Dataset | Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB |
Phenotype | phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB |
Upregulated in class | transDMpreB |
GeneSet | V$E2F1_Q6_01 |
Enrichment Score (ES) | 0.58776784 |
Normalized Enrichment Score (NES) | 1.4905951 |
Nominal p-value | 0.0019230769 |
FDR q-value | 0.80493575 |
FWER p-Value | 0.845 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | CDCA7 | 12437 | 210 | 6.035 | 0.0187 | Yes | ||
2 | UNG | 10257 16744 | 232 | 5.883 | 0.0468 | Yes | ||
3 | PPRC1 | 23808 | 260 | 5.666 | 0.0735 | Yes | ||
4 | FKBP5 | 23051 | 329 | 5.237 | 0.0959 | Yes | ||
5 | GSPT1 | 9046 | 357 | 5.076 | 0.1197 | Yes | ||
6 | MCM3 | 13991 | 372 | 4.986 | 0.1438 | Yes | ||
7 | POLA2 | 23988 | 396 | 4.885 | 0.1669 | Yes | ||
8 | RQCD1 | 12205 | 397 | 4.875 | 0.1911 | Yes | ||
9 | CDC25A | 8721 | 411 | 4.833 | 0.2145 | Yes | ||
10 | MCM2 | 17074 | 445 | 4.703 | 0.2361 | Yes | ||
11 | MSH2 | 23138 | 583 | 4.074 | 0.2490 | Yes | ||
12 | ACBD6 | 14089 | 621 | 3.968 | 0.2667 | Yes | ||
13 | PHF5A | 22194 | 627 | 3.958 | 0.2861 | Yes | ||
14 | DNMT1 | 19217 | 641 | 3.927 | 0.3050 | Yes | ||
15 | ATP5G2 | 12610 | 681 | 3.781 | 0.3217 | Yes | ||
16 | NOLC1 | 7704 | 728 | 3.609 | 0.3371 | Yes | ||
17 | POLD3 | 17742 | 746 | 3.578 | 0.3540 | Yes | ||
18 | GMNN | 21513 | 749 | 3.568 | 0.3717 | Yes | ||
19 | PRPS1 | 24233 | 811 | 3.405 | 0.3853 | Yes | ||
20 | HIRA | 4852 9090 | 979 | 2.952 | 0.3910 | Yes | ||
21 | ACO2 | 8527 | 984 | 2.941 | 0.4054 | Yes | ||
22 | MRPL40 | 22641 | 993 | 2.919 | 0.4195 | Yes | ||
23 | PCNA | 9535 | 1127 | 2.676 | 0.4256 | Yes | ||
24 | RPS19 | 5398 | 1168 | 2.594 | 0.4363 | Yes | ||
25 | NCL | 5153 13899 | 1212 | 2.514 | 0.4465 | Yes | ||
26 | NASP | 2383 2387 6955 | 1225 | 2.494 | 0.4583 | Yes | ||
27 | ILF3 | 3110 3030 9176 | 1240 | 2.476 | 0.4699 | Yes | ||
28 | EED | 17759 | 1249 | 2.461 | 0.4817 | Yes | ||
29 | AP1S1 | 3500 3453 16335 | 1306 | 2.379 | 0.4905 | Yes | ||
30 | SUMO1 | 5826 3943 10247 | 1350 | 2.328 | 0.4997 | Yes | ||
31 | SUV39H1 | 24194 | 1410 | 2.217 | 0.5076 | Yes | ||
32 | MCM7 | 9372 3568 | 1539 | 1.995 | 0.5106 | Yes | ||
33 | INSM1 | 14815 | 1550 | 1.979 | 0.5199 | Yes | ||
34 | PPP1R8 | 15730 | 1579 | 1.937 | 0.5280 | Yes | ||
35 | NUMA1 | 18167 | 1683 | 1.789 | 0.5313 | Yes | ||
36 | SIN3A | 5442 | 1765 | 1.683 | 0.5353 | Yes | ||
37 | AMD1 | 8583 | 1828 | 1.623 | 0.5400 | Yes | ||
38 | SFRS1 | 8492 | 1857 | 1.596 | 0.5465 | Yes | ||
39 | CLSPN | 16079 11256 6530 | 1890 | 1.549 | 0.5524 | Yes | ||
40 | SYNCRIP | 3078 3035 3107 | 1899 | 1.539 | 0.5597 | Yes | ||
41 | STMN1 | 9261 | 1957 | 1.452 | 0.5638 | Yes | ||
42 | E2F1 | 14384 | 1966 | 1.442 | 0.5705 | Yes | ||
43 | DNAJC11 | 2486 6068 | 2135 | 1.231 | 0.5676 | Yes | ||
44 | USP37 | 13923 | 2155 | 1.208 | 0.5726 | Yes | ||
45 | BRMS1L | 21268 | 2183 | 1.179 | 0.5770 | Yes | ||
46 | SFRS2 | 9807 20136 | 2224 | 1.131 | 0.5804 | Yes | ||
47 | SLC25A1 | 22645 | 2243 | 1.101 | 0.5849 | Yes | ||
48 | E2F3 | 21500 8874 | 2288 | 1.048 | 0.5878 | Yes | ||
49 | HTF9C | 4886 1678 | 2513 | 0.889 | 0.5801 | No | ||
50 | FHOD1 | 18772 | 2527 | 0.882 | 0.5837 | No | ||
51 | FANCC | 4712 | 2538 | 0.873 | 0.5876 | No | ||
52 | TRIM39 | 22994 | 2667 | 0.772 | 0.5845 | No | ||
53 | PTMA | 9657 | 2914 | 0.576 | 0.5740 | No | ||
54 | CDC5L | 7746 7745 7744 | 2952 | 0.557 | 0.5748 | No | ||
55 | USP52 | 3397 19841 | 3056 | 0.489 | 0.5716 | No | ||
56 | PRKDC | 9617 22847 | 3126 | 0.448 | 0.5701 | No | ||
57 | ASXL2 | 7957 | 3193 | 0.413 | 0.5686 | No | ||
58 | GATA1 | 24196 | 3313 | 0.366 | 0.5640 | No | ||
59 | USP2 | 19480 3052 3043 | 3489 | 0.303 | 0.5560 | No | ||
60 | WEE1 | 18127 | 3500 | 0.297 | 0.5569 | No | ||
61 | DDB2 | 2721 2878 14525 2661 | 3844 | 0.219 | 0.5394 | No | ||
62 | MAZ | 1327 17623 | 3902 | 0.209 | 0.5374 | No | ||
63 | PAQR4 | 23105 | 4278 | 0.155 | 0.5178 | No | ||
64 | TNFRSF19L | 11498 6727 6726 | 4306 | 0.152 | 0.5171 | No | ||
65 | NCOA6 | 2876 14382 | 4372 | 0.144 | 0.5143 | No | ||
66 | HMGA2 | 4857 9098 3341 3444 | 4472 | 0.135 | 0.5096 | No | ||
67 | CNOT3 | 6112 10565 6113 | 4478 | 0.134 | 0.5100 | No | ||
68 | HR | 3622 9119 | 4597 | 0.124 | 0.5043 | No | ||
69 | FAF1 | 2508 16137 8951 | 4726 | 0.114 | 0.4979 | No | ||
70 | FBXO5 | 19830 | 4774 | 0.111 | 0.4959 | No | ||
71 | RAD51 | 2897 14903 | 5044 | 0.094 | 0.4818 | No | ||
72 | RPL18 | 450 5390 | 5252 | 0.083 | 0.4710 | No | ||
73 | PHF15 | 20467 8050 | 5278 | 0.082 | 0.4700 | No | ||
74 | REPS2 | 24018 | 5571 | 0.069 | 0.4546 | No | ||
75 | SYT6 | 13437 7042 12040 | 5616 | 0.067 | 0.4525 | No | ||
76 | FANCG | 15904 | 5732 | 0.063 | 0.4466 | No | ||
77 | RANBP1 | 9692 5357 | 5788 | 0.062 | 0.4439 | No | ||
78 | YBX2 | 20818 | 5844 | 0.060 | 0.4413 | No | ||
79 | HNRPUL1 | 6118 17923 1608 10577 1345 | 5894 | 0.059 | 0.4389 | No | ||
80 | ATAD2 | 2268 2256 | 6038 | 0.055 | 0.4314 | No | ||
81 | CDC45L | 22642 1752 | 6568 | 0.043 | 0.4030 | No | ||
82 | IPO7 | 6130 | 6750 | 0.039 | 0.3934 | No | ||
83 | STAG1 | 5520 9905 2987 | 7002 | 0.035 | 0.3799 | No | ||
84 | KCNS2 | 4949 2232 | 7006 | 0.035 | 0.3799 | No | ||
85 | MYH10 | 8077 | 7677 | 0.024 | 0.3438 | No | ||
86 | STK35 | 14851 | 7678 | 0.024 | 0.3439 | No | ||
87 | POLE2 | 21053 | 7814 | 0.022 | 0.3367 | No | ||
88 | PCSK1 | 21600 | 8125 | 0.018 | 0.3200 | No | ||
89 | NPAT | 19452 6356 | 8266 | 0.016 | 0.3125 | No | ||
90 | HOXC10 | 22342 | 8430 | 0.014 | 0.3037 | No | ||
91 | PODN | 15811 | 8681 | 0.010 | 0.2902 | No | ||
92 | PCDH10 | 5227 9534 1893 | 8692 | 0.010 | 0.2897 | No | ||
93 | TYRO3 | 5811 | 8858 | 0.008 | 0.2808 | No | ||
94 | ADAMTS2 | 5706 20899 1356 | 8974 | 0.007 | 0.2746 | No | ||
95 | ERBB2IP | 3232 12234 | 9066 | 0.006 | 0.2697 | No | ||
96 | ATM | 2976 19115 | 9162 | 0.004 | 0.2646 | No | ||
97 | HNRPD | 8645 | 9217 | 0.004 | 0.2617 | No | ||
98 | DNAJC9 | 21912 | 9225 | 0.004 | 0.2613 | No | ||
99 | RB1CC1 | 4486 14299 | 9427 | 0.001 | 0.2504 | No | ||
100 | FZD1 | 16923 | 9429 | 0.001 | 0.2504 | No | ||
101 | BMP2 | 14833 | 9957 | -0.006 | 0.2219 | No | ||
102 | IRX3 | 18793 | 9965 | -0.006 | 0.2215 | No | ||
103 | PAX6 | 5223 | 10181 | -0.009 | 0.2099 | No | ||
104 | MTSS1 | 5585 22285 | 10467 | -0.013 | 0.1945 | No | ||
105 | DHH | 4629 | 10519 | -0.013 | 0.1918 | No | ||
106 | TOPBP1 | 10659 | 10535 | -0.013 | 0.1911 | No | ||
107 | CASP2 | 8692 | 11132 | -0.022 | 0.1589 | No | ||
108 | SPHK2 | 1217 1806 12155 | 11209 | -0.023 | 0.1549 | No | ||
109 | CASP8AP2 | 16253 | 11427 | -0.026 | 0.1433 | No | ||
110 | CBX5 | 22108 4485 | 11481 | -0.027 | 0.1406 | No | ||
111 | HCN3 | 4843 1763 | 11507 | -0.027 | 0.1393 | No | ||
112 | GNG4 | 21706 | 11518 | -0.027 | 0.1389 | No | ||
113 | UXT | 5837 10267 | 12294 | -0.042 | 0.0972 | No | ||
114 | EZH2 | 1092 17163 | 12641 | -0.051 | 0.0787 | No | ||
115 | TNF | 23004 | 12665 | -0.052 | 0.0777 | No | ||
116 | TBX6 | 1993 18075 | 12826 | -0.056 | 0.0693 | No | ||
117 | MGAT2 | 21256 | 12855 | -0.056 | 0.0680 | No | ||
118 | ARHGAP6 | 24207 | 12930 | -0.059 | 0.0643 | No | ||
119 | SYNGR4 | 17825 | 13769 | -0.095 | 0.0194 | No | ||
120 | HNRPR | 13196 7909 2500 | 13785 | -0.096 | 0.0191 | No | ||
121 | GPRC5B | 17662 | 14187 | -0.126 | -0.0020 | No | ||
122 | RBL1 | 14373 | 14231 | -0.130 | -0.0037 | No | ||
123 | MCM8 | 14834 | 14591 | -0.168 | -0.0223 | No | ||
124 | KLF5 | 4456 | 14608 | -0.169 | -0.0223 | No | ||
125 | ACTN3 | 23967 8540 | 14793 | -0.197 | -0.0313 | No | ||
126 | ERF | 4680 8914 | 14929 | -0.222 | -0.0375 | No | ||
127 | POU2F1 | 5275 3989 4065 4010 | 14949 | -0.225 | -0.0375 | No | ||
128 | MYC | 22465 9435 | 14983 | -0.233 | -0.0381 | No | ||
129 | SP1 | 9852 | 15042 | -0.246 | -0.0400 | No | ||
130 | SMARCA1 | 24165 | 15241 | -0.291 | -0.0493 | No | ||
131 | EFNA5 | 4655 8884 | 15319 | -0.314 | -0.0519 | No | ||
132 | CCNT1 | 22140 11607 | 15392 | -0.339 | -0.0541 | No | ||
133 | LRP1 | 9284 | 15456 | -0.363 | -0.0557 | No | ||
134 | JPH1 | 13994 | 15590 | -0.417 | -0.0608 | No | ||
135 | AP4M1 | 3499 16656 | 15643 | -0.438 | -0.0615 | No | ||
136 | MCM6 | 4000 13845 4119 | 15750 | -0.489 | -0.0648 | No | ||
137 | ORC1L | 327 16144 | 15769 | -0.497 | -0.0633 | No | ||
138 | ENPP1 | 19804 | 15800 | -0.517 | -0.0623 | No | ||
139 | PHF13 | 15659 | 15802 | -0.519 | -0.0598 | No | ||
140 | HMGN2 | 9095 | 16119 | -0.766 | -0.0731 | No | ||
141 | TMPO | 5778 | 16191 | -0.856 | -0.0727 | No | ||
142 | STAG2 | 5521 | 16249 | -0.911 | -0.0712 | No | ||
143 | HNRPA1 | 9103 4860 | 16351 | -0.999 | -0.0717 | No | ||
144 | MCM4 | 22655 1708 | 16371 | -1.005 | -0.0678 | No | ||
145 | CHD4 | 8418 17281 4225 | 16459 | -1.079 | -0.0671 | No | ||
146 | UFD1L | 22825 | 16472 | -1.090 | -0.0623 | No | ||
147 | PIK3CD | 9563 | 16667 | -1.326 | -0.0662 | No | ||
148 | CTCF | 18490 | 16806 | -1.517 | -0.0662 | No | ||
149 | HIST1H2AH | 11414 | 16813 | -1.529 | -0.0589 | No | ||
150 | MAP4K1 | 18313 | 16826 | -1.546 | -0.0518 | No | ||
151 | GADD45B | 19935 | 16872 | -1.620 | -0.0462 | No | ||
152 | ATE1 | 388 17602 | 16885 | -1.644 | -0.0387 | No | ||
153 | AK2 | 8563 2479 16073 | 16931 | -1.712 | -0.0326 | No | ||
154 | SLC9A7 | 24177 | 17097 | -1.949 | -0.0318 | No | ||
155 | HIST1H2BK | 11423 | 17527 | -2.689 | -0.0417 | No | ||
156 | RAB11B | 9676 | 17913 | -3.710 | -0.0441 | No | ||
157 | PPM1D | 20721 | 18221 | -4.979 | -0.0359 | No | ||
158 | MXD3 | 21455 | 18327 | -5.489 | -0.0143 | No | ||
159 | FLI1 | 4729 | 18402 | -6.008 | 0.0116 | No |