Details for gene set PROTEIN_KINASE

Table: GSEA Results Summary

Dataset	set03_absentNotch_versus_normalThy
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	PROTEIN_KINASE_ACTIVITY
Enrichment Score (ES)	-0.44025275
Normalized Enrichment Score (NES)	-1.6461117
Nominal p-value	0.0011273957
FDR q-value	0.6207768
FWER p-Value	1.0

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	RIPK4	17	9.178	0.0183	No
2	CSNK1D	578	3.646	-0.0046	No
3	EPHB2	726	3.367	-0.0055	No
4	CDC42BPB	755	3.314	-0.0001	No
5	MAP3K7IP1	779	3.271	0.0055	No
6	RYK	871	3.118	0.0070	No
7	MERTK	894	3.079	0.0123	No
8	MARK1	920	3.043	0.0173	No
9	MAPK10	983	2.944	0.0201	No
10	NEK4	1189	2.677	0.0145	No
11	PRKCZ	1203	2.659	0.0194	No
12	RPS6KA1	1354	2.492	0.0164	No
13	CSF1R	1457	2.392	0.0158	No
14	PDGFRA	1473	2.373	0.0200	No
15	TWF1	1643	2.236	0.0155	No
16	RPS6KA3	1863	2.086	0.0079	No
17	PDGFRB	1899	2.068	0.0103	No
18	FGFR1	1948	2.038	0.0120	No
19	TTK	2008	2.006	0.0130	No
20	MAPKAPK2	2095	1.954	0.0124	No
21	CCL2	2098	1.953	0.0164	No
22	GTF2H1	2175	1.914	0.0162	No
23	IRAK3	2179	1.913	0.0201	No
24	CHEK2	2226	1.886	0.0215	No
25	EFNA4	2227	1.886	0.0254	No
26	NRP2	2425	1.787	0.0185	No
27	EIF2AK2	2452	1.774	0.0208	No
28	STK3	2512	1.750	0.0212	No
29	FLT4	2528	1.743	0.0240	No
30	RIPK1	2636	1.696	0.0218	No
31	EPHA5	2654	1.689	0.0244	No
32	PTK7	2748	1.644	0.0227	No
33	TESK1	3157	1.487	0.0036	No
34	TYRO3	3165	1.485	0.0064	No
35	EPGN	3245	1.458	0.0051	No
36	MAPK13	3249	1.457	0.0080	No
37	MAP3K10	3326	1.427	0.0068	No
38	TTN	3638	1.316	-0.0073	No
39	PLK4	3662	1.309	-0.0058	No
40	PDK4	3826	1.260	-0.0121	No
41	IRAK1	3833	1.257	-0.0098	No
42	MAP3K13	3979	1.212	-0.0151	No
43	MAPK8	3997	1.205	-0.0135	No
44	MAP3K6	4064	1.188	-0.0147	No
45	ROR1	4171	1.160	-0.0180	No
46	MAP3K7	4229	1.146	-0.0187	No
47	NEK11	4330	1.119	-0.0218	No
48	CSNK1A1	4389	1.104	-0.0227	No
49	DAPK2	4400	1.100	-0.0209	No
50	RPS6KC1	4409	1.098	-0.0190	No
51	PDGFRL	4425	1.095	-0.0176	No
52	MAPK7	4474	1.083	-0.0179	No
53	ACVR1C	4554	1.064	-0.0200	No
54	ROCK2	4595	1.057	-0.0199	No
55	MAP2K7	4635	1.048	-0.0199	No
56	ERBB2	4752	1.016	-0.0241	No
57	ROR2	4799	1.005	-0.0245	No
58	AXL	4976	0.961	-0.0320	No
59	DDR1	5075	0.941	-0.0354	No
60	ACVR1	5221	0.905	-0.0414	No
61	STK19	5319	0.880	-0.0448	No
62	CSNK2B	5403	0.861	-0.0476	No
63	LYN	5405	0.860	-0.0458	No
64	NEK2	5414	0.859	-0.0445	No
65	DDR2	5444	0.852	-0.0442	No
66	STK38L	5605	0.820	-0.0512	No
67	CDK10	5617	0.817	-0.0501	No
68	TLK1	5802	0.779	-0.0585	No
69	VRK1	5806	0.779	-0.0571	No
70	PRKAG3	5888	0.761	-0.0599	No
71	TSSK2	5945	0.750	-0.0614	No
72	CDK9	6057	0.727	-0.0659	No
73	MAP3K9	6348	0.665	-0.0803	No
74	HUNK	6350	0.664	-0.0789	No
75	PRKCE	6499	0.633	-0.0857	No
76	DAPK3	6616	0.612	-0.0907	No
77	PRKAG1	6793	0.571	-0.0991	No
78	CHUK	6859	0.560	-0.1015	No
79	AKT1	6874	0.557	-0.1011	No
80	TIE1	6982	0.535	-0.1058	No
81	CDK7	7199	0.492	-0.1165	No
82	TAOK2	7288	0.474	-0.1203	No
83	PAK2	7318	0.467	-0.1209	No
84	EXOSC10	7379	0.456	-0.1232	No
85	ERBB4	7485	0.436	-0.1280	No
86	CDC42BPA	7689	0.399	-0.1382	No
87	LTK	7783	0.379	-0.1425	No
88	MAP3K4	7784	0.379	-0.1417	No
89	TSSK3	7824	0.371	-0.1431	No
90	NTRK1	7931	0.348	-0.1481	No
91	MAPK6	8076	0.322	-0.1553	No
92	EIF2AK1	8189	0.302	-0.1607	No
93	BCKDK	8301	0.283	-0.1662	No
94	RPS6KB2	8511	0.241	-0.1771	No
95	ACVRL1	8523	0.238	-0.1772	No
96	KDR	8623	0.216	-0.1821	No
97	SRPK2	8729	0.199	-0.1874	No
98	TEK	8819	0.185	-0.1919	No
99	ERN2	8890	0.174	-0.1953	No
100	TXK	8933	0.166	-0.1972	No
101	MAPKAPK3	8935	0.166	-0.1970	No
102	CIT	8970	0.159	-0.1985	No
103	EFNA3	9076	0.138	-0.2039	No
104	MAP2K1	9344	0.087	-0.2183	No
105	ACVR2A	9382	0.081	-0.2201	No
106	NEK6	9542	0.046	-0.2287	No
107	MET	9727	0.003	-0.2387	No
108	MAPKAPK5	9746	-0.000	-0.2397	No
109	BRSK2	9790	-0.011	-0.2420	No
110	FLT3	9819	-0.016	-0.2435	No
111	TRIB1	9842	-0.020	-0.2446	No
112	TSSK6	10013	-0.062	-0.2537	No
113	MUSK	10041	-0.067	-0.2551	No
114	RPS6KA5	10181	-0.097	-0.2624	No
115	PTK6	10202	-0.102	-0.2633	No
116	RIPK3	10247	-0.111	-0.2655	No
117	EIF2AK4	10279	-0.121	-0.2669	No
118	TSSK1A	10464	-0.160	-0.2766	No
119	TESK2	10584	-0.183	-0.2827	No
120	PRKACB	10855	-0.239	-0.2969	No
121	CCL4	11116	-0.294	-0.3104	No
122	FGFR4	11138	-0.299	-0.3109	No
123	WNK4	11154	-0.302	-0.3111	No
124	SGK2	11190	-0.309	-0.3124	No
125	STK38	11295	-0.330	-0.3174	No
126	PAK1	11346	-0.340	-0.3194	No
127	KIT	11438	-0.360	-0.3236	No
128	MKNK2	11471	-0.366	-0.3246	No
129	MYLK	11553	-0.385	-0.3282	No
130	PLK1	11717	-0.422	-0.3361	No
131	ACVR2B	11893	-0.462	-0.3447	No
132	PDK1	11983	-0.481	-0.3485	No
133	FRK	12026	-0.490	-0.3498	No
134	LIMK1	12451	-0.593	-0.3717	No
135	WNK3	12462	-0.595	-0.3710	No
136	FLT1	12483	-0.600	-0.3708	No
137	ERN1	12523	-0.609	-0.3716	No
138	MAPK4	12548	-0.616	-0.3717	No
139	PHKG2	12974	-0.721	-0.3933	No
140	BCR	12982	-0.724	-0.3921	No
141	CSNK2A2	13009	-0.730	-0.3920	No
142	MAP3K5	13494	-0.867	-0.4166	No
143	ACVR1B	13573	-0.893	-0.4190	No
144	TGFBR1	13591	-0.902	-0.4180	No
145	RPS6KA2	13596	-0.903	-0.4163	No
146	TYK2	13602	-0.905	-0.4147	No
147	PRKCB1	13692	-0.927	-0.4176	No
148	PHKA1	13712	-0.936	-0.4167	No
149	ROCK1	13717	-0.937	-0.4149	No
150	MAST1	13800	-0.962	-0.4174	No
151	ERBB3	13885	-0.989	-0.4199	No
152	TGFA	13925	-1.001	-0.4199	No
153	EFNB3	13968	-1.019	-0.4201	No
154	INSR	13977	-1.022	-0.4184	No
155	EGFR	13992	-1.027	-0.4170	No
156	STK11	14028	-1.040	-0.4167	No
157	STK16	14040	-1.045	-0.4151	No
158	CSNK2A1	14044	-1.046	-0.4131	No
159	PRKD1	14218	-1.106	-0.4202	No
160	MAP3K2	14220	-1.108	-0.4179	No
161	MST1R	14262	-1.123	-0.4178	No
162	MAPK12	14274	-1.127	-0.4161	No
163	ALK	14282	-1.130	-0.4141	No
164	IRAK2	14301	-1.134	-0.4127	No
165	HIPK3	14507	-1.208	-0.4213	No
166	MAPK14	14531	-1.214	-0.4200	No
167	MAP2K3	14582	-1.229	-0.4202	No
168	PDK3	14691	-1.273	-0.4234	No
169	CAMKK2	14810	-1.320	-0.4271	No
170	COL4A3BP	14975	-1.389	-0.4331	No
171	PRKCI	15034	-1.413	-0.4333	No
172	UHMK1	15035	-1.414	-0.4303	No
173	MKNK1	15044	-1.418	-0.4278	No
174	PBK	15193	-1.482	-0.4328	No
175	MAPK1	15209	-1.490	-0.4305	No
176	VRK2	15212	-1.492	-0.4274	No
177	TRIM27	15253	-1.514	-0.4265	No
178	MAP4K4	15416	-1.601	-0.4319	No
179	CDK2	15515	-1.650	-0.4338	No
180	CRIM1	15531	-1.657	-0.4312	No
181	CDK3	15570	-1.680	-0.4297	No
182	MAP4K5	15706	-1.757	-0.4334	No
183	CLK1	15833	-1.834	-0.4364	Yes
184	STK4	15864	-1.857	-0.4342	Yes
185	PLK3	15928	-1.897	-0.4336	Yes
186	CDKL1	15959	-1.912	-0.4313	Yes
187	NLK	16010	-1.942	-0.4299	Yes
188	LMTK2	16033	-1.960	-0.4270	Yes
189	AKT2	16083	-1.993	-0.4255	Yes
190	GSK3B	16087	-1.994	-0.4215	Yes
191	IGF1R	16151	-2.060	-0.4206	Yes
192	LATS2	16196	-2.095	-0.4186	Yes
193	ATM	16233	-2.123	-0.4162	Yes
194	MARK4	16276	-2.162	-0.4139	Yes
195	MAP4K1	16285	-2.168	-0.4098	Yes
196	TRIB2	16336	-2.218	-0.4079	Yes
197	WNK1	16341	-2.221	-0.4035	Yes
198	PRKX	16376	-2.248	-0.4006	Yes
199	PXK	16388	-2.261	-0.3965	Yes
200	EPHB6	16423	-2.290	-0.3935	Yes
201	STK17B	16471	-2.334	-0.3912	Yes
202	ILK	16520	-2.381	-0.3889	Yes
203	PRKD3	16666	-2.529	-0.3915	Yes
204	SRPK1	16686	-2.540	-0.3872	Yes
205	PRKCH	16734	-2.592	-0.3843	Yes
206	MAPK9	16893	-2.804	-0.3871	Yes
207	IGF2R	16943	-2.855	-0.3837	Yes
208	MAP4K3	16972	-2.892	-0.3792	Yes
209	CPNE3	17012	-2.943	-0.3752	Yes
210	MINK1	17042	-2.989	-0.3705	Yes
211	CSNK1G2	17052	-2.996	-0.3647	Yes
212	LIMK2	17076	-3.030	-0.3596	Yes
213	MAP3K11	17183	-3.201	-0.3587	Yes
214	MAP3K8	17204	-3.241	-0.3530	Yes
215	RIPK2	17205	-3.242	-0.3462	Yes
216	TLK2	17220	-3.268	-0.3402	Yes
217	PHKA2	17387	-3.561	-0.3418	Yes
218	CLK2	17470	-3.735	-0.3384	Yes
219	MAP2K6	17544	-3.918	-0.3342	Yes
220	TNK2	17559	-3.937	-0.3267	Yes
221	ULK1	17590	-3.987	-0.3200	Yes
222	IKBKE	17597	-3.998	-0.3120	Yes
223	PINK1	17633	-4.084	-0.3053	Yes
224	MAP3K12	17675	-4.196	-0.2988	Yes
225	EIF2AK3	17721	-4.310	-0.2922	Yes
226	CDK5	17726	-4.322	-0.2834	Yes
227	SNF1LK	17729	-4.328	-0.2744	Yes
228	MAPK11	17757	-4.401	-0.2667	Yes
229	PIM1	17761	-4.415	-0.2576	Yes
230	PIM2	17790	-4.508	-0.2497	Yes
231	ALS2CR2	17838	-4.629	-0.2426	Yes
232	CRKL	17893	-4.821	-0.2355	Yes
233	STK10	17918	-4.882	-0.2265	Yes
234	MAP3K3	18023	-5.201	-0.2213	Yes
235	CSNK1E	18048	-5.309	-0.2115	Yes
236	PDPK1	18064	-5.362	-0.2011	Yes
237	BRD2	18095	-5.480	-0.1913	Yes
238	PDK2	18108	-5.558	-0.1803	Yes
239	SNF1LK2	18208	-6.071	-0.1730	Yes
240	BRDT	18244	-6.288	-0.1618	Yes
241	ITK	18258	-6.356	-0.1492	Yes
242	DYRK1A	18283	-6.537	-0.1368	Yes
243	MARK2	18285	-6.557	-0.1231	Yes
244	SNRK	18346	-7.103	-0.1115	Yes
245	TGFBR2	18385	-7.438	-0.0980	Yes
246	SGK3	18397	-7.586	-0.0828	Yes
247	MAP4K2	18455	-8.325	-0.0685	Yes
248	CDK5R1	18501	-9.126	-0.0518	Yes
249	PTK2B	18534	-10.458	-0.0317	Yes
250	TEC	18590	-17.252	0.0014	Yes