Dataset | set03_wtNotch_versus_normalThy |
Phenotype | NoPhenotypeAvailable |
Upregulated in class | na_neg |
GeneSet | AGCACTT,MIR-93,MIR-302A,MIR-302B,MIR-302C,MIR-302D,MIR-372,MIR-373,MIR-520E,MIR-520A,MIR-526B,MIR-520B,MIR-520C,MIR-520D |
Enrichment Score (ES) | -0.48172426 |
Normalized Enrichment Score (NES) | -1.8490916 |
Nominal p-value | 0.0 |
FDR q-value | 0.09144622 |
FWER p-Value | 0.416 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | PCDHA7 | 265 | 4.437 | -0.0050 | No | ||
2 | OSBPL5 | 328 | 4.215 | 0.0007 | No | ||
3 | RBBP7 | 416 | 3.867 | 0.0042 | No | ||
4 | CCND1 | 475 | 3.721 | 0.0089 | No | ||
5 | SLC6A9 | 484 | 3.705 | 0.0164 | No | ||
6 | DNAJA2 | 534 | 3.562 | 0.0213 | No | ||
7 | LATS2 | 698 | 3.175 | 0.0192 | No | ||
8 | TRIM36 | 702 | 3.171 | 0.0258 | No | ||
9 | PBX3 | 833 | 2.954 | 0.0250 | No | ||
10 | OXR1 | 886 | 2.877 | 0.0283 | No | ||
11 | RALGDS | 921 | 2.832 | 0.0325 | No | ||
12 | TNFAIP1 | 927 | 2.827 | 0.0383 | No | ||
13 | DDHD1 | 1189 | 2.562 | 0.0295 | No | ||
14 | RPS6KA1 | 1191 | 2.561 | 0.0349 | No | ||
15 | ADAM9 | 1259 | 2.494 | 0.0366 | No | ||
16 | RGMA | 1364 | 2.390 | 0.0360 | No | ||
17 | ATAD2 | 1479 | 2.298 | 0.0347 | No | ||
18 | SYNC1 | 1509 | 2.283 | 0.0380 | No | ||
19 | MUTED | 1514 | 2.281 | 0.0427 | No | ||
20 | SDC1 | 1559 | 2.248 | 0.0451 | No | ||
21 | DCUN1D1 | 1598 | 2.222 | 0.0477 | No | ||
22 | CRK | 1653 | 2.190 | 0.0495 | No | ||
23 | RPS6KA3 | 1667 | 2.178 | 0.0534 | No | ||
24 | DMTF1 | 1743 | 2.133 | 0.0539 | No | ||
25 | AK2 | 1819 | 2.089 | 0.0542 | No | ||
26 | LUC7L2 | 2108 | 1.932 | 0.0427 | No | ||
27 | FNDC3A | 2115 | 1.929 | 0.0465 | No | ||
28 | ASF1A | 2417 | 1.784 | 0.0339 | No | ||
29 | FLT1 | 2437 | 1.773 | 0.0366 | No | ||
30 | APP | 2521 | 1.730 | 0.0358 | No | ||
31 | DAZAP2 | 2607 | 1.694 | 0.0348 | No | ||
32 | SLITRK3 | 2621 | 1.685 | 0.0377 | No | ||
33 | LEFTY1 | 2636 | 1.676 | 0.0405 | No | ||
34 | CXXC6 | 2676 | 1.657 | 0.0419 | No | ||
35 | UBE2J1 | 2886 | 1.583 | 0.0339 | No | ||
36 | NPAS3 | 3001 | 1.538 | 0.0310 | No | ||
37 | RPS6KA5 | 3014 | 1.536 | 0.0336 | No | ||
38 | PPP3R1 | 3054 | 1.521 | 0.0347 | No | ||
39 | PHF6 | 3072 | 1.514 | 0.0370 | No | ||
40 | YWHAZ | 3177 | 1.476 | 0.0345 | No | ||
41 | UBE2R2 | 3206 | 1.466 | 0.0361 | No | ||
42 | EDNRB | 3286 | 1.437 | 0.0349 | No | ||
43 | OLFM3 | 3302 | 1.433 | 0.0371 | No | ||
44 | RSBN1 | 3327 | 1.421 | 0.0389 | No | ||
45 | FOXL2 | 3528 | 1.355 | 0.0309 | No | ||
46 | TRPS1 | 3544 | 1.351 | 0.0329 | No | ||
47 | CUGBP2 | 3835 | 1.266 | 0.0199 | No | ||
48 | MBNL2 | 3950 | 1.227 | 0.0163 | No | ||
49 | POLQ | 4123 | 1.180 | 0.0094 | No | ||
50 | SUV39H1 | 4210 | 1.155 | 0.0072 | No | ||
51 | ECT2 | 4229 | 1.151 | 0.0087 | No | ||
52 | INHBB | 4278 | 1.139 | 0.0085 | No | ||
53 | ZKSCAN1 | 4367 | 1.120 | 0.0061 | No | ||
54 | ZFP36L2 | 4566 | 1.070 | -0.0024 | No | ||
55 | MRPS25 | 4712 | 1.035 | -0.0080 | No | ||
56 | PLAG1 | 4719 | 1.033 | -0.0062 | No | ||
57 | PURA | 4742 | 1.026 | -0.0052 | No | ||
58 | VSX1 | 4815 | 1.011 | -0.0069 | No | ||
59 | RABEP1 | 4829 | 1.008 | -0.0055 | No | ||
60 | MMP24 | 5184 | 0.920 | -0.0228 | No | ||
61 | PRRX1 | 5245 | 0.907 | -0.0241 | No | ||
62 | LASS6 | 5249 | 0.906 | -0.0224 | No | ||
63 | NFIB | 5476 | 0.848 | -0.0328 | No | ||
64 | NEUROD1 | 6074 | 0.714 | -0.0638 | No | ||
65 | TLOC1 | 6261 | 0.675 | -0.0724 | No | ||
66 | BRP44L | 6348 | 0.656 | -0.0757 | No | ||
67 | PCDHA3 | 6380 | 0.649 | -0.0760 | No | ||
68 | MYT1L | 6477 | 0.633 | -0.0799 | No | ||
69 | ARID4A | 6489 | 0.631 | -0.0791 | No | ||
70 | ATP2B2 | 6584 | 0.612 | -0.0830 | No | ||
71 | DRD1 | 6646 | 0.599 | -0.0850 | No | ||
72 | DHX40 | 6709 | 0.588 | -0.0871 | No | ||
73 | RHOC | 6748 | 0.582 | -0.0879 | No | ||
74 | BAMBI | 7017 | 0.525 | -0.1014 | No | ||
75 | DPYSL5 | 7068 | 0.517 | -0.1030 | No | ||
76 | NEK9 | 7189 | 0.490 | -0.1085 | No | ||
77 | NEO1 | 7433 | 0.438 | -0.1208 | No | ||
78 | ST8SIA2 | 7527 | 0.418 | -0.1249 | No | ||
79 | LHX8 | 7618 | 0.403 | -0.1290 | No | ||
80 | MLLT6 | 7934 | 0.338 | -0.1454 | No | ||
81 | PCDHA10 | 8392 | 0.248 | -0.1697 | No | ||
82 | RGL1 | 8438 | 0.238 | -0.1716 | No | ||
83 | ZBTB4 | 8728 | 0.179 | -0.1870 | No | ||
84 | RAD23B | 8738 | 0.176 | -0.1871 | No | ||
85 | ARHGEF17 | 8775 | 0.169 | -0.1887 | No | ||
86 | RABGAP1 | 8866 | 0.151 | -0.1932 | No | ||
87 | CDCA7 | 8907 | 0.143 | -0.1951 | No | ||
88 | ANKRD13C | 8924 | 0.141 | -0.1957 | No | ||
89 | ZFPM2 | 9038 | 0.118 | -0.2016 | No | ||
90 | KCNMA1 | 9197 | 0.091 | -0.2100 | No | ||
91 | EPAS1 | 9335 | 0.062 | -0.2173 | No | ||
92 | TIPARP | 9409 | 0.047 | -0.2212 | No | ||
93 | BRMS1L | 9416 | 0.046 | -0.2214 | No | ||
94 | RBL1 | 9838 | -0.036 | -0.2442 | No | ||
95 | PCDHA5 | 9859 | -0.041 | -0.2452 | No | ||
96 | SENP1 | 9891 | -0.048 | -0.2468 | No | ||
97 | SLC2A4 | 9952 | -0.061 | -0.2499 | No | ||
98 | KPNA2 | 10102 | -0.091 | -0.2578 | No | ||
99 | TAOK2 | 10248 | -0.120 | -0.2654 | No | ||
100 | CCNJ | 10567 | -0.182 | -0.2823 | No | ||
101 | LHX6 | 10751 | -0.227 | -0.2918 | No | ||
102 | PCDHA11 | 10782 | -0.233 | -0.2929 | No | ||
103 | TARDBP | 10890 | -0.255 | -0.2982 | No | ||
104 | EPHA2 | 10912 | -0.259 | -0.2988 | No | ||
105 | PRDM8 | 11095 | -0.298 | -0.3081 | No | ||
106 | MEF2C | 11230 | -0.324 | -0.3147 | No | ||
107 | PCDHA12 | 11294 | -0.339 | -0.3174 | No | ||
108 | ALX4 | 11368 | -0.352 | -0.3206 | No | ||
109 | ANK2 | 11438 | -0.370 | -0.3235 | No | ||
110 | CREB5 | 11489 | -0.382 | -0.3255 | No | ||
111 | MARCH8 | 11587 | -0.402 | -0.3299 | No | ||
112 | ABCA1 | 11638 | -0.413 | -0.3317 | No | ||
113 | SSX2IP | 11899 | -0.471 | -0.3448 | No | ||
114 | WEE1 | 11945 | -0.478 | -0.3463 | No | ||
115 | SAR1B | 11946 | -0.478 | -0.3453 | No | ||
116 | MKNK2 | 12122 | -0.517 | -0.3537 | No | ||
117 | NTN4 | 12136 | -0.520 | -0.3533 | No | ||
118 | TRPV6 | 12411 | -0.582 | -0.3669 | No | ||
119 | PLEKHA3 | 12453 | -0.594 | -0.3679 | No | ||
120 | LEF1 | 12561 | -0.619 | -0.3724 | No | ||
121 | RDBP | 12584 | -0.625 | -0.3722 | No | ||
122 | ZBTB11 | 12586 | -0.625 | -0.3710 | No | ||
123 | PURB | 12592 | -0.627 | -0.3699 | No | ||
124 | MTUS1 | 12595 | -0.629 | -0.3687 | No | ||
125 | RAB11A | 12786 | -0.669 | -0.3776 | No | ||
126 | PAK7 | 12808 | -0.676 | -0.3773 | No | ||
127 | CYP26B1 | 12859 | -0.687 | -0.3785 | No | ||
128 | FGD5 | 12914 | -0.700 | -0.3800 | No | ||
129 | NR4A2 | 13020 | -0.725 | -0.3841 | No | ||
130 | OSBPL8 | 13583 | -0.869 | -0.4128 | No | ||
131 | RB1CC1 | 13588 | -0.871 | -0.4112 | No | ||
132 | E2F5 | 13649 | -0.885 | -0.4126 | No | ||
133 | RNF6 | 13890 | -0.955 | -0.4236 | No | ||
134 | MINK1 | 13903 | -0.959 | -0.4222 | No | ||
135 | GABPB2 | 13912 | -0.961 | -0.4206 | No | ||
136 | YTHDF3 | 13919 | -0.966 | -0.4189 | No | ||
137 | SF4 | 13921 | -0.966 | -0.4169 | No | ||
138 | HLF | 14103 | -1.015 | -0.4245 | No | ||
139 | VLDLR | 14126 | -1.021 | -0.4236 | No | ||
140 | ORMDL3 | 14152 | -1.031 | -0.4227 | No | ||
141 | FRMD4A | 14268 | -1.067 | -0.4267 | No | ||
142 | SPOP | 14355 | -1.090 | -0.4291 | No | ||
143 | RAB6A | 14514 | -1.140 | -0.4352 | No | ||
144 | ESR1 | 14537 | -1.146 | -0.4340 | No | ||
145 | NEUROD6 | 14869 | -1.264 | -0.4493 | No | ||
146 | RAB11FIP1 | 14908 | -1.278 | -0.4486 | No | ||
147 | PLXNA1 | 14946 | -1.293 | -0.4479 | No | ||
148 | UBE2B | 14967 | -1.301 | -0.4462 | No | ||
149 | PCAF | 15094 | -1.354 | -0.4502 | No | ||
150 | PGBD5 | 15288 | -1.437 | -0.4576 | No | ||
151 | TUSC2 | 15374 | -1.482 | -0.4591 | No | ||
152 | ETV1 | 15424 | -1.513 | -0.4585 | No | ||
153 | MTMR3 | 15468 | -1.537 | -0.4576 | No | ||
154 | MNT | 15615 | -1.616 | -0.4621 | No | ||
155 | PCDHA6 | 15627 | -1.622 | -0.4592 | No | ||
156 | PAPOLA | 15775 | -1.703 | -0.4636 | No | ||
157 | MAP3K14 | 16110 | -1.919 | -0.4776 | Yes | ||
158 | SMAD2 | 16115 | -1.921 | -0.4738 | Yes | ||
159 | PARP8 | 16124 | -1.931 | -0.4701 | Yes | ||
160 | TAL1 | 16184 | -1.973 | -0.4691 | Yes | ||
161 | KLF12 | 16230 | -2.003 | -0.4673 | Yes | ||
162 | ZMYND11 | 16341 | -2.094 | -0.4688 | Yes | ||
163 | RUNX1 | 16466 | -2.190 | -0.4709 | Yes | ||
164 | CFL2 | 16510 | -2.224 | -0.4685 | Yes | ||
165 | ZNF385 | 16544 | -2.248 | -0.4655 | Yes | ||
166 | CRIM1 | 16549 | -2.253 | -0.4609 | Yes | ||
167 | ASF1B | 16575 | -2.280 | -0.4574 | Yes | ||
168 | HIC2 | 16591 | -2.293 | -0.4533 | Yes | ||
169 | NR4A3 | 16594 | -2.296 | -0.4485 | Yes | ||
170 | DUSP2 | 16622 | -2.321 | -0.4451 | Yes | ||
171 | MECP2 | 16664 | -2.359 | -0.4423 | Yes | ||
172 | PCDHA1 | 16709 | -2.402 | -0.4395 | Yes | ||
173 | KLHL18 | 16788 | -2.487 | -0.4385 | Yes | ||
174 | NR2C2 | 16896 | -2.605 | -0.4388 | Yes | ||
175 | MAP3K11 | 16964 | -2.684 | -0.4367 | Yes | ||
176 | BCL2L11 | 17107 | -2.863 | -0.4383 | Yes | ||
177 | YPEL2 | 17115 | -2.872 | -0.4326 | Yes | ||
178 | MAPK9 | 17129 | -2.896 | -0.4271 | Yes | ||
179 | NFYA | 17146 | -2.917 | -0.4218 | Yes | ||
180 | HN1 | 17166 | -2.941 | -0.4165 | Yes | ||
181 | TMEM16F | 17212 | -3.016 | -0.4126 | Yes | ||
182 | IRF2 | 17342 | -3.221 | -0.4127 | Yes | ||
183 | WDR37 | 17351 | -3.235 | -0.4063 | Yes | ||
184 | ULK1 | 17368 | -3.262 | -0.4002 | Yes | ||
185 | RRAGD | 17496 | -3.498 | -0.3996 | Yes | ||
186 | PERQ1 | 17499 | -3.504 | -0.3923 | Yes | ||
187 | ZDHHC9 | 17503 | -3.512 | -0.3850 | Yes | ||
188 | ARHGEF10 | 17534 | -3.573 | -0.3790 | Yes | ||
189 | RAB22A | 17555 | -3.603 | -0.3724 | Yes | ||
190 | PPP6C | 17569 | -3.635 | -0.3654 | Yes | ||
191 | FOXJ2 | 17660 | -3.811 | -0.3621 | Yes | ||
192 | AEBP2 | 17747 | -3.998 | -0.3583 | Yes | ||
193 | FEM1C | 17757 | -4.026 | -0.3502 | Yes | ||
194 | WDR45 | 17762 | -4.032 | -0.3418 | Yes | ||
195 | MKRN1 | 17773 | -4.056 | -0.3337 | Yes | ||
196 | COL23A1 | 17788 | -4.076 | -0.3258 | Yes | ||
197 | PLEKHM1 | 17812 | -4.136 | -0.3183 | Yes | ||
198 | PLAGL2 | 17833 | -4.192 | -0.3104 | Yes | ||
199 | ARID4B | 17840 | -4.206 | -0.3018 | Yes | ||
200 | CREBL1 | 17856 | -4.242 | -0.2936 | Yes | ||
201 | SNF1LK | 17954 | -4.564 | -0.2891 | Yes | ||
202 | ATXN1 | 17981 | -4.640 | -0.2806 | Yes | ||
203 | IHPK1 | 18039 | -4.820 | -0.2735 | Yes | ||
204 | TOB2 | 18066 | -4.918 | -0.2644 | Yes | ||
205 | KLF13 | 18072 | -4.938 | -0.2542 | Yes | ||
206 | RASSF2 | 18078 | -4.955 | -0.2439 | Yes | ||
207 | ARHGEF18 | 18189 | -5.498 | -0.2382 | Yes | ||
208 | CCND2 | 18193 | -5.504 | -0.2266 | Yes | ||
209 | E2F7 | 18197 | -5.528 | -0.2150 | Yes | ||
210 | MCL1 | 18226 | -5.653 | -0.2045 | Yes | ||
211 | ZFYVE26 | 18259 | -5.861 | -0.1937 | Yes | ||
212 | IQWD1 | 18269 | -5.969 | -0.1815 | Yes | ||
213 | BCL11A | 18279 | -6.014 | -0.1692 | Yes | ||
214 | TOX | 18338 | -6.406 | -0.1587 | Yes | ||
215 | MAML1 | 18390 | -6.920 | -0.1467 | Yes | ||
216 | PFN2 | 18413 | -7.166 | -0.1327 | Yes | ||
217 | SS18L1 | 18420 | -7.212 | -0.1176 | Yes | ||
218 | BTG1 | 18488 | -8.254 | -0.1037 | Yes | ||
219 | BCL6 | 18521 | -9.266 | -0.0857 | Yes | ||
220 | HRBL | 18523 | -9.325 | -0.0659 | Yes | ||
221 | PHF2 | 18536 | -9.766 | -0.0457 | Yes | ||
222 | GNB5 | 18559 | -10.722 | -0.0241 | Yes | ||
223 | TLE4 | 18570 | -12.734 | 0.0025 | Yes |