Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | set03_wtNotch_versus_normalThy |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY |
| Enrichment Score (ES) | -0.729343 |
| Normalized Enrichment Score (NES) | -1.9711285 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.11453686 |
| FWER p-Value | 0.445 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CD80 | 4440 | 1.100 | -0.2186 | No | ||
| 2 | PIK3R1 | 5830 | 0.769 | -0.2792 | No | ||
| 3 | AKT1 | 6886 | 0.551 | -0.3259 | No | ||
| 4 | PDCD1 | 8428 | 0.242 | -0.4043 | No | ||
| 5 | PIK3CA | 9878 | -0.045 | -0.4814 | No | ||
| 6 | CD3D | 13681 | -0.894 | -0.6695 | No | ||
| 7 | ICOSLG | 13980 | -0.982 | -0.6675 | No | ||
| 8 | GRAP2 | 14115 | -1.018 | -0.6561 | No | ||
| 9 | CSK | 14774 | -1.225 | -0.6691 | No | ||
| 10 | PAK1 | 14871 | -1.265 | -0.6510 | No | ||
| 11 | PTPN11 | 16328 | -2.083 | -0.6912 | Yes | ||
| 12 | CD86 | 16403 | -2.142 | -0.6559 | Yes | ||
| 13 | CTLA4 | 16721 | -2.425 | -0.6286 | Yes | ||
| 14 | LCK | 16851 | -2.559 | -0.5886 | Yes | ||
| 15 | CD3G | 16861 | -2.568 | -0.5421 | Yes | ||
| 16 | VAV1 | 17585 | -3.659 | -0.5140 | Yes | ||
| 17 | MAP3K8 | 17644 | -3.789 | -0.4477 | Yes | ||
| 18 | CD4 | 17691 | -3.887 | -0.3789 | Yes | ||
| 19 | FYN | 17854 | -4.233 | -0.3101 | Yes | ||
| 20 | PDPK1 | 18265 | -5.919 | -0.2237 | Yes | ||
| 21 | CD3E | 18282 | -6.048 | -0.1138 | Yes | ||
| 22 | CD28 | 18416 | -7.191 | 0.0108 | Yes |
