(CANONICAL)_49.png)
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | set03_absentNotch_versus_wtNotch |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | INOH_IL-1_SIGNALING(THROUGH_IKK-NFKB_CASCADE)(CANONICAL) |
| Enrichment Score (ES) | -0.52423185 |
| Normalized Enrichment Score (NES) | -1.7386314 |
| Nominal p-value | 0.007677543 |
| FDR q-value | 0.3914992 |
| FWER p-Value | 0.919 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NFKBIA | 1624 | 1.433 | -0.0351 | No | ||
| 2 | IL1A | 3004 | 1.058 | -0.0708 | No | ||
| 3 | TRAF6 | 4029 | 0.847 | -0.0950 | No | ||
| 4 | UBE2H | 4271 | 0.802 | -0.0787 | No | ||
| 5 | IRAK1 | 6123 | 0.482 | -0.1607 | No | ||
| 6 | CHUK | 6354 | 0.448 | -0.1567 | No | ||
| 7 | IL1B | 7564 | 0.276 | -0.2117 | No | ||
| 8 | MAP3K7 | 8801 | 0.083 | -0.2751 | No | ||
| 9 | NFKB1 | 9723 | -0.063 | -0.3224 | No | ||
| 10 | TOLLIP | 12550 | -0.509 | -0.4558 | No | ||
| 11 | IKBKB | 13552 | -0.685 | -0.4847 | No | ||
| 12 | IL1R1 | 14074 | -0.780 | -0.4843 | No | ||
| 13 | NFKBIB | 14397 | -0.840 | -0.4710 | No | ||
| 14 | IKBKG | 15388 | -1.054 | -0.4858 | Yes | ||
| 15 | NFKBIE | 15589 | -1.102 | -0.4565 | Yes | ||
| 16 | RELA | 15699 | -1.129 | -0.4212 | Yes | ||
| 17 | UBE2N | 15747 | -1.144 | -0.3820 | Yes | ||
| 18 | UBE2G2 | 15919 | -1.192 | -0.3478 | Yes | ||
| 19 | UBE2L3 | 16319 | -1.300 | -0.3219 | Yes | ||
| 20 | IRAK4 | 18030 | -2.104 | -0.3372 | Yes | ||
| 21 | MYD88 | 18432 | -2.673 | -0.2614 | Yes | ||
| 22 | UBE2E3 | 18521 | -3.007 | -0.1565 | Yes | ||
| 23 | IL1RAP | 18609 | -4.435 | 0.0004 | Yes |
