Dataset | set03_wtNotch_versus_normalThy |
Phenotype | NoPhenotypeAvailable |
Upregulated in class | na_pos |
GeneSet | MITOCHONDRION |
Enrichment Score (ES) | 0.44544226 |
Normalized Enrichment Score (NES) | 2.126301 |
Nominal p-value | 0.0 |
FDR q-value | 0.002076345 |
FWER p-Value | 0.013 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | PHB2 | 29 | 7.701 | 0.0124 | Yes | ||
2 | TIMM50 | 30 | 7.513 | 0.0260 | Yes | ||
3 | SHMT2 | 32 | 7.432 | 0.0394 | Yes | ||
4 | ABCB6 | 35 | 7.229 | 0.0524 | Yes | ||
5 | BAX | 38 | 6.993 | 0.0650 | Yes | ||
6 | TIMM10 | 44 | 6.849 | 0.0772 | Yes | ||
7 | MRPS10 | 59 | 6.411 | 0.0880 | Yes | ||
8 | GOT2 | 92 | 5.775 | 0.0968 | Yes | ||
9 | SOD2 | 112 | 5.520 | 0.1057 | Yes | ||
10 | TIMM13 | 118 | 5.483 | 0.1154 | Yes | ||
11 | MECR | 142 | 5.186 | 0.1236 | Yes | ||
12 | TXNRD2 | 162 | 5.034 | 0.1316 | Yes | ||
13 | CYC1 | 173 | 4.902 | 0.1400 | Yes | ||
14 | IMMT | 182 | 4.852 | 0.1484 | Yes | ||
15 | ATP5G1 | 202 | 4.726 | 0.1559 | Yes | ||
16 | SLC25A3 | 234 | 4.571 | 0.1625 | Yes | ||
17 | NDUFV1 | 241 | 4.535 | 0.1704 | Yes | ||
18 | MRPS15 | 259 | 4.452 | 0.1775 | Yes | ||
19 | TBRG4 | 268 | 4.431 | 0.1851 | Yes | ||
20 | SOD1 | 275 | 4.404 | 0.1928 | Yes | ||
21 | ETFB | 281 | 4.358 | 0.2004 | Yes | ||
22 | MRPS28 | 288 | 4.334 | 0.2080 | Yes | ||
23 | MRPL55 | 322 | 4.235 | 0.2138 | Yes | ||
24 | HSPD1 | 415 | 3.873 | 0.2159 | Yes | ||
25 | MRPL12 | 419 | 3.849 | 0.2227 | Yes | ||
26 | FPGS | 451 | 3.774 | 0.2278 | Yes | ||
27 | DLD | 461 | 3.746 | 0.2341 | Yes | ||
28 | ATP5G2 | 485 | 3.705 | 0.2396 | Yes | ||
29 | PTGES2 | 504 | 3.635 | 0.2452 | Yes | ||
30 | ETFA | 540 | 3.558 | 0.2497 | Yes | ||
31 | SUPV3L1 | 547 | 3.543 | 0.2558 | Yes | ||
32 | BCS1L | 563 | 3.501 | 0.2614 | Yes | ||
33 | UQCRC1 | 568 | 3.493 | 0.2675 | Yes | ||
34 | ACADS | 593 | 3.424 | 0.2724 | Yes | ||
35 | SDHB | 594 | 3.417 | 0.2786 | Yes | ||
36 | ABCF2 | 615 | 3.369 | 0.2836 | Yes | ||
37 | LONP1 | 638 | 3.306 | 0.2884 | Yes | ||
38 | MRPS18A | 668 | 3.244 | 0.2927 | Yes | ||
39 | GHITM | 677 | 3.226 | 0.2981 | Yes | ||
40 | AIFM2 | 683 | 3.215 | 0.3037 | Yes | ||
41 | MRPS11 | 695 | 3.185 | 0.3089 | Yes | ||
42 | ACAT1 | 696 | 3.182 | 0.3146 | Yes | ||
43 | COQ7 | 721 | 3.136 | 0.3190 | Yes | ||
44 | BID | 751 | 3.087 | 0.3230 | Yes | ||
45 | FDXR | 766 | 3.067 | 0.3278 | Yes | ||
46 | TOMM22 | 836 | 2.951 | 0.3294 | Yes | ||
47 | GSTZ1 | 860 | 2.914 | 0.3334 | Yes | ||
48 | TRNT1 | 869 | 2.895 | 0.3383 | Yes | ||
49 | ECSIT | 929 | 2.822 | 0.3402 | Yes | ||
50 | COX15 | 949 | 2.798 | 0.3442 | Yes | ||
51 | KARS | 958 | 2.790 | 0.3488 | Yes | ||
52 | MRPS35 | 964 | 2.787 | 0.3536 | Yes | ||
53 | MTCH1 | 972 | 2.775 | 0.3583 | Yes | ||
54 | NT5M | 1030 | 2.722 | 0.3601 | Yes | ||
55 | DBT | 1063 | 2.689 | 0.3632 | Yes | ||
56 | NDUFA8 | 1066 | 2.688 | 0.3680 | Yes | ||
57 | ATP5E | 1097 | 2.652 | 0.3712 | Yes | ||
58 | PCCB | 1121 | 2.623 | 0.3747 | Yes | ||
59 | HADH | 1135 | 2.608 | 0.3787 | Yes | ||
60 | ABCB7 | 1335 | 2.414 | 0.3722 | Yes | ||
61 | SLC25A1 | 1379 | 2.378 | 0.3742 | Yes | ||
62 | CYCS | 1401 | 2.360 | 0.3773 | Yes | ||
63 | MRPS18C | 1428 | 2.337 | 0.3801 | Yes | ||
64 | FIBP | 1471 | 2.304 | 0.3820 | Yes | ||
65 | OPA1 | 1488 | 2.293 | 0.3853 | Yes | ||
66 | ATP5G3 | 1512 | 2.282 | 0.3882 | Yes | ||
67 | SURF1 | 1521 | 2.278 | 0.3919 | Yes | ||
68 | SLC25A13 | 1606 | 2.217 | 0.3913 | Yes | ||
69 | VDAC2 | 1627 | 2.208 | 0.3942 | Yes | ||
70 | NDUFS7 | 1656 | 2.186 | 0.3967 | Yes | ||
71 | TIMM17A | 1661 | 2.183 | 0.4004 | Yes | ||
72 | GLUD1 | 1676 | 2.172 | 0.4036 | Yes | ||
73 | MTRF1 | 1685 | 2.167 | 0.4071 | Yes | ||
74 | PMPCA | 1693 | 2.163 | 0.4106 | Yes | ||
75 | TP53 | 1792 | 2.107 | 0.4091 | Yes | ||
76 | VDAC3 | 1826 | 2.080 | 0.4111 | Yes | ||
77 | MRPS24 | 1892 | 2.043 | 0.4112 | Yes | ||
78 | VDAC1 | 1902 | 2.039 | 0.4145 | Yes | ||
79 | HINT2 | 2056 | 1.958 | 0.4097 | Yes | ||
80 | PDK4 | 2076 | 1.949 | 0.4122 | Yes | ||
81 | ECHS1 | 2314 | 1.832 | 0.4026 | Yes | ||
82 | HSD17B10 | 2356 | 1.812 | 0.4036 | Yes | ||
83 | ACADVL | 2382 | 1.802 | 0.4055 | Yes | ||
84 | PECI | 2416 | 1.785 | 0.4070 | Yes | ||
85 | MRPS12 | 2483 | 1.749 | 0.4065 | Yes | ||
86 | ACP6 | 2490 | 1.745 | 0.4094 | Yes | ||
87 | TFB2M | 2506 | 1.737 | 0.4117 | Yes | ||
88 | ATP5D | 2522 | 1.729 | 0.4140 | Yes | ||
89 | ACO2 | 2536 | 1.725 | 0.4164 | Yes | ||
90 | TIMM23 | 2566 | 1.710 | 0.4180 | Yes | ||
91 | COX6B2 | 2679 | 1.655 | 0.4149 | Yes | ||
92 | SLC25A4 | 2741 | 1.631 | 0.4145 | Yes | ||
93 | ACN9 | 2756 | 1.628 | 0.4167 | Yes | ||
94 | ATP5F1 | 2805 | 1.609 | 0.4170 | Yes | ||
95 | GPX4 | 2822 | 1.603 | 0.4190 | Yes | ||
96 | COQ6 | 2835 | 1.599 | 0.4213 | Yes | ||
97 | TUFM | 2864 | 1.589 | 0.4226 | Yes | ||
98 | NDUFAB1 | 2929 | 1.565 | 0.4220 | Yes | ||
99 | MTHFD1 | 2967 | 1.551 | 0.4228 | Yes | ||
100 | ATP5C1 | 2990 | 1.541 | 0.4244 | Yes | ||
101 | NME4 | 3033 | 1.530 | 0.4248 | Yes | ||
102 | OAT | 3053 | 1.521 | 0.4266 | Yes | ||
103 | UQCRB | 3055 | 1.521 | 0.4293 | Yes | ||
104 | AIFM1 | 3067 | 1.516 | 0.4314 | Yes | ||
105 | PSEN1 | 3087 | 1.509 | 0.4331 | Yes | ||
106 | IDH3B | 3152 | 1.484 | 0.4323 | Yes | ||
107 | COX4NB | 3156 | 1.483 | 0.4349 | Yes | ||
108 | GATM | 3191 | 1.470 | 0.4357 | Yes | ||
109 | SUCLA2 | 3217 | 1.464 | 0.4370 | Yes | ||
110 | NR3C1 | 3247 | 1.453 | 0.4380 | Yes | ||
111 | HSD3B2 | 3258 | 1.449 | 0.4401 | Yes | ||
112 | SDHD | 3348 | 1.413 | 0.4378 | Yes | ||
113 | CLN3 | 3362 | 1.408 | 0.4397 | Yes | ||
114 | ALDH5A1 | 3470 | 1.373 | 0.4363 | Yes | ||
115 | MRPL10 | 3481 | 1.370 | 0.4382 | Yes | ||
116 | MRPL51 | 3496 | 1.366 | 0.4400 | Yes | ||
117 | SUCLG1 | 3530 | 1.354 | 0.4406 | Yes | ||
118 | HSPE1 | 3571 | 1.343 | 0.4409 | Yes | ||
119 | AMT | 3609 | 1.332 | 0.4413 | Yes | ||
120 | NDUFA6 | 3615 | 1.331 | 0.4434 | Yes | ||
121 | LDHD | 3623 | 1.329 | 0.4454 | Yes | ||
122 | MRPS31 | 3683 | 1.309 | 0.4446 | No | ||
123 | NFS1 | 3789 | 1.281 | 0.4412 | No | ||
124 | NDUFS2 | 3794 | 1.278 | 0.4433 | No | ||
125 | RAB11FIP5 | 3868 | 1.252 | 0.4416 | No | ||
126 | SDHC | 3909 | 1.238 | 0.4417 | No | ||
127 | UCP3 | 3995 | 1.216 | 0.4392 | No | ||
128 | PDHA1 | 4004 | 1.213 | 0.4410 | No | ||
129 | ATP5O | 4080 | 1.191 | 0.4391 | No | ||
130 | BAK1 | 4139 | 1.175 | 0.4380 | No | ||
131 | NDUFS8 | 4177 | 1.165 | 0.4381 | No | ||
132 | LRPPRC | 4294 | 1.136 | 0.4339 | No | ||
133 | ATP5J | 4340 | 1.126 | 0.4334 | No | ||
134 | MTERF | 4363 | 1.122 | 0.4343 | No | ||
135 | PIN4 | 4539 | 1.076 | 0.4267 | No | ||
136 | CHCHD3 | 4628 | 1.054 | 0.4238 | No | ||
137 | HAX1 | 4723 | 1.032 | 0.4206 | No | ||
138 | ACOT2 | 4819 | 1.010 | 0.4172 | No | ||
139 | MFN2 | 4917 | 0.988 | 0.4137 | No | ||
140 | NDUFA1 | 5129 | 0.937 | 0.4039 | No | ||
141 | NLRP5 | 5160 | 0.928 | 0.4040 | No | ||
142 | HADHB | 5176 | 0.925 | 0.4048 | No | ||
143 | GRPEL1 | 5304 | 0.891 | 0.3995 | No | ||
144 | POLG2 | 5412 | 0.862 | 0.3952 | No | ||
145 | MAOB | 5417 | 0.860 | 0.3966 | No | ||
146 | CLPX | 5479 | 0.848 | 0.3948 | No | ||
147 | CS | 5656 | 0.810 | 0.3867 | No | ||
148 | PET112L | 5760 | 0.782 | 0.3825 | No | ||
149 | DECR1 | 5806 | 0.774 | 0.3814 | No | ||
150 | ATP5A1 | 5869 | 0.760 | 0.3794 | No | ||
151 | BCKDK | 5975 | 0.738 | 0.3750 | No | ||
152 | CPT1B | 5986 | 0.735 | 0.3758 | No | ||
153 | TIMM9 | 6130 | 0.705 | 0.3693 | No | ||
154 | PDK3 | 6193 | 0.691 | 0.3672 | No | ||
155 | SARS2 | 6257 | 0.676 | 0.3650 | No | ||
156 | NIPSNAP1 | 6644 | 0.599 | 0.3450 | No | ||
157 | MTX2 | 6719 | 0.587 | 0.3420 | No | ||
158 | CENTA2 | 6808 | 0.568 | 0.3383 | No | ||
159 | MTIF2 | 6935 | 0.543 | 0.3324 | No | ||
160 | HTRA2 | 6949 | 0.541 | 0.3326 | No | ||
161 | CRY1 | 6997 | 0.530 | 0.3310 | No | ||
162 | BNIP3L | 7206 | 0.487 | 0.3206 | No | ||
163 | MRPS16 | 7217 | 0.483 | 0.3209 | No | ||
164 | ISCU | 7258 | 0.474 | 0.3196 | No | ||
165 | NDUFA9 | 7272 | 0.470 | 0.3197 | No | ||
166 | CKMT2 | 7331 | 0.458 | 0.3174 | No | ||
167 | SARDH | 7367 | 0.451 | 0.3163 | No | ||
168 | BPHL | 7373 | 0.449 | 0.3169 | No | ||
169 | MRPS22 | 7418 | 0.441 | 0.3153 | No | ||
170 | MTHFD2 | 7423 | 0.440 | 0.3158 | No | ||
171 | NDUFA11 | 7499 | 0.425 | 0.3125 | No | ||
172 | SLC25A27 | 7780 | 0.372 | 0.2979 | No | ||
173 | COX8C | 7910 | 0.342 | 0.2915 | No | ||
174 | MRPL52 | 8032 | 0.319 | 0.2855 | No | ||
175 | BDH2 | 8067 | 0.311 | 0.2842 | No | ||
176 | ESR2 | 8102 | 0.303 | 0.2829 | No | ||
177 | HCCS | 8128 | 0.297 | 0.2821 | No | ||
178 | PTRF | 8520 | 0.221 | 0.2612 | No | ||
179 | SLC25A15 | 8638 | 0.197 | 0.2552 | No | ||
180 | GCDH | 8652 | 0.194 | 0.2548 | No | ||
181 | DMGDH | 9084 | 0.111 | 0.2315 | No | ||
182 | NDUFS5 | 9118 | 0.105 | 0.2299 | No | ||
183 | CASP8 | 9176 | 0.093 | 0.2269 | No | ||
184 | HSD3B1 | 9529 | 0.020 | 0.2078 | No | ||
185 | IDH2 | 9687 | -0.009 | 0.1993 | No | ||
186 | BCL2L10 | 10091 | -0.090 | 0.1774 | No | ||
187 | GLYAT | 10302 | -0.130 | 0.1662 | No | ||
188 | PITRM1 | 10303 | -0.130 | 0.1665 | No | ||
189 | GLRX2 | 10341 | -0.136 | 0.1647 | No | ||
190 | SDHA | 10362 | -0.140 | 0.1639 | No | ||
191 | HMGCS2 | 10557 | -0.180 | 0.1536 | No | ||
192 | AFG3L2 | 10623 | -0.198 | 0.1504 | No | ||
193 | BCKDHB | 10656 | -0.205 | 0.1490 | No | ||
194 | ATPIF1 | 11000 | -0.279 | 0.1309 | No | ||
195 | BCKDHA | 11247 | -0.328 | 0.1180 | No | ||
196 | RHOT1 | 11518 | -0.388 | 0.1040 | No | ||
197 | COQ4 | 11682 | -0.423 | 0.0959 | No | ||
198 | CPT1A | 11693 | -0.425 | 0.0961 | No | ||
199 | MRPL40 | 11741 | -0.439 | 0.0944 | No | ||
200 | CASQ1 | 11793 | -0.450 | 0.0924 | No | ||
201 | MUT | 11987 | -0.484 | 0.0828 | No | ||
202 | COX11 | 12078 | -0.507 | 0.0788 | No | ||
203 | PPOX | 12093 | -0.511 | 0.0789 | No | ||
204 | MIPEP | 12117 | -0.516 | 0.0786 | No | ||
205 | PHB | 12202 | -0.533 | 0.0750 | No | ||
206 | ABAT | 12204 | -0.533 | 0.0759 | No | ||
207 | ALDH4A1 | 12570 | -0.621 | 0.0571 | No | ||
208 | POLRMT | 12593 | -0.628 | 0.0571 | No | ||
209 | MRPL23 | 12605 | -0.630 | 0.0576 | No | ||
210 | MRPS36 | 12613 | -0.631 | 0.0584 | No | ||
211 | SLC25A22 | 12726 | -0.658 | 0.0535 | No | ||
212 | GBAS | 12928 | -0.704 | 0.0438 | No | ||
213 | DHRS4 | 12988 | -0.716 | 0.0419 | No | ||
214 | BNIP3 | 12999 | -0.719 | 0.0426 | No | ||
215 | FXN | 13105 | -0.747 | 0.0383 | No | ||
216 | ABCE1 | 13383 | -0.819 | 0.0246 | No | ||
217 | FDX1 | 13414 | -0.827 | 0.0245 | No | ||
218 | SLC22A4 | 13418 | -0.828 | 0.0258 | No | ||
219 | COX7A1 | 13427 | -0.829 | 0.0269 | No | ||
220 | SLC9A6 | 13447 | -0.835 | 0.0274 | No | ||
221 | TIMM17B | 13468 | -0.840 | 0.0278 | No | ||
222 | NDUFA4 | 13684 | -0.895 | 0.0177 | No | ||
223 | ACOT9 | 13789 | -0.924 | 0.0137 | No | ||
224 | OXCT1 | 13887 | -0.955 | 0.0102 | No | ||
225 | TIMM44 | 13979 | -0.982 | 0.0070 | No | ||
226 | CPOX | 14049 | -0.998 | 0.0050 | No | ||
227 | TIMM8B | 14121 | -1.019 | 0.0030 | No | ||
228 | SLC25A12 | 14299 | -1.075 | -0.0047 | No | ||
229 | ATP5B | 14686 | -1.194 | -0.0236 | No | ||
230 | DNAJA3 | 14760 | -1.218 | -0.0253 | No | ||
231 | AMACR | 14906 | -1.277 | -0.0309 | No | ||
232 | BBC3 | 14955 | -1.297 | -0.0312 | No | ||
233 | BZRAP1 | 14965 | -1.300 | -0.0293 | No | ||
234 | NDUFS3 | 15097 | -1.356 | -0.0340 | No | ||
235 | SPG7 | 15204 | -1.403 | -0.0372 | No | ||
236 | MPV17 | 15342 | -1.466 | -0.0420 | No | ||
237 | NDUFA2 | 15344 | -1.467 | -0.0394 | No | ||
238 | OGDH | 15383 | -1.486 | -0.0388 | No | ||
239 | AASS | 15396 | -1.494 | -0.0368 | No | ||
240 | UQCRH | 15411 | -1.506 | -0.0348 | No | ||
241 | TOMM34 | 15458 | -1.530 | -0.0345 | No | ||
242 | ACADSB | 15609 | -1.613 | -0.0398 | No | ||
243 | ARG2 | 15612 | -1.614 | -0.0370 | No | ||
244 | NNT | 15616 | -1.616 | -0.0342 | No | ||
245 | PDK1 | 15809 | -1.722 | -0.0415 | No | ||
246 | FIS1 | 15831 | -1.735 | -0.0395 | No | ||
247 | LETM1 | 15906 | -1.775 | -0.0403 | No | ||
248 | RAF1 | 15947 | -1.805 | -0.0393 | No | ||
249 | NDUFS1 | 16100 | -1.909 | -0.0441 | No | ||
250 | PMAIP1 | 16231 | -2.004 | -0.0475 | No | ||
251 | MSRB2 | 16322 | -2.081 | -0.0487 | No | ||
252 | DGUOK | 16481 | -2.203 | -0.0533 | No | ||
253 | BCAT2 | 16540 | -2.245 | -0.0524 | No | ||
254 | MRPL32 | 16578 | -2.283 | -0.0502 | No | ||
255 | PRDX5 | 16599 | -2.300 | -0.0472 | No | ||
256 | SLC25A14 | 16641 | -2.336 | -0.0452 | No | ||
257 | TFAM | 16658 | -2.353 | -0.0418 | No | ||
258 | CKMT1A | 16712 | -2.406 | -0.0403 | No | ||
259 | PINK1 | 16818 | -2.518 | -0.0415 | No | ||
260 | NDUFA13 | 16881 | -2.593 | -0.0401 | No | ||
261 | NDUFS4 | 16892 | -2.602 | -0.0360 | No | ||
262 | ACADM | 16942 | -2.663 | -0.0338 | No | ||
263 | MRPS21 | 17055 | -2.793 | -0.0348 | No | ||
264 | POLG | 17186 | -2.973 | -0.0365 | No | ||
265 | ASAH2 | 17243 | -3.070 | -0.0340 | No | ||
266 | BCL2L1 | 17522 | -3.558 | -0.0427 | No | ||
267 | DIABLO | 17625 | -3.729 | -0.0415 | No | ||
268 | PTS | 17823 | -4.167 | -0.0447 | No | ||
269 | RHOT2 | 18183 | -5.480 | -0.0543 | No | ||
270 | MCL1 | 18226 | -5.653 | -0.0464 | No | ||
271 | ALAS2 | 18249 | -5.792 | -0.0371 | No | ||
272 | SLC25A11 | 18345 | -6.504 | -0.0305 | No | ||
273 | MYLC2PL | 18439 | -7.465 | -0.0220 | No | ||
274 | CASP7 | 18463 | -7.844 | -0.0090 | No | ||
275 | BCL2 | 18530 | -9.542 | 0.0047 | No |