Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | set03_absentNotch_versus_normalThy |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_neg |
| GeneSet | REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY |
| Enrichment Score (ES) | -0.7245818 |
| Normalized Enrichment Score (NES) | -1.8897431 |
| Nominal p-value | 0.0016420361 |
| FDR q-value | 0.089991026 |
| FWER p-Value | 0.643 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CD80 | 2053 | 1.981 | -0.0781 | No | ||
| 2 | PIK3R1 | 6233 | 0.693 | -0.2915 | No | ||
| 3 | GRAP2 | 6593 | 0.616 | -0.3007 | No | ||
| 4 | CD86 | 6605 | 0.614 | -0.2913 | No | ||
| 5 | AKT1 | 6874 | 0.557 | -0.2966 | No | ||
| 6 | PDCD1 | 9632 | 0.024 | -0.4445 | No | ||
| 7 | PAK1 | 11346 | -0.340 | -0.5310 | No | ||
| 8 | ICOSLG | 13763 | -0.951 | -0.6454 | No | ||
| 9 | PIK3CA | 14498 | -1.205 | -0.6652 | No | ||
| 10 | PTPN11 | 15185 | -1.479 | -0.6779 | No | ||
| 11 | CTLA4 | 15398 | -1.593 | -0.6633 | No | ||
| 12 | CSK | 16538 | -2.400 | -0.6854 | Yes | ||
| 13 | CD3D | 16927 | -2.841 | -0.6598 | Yes | ||
| 14 | MAP3K8 | 17204 | -3.241 | -0.6217 | Yes | ||
| 15 | LCK | 17279 | -3.355 | -0.5709 | Yes | ||
| 16 | CD3G | 17824 | -4.591 | -0.5252 | Yes | ||
| 17 | CD4 | 17903 | -4.846 | -0.4502 | Yes | ||
| 18 | VAV1 | 17943 | -4.944 | -0.3716 | Yes | ||
| 19 | FYN | 18056 | -5.334 | -0.2905 | Yes | ||
| 20 | PDPK1 | 18064 | -5.362 | -0.2033 | Yes | ||
| 21 | CD28 | 18291 | -6.622 | -0.1073 | Yes | ||
| 22 | CD3E | 18405 | -7.633 | 0.0113 | Yes |
