.6075	Yes
123	CRK	1230162 4780128	16406	-0.206	-0.6039	Yes
124	TYK2	1660465 1740736	16473	-0.219	-0.6030	Yes
125	MAP2K5	2030440	16563	-0.240	-0.6030	Yes
126	TRAF6	4810292 6200132	16620	-0.253	-0.6009	Yes
127	MKNK1	6510161	16654	-0.259	-0.5974	Yes
128	RGS16	780091	16708	-0.272	-0.5947	Yes
129	MYD88	2100717	16819	-0.299	-0.5945	Yes
130	IL2RB	4730072	16889	-0.317	-0.5918	Yes
131	RASA1	1240315	16954	-0.335	-0.5885	Yes
132	PIK3C3	6590717	17008	-0.350	-0.5842	Yes
133	IL6ST	5890047	17016	-0.352	-0.5774	Yes
134	GNB1	2120397	17111	-0.389	-0.5746	Yes
135	PTEN	3390064	17161	-0.403	-0.5691	Yes
136	RELB	1400048	17205	-0.414	-0.5629	Yes
137	AXIN2	3850131	17220	-0.423	-0.5551	Yes
138	TNFRSF4	6840056	17224	-0.423	-0.5466	Yes
139	MAP2K6	1230056 2940204	17261	-0.436	-0.5397	Yes
140	RALBP1	4780632	17268	-0.439	-0.5311	Yes
141	RELA	3830075	17328	-0.467	-0.5247	Yes
142	ITGA6	3830129	17438	-0.512	-0.5202	Yes
143	MAP3K14	5890435	17492	-0.536	-0.5122	Yes
144	STAT2	3780519	17679	-0.645	-0.5091	Yes
145	BCL10	2360397	17788	-0.705	-0.5006	Yes
146	AXIN1	3360358 6940451	17793	-0.709	-0.4864	Yes
147	ITGB2	6380348	17832	-0.734	-0.4735	Yes
148	PIK3CG	5890110	17834	-0.735	-0.4585	Yes
149	VAV1	6020487	17855	-0.751	-0.4443	Yes
150	TNFRSF14	5050438	17871	-0.760	-0.4296	Yes
151	CRKL	4050427	17897	-0.783	-0.4150	Yes
152	DGKQ	2480609	17918	-0.799	-0.3998	Yes
153	ITGAL	1450324	17929	-0.809	-0.3839	Yes
154	STAT3	460040 3710341	18021	-0.893	-0.3706	Yes
155	TRAF1	3440735	18036	-0.911	-0.3528	Yes
156	STAT1	6510204 6590553	18176	-1.089	-0.3382	Yes
157	MAP3K3	610685	18187	-1.104	-0.3162	Yes
158	TRAF3	5690647	18198	-1.124	-0.2938	Yes
159	NOTCH3	3060603	18226	-1.164	-0.2716	Yes
160	IFNGR1	610577	18234	-1.174	-0.2480	Yes
161	PDPK1	6650168	18263	-1.250	-0.2241	Yes
162	IFNAR2	4070687 7100484	18316	-1.364	-0.1991	Yes
163	PTK2B	4730411	18382	-1.574	-0.1705	Yes
164	MAPK9	2060273 3780209 4070397	18430	-1.744	-0.1376	Yes
165	DGKA	5720152 5890328	18492	-2.053	-0.0990	Yes
166	DGKG	1770025	18546	-2.567	-0.0496	Yes
167	TNFRSF1A	1090390 6520735	18550	-2.617	0.0036	Yes