Dataset | Set_04_transDMpreB_versus_WTpreB.phenotype_transDMpreB_versus_WTpreB.cls #transDMpreB_versus_WTpreB |
Phenotype | phenotype_transDMpreB_versus_WTpreB.cls#transDMpreB_versus_WTpreB |
Upregulated in class | transDMpreB |
GeneSet | V$E2F1DP1_01 |
Enrichment Score (ES) | 0.56029904 |
Normalized Enrichment Score (NES) | 1.4320053 |
Nominal p-value | 0.003816794 |
FDR q-value | 0.5627297 |
FWER p-Value | 0.986 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | EIF4A1 | 8889 23719 | 38 | 8.864 | 0.0365 | Yes | ||
2 | SNRPD1 | 23622 | 192 | 6.236 | 0.0554 | Yes | ||
3 | CDCA7 | 12437 | 210 | 6.035 | 0.0808 | Yes | ||
4 | UNG | 10257 16744 | 232 | 5.883 | 0.1053 | Yes | ||
5 | FANCD2 | 17326 464 | 240 | 5.822 | 0.1302 | Yes | ||
6 | FKBP5 | 23051 | 329 | 5.237 | 0.1483 | Yes | ||
7 | GSPT1 | 9046 | 357 | 5.076 | 0.1689 | Yes | ||
8 | MCM3 | 13991 | 372 | 4.986 | 0.1899 | Yes | ||
9 | RQCD1 | 12205 | 397 | 4.875 | 0.2098 | Yes | ||
10 | CDC25A | 8721 | 411 | 4.833 | 0.2302 | Yes | ||
11 | MCM2 | 17074 | 445 | 4.703 | 0.2489 | Yes | ||
12 | MSH2 | 23138 | 583 | 4.074 | 0.2592 | Yes | ||
13 | ACBD6 | 14089 | 621 | 3.968 | 0.2745 | Yes | ||
14 | PHF5A | 22194 | 627 | 3.958 | 0.2914 | Yes | ||
15 | DNMT1 | 19217 | 641 | 3.927 | 0.3078 | Yes | ||
16 | HMGA1 | 23323 | 710 | 3.664 | 0.3201 | Yes | ||
17 | NOLC1 | 7704 | 728 | 3.609 | 0.3349 | Yes | ||
18 | POLD3 | 17742 | 746 | 3.578 | 0.3496 | Yes | ||
19 | GMNN | 21513 | 749 | 3.568 | 0.3650 | Yes | ||
20 | PRPS1 | 24233 | 811 | 3.405 | 0.3765 | Yes | ||
21 | MAP3K7 | 16255 | 878 | 3.198 | 0.3869 | Yes | ||
22 | HIRA | 4852 9090 | 979 | 2.952 | 0.3943 | Yes | ||
23 | ACO2 | 8527 | 984 | 2.941 | 0.4069 | Yes | ||
24 | MRPL40 | 22641 | 993 | 2.919 | 0.4192 | Yes | ||
25 | NUP62 | 9497 | 1020 | 2.854 | 0.4302 | Yes | ||
26 | SMAD6 | 19083 | 1090 | 2.735 | 0.4384 | Yes | ||
27 | PCNA | 9535 | 1127 | 2.676 | 0.4481 | Yes | ||
28 | NCL | 5153 13899 | 1212 | 2.514 | 0.4545 | Yes | ||
29 | NASP | 2383 2387 6955 | 1225 | 2.494 | 0.4647 | Yes | ||
30 | ILF3 | 3110 3030 9176 | 1240 | 2.476 | 0.4747 | Yes | ||
31 | EED | 17759 | 1249 | 2.461 | 0.4850 | Yes | ||
32 | AP1S1 | 3500 3453 16335 | 1306 | 2.379 | 0.4923 | Yes | ||
33 | SUMO1 | 5826 3943 10247 | 1350 | 2.328 | 0.5001 | Yes | ||
34 | SUV39H1 | 24194 | 1410 | 2.217 | 0.5066 | Yes | ||
35 | RRM2 | 5401 5400 | 1481 | 2.084 | 0.5119 | Yes | ||
36 | PRPS2 | 24003 | 1523 | 2.022 | 0.5185 | Yes | ||
37 | MCM7 | 9372 3568 | 1539 | 1.995 | 0.5263 | Yes | ||
38 | BRPF1 | 17332 | 1574 | 1.942 | 0.5330 | Yes | ||
39 | SFRS1 | 8492 | 1857 | 1.596 | 0.5246 | Yes | ||
40 | CLSPN | 16079 11256 6530 | 1890 | 1.549 | 0.5296 | Yes | ||
41 | SYNCRIP | 3078 3035 3107 | 1899 | 1.539 | 0.5359 | Yes | ||
42 | STMN1 | 9261 | 1957 | 1.452 | 0.5391 | Yes | ||
43 | E2F1 | 14384 | 1966 | 1.442 | 0.5450 | Yes | ||
44 | E2F7 | 19884 | 2086 | 1.299 | 0.5442 | Yes | ||
45 | ZCCHC8 | 3570 7696 | 2131 | 1.233 | 0.5472 | Yes | ||
46 | PHC1 | 17013 | 2136 | 1.230 | 0.5523 | Yes | ||
47 | USP37 | 13923 | 2155 | 1.208 | 0.5566 | Yes | ||
48 | BRMS1L | 21268 | 2183 | 1.179 | 0.5603 | Yes | ||
49 | E2F3 | 21500 8874 | 2288 | 1.048 | 0.5592 | No | ||
50 | HTF9C | 4886 1678 | 2513 | 0.889 | 0.5510 | No | ||
51 | FHOD1 | 18772 | 2527 | 0.882 | 0.5541 | No | ||
52 | FANCC | 4712 | 2538 | 0.873 | 0.5574 | No | ||
53 | POLR2A | 5394 | 2663 | 0.775 | 0.5540 | No | ||
54 | TRIM39 | 22994 | 2667 | 0.772 | 0.5572 | No | ||
55 | SFRS7 | 22889 | 2779 | 0.674 | 0.5542 | No | ||
56 | NR6A1 | 14596 | 2796 | 0.662 | 0.5562 | No | ||
57 | PTMA | 9657 | 2914 | 0.576 | 0.5523 | No | ||
58 | CDC5L | 7746 7745 7744 | 2952 | 0.557 | 0.5528 | No | ||
59 | USP52 | 3397 19841 | 3056 | 0.489 | 0.5493 | No | ||
60 | PRKDC | 9617 22847 | 3126 | 0.448 | 0.5475 | No | ||
61 | ASXL2 | 7957 | 3193 | 0.413 | 0.5458 | No | ||
62 | MAPT | 9420 1347 | 3311 | 0.367 | 0.5410 | No | ||
63 | GATA1 | 24196 | 3313 | 0.366 | 0.5426 | No | ||
64 | MAZ | 1327 17623 | 3902 | 0.209 | 0.5116 | No | ||
65 | SEMA6A | 23439 9802 | 3948 | 0.201 | 0.5101 | No | ||
66 | CDC6 | 6221 6220 | 4074 | 0.180 | 0.5041 | No | ||
67 | PAQR4 | 23105 | 4278 | 0.155 | 0.4938 | No | ||
68 | FBXO5 | 19830 | 4774 | 0.111 | 0.4674 | No | ||
69 | KCNA6 | 664 16990 665 4938 | 5006 | 0.096 | 0.4553 | No | ||
70 | PHF15 | 20467 8050 | 5278 | 0.082 | 0.4410 | No | ||
71 | FANCG | 15904 | 5732 | 0.063 | 0.4168 | No | ||
72 | RANBP1 | 9692 5357 | 5788 | 0.062 | 0.4140 | No | ||
73 | YBX2 | 20818 | 5844 | 0.060 | 0.4113 | No | ||
74 | ARID4A | 2080 6215 | 5853 | 0.060 | 0.4112 | No | ||
75 | GLRA3 | 18617 | 5865 | 0.060 | 0.4108 | No | ||
76 | HNRPUL1 | 6118 17923 1608 10577 1345 | 5894 | 0.059 | 0.4096 | No | ||
77 | ATAD2 | 2268 2256 | 6038 | 0.055 | 0.4020 | No | ||
78 | POU4F1 | 21727 | 6059 | 0.054 | 0.4012 | No | ||
79 | IPO7 | 6130 | 6750 | 0.039 | 0.3640 | No | ||
80 | STAG1 | 5520 9905 2987 | 7002 | 0.035 | 0.3506 | No | ||
81 | KCNS2 | 4949 2232 | 7006 | 0.035 | 0.3505 | No | ||
82 | GRIA4 | 19249 | 7078 | 0.033 | 0.3468 | No | ||
83 | SLCO3A1 | 17796 4237 8430 | 7122 | 0.033 | 0.3447 | No | ||
84 | MYH10 | 8077 | 7677 | 0.024 | 0.3148 | No | ||
85 | STK35 | 14851 | 7678 | 0.024 | 0.3149 | No | ||
86 | POLE2 | 21053 | 7814 | 0.022 | 0.3076 | No | ||
87 | NELL2 | 12006 7020 22151 | 7996 | 0.020 | 0.2979 | No | ||
88 | ZBTB4 | 13267 | 8019 | 0.019 | 0.2968 | No | ||
89 | SFRS10 | 9818 1722 5441 | 8049 | 0.019 | 0.2953 | No | ||
90 | PCSK1 | 21600 | 8125 | 0.018 | 0.2913 | No | ||
91 | HNRPA2B1 | 1187 7001 7000 1040 | 8228 | 0.016 | 0.2859 | No | ||
92 | GABRB3 | 4747 | 8278 | 0.016 | 0.2833 | No | ||
93 | HOXC10 | 22342 | 8430 | 0.014 | 0.2752 | No | ||
94 | PODN | 15811 | 8681 | 0.010 | 0.2617 | No | ||
95 | TYRO3 | 5811 | 8858 | 0.008 | 0.2522 | No | ||
96 | ADAMTS2 | 5706 20899 1356 | 8974 | 0.007 | 0.2460 | No | ||
97 | HNRPD | 8645 | 9217 | 0.004 | 0.2329 | No | ||
98 | DNAJC9 | 21912 | 9225 | 0.004 | 0.2325 | No | ||
99 | FMO4 | 13786 | 9538 | -0.001 | 0.2156 | No | ||
100 | NRK | 6559 | 9714 | -0.003 | 0.2062 | No | ||
101 | PAX6 | 5223 | 10181 | -0.009 | 0.1810 | No | ||
102 | SLITRK4 | 24144 | 10301 | -0.010 | 0.1746 | No | ||
103 | PRPF4B | 3208 5295 | 10398 | -0.012 | 0.1694 | No | ||
104 | RPS6KA5 | 2076 21005 | 10489 | -0.013 | 0.1646 | No | ||
105 | TOPBP1 | 10659 | 10535 | -0.013 | 0.1622 | No | ||
106 | EPHB1 | 19024 | 10967 | -0.019 | 0.1390 | No | ||
107 | SP3 | 5483 | 11020 | -0.020 | 0.1362 | No | ||
108 | RET | 17028 | 11047 | -0.021 | 0.1349 | No | ||
109 | CBX3 | 8705 4484 | 11399 | -0.026 | 0.1160 | No | ||
110 | CASP8AP2 | 16253 | 11427 | -0.026 | 0.1147 | No | ||
111 | HCN3 | 4843 1763 | 11507 | -0.027 | 0.1105 | No | ||
112 | PLAGL1 | 10372 3414 | 11764 | -0.032 | 0.0968 | No | ||
113 | EZH2 | 1092 17163 | 12641 | -0.051 | 0.0496 | No | ||
114 | TBX6 | 1993 18075 | 12826 | -0.056 | 0.0398 | No | ||
115 | ARHGAP6 | 24207 | 12930 | -0.059 | 0.0345 | No | ||
116 | HS6ST3 | 21933 | 13040 | -0.063 | 0.0289 | No | ||
117 | PEG3 | 5240 | 13230 | -0.069 | 0.0190 | No | ||
118 | SYNGR4 | 17825 | 13769 | -0.095 | -0.0098 | No | ||
119 | HNRPR | 13196 7909 2500 | 13785 | -0.096 | -0.0102 | No | ||
120 | GPRC5B | 17662 | 14187 | -0.126 | -0.0313 | No | ||
121 | RBL1 | 14373 | 14231 | -0.130 | -0.0331 | No | ||
122 | TLE3 | 5767 19416 | 14526 | -0.159 | -0.0483 | No | ||
123 | MCM8 | 14834 | 14591 | -0.168 | -0.0511 | No | ||
124 | DMD | 24295 2647 | 14880 | -0.212 | -0.0657 | No | ||
125 | MYC | 22465 9435 | 14983 | -0.233 | -0.0702 | No | ||
126 | MAPK6 | 19062 | 15221 | -0.286 | -0.0818 | No | ||
127 | EFNA5 | 4655 8884 | 15319 | -0.314 | -0.0857 | No | ||
128 | CCNT1 | 22140 11607 | 15392 | -0.339 | -0.0881 | No | ||
129 | MSH5 | 23010 1599 | 15631 | -0.435 | -0.0991 | No | ||
130 | AP4M1 | 3499 16656 | 15643 | -0.438 | -0.0978 | No | ||
131 | RPS20 | 7438 | 15692 | -0.460 | -0.0984 | No | ||
132 | ATF5 | 17843 | 15697 | -0.462 | -0.0966 | No | ||
133 | MCM6 | 4000 13845 4119 | 15750 | -0.489 | -0.0973 | No | ||
134 | CORT | 15669 2539 | 15920 | -0.593 | -0.1039 | No | ||
135 | H2AFZ | 6957 | 16123 | -0.772 | -0.1115 | No | ||
136 | TMPO | 5778 | 16191 | -0.856 | -0.1114 | No | ||
137 | UGCGL1 | 6721 | 16210 | -0.870 | -0.1086 | No | ||
138 | MCM4 | 22655 1708 | 16371 | -1.005 | -0.1128 | No | ||
139 | HIST1H2AH | 11414 | 16813 | -1.529 | -0.1301 | No | ||
140 | ING3 | 17514 1019 | 16839 | -1.576 | -0.1246 | No | ||
141 | AK2 | 8563 2479 16073 | 16931 | -1.712 | -0.1220 | No | ||
142 | POLD1 | 17847 | 17042 | -1.851 | -0.1199 | No | ||
143 | SLC9A7 | 24177 | 17097 | -1.949 | -0.1144 | No | ||
144 | ALDH6A1 | 21025 | 17108 | -1.975 | -0.1063 | No | ||
145 | PIM1 | 23308 | 17289 | -2.292 | -0.1061 | No | ||
146 | POLE4 | 12441 | 17502 | -2.639 | -0.1061 | No | ||
147 | HIST1H2BK | 11423 | 17527 | -2.689 | -0.0956 | No | ||
148 | HIST1H4A | 11590 | 17734 | -3.148 | -0.0931 | No | ||
149 | H2AFV | 1273 20531 | 17949 | -3.802 | -0.0881 | No | ||
150 | SOAT1 | 13797 | 18022 | -4.030 | -0.0745 | No | ||
151 | DCK | 16808 | 18181 | -4.761 | -0.0623 | No | ||
152 | PPM1D | 20721 | 18221 | -4.979 | -0.0427 | No | ||
153 | MXD3 | 21455 | 18327 | -5.489 | -0.0245 | No | ||
154 | IL4I1 | 8971 | 18601 | -9.209 | 0.0008 | No |