Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$SRF_Q5_01 |
Enrichment Score (ES) | -0.4572772 |
Normalized Enrichment Score (NES) | -1.3287858 |
Nominal p-value | 0.02425107 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | H3F3A | 2900086 | 702 | 1.745 | -0.0191 | No | ||
2 | RBBP7 | 430113 450450 2370309 | 748 | 1.701 | -0.0032 | No | ||
3 | HOXB4 | 540131 | 766 | 1.681 | 0.0141 | No | ||
4 | ATF4 | 730441 1740195 | 852 | 1.594 | 0.0268 | No | ||
5 | KCNH2 | 1170451 | 1144 | 1.287 | 0.0250 | No | ||
6 | MAPK14 | 5290731 | 1301 | 1.150 | 0.0290 | No | ||
7 | TPM3 | 670600 3170296 5670167 6650471 | 1548 | 0.998 | 0.0265 | No | ||
8 | CFL1 | 2340735 | 1650 | 0.941 | 0.0312 | No | ||
9 | EML4 | 5700373 | 1651 | 0.941 | 0.0414 | No | ||
10 | LDB1 | 5270601 | 1782 | 0.855 | 0.0436 | No | ||
11 | SCOC | 610048 2230053 | 1945 | 0.761 | 0.0431 | No | ||
12 | MBNL1 | 2640762 7100048 | 2031 | 0.700 | 0.0461 | No | ||
13 | DGKG | 1770025 | 2154 | 0.643 | 0.0464 | No | ||
14 | SLC25A4 | 2360519 | 2158 | 0.642 | 0.0532 | No | ||
15 | ERBB2IP | 580253 1090672 | 2205 | 0.621 | 0.0575 | No | ||
16 | FOXP1 | 6510433 | 2240 | 0.605 | 0.0622 | No | ||
17 | CSDA | 2470092 3060053 4780056 | 2332 | 0.572 | 0.0634 | No | ||
18 | SVIL | 2450347 4050735 4070576 4120706 5390161 5860142 6520278 7100397 | 2335 | 0.569 | 0.0695 | No | ||
19 | KRTCAP2 | 5220040 | 2372 | 0.553 | 0.0735 | No | ||
20 | PPP1R12A | 4070066 4590162 | 2404 | 0.543 | 0.0777 | No | ||
21 | SLC16A6 | 1690156 | 2471 | 0.516 | 0.0798 | No | ||
22 | CHD2 | 4070039 | 2546 | 0.490 | 0.0811 | No | ||
23 | LCP1 | 4280397 | 2587 | 0.475 | 0.0840 | No | ||
24 | TIMP3 | 1450504 1980270 | 2689 | 0.443 | 0.0834 | No | ||
25 | VCL | 4120487 | 2812 | 0.405 | 0.0811 | No | ||
26 | PHF12 | 870400 3130687 | 3125 | 0.306 | 0.0675 | No | ||
27 | CORO1C | 4570397 | 3248 | 0.278 | 0.0639 | No | ||
28 | GADD45G | 2510142 | 3423 | 0.240 | 0.0571 | No | ||
29 | PICALM | 1940280 | 3429 | 0.238 | 0.0594 | No | ||
30 | MYL7 | 2480541 | 3597 | 0.205 | 0.0526 | No | ||
31 | ASXL2 | 130670 | 3601 | 0.204 | 0.0546 | No | ||
32 | MAP2K6 | 1230056 2940204 | 4023 | 0.145 | 0.0334 | No | ||
33 | CDKN1B | 3800025 6450044 | 4044 | 0.142 | 0.0338 | No | ||
34 | TRIM3 | 5570156 | 4162 | 0.130 | 0.0289 | No | ||
35 | MID1 | 4070114 4760458 | 4239 | 0.124 | 0.0261 | No | ||
36 | RERE | 3940279 | 4324 | 0.117 | 0.0228 | No | ||
37 | FGF17 | 3130022 | 4451 | 0.106 | 0.0172 | No | ||
38 | OTX1 | 2510215 | 4838 | 0.081 | -0.0029 | No | ||
39 | EFHD1 | 4070358 | 5167 | 0.065 | -0.0200 | No | ||
40 | EGR2 | 3800403 | 5178 | 0.065 | -0.0198 | No | ||
41 | TNMD | 3060520 | 5313 | 0.060 | -0.0264 | No | ||
42 | SDPR | 3360292 | 5440 | 0.055 | -0.0327 | No | ||
43 | GPR20 | 6620601 | 5498 | 0.052 | -0.0352 | No | ||
44 | TRIM46 | 3520609 4590010 | 5532 | 0.051 | -0.0364 | No | ||
45 | FOSB | 1940142 | 5598 | 0.049 | -0.0394 | No | ||
46 | NR2F2 | 3170609 3310577 | 5628 | 0.048 | -0.0405 | No | ||
47 | STARD13 | 540722 | 5779 | 0.043 | -0.0481 | No | ||
48 | THBS1 | 4560494 430288 | 5939 | 0.039 | -0.0563 | No | ||
49 | ITGB6 | 2810068 4570332 | 5945 | 0.038 | -0.0562 | No | ||
50 | ACTR3 | 1400497 | 5984 | 0.037 | -0.0579 | No | ||
51 | PRKAB2 | 6980300 | 5987 | 0.037 | -0.0576 | No | ||
52 | RARB | 430139 1410138 | 6002 | 0.037 | -0.0579 | No | ||
53 | ADAMTSL1 | 2970092 | 6188 | 0.032 | -0.0676 | No | ||
54 | THRAP1 | 2470121 | 6434 | 0.027 | -0.0806 | No | ||
55 | MITF | 380056 | 6574 | 0.024 | -0.0879 | No | ||
56 | NPR3 | 1580239 | 6666 | 0.021 | -0.0926 | No | ||
57 | CRH | 3710301 | 6973 | 0.016 | -0.1090 | No | ||
58 | FGF7 | 5390484 | 7023 | 0.015 | -0.1115 | No | ||
59 | SLC2A4 | 540441 | 7047 | 0.014 | -0.1126 | No | ||
60 | IL17B | 6940711 | 7434 | 0.008 | -0.1334 | No | ||
61 | KCNK3 | 2690372 | 7469 | 0.007 | -0.1352 | No | ||
62 | MYH11 | 7100273 | 7968 | -0.001 | -0.1622 | No | ||
63 | HOXD10 | 6100039 | 8242 | -0.006 | -0.1769 | No | ||
64 | MYL9 | 4210750 7050138 | 8443 | -0.009 | -0.1877 | No | ||
65 | TAGLN | 6660280 | 8531 | -0.010 | -0.1923 | No | ||
66 | DIXDC1 | 6980435 | 8569 | -0.011 | -0.1942 | No | ||
67 | MYO1E | 3140504 | 9122 | -0.020 | -0.2239 | No | ||
68 | NFATC4 | 2470735 | 9158 | -0.021 | -0.2256 | No | ||
69 | ACTA1 | 840538 | 9285 | -0.023 | -0.2321 | No | ||
70 | TRDN | 1580411 | 9421 | -0.025 | -0.2392 | No | ||
71 | ASPA | 3290400 | 9578 | -0.028 | -0.2473 | No | ||
72 | ABCA1 | 6290156 | 9957 | -0.035 | -0.2675 | No | ||
73 | HOXC4 | 1940193 | 10070 | -0.038 | -0.2731 | No | ||
74 | NRXN3 | 1400546 3360471 | 10243 | -0.041 | -0.2820 | No | ||
75 | LPP | 1660541 | 10461 | -0.046 | -0.2933 | No | ||
76 | CXCL5 | 6370333 | 10633 | -0.050 | -0.3020 | No | ||
77 | NKX2-2 | 4150731 | 10656 | -0.050 | -0.3027 | No | ||
78 | KCNA1 | 2030594 | 10718 | -0.052 | -0.3054 | No | ||
79 | CALN1 | 3610722 | 10720 | -0.052 | -0.3049 | No | ||
80 | CNN1 | 510707 | 10741 | -0.052 | -0.3054 | No | ||
81 | NPAS2 | 770670 | 10825 | -0.054 | -0.3093 | No | ||
82 | BNC2 | 4810603 | 10897 | -0.056 | -0.3126 | No | ||
83 | HOXC5 | 1580017 | 10899 | -0.056 | -0.3120 | No | ||
84 | IER2 | 2030008 | 10975 | -0.058 | -0.3155 | No | ||
85 | DSTN | 3140592 | 11071 | -0.061 | -0.3200 | No | ||
86 | TANK | 1090020 2060458 2370400 | 11076 | -0.061 | -0.3195 | No | ||
87 | ABR | 610079 1170609 3610195 5670050 | 11331 | -0.068 | -0.3325 | No | ||
88 | CALD1 | 1770129 1940397 | 11403 | -0.070 | -0.3356 | No | ||
89 | RAI2 | 6770333 | 11484 | -0.072 | -0.3392 | No | ||
90 | MLLT7 | 4480707 | 11595 | -0.076 | -0.3443 | No | ||
91 | PLN | 3940132 | 11784 | -0.083 | -0.3536 | No | ||
92 | RASSF2 | 2480079 5720546 | 11794 | -0.083 | -0.3532 | No | ||
93 | LRRFIP1 | 870259 1050204 2760377 | 11813 | -0.083 | -0.3533 | No | ||
94 | CACNA1B | 1740010 5360593 | 11890 | -0.086 | -0.3565 | No | ||
95 | PODN | 3710068 | 11899 | -0.087 | -0.3560 | No | ||
96 | FLNC | 2360048 5050270 | 11965 | -0.089 | -0.3585 | No | ||
97 | CASQ1 | 6290035 7000707 | 11989 | -0.090 | -0.3588 | No | ||
98 | CHST8 | 1940050 | 12020 | -0.091 | -0.3594 | No | ||
99 | CA3 | 870687 5890390 | 12159 | -0.097 | -0.3659 | No | ||
100 | ATF3 | 1940546 | 12166 | -0.097 | -0.3651 | No | ||
101 | PPARG | 1990168 2680603 6130632 | 12221 | -0.100 | -0.3670 | No | ||
102 | TADA3L | 4210070 5720088 6660333 | 12236 | -0.100 | -0.3667 | No | ||
103 | HOXB5 | 2900538 | 12257 | -0.101 | -0.3667 | No | ||
104 | RIMS1 | 5670022 | 12377 | -0.107 | -0.3719 | No | ||
105 | DLL1 | 1770377 | 12872 | -0.134 | -0.3973 | No | ||
106 | COL23A1 | 2030358 | 12919 | -0.137 | -0.3983 | No | ||
107 | RSU1 | 4850372 | 12932 | -0.138 | -0.3974 | No | ||
108 | SRD5A2 | 6840433 | 12982 | -0.141 | -0.3986 | No | ||
109 | MYLK | 4010600 7000364 | 13035 | -0.144 | -0.3998 | No | ||
110 | ITGB1BP2 | 6200129 | 13080 | -0.148 | -0.4006 | No | ||
111 | STAT5B | 6200026 | 13123 | -0.151 | -0.4013 | No | ||
112 | WNT3 | 2360685 | 13148 | -0.153 | -0.4009 | No | ||
113 | FOXP2 | 3520561 4150372 4760524 | 13179 | -0.155 | -0.4008 | No | ||
114 | PPAP2B | 3190397 4730280 | 13206 | -0.156 | -0.4006 | No | ||
115 | PCDH7 | 450398 4150040 | 13225 | -0.158 | -0.3998 | No | ||
116 | TGFB1I1 | 2060288 6550450 | 13285 | -0.163 | -0.4013 | No | ||
117 | PELI2 | 1940364 | 13377 | -0.170 | -0.4043 | No | ||
118 | CITED2 | 5670114 5130088 | 13832 | -0.213 | -0.4267 | No | ||
119 | ACTG2 | 4780180 | 13871 | -0.217 | -0.4264 | No | ||
120 | PLCB3 | 4670402 | 13955 | -0.227 | -0.4284 | No | ||
121 | FOXE3 | 6900102 | 14018 | -0.234 | -0.4292 | No | ||
122 | SRF | 70139 2320039 | 14038 | -0.235 | -0.4277 | No | ||
123 | LRRTM4 | 5910100 | 14112 | -0.243 | -0.4290 | No | ||
124 | GGN | 1410528 4210082 5290170 | 14150 | -0.249 | -0.4284 | No | ||
125 | MRGPRF | 4780746 | 14252 | -0.264 | -0.4310 | No | ||
126 | NRAS | 6900577 | 14579 | -0.314 | -0.4452 | No | ||
127 | MAP1A | 4920576 | 14671 | -0.329 | -0.4466 | No | ||
128 | FGF8 | 6350504 | 14763 | -0.346 | -0.4478 | No | ||
129 | DVL3 | 360156 5390075 | 14939 | -0.380 | -0.4532 | Yes | ||
130 | ELAVL4 | 50735 3360086 5220167 | 14942 | -0.381 | -0.4491 | Yes | ||
131 | NPPA | 6550328 | 14948 | -0.382 | -0.4453 | Yes | ||
132 | FOS | 1850315 | 14971 | -0.386 | -0.4423 | Yes | ||
133 | NR2F1 | 4120528 360402 | 14973 | -0.386 | -0.4382 | Yes | ||
134 | COL1A1 | 730020 | 15140 | -0.422 | -0.4426 | Yes | ||
135 | TAF5L | 5690152 | 15178 | -0.430 | -0.4399 | Yes | ||
136 | ACTB | 1660736 2030204 2060215 5050047 | 15190 | -0.433 | -0.4358 | Yes | ||
137 | EGR3 | 6940128 | 15198 | -0.434 | -0.4315 | Yes | ||
138 | TPM2 | 520735 3870390 | 15310 | -0.461 | -0.4325 | Yes | ||
139 | JUNB | 4230048 | 15452 | -0.504 | -0.4347 | Yes | ||
140 | SLC4A3 | 360603 4730239 6380347 | 15538 | -0.535 | -0.4335 | Yes | ||
141 | CFL2 | 380239 6200368 | 15581 | -0.551 | -0.4298 | Yes | ||
142 | MYADM | 4230132 | 15696 | -0.592 | -0.4296 | Yes | ||
143 | SGK | 1400131 2480056 | 15969 | -0.698 | -0.4368 | Yes | ||
144 | FGFRL1 | 6370047 | 16069 | -0.745 | -0.4340 | Yes | ||
145 | ANXA6 | 2190014 | 16137 | -0.771 | -0.4293 | Yes | ||
146 | TLE3 | 580040 4730121 | 16160 | -0.780 | -0.4221 | Yes | ||
147 | RHOJ | 6660176 | 16164 | -0.781 | -0.4138 | Yes | ||
148 | RUNDC1 | 2450037 | 16247 | -0.824 | -0.4093 | Yes | ||
149 | EMILIN2 | 70253 | 16321 | -0.857 | -0.4039 | Yes | ||
150 | TAZ | 7100193 | 16586 | -0.983 | -0.4076 | Yes | ||
151 | MRPS21 | 2650008 | 16736 | -1.036 | -0.4044 | Yes | ||
152 | PFN1 | 6130132 | 16915 | -1.144 | -0.4017 | Yes | ||
153 | VASP | 7050500 | 16921 | -1.147 | -0.3895 | Yes | ||
154 | H2AFX | 3520082 | 17204 | -1.332 | -0.3904 | Yes | ||
155 | CKM | 1450524 | 17235 | -1.346 | -0.3774 | Yes | ||
156 | EEF1B2 | 4850400 6130161 | 17418 | -1.472 | -0.3713 | Yes | ||
157 | SERTAD4 | 130593 | 17424 | -1.476 | -0.3556 | Yes | ||
158 | UBE2H | 1980142 2970079 | 17455 | -1.491 | -0.3411 | Yes | ||
159 | CDC25B | 6940102 | 17519 | -1.538 | -0.3278 | Yes | ||
160 | GRK6 | 1500053 | 17717 | -1.715 | -0.3199 | Yes | ||
161 | CSRP1 | 2810403 | 17891 | -1.880 | -0.3089 | Yes | ||
162 | CNN2 | 2230433 5270446 | 17910 | -1.904 | -0.2893 | Yes | ||
163 | EGR1 | 4610347 | 17946 | -1.942 | -0.2701 | Yes | ||
164 | BLOC1S1 | 130341 3940717 | 17951 | -1.953 | -0.2491 | Yes | ||
165 | MUS81 | 6660184 | 17964 | -1.968 | -0.2285 | Yes | ||
166 | PDLIM7 | 4780136 | 17992 | -1.999 | -0.2083 | Yes | ||
167 | MYL6 | 60563 6100152 | 18078 | -2.094 | -0.1902 | Yes | ||
168 | DUSP10 | 2850673 3360064 | 18250 | -2.336 | -0.1741 | Yes | ||
169 | ARF6 | 3520026 | 18261 | -2.362 | -0.1491 | Yes | ||
170 | ASB2 | 4760168 | 18396 | -2.652 | -0.1276 | Yes | ||
171 | ARPC4 | 2900056 | 18417 | -2.722 | -0.0992 | Yes | ||
172 | PADI2 | 2940092 6420136 | 18499 | -2.975 | -0.0713 | Yes | ||
173 | FLNA | 5390193 | 18554 | -3.307 | -0.0384 | Yes | ||
174 | MAPKAPK2 | 2850500 | 18590 | -3.846 | 0.0014 | Yes |