Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_02_ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus.phenotype_ATM_minus_versus_ATM_plus.cls #ATM_minus_versus_ATM_plus_repos |
| Phenotype | phenotype_ATM_minus_versus_ATM_plus.cls#ATM_minus_versus_ATM_plus_repos |
| Upregulated in class | ATM_minus |
| GeneSet | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS |
| Enrichment Score (ES) | 0.7040551 |
| Normalized Enrichment Score (NES) | 1.806401 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.08773495 |
| FWER p-Value | 0.307 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CDK2 | 1416873_a_at 1447617_at | 6 | 5.454 | 0.2967 | Yes | ||
| 2 | MCM6 | 1416251_at 1438852_x_at 1447756_x_at | 291 | 2.041 | 0.3949 | Yes | ||
| 3 | ORC5L | 1415830_at 1441601_at | 478 | 1.634 | 0.4754 | Yes | ||
| 4 | MCM4 | 1416214_at 1436708_x_at | 574 | 1.511 | 0.5534 | Yes | ||
| 5 | CDC25A | 1417131_at 1417132_at 1445995_at | 1166 | 1.019 | 0.5819 | Yes | ||
| 6 | RFC3 | 1423700_at 1432538_a_at | 1310 | 0.938 | 0.6264 | Yes | ||
| 7 | RFC4 | 1424321_at 1438161_s_at | 1513 | 0.845 | 0.6632 | Yes | ||
| 8 | ORC2L | 1418225_at 1418226_at 1418227_at | 1904 | 0.701 | 0.6836 | Yes | ||
| 9 | CDC25C | 1422252_a_at | 2189 | 0.614 | 0.7041 | Yes | ||
| 10 | RPA2 | 1416433_at 1454011_a_at | 3101 | 0.434 | 0.6861 | No | ||
| 11 | CDC45L | 1416575_at 1457838_at | 3499 | 0.388 | 0.6891 | No | ||
| 12 | MCM10 | 1433407_at 1433408_a_at 1454244_at | 4115 | 0.328 | 0.6789 | No | ||
| 13 | MCM7 | 1416030_a_at 1416031_s_at 1438320_s_at | 4253 | 0.317 | 0.6899 | No | ||
| 14 | CHEK1 | 1420031_at 1420032_at 1439208_at 1449708_s_at 1450677_at | 4895 | 0.276 | 0.6757 | No | ||
| 15 | RFC5 | 1452917_at | 5387 | 0.250 | 0.6668 | No | ||
| 16 | MCM3 | 1420029_at 1426653_at | 6514 | 0.200 | 0.6263 | No | ||
| 17 | ORC1L | 1422663_at 1443172_at | 7176 | 0.176 | 0.6057 | No | ||
| 18 | RFC2 | 1417503_at 1457638_x_at 1457669_x_at | 8152 | 0.143 | 0.5690 | No | ||
| 19 | HUS1 | 1418308_at 1425366_a_at | 9250 | 0.110 | 0.5249 | No | ||
| 20 | RPA1 | 1423293_at 1437309_a_at 1441240_at | 9424 | 0.105 | 0.5227 | No | ||
| 21 | MCM5 | 1415945_at 1436808_x_at | 9729 | 0.096 | 0.5141 | No | ||
| 22 | ORC4L | 1423336_at 1423337_at 1431172_at 1453804_a_at | 10101 | 0.085 | 0.5018 | No | ||
| 23 | CDC7 | 1426002_a_at 1426021_a_at | 11602 | 0.042 | 0.4356 | No | ||
| 24 | RAD9B | 1425800_at 1439955_at | 13892 | -0.032 | 0.3329 | No | ||
| 25 | MCM2 | 1434079_s_at 1448777_at | 15390 | -0.096 | 0.2697 | No | ||
| 26 | RAD1 | 1448414_at | 16820 | -0.189 | 0.2148 | No | ||
| 27 | RPA3 | 1448938_at | 18125 | -0.341 | 0.1739 | No |
