Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | wtNotch |
GeneSet | CELL_CYCLE_PROCESS |
Enrichment Score (ES) | 0.54264 |
Normalized Enrichment Score (NES) | 1.6852595 |
Nominal p-value | 0.0031746032 |
FDR q-value | 0.28846008 |
FWER p-Value | 0.695 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | NCAPH | 6220435 | 56 | 3.183 | 0.0252 | Yes | ||
2 | AKAP8 | 4210026 | 57 | 3.171 | 0.0534 | Yes | ||
3 | KPNA2 | 3450114 | 125 | 2.781 | 0.0744 | Yes | ||
4 | BUB1B | 1450288 | 261 | 2.413 | 0.0886 | Yes | ||
5 | POLE | 6020538 | 265 | 2.398 | 0.1097 | Yes | ||
6 | ANAPC4 | 4540338 | 272 | 2.384 | 0.1305 | Yes | ||
7 | MAD2L1 | 4480725 | 273 | 2.379 | 0.1516 | Yes | ||
8 | TPX2 | 6420324 | 306 | 2.306 | 0.1704 | Yes | ||
9 | RB1 | 5900338 | 390 | 2.152 | 0.1850 | Yes | ||
10 | POLS | 5890438 | 424 | 2.095 | 0.2018 | Yes | ||
11 | CUL3 | 1850520 | 446 | 2.066 | 0.2190 | Yes | ||
12 | SKP2 | 360711 380093 4810368 | 483 | 2.012 | 0.2349 | Yes | ||
13 | ANAPC5 | 730164 7100685 | 597 | 1.862 | 0.2453 | Yes | ||
14 | NUSAP1 | 940048 3120435 | 714 | 1.733 | 0.2544 | Yes | ||
15 | CDC7 | 4060546 4850041 | 725 | 1.718 | 0.2692 | Yes | ||
16 | CUL1 | 1990632 | 772 | 1.677 | 0.2816 | Yes | ||
17 | PTPRC | 130402 5290148 | 788 | 1.663 | 0.2955 | Yes | ||
18 | PPP6C | 2450670 | 840 | 1.613 | 0.3071 | Yes | ||
19 | NDC80 | 4120465 | 867 | 1.583 | 0.3197 | Yes | ||
20 | CETN3 | 3170402 | 948 | 1.485 | 0.3286 | Yes | ||
21 | ZWINT | 6940670 | 954 | 1.481 | 0.3414 | Yes | ||
22 | PRC1 | 870092 5890204 | 962 | 1.472 | 0.3541 | Yes | ||
23 | KIF23 | 5570112 | 1019 | 1.409 | 0.3636 | Yes | ||
24 | GSPT1 | 5420050 | 1023 | 1.408 | 0.3759 | Yes | ||
25 | CDKN1C | 6520577 | 1081 | 1.353 | 0.3849 | Yes | ||
26 | MPHOSPH6 | 5570164 | 1179 | 1.259 | 0.3908 | Yes | ||
27 | LIG3 | 2940300 | 1266 | 1.187 | 0.3967 | Yes | ||
28 | KHDRBS1 | 1240403 6040040 | 1297 | 1.152 | 0.4053 | Yes | ||
29 | HSPA2 | 6420592 | 1304 | 1.149 | 0.4151 | Yes | ||
30 | AURKA | 780537 | 1317 | 1.140 | 0.4246 | Yes | ||
31 | SMC1A | 3060600 5700148 5890113 6370154 | 1333 | 1.130 | 0.4338 | Yes | ||
32 | ZW10 | 2900735 3520687 | 1362 | 1.103 | 0.4421 | Yes | ||
33 | CDKN2A | 4670215 4760047 | 1380 | 1.090 | 0.4509 | Yes | ||
34 | TIPIN | 1570301 2480113 | 1432 | 1.048 | 0.4574 | Yes | ||
35 | PCBP4 | 6350722 | 1563 | 0.991 | 0.4591 | Yes | ||
36 | CD28 | 1400739 4210093 | 1578 | 0.983 | 0.4671 | Yes | ||
37 | CDC16 | 1940706 | 1589 | 0.980 | 0.4753 | Yes | ||
38 | KNTC1 | 430079 | 1652 | 0.940 | 0.4803 | Yes | ||
39 | RAD51L3 | 2230609 2810286 3190008 3390053 4230168 | 1703 | 0.906 | 0.4856 | Yes | ||
40 | RAD21 | 1990278 | 1781 | 0.856 | 0.4890 | Yes | ||
41 | BIRC5 | 110408 580014 1770632 | 1894 | 0.790 | 0.4900 | Yes | ||
42 | ABL1 | 1050593 2030050 4010114 | 1898 | 0.789 | 0.4968 | Yes | ||
43 | CDK2AP1 | 2340156 | 1928 | 0.770 | 0.5021 | Yes | ||
44 | DLG7 | 3120041 | 1942 | 0.763 | 0.5082 | Yes | ||
45 | MRE11A | 3850601 4670332 | 1958 | 0.748 | 0.5140 | Yes | ||
46 | NDE1 | 1580242 3830097 | 2027 | 0.703 | 0.5165 | Yes | ||
47 | CDC6 | 4570296 5360600 | 2159 | 0.641 | 0.5151 | Yes | ||
48 | STMN1 | 1990717 | 2167 | 0.636 | 0.5204 | Yes | ||
49 | CCNA2 | 5290075 | 2176 | 0.634 | 0.5256 | Yes | ||
50 | MYH10 | 2640673 | 2217 | 0.614 | 0.5289 | Yes | ||
51 | RAD50 | 4050184 6770746 | 2314 | 0.577 | 0.5288 | Yes | ||
52 | SUGT1 | 1690670 | 2430 | 0.532 | 0.5273 | Yes | ||
53 | CIT | 2370601 | 2435 | 0.528 | 0.5318 | Yes | ||
54 | SMC4 | 5910240 | 2448 | 0.524 | 0.5358 | Yes | ||
55 | EGF | 5220154 | 2474 | 0.515 | 0.5390 | Yes | ||
56 | CUL4A | 1170088 2320008 2470278 | 2506 | 0.504 | 0.5418 | Yes | ||
57 | SSSCA1 | 1240402 780309 | 2608 | 0.469 | 0.5405 | Yes | ||
58 | XRCC2 | 4920706 | 2644 | 0.458 | 0.5426 | Yes | ||
59 | PPP5C | 3130047 | 2795 | 0.409 | 0.5381 | No | ||
60 | NOLC1 | 2350195 | 2875 | 0.381 | 0.5372 | No | ||
61 | GFI1 | 730180 | 2907 | 0.371 | 0.5389 | No | ||
62 | KIF22 | 1190368 | 3067 | 0.321 | 0.5331 | No | ||
63 | LATS2 | 4480593 6020494 | 3166 | 0.294 | 0.5304 | No | ||
64 | RAD17 | 5220739 | 3194 | 0.288 | 0.5315 | No | ||
65 | CDK2 | 130484 2260301 4010088 5050110 | 3216 | 0.284 | 0.5329 | No | ||
66 | TUBG1 | 3140204 | 3242 | 0.280 | 0.5340 | No | ||
67 | BRCA2 | 4280372 | 3259 | 0.274 | 0.5356 | No | ||
68 | ACVR1B | 3610446 5570195 | 3271 | 0.272 | 0.5374 | No | ||
69 | RAD51 | 6110450 6980280 | 3499 | 0.225 | 0.5271 | No | ||
70 | RAD51L1 | 4010112 5860435 | 3548 | 0.213 | 0.5264 | No | ||
71 | GFI1B | 4570131 | 3607 | 0.204 | 0.5250 | No | ||
72 | PIN1 | 2970408 | 3758 | 0.180 | 0.5185 | No | ||
73 | TGFA | 1570332 | 3820 | 0.172 | 0.5167 | No | ||
74 | SMC3 | 870546 1400411 5700039 6450577 | 3910 | 0.158 | 0.5133 | No | ||
75 | NPM2 | 6040139 | 4003 | 0.148 | 0.5096 | No | ||
76 | CDKN1B | 3800025 6450044 | 4044 | 0.142 | 0.5087 | No | ||
77 | DDX11 | 6590671 | 4135 | 0.133 | 0.5050 | No | ||
78 | CDC25C | 2570673 4760161 6520707 | 4241 | 0.124 | 0.5005 | No | ||
79 | USH1C | 1570372 4230364 | 4394 | 0.110 | 0.4932 | No | ||
80 | PML | 50093 2190435 2450402 3840082 | 4633 | 0.093 | 0.4811 | No | ||
81 | FBXO5 | 2630551 | 4653 | 0.092 | 0.4809 | No | ||
82 | TUBE1 | 2360079 6520685 | 4664 | 0.091 | 0.4812 | No | ||
83 | ATM | 3610110 4050524 | 4686 | 0.090 | 0.4808 | No | ||
84 | DCTN3 | 6840131 | 4767 | 0.085 | 0.4773 | No | ||
85 | SYCP1 | 2570010 | 4855 | 0.080 | 0.4733 | No | ||
86 | PIM2 | 840136 5720692 7100577 | 4931 | 0.076 | 0.4699 | No | ||
87 | CDC23 | 3190593 | 5157 | 0.066 | 0.4583 | No | ||
88 | KIF15 | 610731 4070731 6520014 | 5200 | 0.064 | 0.4566 | No | ||
89 | NBN | 730538 2470619 4780594 | 5294 | 0.060 | 0.4521 | No | ||
90 | CHEK1 | 50167 1940300 | 5327 | 0.059 | 0.4508 | No | ||
91 | EPGN | 6980450 | 5333 | 0.059 | 0.4511 | No | ||
92 | RAD52 | 110093 | 5862 | 0.041 | 0.4229 | No | ||
93 | TTK | 3800129 | 6467 | 0.026 | 0.3904 | No | ||
94 | SPO11 | 540288 4780239 | 6593 | 0.023 | 0.3838 | No | ||
95 | CENPF | 5050088 | 6665 | 0.022 | 0.3801 | No | ||
96 | PAM | 5290528 | 6751 | 0.020 | 0.3757 | No | ||
97 | ANAPC10 | 870086 1170037 2260129 | 6773 | 0.019 | 0.3747 | No | ||
98 | RAN | 2260446 4590647 | 6789 | 0.019 | 0.3741 | No | ||
99 | CDKN1A | 4050088 6400706 | 6815 | 0.019 | 0.3729 | No | ||
100 | KIF2C | 6940082 | 6866 | 0.018 | 0.3704 | No | ||
101 | MDM4 | 4070504 4780008 | 7308 | 0.010 | 0.3466 | No | ||
102 | CCNA1 | 6290113 | 7823 | 0.001 | 0.3187 | No | ||
103 | EREG | 50519 4920129 | 7933 | -0.001 | 0.3128 | No | ||
104 | BUB1 | 5390270 | 8457 | -0.009 | 0.2846 | No | ||
105 | MSH4 | 3940068 | 8994 | -0.018 | 0.2557 | No | ||
106 | POLA1 | 4760541 | 9007 | -0.018 | 0.2552 | No | ||
107 | NPM1 | 4730427 | 9124 | -0.020 | 0.2491 | No | ||
108 | KIF11 | 5390139 | 9371 | -0.025 | 0.2360 | No | ||
109 | TIMELESS | 3710315 | 10080 | -0.038 | 0.1980 | No | ||
110 | CDKN3 | 110520 | 10134 | -0.039 | 0.1954 | No | ||
111 | TTN | 2320161 4670056 6550026 | 10145 | -0.039 | 0.1952 | No | ||
112 | PRMT5 | 2760180 4590072 | 10509 | -0.047 | 0.1760 | No | ||
113 | CETN1 | 6020056 | 10660 | -0.050 | 0.1683 | No | ||
114 | APBB2 | 5130403 | 10683 | -0.051 | 0.1676 | No | ||
115 | KATNA1 | 6290048 | 10704 | -0.051 | 0.1669 | No | ||
116 | NEK2 | 2120520 | 10893 | -0.056 | 0.1572 | No | ||
117 | PAFAH1B1 | 4230333 6420121 6450066 | 11397 | -0.070 | 0.1306 | No | ||
118 | CLIP1 | 2850162 6770397 | 11827 | -0.084 | 0.1081 | No | ||
119 | DMC1 | 450341 | 12054 | -0.092 | 0.0967 | No | ||
120 | CUL5 | 450142 | 12089 | -0.094 | 0.0957 | No | ||
121 | NEK6 | 3360687 | 12419 | -0.109 | 0.0788 | No | ||
122 | RAD1 | 4200551 | 12723 | -0.125 | 0.0635 | No | ||
123 | CENPE | 2850022 | 12747 | -0.126 | 0.0634 | No | ||
124 | TBRG4 | 3610239 6370594 | 12866 | -0.133 | 0.0582 | No | ||
125 | CDCA5 | 5670131 | 13200 | -0.156 | 0.0415 | No | ||
126 | PLK1 | 1780369 2640121 | 13227 | -0.159 | 0.0415 | No | ||
127 | UBE2C | 6130017 | 13412 | -0.173 | 0.0331 | No | ||
128 | ANLN | 1780113 2470537 6840047 | 13567 | -0.187 | 0.0264 | No | ||
129 | CDKN2B | 6020040 | 13572 | -0.187 | 0.0278 | No | ||
130 | ANAPC11 | 1780601 | 13588 | -0.189 | 0.0287 | No | ||
131 | DUSP13 | 6400152 | 13809 | -0.211 | 0.0187 | No | ||
132 | ACVR1 | 6840671 | 13964 | -0.228 | 0.0123 | No | ||
133 | RCC1 | 2480358 | 14128 | -0.246 | 0.0057 | No | ||
134 | TPD52L1 | 4590711 5570575 | 14225 | -0.260 | 0.0028 | No | ||
135 | RAD54L | 2970041 | 14358 | -0.276 | -0.0019 | No | ||
136 | CUL2 | 4200278 | 14495 | -0.298 | -0.0066 | No | ||
137 | DCTN2 | 540471 3780717 | 14688 | -0.333 | -0.0141 | No | ||
138 | CDKN2D | 6040035 | 14900 | -0.370 | -0.0222 | No | ||
139 | CENTD2 | 60408 2510156 6100494 | 15112 | -0.415 | -0.0300 | No | ||
140 | APBB1 | 2690338 | 15141 | -0.422 | -0.0277 | No | ||
141 | RACGAP1 | 3990162 6620736 | 15208 | -0.437 | -0.0274 | No | ||
142 | CDK6 | 4920253 | 15335 | -0.469 | -0.0301 | No | ||
143 | TOP3A | 7000435 | 15350 | -0.476 | -0.0266 | No | ||
144 | E2F1 | 5360093 | 15379 | -0.483 | -0.0239 | No | ||
145 | BOLL | 6100743 | 15568 | -0.545 | -0.0292 | No | ||
146 | NUMA1 | 6520576 | 15578 | -0.548 | -0.0248 | No | ||
147 | TGFB1 | 1940162 | 15749 | -0.610 | -0.0286 | No | ||
148 | STAG3 | 3830112 | 15933 | -0.682 | -0.0325 | No | ||
149 | CDKN2C | 5050750 5130148 | 15989 | -0.707 | -0.0292 | No | ||
150 | TARDBP | 870390 2350093 | 16452 | -0.917 | -0.0461 | No | ||
151 | POLD1 | 4830026 | 16821 | -1.079 | -0.0564 | No | ||
152 | MAP3K11 | 7000039 | 17023 | -1.210 | -0.0566 | No | ||
153 | CHFR | 3390050 6450300 6450736 | 17127 | -1.272 | -0.0509 | No | ||
154 | CDC25B | 6940102 | 17519 | -1.538 | -0.0584 | No | ||
155 | CHMP1A | 5550441 | 17651 | -1.647 | -0.0509 | No | ||
156 | MSH5 | 1340019 4730333 | 17655 | -1.651 | -0.0364 | No | ||
157 | MAD2L2 | 1240358 | 17788 | -1.784 | -0.0277 | No | ||
158 | CDK4 | 540075 4540600 | 18101 | -2.120 | -0.0258 | No | ||
159 | BCAT1 | 3290128 4050408 | 18470 | -2.890 | -0.0200 | No | ||
160 | CDK10 | 60164 1190717 3130128 3990044 | 18523 | -3.142 | 0.0050 | No |