Details for gene set UVC_TTD_ALL

Table: GSEA Results Summary

Dataset	set03_truncNotch_versus_wtNotch
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	UVC_TTD_ALL_DN
Enrichment Score (ES)	-0.43837762
Normalized Enrichment Score (NES)	-2.337835
Nominal p-value	0.0
FDR q-value	9.028809E-5
FWER p-Value	0.0010

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	GNAQ	64	3.955	0.0067	No
2	DLC1	109	3.570	0.0135	No
3	NUP98	169	3.340	0.0189	No
4	DUSP1	234	3.185	0.0236	No
5	MAP4K5	556	2.658	0.0130	No
6	LHFPL2	613	2.599	0.0167	No
7	HAS2	673	2.542	0.0200	No
8	IGF2BP3	965	2.304	0.0101	No
9	EGFR	1159	2.187	0.0052	No
10	ZHX3	1305	2.107	0.0028	No
11	NRG1	1392	2.072	0.0034	No
12	PEX14	1503	2.026	0.0026	No
13	FYN	1528	2.012	0.0065	No
14	PPP2R2A	1627	1.973	0.0063	No
15	ATRX	1753	1.921	0.0044	No
16	RNF13	1757	1.920	0.0092	No
17	AMPH	1896	1.863	0.0065	No
18	EXT1	2128	1.776	-0.0015	No
19	BICD1	2188	1.754	-0.0002	No
20	CREB5	2274	1.724	-0.0004	No
21	CBLB	2285	1.721	0.0035	No
22	FGF2	2313	1.711	0.0064	No
23	SMAD3	2315	1.711	0.0108	No
24	MAST2	2482	1.665	0.0061	No
25	PKP4	2513	1.659	0.0087	No
26	ATXN1	2880	1.552	-0.0072	No
27	MTMR3	2984	1.526	-0.0089	No
28	CENPE	3121	1.491	-0.0125	No
29	TLE1	3135	1.487	-0.0094	No
30	MGLL	3184	1.472	-0.0082	No
31	SRGAP2	3213	1.466	-0.0059	No
32	ANKS1A	3286	1.445	-0.0061	No
33	GULP1	3296	1.445	-0.0029	No
34	WDFY3	3640	1.369	-0.0180	No
35	HOMER1	3796	1.330	-0.0231	No
36	PTPRM	3848	1.319	-0.0224	No
37	GPR176	3901	1.305	-0.0219	No
38	MYST3	3903	1.304	-0.0186	No
39	SYNJ2	4068	1.275	-0.0242	No
40	MGAT5	4108	1.266	-0.0231	No
41	DAAM1	4252	1.235	-0.0277	No
42	ARHGEF7	4422	1.194	-0.0338	No
43	TRAM2	4467	1.185	-0.0332	No
44	INPP5F	4542	1.166	-0.0342	No
45	SERPINE1	4654	1.146	-0.0373	No
46	BHLHB2	5252	1.032	-0.0672	No
47	SLIT1	5292	1.025	-0.0666	No
48	CXCL12	5563	0.972	-0.0788	No
49	ERC1	5649	0.957	-0.0810	No
50	ARID5B	5848	0.920	-0.0894	No
51	RGS7	6140	0.866	-0.1030	No
52	MYO1B	6184	0.857	-0.1032	No
53	CD2AP	6276	0.840	-0.1060	No
54	TGFB2	6387	0.822	-0.1098	No
55	ZCCHC11	6410	0.817	-0.1089	No
56	RABGAP1L	6589	0.786	-0.1166	No
57	TSPAN5	6687	0.766	-0.1199	No
58	HIRA	6908	0.727	-0.1300	No
59	CRADD	7376	0.650	-0.1538	No
60	ACVR1	7384	0.648	-0.1525	No
61	GALK2	7389	0.648	-0.1510	No
62	EHBP1	7417	0.641	-0.1509	No
63	CDC42BPA	7458	0.634	-0.1514	No
64	CTGF	7634	0.599	-0.1594	No
65	ARHGAP12	7867	0.555	-0.1706	No
66	SKAP2	7898	0.548	-0.1708	No
67	SLC25A24	7903	0.548	-0.1696	No
68	TCF7L2	7952	0.538	-0.1709	No
69	MAD1L1	7988	0.533	-0.1714	No
70	ACVR2A	7995	0.531	-0.1703	No
71	SEMA3C	8031	0.525	-0.1709	No
72	LRIG1	8189	0.494	-0.1782	No
73	CAP2	8371	0.462	-0.1868	No
74	FARS2	8491	0.436	-0.1922	No
75	CENTG2	8569	0.422	-0.1953	No
76	NFIB	8575	0.420	-0.1945	No
77	FTO	8674	0.403	-0.1988	No
78	FGF5	8688	0.401	-0.1985	No
79	PTPN2	8723	0.395	-0.1993	No
80	GBE1	8745	0.390	-0.1994	No
81	SMURF2	8782	0.384	-0.2004	No
82	RRAS2	9117	0.319	-0.2178	No
83	TUBGCP3	9120	0.318	-0.2171	No
84	PLEKHC1	9336	0.273	-0.2281	No
85	ITSN1	9422	0.250	-0.2321	No
86	SEPT9	9569	0.218	-0.2395	No
87	EDG2	9623	0.206	-0.2418	No
88	SCHIP1	9714	0.185	-0.2462	No
89	STK39	9789	0.168	-0.2498	No
90	PRKCA	9829	0.161	-0.2516	No
91	NRIP1	9881	0.150	-0.2539	No
92	DPYD	10756	-0.041	-0.3015	No
93	FBXW11	10879	-0.066	-0.3079	No
94	ROR1	10987	-0.090	-0.3135	No
95	SLC16A7	11027	-0.100	-0.3154	No
96	CLASP2	11399	-0.184	-0.3351	No
97	ENC1	11434	-0.195	-0.3365	No
98	FBXL7	11441	-0.197	-0.3363	No
99	VEGFC	11480	-0.206	-0.3378	No
100	ARNT2	11498	-0.209	-0.3382	No
101	DDX10	11510	-0.211	-0.3383	No
102	SMAD7	11555	-0.219	-0.3401	No
103	THRAP1	11739	-0.262	-0.3494	No
104	EPHA4	11818	-0.279	-0.3529	No
105	CRY1	11974	-0.318	-0.3606	No
106	TRIM24	12170	-0.365	-0.3703	No
107	DOK5	12290	-0.393	-0.3757	No
108	TLE4	12360	-0.409	-0.3784	No
109	NCOA3	12515	-0.452	-0.3856	No
110	EVI5	12603	-0.474	-0.3892	No
111	GOLGA4	12713	-0.499	-0.3938	No
112	GNAI1	12720	-0.500	-0.3929	No
113	IFRD1	12779	-0.515	-0.3947	No
114	THRAP2	12787	-0.516	-0.3937	No
115	PRIM2A	12842	-0.531	-0.3953	No
116	ZFYVE9	12847	-0.532	-0.3942	No
117	ZHX2	12884	-0.541	-0.3947	No
118	E2F3	12935	-0.554	-0.3960	No
119	F3	13007	-0.576	-0.3984	No
120	AUH	13090	-0.600	-0.4013	No
121	SIPA1L1	13166	-0.620	-0.4038	No
122	RGS20	13203	-0.629	-0.4041	No
123	DYRK1A	13236	-0.637	-0.4042	No
124	MTF2	13249	-0.642	-0.4032	No
125	ORC2L	13315	-0.665	-0.4051	No
126	NEK7	13361	-0.680	-0.4058	No
127	IL7R	13373	-0.683	-0.4046	No
128	MITF	13381	-0.686	-0.4032	No
129	RGL1	13418	-0.695	-0.4034	No
130	CLASP1	13461	-0.707	-0.4039	No
131	ZNF148	13471	-0.708	-0.4025	No
132	KLF10	13524	-0.725	-0.4035	No
133	PHLPP	13546	-0.732	-0.4027	No
134	STARD13	13801	-0.811	-0.4145	No
135	PCTK2	13824	-0.817	-0.4136	No
136	DNMBP	13844	-0.821	-0.4125	No
137	CENPA	13875	-0.829	-0.4120	No
138	SATB2	13926	-0.842	-0.4125	No
139	BCAR3	13985	-0.860	-0.4135	No
140	MYC	14099	-0.902	-0.4173	No
141	COL5A2	14204	-0.935	-0.4206	No
142	PIP5K3	14280	-0.958	-0.4222	No
143	SHB	14297	-0.963	-0.4206	No
144	NUP153	14299	-0.964	-0.4181	No
145	ANAPC10	14310	-0.967	-0.4162	No
146	IRAK1BP1	14555	-1.041	-0.4268	No
147	LYN	14620	-1.067	-0.4275	No
148	TBL1X	14710	-1.102	-0.4295	No
149	CASP8	14812	-1.139	-0.4321	No
150	SOS1	14822	-1.141	-0.4297	No
151	PTPRK	14983	-1.203	-0.4353	Yes
152	GTF2F2	15008	-1.211	-0.4335	Yes
153	PPAP2B	15021	-1.214	-0.4310	Yes
154	TOPBP1	15048	-1.224	-0.4292	Yes
155	LASS6	15069	-1.235	-0.4271	Yes
156	PARD3	15072	-1.235	-0.4241	Yes
157	BMP2K	15147	-1.265	-0.4248	Yes
158	CASK	15148	-1.265	-0.4216	Yes
159	LARS2	15270	-1.315	-0.4248	Yes
160	SOCS5	15286	-1.320	-0.4222	Yes
161	MNAT1	15294	-1.324	-0.4192	Yes
162	SWAP70	15316	-1.331	-0.4169	Yes
163	CREBBP	15329	-1.334	-0.4141	Yes
164	GSK3B	15391	-1.361	-0.4139	Yes
165	MDN1	15474	-1.395	-0.4148	Yes
166	PBX3	15509	-1.408	-0.4130	Yes
167	KIF2A	15533	-1.417	-0.4106	Yes
168	SLC25A13	15614	-1.451	-0.4112	Yes
169	FLNB	15635	-1.459	-0.4085	Yes
170	JMJD2C	15658	-1.472	-0.4059	Yes
171	UGCG	15685	-1.484	-0.4035	Yes
172	UST	15697	-1.489	-0.4003	Yes
173	KLF7	15710	-1.494	-0.3971	Yes
174	ARFGEF1	15799	-1.532	-0.3979	Yes
175	SOCS6	15822	-1.541	-0.3952	Yes
176	SPAG9	15852	-1.558	-0.3927	Yes
177	TDRD3	15895	-1.578	-0.3909	Yes
178	PTPN12	15902	-1.580	-0.3872	Yes
179	ZMYND11	15939	-1.594	-0.3850	Yes
180	MSH3	15952	-1.600	-0.3816	Yes
181	SAMD4A	16042	-1.646	-0.3822	Yes
182	RBM16	16043	-1.646	-0.3779	Yes
183	WDHD1	16121	-1.681	-0.3778	Yes
184	MID1	16173	-1.701	-0.3762	Yes
185	CTBP2	16208	-1.718	-0.3736	Yes
186	XRCC4	16226	-1.726	-0.3701	Yes
187	MELK	16238	-1.730	-0.3662	Yes
188	FNDC3A	16264	-1.741	-0.3631	Yes
189	ATF2	16286	-1.753	-0.3597	Yes
190	ORC5L	16341	-1.784	-0.3581	Yes
191	RUNX1	16383	-1.803	-0.3556	Yes
192	STK3	16407	-1.816	-0.3522	Yes
193	LRP6	16492	-1.852	-0.3520	Yes
194	SLC4A7	16499	-1.856	-0.3475	Yes
195	MPP6	16505	-1.859	-0.3430	Yes
196	BARD1	16590	-1.904	-0.3427	Yes
197	MYST4	16623	-1.922	-0.3395	Yes
198	PPP2R5E	16688	-1.953	-0.3379	Yes
199	TCF12	16722	-1.970	-0.3346	Yes
200	MYO10	16725	-1.977	-0.3297	Yes
201	ARIH1	16744	-1.986	-0.3255	Yes
202	UBL3	16825	-2.031	-0.3246	Yes
203	NCOA1	16840	-2.036	-0.3202	Yes
204	MAPK6	16859	-2.048	-0.3159	Yes
205	CUTL1	16954	-2.094	-0.3156	Yes
206	SPOP	17008	-2.123	-0.3130	Yes
207	PPP1R12A	17014	-2.128	-0.3078	Yes
208	HNRPDL	17024	-2.135	-0.3028	Yes
209	MAP2K4	17047	-2.144	-0.2984	Yes
210	PAFAH1B1	17084	-2.165	-0.2948	Yes
211	PUM2	17116	-2.184	-0.2909	Yes
212	DAPK1	17149	-2.205	-0.2869	Yes
213	PTK2	17189	-2.224	-0.2833	Yes
214	CTAGE5	17212	-2.241	-0.2787	Yes
215	ZNF292	17383	-2.339	-0.2820	Yes
216	RBM39	17472	-2.390	-0.2806	Yes
217	CNOT4	17473	-2.390	-0.2744	Yes
218	KIF23	17511	-2.417	-0.2702	Yes
219	ZZZ3	17512	-2.418	-0.2640	Yes
220	SEC24B	17516	-2.420	-0.2579	Yes
221	FUT8	17568	-2.449	-0.2544	Yes
222	TRIM33	17582	-2.459	-0.2487	Yes
223	ATBF1	17585	-2.461	-0.2425	Yes
224	RBM6	17679	-2.526	-0.2410	Yes
225	SERPINB2	17737	-2.565	-0.2375	Yes
226	TLK1	17754	-2.574	-0.2318	Yes
227	RNGTT	17757	-2.575	-0.2252	Yes
228	STRN3	17765	-2.578	-0.2190	Yes
229	WDR7	17774	-2.584	-0.2127	Yes
230	ABI1	17790	-2.597	-0.2069	Yes
231	TLK2	17816	-2.616	-0.2015	Yes
232	MBNL1	17818	-2.617	-0.1948	Yes
233	BLM	17825	-2.619	-0.1884	Yes
234	PKN2	17845	-2.641	-0.1826	Yes
235	EIF4G3	17856	-2.652	-0.1763	Yes
236	FCHSD2	17866	-2.659	-0.1699	Yes
237	MARCH7	17877	-2.667	-0.1636	Yes
238	CNOT2	17907	-2.690	-0.1582	Yes
239	OGT	17951	-2.718	-0.1536	Yes
240	FUBP1	17981	-2.750	-0.1480	Yes
241	CDK8	17994	-2.758	-0.1416	Yes
242	STAG1	17999	-2.762	-0.1347	Yes
243	PARG	18020	-2.785	-0.1286	Yes
244	PRKACB	18025	-2.788	-0.1216	Yes
245	ITSN2	18042	-2.802	-0.1153	Yes
246	ATXN2	18057	-2.820	-0.1088	Yes
247	DHX15	18058	-2.822	-0.1015	Yes
248	AQR	18063	-2.826	-0.0944	Yes
249	ZNF638	18075	-2.833	-0.0877	Yes
250	EIF4E	18085	-2.842	-0.0809	Yes
251	ZRF1	18124	-2.885	-0.0755	Yes
252	UPF2	18242	-3.039	-0.0740	Yes
253	SRPK2	18286	-3.115	-0.0683	Yes
254	REV3L	18312	-3.147	-0.0616	Yes
255	MPHOSPH1	18370	-3.248	-0.0563	Yes
256	ROCK2	18399	-3.300	-0.0493	Yes
257	ANKRD17	18423	-3.382	-0.0419	Yes
258	CHD1	18463	-3.482	-0.0350	Yes
259	SSBP2	18492	-3.556	-0.0274	Yes
260	CCND1	18545	-3.865	-0.0202	Yes
261	CDYL	18552	-3.934	-0.0104	Yes
262	IL1RAP	18610	-5.370	0.0003	Yes