Details for gene set PROTEIN_SERINE_THREONINE_KINASE

Table: GSEA Results Summary

Dataset	set03_wtNotch_versus_normalThy
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY
Enrichment Score (ES)	-0.4950432
Normalized Enrichment Score (NES)	-1.8393114
Nominal p-value	0.0011947431
FDR q-value	0.44022653
FWER p-Value	0.896

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	RIPK4	28	7.789	0.0222	No
2	MAPKAPK2	468	3.735	0.0098	No
3	RIPK1	687	3.202	0.0077	No
4	LATS2	698	3.175	0.0169	No
5	NEK4	933	2.820	0.0128	No
6	RPS6KA1	1191	2.561	0.0066	No
7	EIF2AK2	1341	2.409	0.0059	No
8	CDC42BPB	1418	2.342	0.0089	No
9	CHEK2	1465	2.308	0.0135	No
10	RPS6KA3	1667	2.178	0.0092	No
11	STK3	1699	2.159	0.0141	No
12	ROCK2	1708	2.154	0.0202	No
13	PRKAG3	2626	1.683	-0.0244	No
14	CDK9	2630	1.680	-0.0194	No
15	RPS6KA5	3014	1.536	-0.0355	No
16	ERN1	3331	1.420	-0.0483	No
17	TTK	3434	1.386	-0.0496	No
18	RIPK3	3560	1.346	-0.0523	No
19	CSNK1D	3626	1.327	-0.0518	No
20	RPS6KC1	3917	1.236	-0.0637	No
21	PLK4	3925	1.235	-0.0603	No
22	GTF2H1	3951	1.227	-0.0579	No
23	MAP3K6	3960	1.225	-0.0546	No
24	TTN	3978	1.220	-0.0519	No
25	CSNK2B	3994	1.216	-0.0490	No
26	STK19	4099	1.187	-0.0510	No
27	CIT	4246	1.147	-0.0554	No
28	TESK1	4248	1.146	-0.0520	No
29	BCR	4306	1.134	-0.0516	No
30	MARK1	4790	1.017	-0.0747	No
31	RPS6KA2	4865	0.998	-0.0757	No
32	DAPK3	4918	0.988	-0.0755	No
33	MAP3K7	5000	0.970	-0.0769	No
34	STK38	5096	0.947	-0.0792	No
35	MAPK10	5114	0.942	-0.0772	No
36	IRAK3	5241	0.908	-0.0813	No
37	MAPKAPK5	5303	0.891	-0.0819	No
38	TSSK2	5577	0.826	-0.0942	No
39	TESK2	5709	0.797	-0.0988	No
40	HUNK	5726	0.792	-0.0973	No
41	EXOSC10	5824	0.771	-0.1002	No
42	BCKDK	5975	0.738	-0.1061	No
43	PLK1	6008	0.731	-0.1056	No
44	IRAK1	6113	0.708	-0.1091	No
45	MAPK13	6168	0.698	-0.1099	No
46	BRSK2	6299	0.669	-0.1149	No
47	ROCK1	6347	0.656	-0.1154	No
48	PRKAG1	6428	0.642	-0.1178	No
49	CSNK2A2	6537	0.621	-0.1218	No
50	RPS6KB2	6565	0.616	-0.1214	No
51	VRK2	6598	0.609	-0.1212	No
52	AKT1	6886	0.551	-0.1351	No
53	MAP3K9	6919	0.544	-0.1352	No
54	LIMK1	6995	0.530	-0.1377	No
55	PHKG2	7072	0.517	-0.1402	No
56	MAST1	7115	0.508	-0.1409	No
57	NEK2	7349	0.455	-0.1522	No
58	CDK7	7589	0.409	-0.1639	No
59	TSSK6	8108	0.301	-0.1911	No
60	DAPK2	8178	0.287	-0.1939	No
61	ACVR2A	8372	0.250	-0.2036	No
62	ACVR1B	8440	0.237	-0.2065	No
63	PRKCZ	8446	0.236	-0.2061	No
64	ACVR1C	8891	0.147	-0.2297	No
65	TLK1	9043	0.117	-0.2375	No
66	MAP3K10	9073	0.112	-0.2388	No
67	CHUK	9136	0.102	-0.2418	No
68	ACVR1	9653	-0.003	-0.2698	No
69	MAPK4	10018	-0.073	-0.2893	No
70	WNK3	10069	-0.085	-0.2918	No
71	ACVRL1	10103	-0.091	-0.2933	No
72	MAP3K13	10237	-0.118	-0.3001	No
73	TAOK2	10248	-0.120	-0.3003	No
74	ERN2	10560	-0.181	-0.3166	No
75	SGK2	10617	-0.195	-0.3191	No
76	SRPK2	10738	-0.222	-0.3249	No
77	TSSK3	11026	-0.283	-0.3396	No
78	VRK1	11409	-0.363	-0.3592	No
79	MAP3K4	11463	-0.376	-0.3609	No
80	MKNK2	12122	-0.517	-0.3950	No
81	PRKCE	12144	-0.521	-0.3946	No
82	EIF2AK4	12209	-0.535	-0.3964	No
83	PBK	12217	-0.537	-0.3952	No
84	CSNK2A1	12552	-0.617	-0.4114	No
85	MAPK7	12748	-0.663	-0.4199	No
86	STK16	12834	-0.682	-0.4225	No
87	PRKCI	13267	-0.791	-0.4435	No
88	PAK2	13592	-0.871	-0.4584	No
89	NEK11	13594	-0.872	-0.4558	No
90	CDC42BPA	13817	-0.932	-0.4650	No
91	MINK1	13903	-0.959	-0.4667	No
92	EIF2AK1	13989	-0.984	-0.4683	No
93	STK38L	14219	-1.051	-0.4775	No
94	PRKACB	14256	-1.060	-0.4762	No
95	CDKL1	14336	-1.085	-0.4772	No
96	TSSK1A	14358	-1.091	-0.4750	No
97	MAP3K2	14359	-1.091	-0.4717	No
98	MAPK6	14362	-1.092	-0.4685	No
99	TGFBR1	14475	-1.126	-0.4711	No
100	PAK1	14871	-1.265	-0.4887	No
101	ILK	14888	-1.271	-0.4857	No
102	MARK4	15005	-1.319	-0.4879	No
103	MAPK8	15028	-1.330	-0.4851	No
104	WNK4	15213	-1.406	-0.4908	Yes
105	IRAK2	15218	-1.408	-0.4867	Yes
106	HIPK3	15322	-1.453	-0.4878	Yes
107	CDK3	15389	-1.489	-0.4869	Yes
108	MAPK14	15392	-1.490	-0.4825	Yes
109	MAPK12	15410	-1.504	-0.4788	Yes
110	ATM	15455	-1.529	-0.4765	Yes
111	MAP4K1	15494	-1.551	-0.4738	Yes
112	PHKA1	15506	-1.559	-0.4697	Yes
113	CPNE3	15533	-1.574	-0.4663	Yes
114	CDK10	15545	-1.583	-0.4621	Yes
115	CLK1	15599	-1.608	-0.4601	Yes
116	PRKCB1	15618	-1.616	-0.4561	Yes
117	STK17B	15768	-1.700	-0.4590	Yes
118	UHMK1	15785	-1.710	-0.4547	Yes
119	MYLK	15792	-1.714	-0.4498	Yes
120	RIPK2	15887	-1.764	-0.4495	Yes
121	MAP3K5	15909	-1.779	-0.4452	Yes
122	PHKA2	15944	-1.805	-0.4415	Yes
123	MAPK1	15982	-1.834	-0.4380	Yes
124	STK11	16037	-1.869	-0.4352	Yes
125	NLK	16066	-1.886	-0.4310	Yes
126	CSNK1A1	16088	-1.901	-0.4263	Yes
127	NEK6	16221	-1.999	-0.4274	Yes
128	MAP4K5	16226	-2.001	-0.4215	Yes
129	ACVR2B	16359	-2.103	-0.4222	Yes
130	PRKCH	16424	-2.159	-0.4191	Yes
131	PRKD1	16464	-2.190	-0.4146	Yes
132	MKNK1	16480	-2.203	-0.4087	Yes
133	AKT2	16584	-2.289	-0.4073	Yes
134	PLK3	16606	-2.308	-0.4014	Yes
135	LIMK2	16635	-2.331	-0.3958	Yes
136	MAP4K4	16650	-2.348	-0.3894	Yes
137	PINK1	16818	-2.518	-0.3908	Yes
138	LMTK2	16862	-2.568	-0.3853	Yes
139	STK4	16872	-2.580	-0.3779	Yes
140	MAP3K11	16964	-2.684	-0.3747	Yes
141	PRKD3	16992	-2.712	-0.3679	Yes
142	CDK2	17094	-2.849	-0.3647	Yes
143	WNK1	17096	-2.850	-0.3560	Yes
144	PRKX	17128	-2.891	-0.3489	Yes
145	MAPK9	17129	-2.896	-0.3401	Yes
146	GSK3B	17139	-2.906	-0.3317	Yes
147	TLK2	17145	-2.916	-0.3231	Yes
148	STK10	17242	-3.070	-0.3189	Yes
149	CSNK1G2	17295	-3.137	-0.3122	Yes
150	ULK1	17368	-3.262	-0.3062	Yes
151	PIM2	17476	-3.462	-0.3014	Yes
152	MAP4K3	17566	-3.626	-0.2952	Yes
153	EIF2AK3	17575	-3.644	-0.2845	Yes
154	MAP3K8	17644	-3.789	-0.2767	Yes
155	CLK2	17661	-3.812	-0.2659	Yes
156	CDK5	17776	-4.065	-0.2597	Yes
157	MAP3K12	17778	-4.065	-0.2474	Yes
158	SRPK1	17868	-4.293	-0.2391	Yes
159	MAPK11	17912	-4.438	-0.2279	Yes
160	SNF1LK	17954	-4.564	-0.2162	Yes
161	SNF1LK2	18018	-4.752	-0.2052	Yes
162	MAP3K3	18061	-4.882	-0.1926	Yes
163	PIM1	18097	-5.045	-0.1791	Yes
164	BRDT	18136	-5.200	-0.1653	Yes
165	IKBKE	18185	-5.485	-0.1512	Yes
166	BRD2	18187	-5.490	-0.1345	Yes
167	MARK2	18200	-5.546	-0.1183	Yes
168	PDPK1	18265	-5.919	-0.1037	Yes
169	CSNK1E	18290	-6.103	-0.0864	Yes
170	DYRK1A	18303	-6.167	-0.0682	Yes
171	TGFBR2	18307	-6.182	-0.0496	Yes
172	SNRK	18324	-6.276	-0.0313	Yes
173	MAP4K2	18412	-7.157	-0.0142	Yes
174	SGK3	18490	-8.275	0.0068	Yes