Dataset | Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB |
Phenotype | phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB |
Upregulated in class | transDMpreB |
GeneSet | V$E2F_Q4_01 |
Enrichment Score (ES) | 0.54811 |
Normalized Enrichment Score (NES) | 1.4033853 |
Nominal p-value | 0.007889546 |
FDR q-value | 0.2966613 |
FWER p-Value | 0.998 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | IMPDH2 | 10730 | 69 | 7.844 | 0.0323 | Yes | ||
2 | EIF5A | 11345 20379 6590 | 125 | 6.952 | 0.0612 | Yes | ||
3 | KPNB1 | 20274 | 202 | 6.157 | 0.0854 | Yes | ||
4 | CDCA7 | 12437 | 210 | 6.035 | 0.1127 | Yes | ||
5 | UNG | 10257 16744 | 232 | 5.883 | 0.1386 | Yes | ||
6 | PPRC1 | 23808 | 260 | 5.666 | 0.1631 | Yes | ||
7 | MCM3 | 13991 | 372 | 4.986 | 0.1800 | Yes | ||
8 | POLA2 | 23988 | 396 | 4.885 | 0.2012 | Yes | ||
9 | CDC25A | 8721 | 411 | 4.833 | 0.2226 | Yes | ||
10 | MCM2 | 17074 | 445 | 4.703 | 0.2424 | Yes | ||
11 | KNTC1 | 16705 | 613 | 3.996 | 0.2517 | Yes | ||
12 | ACBD6 | 14089 | 621 | 3.968 | 0.2696 | Yes | ||
13 | DNMT1 | 19217 | 641 | 3.927 | 0.2866 | Yes | ||
14 | PIK3R3 | 5248 | 656 | 3.876 | 0.3036 | Yes | ||
15 | ATP5G2 | 12610 | 681 | 3.781 | 0.3197 | Yes | ||
16 | RFC1 | 16527 | 696 | 3.717 | 0.3360 | Yes | ||
17 | HMGA1 | 23323 | 710 | 3.664 | 0.3521 | Yes | ||
18 | PRIM1 | 19847 | 719 | 3.648 | 0.3684 | Yes | ||
19 | GMNN | 21513 | 749 | 3.568 | 0.3832 | Yes | ||
20 | APRIN | 4145 | 758 | 3.550 | 0.3991 | Yes | ||
21 | NUTF2 | 12632 7529 | 781 | 3.496 | 0.4139 | Yes | ||
22 | IPO11 | 21353 | 804 | 3.423 | 0.4285 | Yes | ||
23 | SYT11 | 15285 | 927 | 3.079 | 0.4360 | Yes | ||
24 | TIAM1 | 22547 | 969 | 2.969 | 0.4474 | Yes | ||
25 | PCNA | 9535 | 1127 | 2.676 | 0.4512 | Yes | ||
26 | RPS19 | 5398 | 1168 | 2.594 | 0.4609 | Yes | ||
27 | NCL | 5153 13899 | 1212 | 2.514 | 0.4701 | Yes | ||
28 | NASP | 2383 2387 6955 | 1225 | 2.494 | 0.4809 | Yes | ||
29 | PIK3R4 | 19333 | 1235 | 2.484 | 0.4918 | Yes | ||
30 | DLST | 8131 | 1408 | 2.221 | 0.4927 | Yes | ||
31 | SUV39H1 | 24194 | 1410 | 2.217 | 0.5029 | Yes | ||
32 | YWHAQ | 10369 | 1436 | 2.169 | 0.5115 | Yes | ||
33 | MCM7 | 9372 3568 | 1539 | 1.995 | 0.5151 | Yes | ||
34 | PPP1R8 | 15730 | 1579 | 1.937 | 0.5219 | Yes | ||
35 | SFRS1 | 8492 | 1857 | 1.596 | 0.5142 | Yes | ||
36 | STMN1 | 9261 | 1957 | 1.452 | 0.5155 | Yes | ||
37 | E2F1 | 14384 | 1966 | 1.442 | 0.5217 | Yes | ||
38 | E2F7 | 19884 | 2086 | 1.299 | 0.5212 | Yes | ||
39 | ZCCHC8 | 3570 7696 | 2131 | 1.233 | 0.5245 | Yes | ||
40 | DNAJC11 | 2486 6068 | 2135 | 1.231 | 0.5300 | Yes | ||
41 | BRMS1L | 21268 | 2183 | 1.179 | 0.5328 | Yes | ||
42 | MELK | 2453 16227 | 2190 | 1.167 | 0.5379 | Yes | ||
43 | SFMBT1 | 12053 7050 | 2221 | 1.132 | 0.5414 | Yes | ||
44 | SFRS2 | 9807 20136 | 2224 | 1.131 | 0.5465 | Yes | ||
45 | E2F3 | 21500 8874 | 2288 | 1.048 | 0.5479 | Yes | ||
46 | TOP1 | 5790 5789 10210 | 2370 | 0.996 | 0.5481 | Yes | ||
47 | HTF9C | 4886 1678 | 2513 | 0.889 | 0.5445 | No | ||
48 | FANCC | 4712 | 2538 | 0.873 | 0.5472 | No | ||
49 | DAXX | 23290 | 2666 | 0.773 | 0.5439 | No | ||
50 | PTMA | 9657 | 2914 | 0.576 | 0.5331 | No | ||
51 | USP52 | 3397 19841 | 3056 | 0.489 | 0.5277 | No | ||
52 | PRKDC | 9617 22847 | 3126 | 0.448 | 0.5261 | No | ||
53 | ASXL2 | 7957 | 3193 | 0.413 | 0.5244 | No | ||
54 | USP2 | 19480 3052 3043 | 3489 | 0.303 | 0.5098 | No | ||
55 | WEE1 | 18127 | 3500 | 0.297 | 0.5106 | No | ||
56 | SLC38A1 | 22148 | 3837 | 0.221 | 0.4934 | No | ||
57 | DDB2 | 2721 2878 14525 2661 | 3844 | 0.219 | 0.4941 | No | ||
58 | TNPO2 | 5608 | 3852 | 0.218 | 0.4947 | No | ||
59 | MAZ | 1327 17623 | 3902 | 0.209 | 0.4930 | No | ||
60 | SALL1 | 18796 12207 | 4007 | 0.191 | 0.4883 | No | ||
61 | CDC6 | 6221 6220 | 4074 | 0.180 | 0.4855 | No | ||
62 | PAQR4 | 23105 | 4278 | 0.155 | 0.4753 | No | ||
63 | TNFRSF19L | 11498 6727 6726 | 4306 | 0.152 | 0.4745 | No | ||
64 | NCOA6 | 2876 14382 | 4372 | 0.144 | 0.4716 | No | ||
65 | KCND2 | 4941 17515 | 4544 | 0.127 | 0.4629 | No | ||
66 | FBXO5 | 19830 | 4774 | 0.111 | 0.4510 | No | ||
67 | SLC6A4 | 20770 | 4846 | 0.107 | 0.4477 | No | ||
68 | KCNA6 | 664 16990 665 4938 | 5006 | 0.096 | 0.4395 | No | ||
69 | RAD51 | 2897 14903 | 5044 | 0.094 | 0.4379 | No | ||
70 | NEGR1 | 6806 11572 | 5109 | 0.090 | 0.4349 | No | ||
71 | DPYSL2 | 3122 4561 8787 | 5276 | 0.082 | 0.4263 | No | ||
72 | PHF15 | 20467 8050 | 5278 | 0.082 | 0.4266 | No | ||
73 | PVRL1 | 3006 19482 12211 7192 | 5564 | 0.069 | 0.4115 | No | ||
74 | PCDH7 | 7029 3460 | 5693 | 0.065 | 0.4048 | No | ||
75 | FANCG | 15904 | 5732 | 0.063 | 0.4031 | No | ||
76 | RANBP1 | 9692 5357 | 5788 | 0.062 | 0.4004 | No | ||
77 | YBX2 | 20818 | 5844 | 0.060 | 0.3977 | No | ||
78 | ARID4A | 2080 6215 | 5853 | 0.060 | 0.3975 | No | ||
79 | GLRA3 | 18617 | 5865 | 0.060 | 0.3972 | No | ||
80 | ATAD2 | 2268 2256 | 6038 | 0.055 | 0.3881 | No | ||
81 | CITED2 | 5118 14477 | 6507 | 0.044 | 0.3630 | No | ||
82 | CDC45L | 22642 1752 | 6568 | 0.043 | 0.3599 | No | ||
83 | IPO7 | 6130 | 6750 | 0.039 | 0.3503 | No | ||
84 | NR3C2 | 18562 13798 | 6899 | 0.037 | 0.3424 | No | ||
85 | EPHB2 | 4675 2440 8910 | 6902 | 0.037 | 0.3425 | No | ||
86 | STAG1 | 5520 9905 2987 | 7002 | 0.035 | 0.3373 | No | ||
87 | SLBP | 9822 | 7052 | 0.034 | 0.3348 | No | ||
88 | POLE2 | 21053 | 7814 | 0.022 | 0.2937 | No | ||
89 | HOXC10 | 22342 | 8430 | 0.014 | 0.2604 | No | ||
90 | PODN | 15811 | 8681 | 0.010 | 0.2469 | No | ||
91 | ADAMTS2 | 5706 20899 1356 | 8974 | 0.007 | 0.2311 | No | ||
92 | ERBB2IP | 3232 12234 | 9066 | 0.006 | 0.2262 | No | ||
93 | HNRPD | 8645 | 9217 | 0.004 | 0.2181 | No | ||
94 | FMO4 | 13786 | 9538 | -0.001 | 0.2008 | No | ||
95 | MAP3K13 | 22814 | 9607 | -0.002 | 0.1971 | No | ||
96 | ERG | 1686 8915 | 9637 | -0.002 | 0.1955 | No | ||
97 | LUC7L2 | 5313 5312 | 9796 | -0.004 | 0.1870 | No | ||
98 | RPS6KA5 | 2076 21005 | 10489 | -0.013 | 0.1496 | No | ||
99 | DCLRE1A | 23641 | 10531 | -0.013 | 0.1474 | No | ||
100 | TOPBP1 | 10659 | 10535 | -0.013 | 0.1473 | No | ||
101 | PLK4 | 1870 1874 | 10808 | -0.017 | 0.1326 | No | ||
102 | EPHB1 | 19024 | 10967 | -0.019 | 0.1242 | No | ||
103 | CASP2 | 8692 | 11132 | -0.022 | 0.1154 | No | ||
104 | BAI1 | 22459 | 11136 | -0.022 | 0.1153 | No | ||
105 | CASP8AP2 | 16253 | 11427 | -0.026 | 0.0997 | No | ||
106 | CBX5 | 22108 4485 | 11481 | -0.027 | 0.0970 | No | ||
107 | HIST1H1D | 4821 | 11701 | -0.031 | 0.0853 | No | ||
108 | GATA3 | 9004 | 11848 | -0.033 | 0.0775 | No | ||
109 | NRP2 | 5194 9486 5195 | 12056 | -0.037 | 0.0665 | No | ||
110 | RNF121 | 7952 373 | 12101 | -0.038 | 0.0642 | No | ||
111 | UXT | 5837 10267 | 12294 | -0.042 | 0.0540 | No | ||
112 | BMP7 | 14324 | 12558 | -0.049 | 0.0400 | No | ||
113 | EZH2 | 1092 17163 | 12641 | -0.051 | 0.0358 | No | ||
114 | AP1S2 | 8423 4228 | 13050 | -0.063 | 0.0140 | No | ||
115 | PEG3 | 5240 | 13230 | -0.069 | 0.0046 | No | ||
116 | DIO3 | 19359 | 13732 | -0.094 | -0.0221 | No | ||
117 | PCSK4 | 19696 3296 3394 18705 | 14045 | -0.114 | -0.0385 | No | ||
118 | GPRC5B | 17662 | 14187 | -0.126 | -0.0455 | No | ||
119 | SLC16A2 | 24086 | 14364 | -0.141 | -0.0544 | No | ||
120 | SEMA5A | 22496 5423 | 14424 | -0.149 | -0.0569 | No | ||
121 | HOXA9 | 17147 9109 1024 | 14451 | -0.152 | -0.0576 | No | ||
122 | RBBP4 | 5364 | 14541 | -0.161 | -0.0617 | No | ||
123 | KLF5 | 4456 | 14608 | -0.169 | -0.0645 | No | ||
124 | UCHL1 | 16834 | 14716 | -0.186 | -0.0695 | No | ||
125 | DMD | 24295 2647 | 14880 | -0.212 | -0.0773 | No | ||
126 | ERF | 4680 8914 | 14929 | -0.222 | -0.0789 | No | ||
127 | MYC | 22465 9435 | 14983 | -0.233 | -0.0807 | No | ||
128 | TBX3 | 16723 | 15109 | -0.260 | -0.0863 | No | ||
129 | DMRT1 | 23899 | 15140 | -0.265 | -0.0867 | No | ||
130 | GPS2 | 12096 | 15533 | -0.395 | -0.1061 | No | ||
131 | JPH1 | 13994 | 15590 | -0.417 | -0.1072 | No | ||
132 | ETV4 | 20212 | 15598 | -0.419 | -0.1057 | No | ||
133 | AP4M1 | 3499 16656 | 15643 | -0.438 | -0.1061 | No | ||
134 | MCM6 | 4000 13845 4119 | 15750 | -0.489 | -0.1096 | No | ||
135 | ORC1L | 327 16144 | 15769 | -0.497 | -0.1083 | No | ||
136 | HMGN2 | 9095 | 16119 | -0.766 | -0.1236 | No | ||
137 | H2AFZ | 6957 | 16123 | -0.772 | -0.1203 | No | ||
138 | STAG2 | 5521 | 16249 | -0.911 | -0.1229 | No | ||
139 | HNRPA1 | 9103 4860 | 16351 | -0.999 | -0.1237 | No | ||
140 | MCM4 | 22655 1708 | 16371 | -1.005 | -0.1202 | No | ||
141 | ANP32E | 15500 | 16431 | -1.052 | -0.1185 | No | ||
142 | UFD1L | 22825 | 16472 | -1.090 | -0.1157 | No | ||
143 | ABCF2 | 11338 6580 6579 | 16794 | -1.501 | -0.1262 | No | ||
144 | CTCF | 18490 | 16806 | -1.517 | -0.1198 | No | ||
145 | MAP4K1 | 18313 | 16826 | -1.546 | -0.1137 | No | ||
146 | ATE1 | 388 17602 | 16885 | -1.644 | -0.1093 | No | ||
147 | HRBL | 3452 16326 3614 | 16951 | -1.729 | -0.1049 | No | ||
148 | NHLRC2 | 23828 | 16979 | -1.757 | -0.0983 | No | ||
149 | NDUFA11 | 12832 | 17128 | -1.999 | -0.0972 | No | ||
150 | MAT2A | 10553 10554 6099 | 17155 | -2.051 | -0.0891 | No | ||
151 | FBXL20 | 13010 | 17370 | -2.421 | -0.0896 | No | ||
152 | POLE4 | 12441 | 17502 | -2.639 | -0.0846 | No | ||
153 | AXUD1 | 18967 | 17650 | -2.946 | -0.0790 | No | ||
154 | RAB11B | 9676 | 17913 | -3.710 | -0.0762 | No | ||
155 | PPP1R9B | 20698 | 18139 | -4.519 | -0.0676 | No | ||
156 | DCK | 16808 | 18181 | -4.761 | -0.0480 | No | ||
157 | PPM1D | 20721 | 18221 | -4.979 | -0.0273 | No | ||
158 | FBXO9 | 19058 3146 | 18243 | -5.084 | -0.0050 | No | ||
159 | MXD3 | 21455 | 18327 | -5.489 | 0.0157 | No |