Details for gene set PROTEIN_KINASE

Table: GSEA Results Summary

Dataset	set03_wtNotch_versus_normalThy
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	PROTEIN_KINASE_ACTIVITY
Enrichment Score (ES)	-0.4650595
Normalized Enrichment Score (NES)	-1.8155447
Nominal p-value	0.0
FDR q-value	0.29855108
FWER p-Value	0.938

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	RIPK4	28	7.789	0.0147	No
2	MAPKAPK2	468	3.735	-0.0014	No
3	MAP3K7IP1	524	3.584	0.0031	No
4	RIPK1	687	3.202	0.0010	No
5	LATS2	698	3.175	0.0071	No
6	PDGFRB	718	3.142	0.0126	No
7	EPHB2	786	3.039	0.0153	No
8	NEK4	933	2.820	0.0132	No
9	RPS6KA1	1191	2.561	0.0046	No
10	FLT4	1254	2.501	0.0064	No
11	DDR2	1255	2.500	0.0116	No
12	EIF2AK2	1341	2.409	0.0120	No
13	CDC42BPB	1418	2.342	0.0128	No
14	TGFA	1447	2.323	0.0161	No
15	CHEK2	1465	2.308	0.0200	No
16	RPS6KA3	1667	2.178	0.0136	No
17	STK3	1699	2.159	0.0164	No
18	ROCK2	1708	2.154	0.0205	No
19	EPGN	1887	2.045	0.0150	No
20	PDK4	2076	1.949	0.0089	No
21	TYK2	2086	1.942	0.0124	No
22	LYN	2171	1.899	0.0118	No
23	DDR1	2333	1.823	0.0069	No
24	FLT1	2437	1.773	0.0050	No
25	PRKAG3	2626	1.683	-0.0018	No
26	CDK9	2630	1.680	0.0016	No
27	RYK	2944	1.559	-0.0122	No
28	RPS6KA5	3014	1.536	-0.0128	No
29	ROR1	3063	1.518	-0.0122	No
30	PTK7	3303	1.432	-0.0222	No
31	ERN1	3331	1.420	-0.0207	No
32	TYRO3	3347	1.413	-0.0186	No
33	TTK	3434	1.386	-0.0204	No
34	LTK	3507	1.362	-0.0215	No
35	RIPK3	3560	1.346	-0.0215	No
36	CSNK1D	3626	1.327	-0.0223	No
37	MERTK	3667	1.314	-0.0217	No
38	RPS6KC1	3917	1.236	-0.0327	No
39	PLK4	3925	1.235	-0.0305	No
40	GTF2H1	3951	1.227	-0.0293	No
41	FGFR4	3959	1.225	-0.0271	No
42	MAP3K6	3960	1.225	-0.0246	No
43	TTN	3978	1.220	-0.0229	No
44	CSNK2B	3994	1.216	-0.0212	No
45	NRP2	4032	1.205	-0.0207	No
46	STK19	4099	1.187	-0.0218	No
47	CIT	4246	1.147	-0.0274	No
48	TESK1	4248	1.146	-0.0251	No
49	MAP2K7	4298	1.135	-0.0254	No
50	BCR	4306	1.134	-0.0234	No
51	CSF1R	4543	1.075	-0.0340	No
52	EFNA4	4620	1.056	-0.0359	No
53	MARK1	4790	1.017	-0.0430	No
54	RPS6KA2	4865	0.998	-0.0449	No
55	MUSK	4874	0.996	-0.0433	No
56	CCL2	4875	0.996	-0.0412	No
57	DAPK3	4918	0.988	-0.0414	No
58	MAP3K7	5000	0.970	-0.0438	No
59	STK38	5096	0.947	-0.0470	No
60	MAPK10	5114	0.942	-0.0460	No
61	IRAK3	5241	0.908	-0.0509	No
62	MAPKAPK5	5303	0.891	-0.0524	No
63	PDGFRA	5317	0.887	-0.0513	No
64	TSSK2	5577	0.826	-0.0636	No
65	TESK2	5709	0.797	-0.0691	No
66	HUNK	5726	0.792	-0.0683	No
67	TEK	5747	0.785	-0.0678	No
68	EXOSC10	5824	0.771	-0.0703	No
69	PDGFRL	5907	0.754	-0.0732	No
70	BCKDK	5975	0.738	-0.0753	No
71	PLK1	6008	0.731	-0.0755	No
72	IRAK1	6113	0.708	-0.0797	No
73	MAPK13	6168	0.698	-0.0812	No
74	PDK3	6193	0.691	-0.0811	No
75	FGFR1	6252	0.677	-0.0828	No
76	BRSK2	6299	0.669	-0.0839	No
77	PTK6	6329	0.661	-0.0841	No
78	ROCK1	6347	0.656	-0.0837	No
79	PRKAG1	6428	0.642	-0.0867	No
80	TIE1	6522	0.624	-0.0904	No
81	CSNK2A2	6537	0.621	-0.0899	No
82	RPS6KB2	6565	0.616	-0.0901	No
83	VRK2	6598	0.609	-0.0906	No
84	TWF1	6845	0.558	-0.1028	No
85	AKT1	6886	0.551	-0.1038	No
86	MAP3K9	6919	0.544	-0.1044	No
87	LIMK1	6995	0.530	-0.1074	No
88	PHKG2	7072	0.517	-0.1105	No
89	MAST1	7115	0.508	-0.1117	No
90	EPHA5	7146	0.502	-0.1123	No
91	ROR2	7248	0.476	-0.1168	No
92	NEK2	7349	0.455	-0.1213	No
93	EFNA3	7488	0.427	-0.1279	No
94	CDK7	7589	0.409	-0.1325	No
95	EFNB3	7863	0.352	-0.1466	No
96	TSSK6	8108	0.301	-0.1593	No
97	DAPK2	8178	0.287	-0.1624	No
98	MAPKAPK3	8256	0.270	-0.1661	No
99	ACVR2A	8372	0.250	-0.1718	No
100	ACVR1B	8440	0.237	-0.1750	No
101	PRKCZ	8446	0.236	-0.1747	No
102	TXK	8749	0.174	-0.1908	No
103	ACVR1C	8891	0.147	-0.1982	No
104	TLK1	9043	0.117	-0.2062	No
105	MAP3K10	9073	0.112	-0.2075	No
106	CHUK	9136	0.102	-0.2107	No
107	MAP2K1	9431	0.042	-0.2266	No
108	FRK	9494	0.028	-0.2299	No
109	ACVR1	9653	-0.003	-0.2385	No
110	NTRK1	9683	-0.009	-0.2401	No
111	MAPK4	10018	-0.073	-0.2581	No
112	WNK3	10069	-0.085	-0.2606	No
113	ACVRL1	10103	-0.091	-0.2622	No
114	MAP3K13	10237	-0.118	-0.2692	No
115	KDR	10240	-0.118	-0.2691	No
116	TAOK2	10248	-0.120	-0.2692	No
117	MAP2K3	10511	-0.169	-0.2831	No
118	ERN2	10560	-0.181	-0.2854	No
119	SGK2	10617	-0.195	-0.2880	No
120	SRPK2	10738	-0.222	-0.2941	No
121	TSSK3	11026	-0.283	-0.3091	No
122	VRK1	11409	-0.363	-0.3292	No
123	MAP3K4	11463	-0.376	-0.3313	No
124	MKNK2	12122	-0.517	-0.3660	No
125	PRKCE	12144	-0.521	-0.3661	No
126	ERBB4	12162	-0.525	-0.3659	No
127	ERBB2	12170	-0.526	-0.3652	No
128	MST1R	12208	-0.535	-0.3661	No
129	EIF2AK4	12209	-0.535	-0.3650	No
130	PBK	12217	-0.537	-0.3642	No
131	CSNK2A1	12552	-0.617	-0.3811	No
132	MAPK7	12748	-0.663	-0.3904	No
133	STK16	12834	-0.682	-0.3936	No
134	FLT3	12882	-0.693	-0.3947	No
135	TRIB1	12966	-0.713	-0.3977	No
136	KIT	13043	-0.731	-0.4003	No
137	EGFR	13064	-0.736	-0.3999	No
138	PRKCI	13267	-0.791	-0.4092	No
139	CCL4	13467	-0.840	-0.4183	No
140	PAK2	13592	-0.871	-0.4232	No
141	NEK11	13594	-0.872	-0.4215	No
142	CDC42BPA	13817	-0.932	-0.4316	No
143	TRIM27	13862	-0.945	-0.4320	No
144	MINK1	13903	-0.959	-0.4322	No
145	MET	13922	-0.967	-0.4312	No
146	EIF2AK1	13989	-0.984	-0.4327	No
147	STK38L	14219	-1.051	-0.4430	No
148	PRKACB	14256	-1.060	-0.4427	No
149	ALK	14320	-1.081	-0.4439	No
150	CDKL1	14336	-1.085	-0.4425	No
151	TSSK1A	14358	-1.091	-0.4413	No
152	MAP3K2	14359	-1.091	-0.4390	No
153	MAPK6	14362	-1.092	-0.4369	No
154	TGFBR1	14475	-1.126	-0.4406	No
155	ERBB3	14614	-1.169	-0.4457	No
156	AXL	14846	-1.255	-0.4557	No
157	PAK1	14871	-1.265	-0.4543	No
158	ILK	14888	-1.271	-0.4525	No
159	MARK4	15005	-1.319	-0.4561	No
160	MAPK8	15028	-1.330	-0.4545	No
161	WNK4	15213	-1.406	-0.4616	No
162	IRAK2	15218	-1.408	-0.4589	No
163	HIPK3	15322	-1.453	-0.4615	No
164	CDK3	15389	-1.489	-0.4620	Yes
165	MAPK14	15392	-1.490	-0.4590	Yes
166	MAPK12	15410	-1.504	-0.4567	Yes
167	ATM	15455	-1.529	-0.4559	Yes
168	MAP4K1	15494	-1.551	-0.4548	Yes
169	PHKA1	15506	-1.559	-0.4521	Yes
170	CPNE3	15533	-1.574	-0.4503	Yes
171	CDK10	15545	-1.583	-0.4475	Yes
172	CLK1	15599	-1.608	-0.4471	Yes
173	PRKCB1	15618	-1.616	-0.4447	Yes
174	STK17B	15768	-1.700	-0.4492	Yes
175	UHMK1	15785	-1.710	-0.4466	Yes
176	MYLK	15792	-1.714	-0.4433	Yes
177	PDK1	15809	-1.722	-0.4406	Yes
178	RIPK2	15887	-1.764	-0.4411	Yes
179	MAP3K5	15909	-1.779	-0.4385	Yes
180	PHKA2	15944	-1.805	-0.4366	Yes
181	MAPK1	15982	-1.834	-0.4348	Yes
182	STK11	16037	-1.869	-0.4338	Yes
183	NLK	16066	-1.886	-0.4314	Yes
184	CSNK1A1	16088	-1.901	-0.4286	Yes
185	NEK6	16221	-1.999	-0.4316	Yes
186	MAP4K5	16226	-2.001	-0.4277	Yes
187	INSR	16269	-2.034	-0.4257	Yes
188	CAMKK2	16332	-2.086	-0.4247	Yes
189	ACVR2B	16359	-2.103	-0.4217	Yes
190	PRKCH	16424	-2.159	-0.4207	Yes
191	PRKD1	16464	-2.190	-0.4183	Yes
192	MKNK1	16480	-2.203	-0.4145	Yes
193	CRIM1	16549	-2.253	-0.4135	Yes
194	PXK	16553	-2.258	-0.4090	Yes
195	AKT2	16584	-2.289	-0.4058	Yes
196	PLK3	16606	-2.308	-0.4021	Yes
197	LIMK2	16635	-2.331	-0.3988	Yes
198	MAP4K4	16650	-2.348	-0.3947	Yes
199	EPHB6	16688	-2.383	-0.3917	Yes
200	TRIB2	16696	-2.391	-0.3871	Yes
201	PINK1	16818	-2.518	-0.3884	Yes
202	LMTK2	16862	-2.568	-0.3854	Yes
203	STK4	16872	-2.580	-0.3805	Yes
204	MAP3K11	16964	-2.684	-0.3799	Yes
205	PRKD3	16992	-2.712	-0.3757	Yes
206	COL4A3BP	17051	-2.787	-0.3730	Yes
207	CDK2	17094	-2.849	-0.3694	Yes
208	WNK1	17096	-2.850	-0.3635	Yes
209	PRKX	17128	-2.891	-0.3591	Yes
210	MAPK9	17129	-2.896	-0.3531	Yes
211	GSK3B	17139	-2.906	-0.3475	Yes
212	TLK2	17145	-2.916	-0.3417	Yes
213	STK10	17242	-3.070	-0.3405	Yes
214	CSNK1G2	17295	-3.137	-0.3368	Yes
215	ULK1	17368	-3.262	-0.3339	Yes
216	TNK2	17436	-3.383	-0.3305	Yes
217	PIM2	17476	-3.462	-0.3254	Yes
218	IGF1R	17477	-3.463	-0.3182	Yes
219	IGF2R	17484	-3.475	-0.3112	Yes
220	MAP4K3	17566	-3.626	-0.3081	Yes
221	EIF2AK3	17575	-3.644	-0.3009	Yes
222	MAP3K8	17644	-3.789	-0.2967	Yes
223	CLK2	17661	-3.812	-0.2896	Yes
224	ALS2CR2	17662	-3.813	-0.2817	Yes
225	CDK5	17776	-4.065	-0.2793	Yes
226	MAP3K12	17778	-4.065	-0.2709	Yes
227	SRPK1	17868	-4.293	-0.2668	Yes
228	MAPK11	17912	-4.438	-0.2599	Yes
229	MAP2K6	17919	-4.460	-0.2509	Yes
230	SNF1LK	17954	-4.564	-0.2432	Yes
231	CRKL	17994	-4.686	-0.2356	Yes
232	SNF1LK2	18018	-4.752	-0.2269	Yes
233	MAP3K3	18061	-4.882	-0.2190	Yes
234	PDK2	18065	-4.903	-0.2089	Yes
235	PIM1	18097	-5.045	-0.2001	Yes
236	BRDT	18136	-5.200	-0.1913	Yes
237	IKBKE	18185	-5.485	-0.1825	Yes
238	BRD2	18187	-5.490	-0.1711	Yes
239	MARK2	18200	-5.546	-0.1602	Yes
240	PDPK1	18265	-5.919	-0.1513	Yes
241	CSNK1E	18290	-6.103	-0.1399	Yes
242	DYRK1A	18303	-6.167	-0.1276	Yes
243	TGFBR2	18307	-6.182	-0.1149	Yes
244	SNRK	18324	-6.276	-0.1027	Yes
245	MAP4K2	18412	-7.157	-0.0925	Yes
246	ITK	18446	-7.525	-0.0786	Yes
247	CDK5R1	18479	-8.062	-0.0635	Yes
248	SGK3	18490	-8.275	-0.0468	Yes
249	PTK2B	18539	-9.957	-0.0286	Yes
250	TEC	18587	-15.689	0.0016	Yes