Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$SRF_Q4 |
Enrichment Score (ES) | -0.41942304 |
Normalized Enrichment Score (NES) | -1.2217482 |
Nominal p-value | 0.07244318 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | MCL1 | 1660672 | 6 | 4.296 | 0.0487 | No | ||
2 | RBBP7 | 430113 450450 2370309 | 748 | 1.701 | 0.0279 | No | ||
3 | HOXB4 | 540131 | 766 | 1.681 | 0.0461 | No | ||
4 | AKAP12 | 1450739 | 900 | 1.545 | 0.0566 | No | ||
5 | MAPK14 | 5290731 | 1301 | 1.150 | 0.0480 | No | ||
6 | TPM3 | 670600 3170296 5670167 6650471 | 1548 | 0.998 | 0.0460 | No | ||
7 | MMP14 | 670079 | 1620 | 0.964 | 0.0532 | No | ||
8 | CFL1 | 2340735 | 1650 | 0.941 | 0.0623 | No | ||
9 | EML4 | 5700373 | 1651 | 0.941 | 0.0731 | No | ||
10 | TBL1X | 6400524 | 1777 | 0.858 | 0.0761 | No | ||
11 | SCOC | 610048 2230053 | 1945 | 0.761 | 0.0757 | No | ||
12 | MBNL1 | 2640762 7100048 | 2031 | 0.700 | 0.0791 | No | ||
13 | DGKG | 1770025 | 2154 | 0.643 | 0.0798 | No | ||
14 | SLC25A4 | 2360519 | 2158 | 0.642 | 0.0870 | No | ||
15 | ERBB2IP | 580253 1090672 | 2205 | 0.621 | 0.0915 | No | ||
16 | SORT1 | 1850242 2320632 3870537 | 2234 | 0.608 | 0.0970 | No | ||
17 | FOXP1 | 6510433 | 2240 | 0.605 | 0.1036 | No | ||
18 | CSDA | 2470092 3060053 4780056 | 2332 | 0.572 | 0.1052 | No | ||
19 | SVIL | 2450347 4050735 4070576 4120706 5390161 5860142 6520278 7100397 | 2335 | 0.569 | 0.1116 | No | ||
20 | KRTCAP2 | 5220040 | 2372 | 0.553 | 0.1159 | No | ||
21 | PPP1R12A | 4070066 4590162 | 2404 | 0.543 | 0.1204 | No | ||
22 | CHD2 | 4070039 | 2546 | 0.490 | 0.1184 | No | ||
23 | STAG2 | 4540132 | 2560 | 0.485 | 0.1232 | No | ||
24 | VCL | 4120487 | 2812 | 0.405 | 0.1142 | No | ||
25 | ELF4 | 4850193 | 3035 | 0.330 | 0.1059 | No | ||
26 | PHF12 | 870400 3130687 | 3125 | 0.306 | 0.1046 | No | ||
27 | GADD45G | 2510142 | 3423 | 0.240 | 0.0912 | No | ||
28 | DUSP2 | 2370184 | 3442 | 0.235 | 0.0929 | No | ||
29 | SRP54 | 2970605 | 3489 | 0.227 | 0.0930 | No | ||
30 | MYL7 | 2480541 | 3597 | 0.205 | 0.0896 | No | ||
31 | ARHGEF17 | 2060008 | 3632 | 0.200 | 0.0900 | No | ||
32 | ROCK2 | 1780035 5720025 | 3640 | 0.199 | 0.0919 | No | ||
33 | MAP2K6 | 1230056 2940204 | 4023 | 0.145 | 0.0728 | No | ||
34 | CDKN1B | 3800025 6450044 | 4044 | 0.142 | 0.0734 | No | ||
35 | MID1 | 4070114 4760458 | 4239 | 0.124 | 0.0643 | No | ||
36 | RERE | 3940279 | 4324 | 0.117 | 0.0610 | No | ||
37 | FGF17 | 3130022 | 4451 | 0.106 | 0.0554 | No | ||
38 | EFHD1 | 4070358 | 5167 | 0.065 | 0.0174 | No | ||
39 | EGR2 | 3800403 | 5178 | 0.065 | 0.0176 | No | ||
40 | TNMD | 3060520 | 5313 | 0.060 | 0.0110 | No | ||
41 | SDPR | 3360292 | 5440 | 0.055 | 0.0048 | No | ||
42 | GPR20 | 6620601 | 5498 | 0.052 | 0.0023 | No | ||
43 | TRIM46 | 3520609 4590010 | 5532 | 0.051 | 0.0011 | No | ||
44 | FOSB | 1940142 | 5598 | 0.049 | -0.0018 | No | ||
45 | NR2F2 | 3170609 3310577 | 5628 | 0.048 | -0.0029 | No | ||
46 | ATRX | 2340039 3610132 4210373 | 5863 | 0.041 | -0.0151 | No | ||
47 | THBS1 | 4560494 430288 | 5939 | 0.039 | -0.0187 | No | ||
48 | RARB | 430139 1410138 | 6002 | 0.037 | -0.0217 | No | ||
49 | ADAMTSL1 | 2970092 | 6188 | 0.032 | -0.0313 | No | ||
50 | THRAP1 | 2470121 | 6434 | 0.027 | -0.0443 | No | ||
51 | INSM1 | 3450671 | 6519 | 0.025 | -0.0486 | No | ||
52 | MYL1 | 2450707 | 6531 | 0.025 | -0.0489 | No | ||
53 | EDN1 | 1770047 | 6592 | 0.023 | -0.0519 | No | ||
54 | NPR3 | 1580239 | 6666 | 0.021 | -0.0556 | No | ||
55 | SH3BGR | 840400 | 6784 | 0.019 | -0.0617 | No | ||
56 | CRH | 3710301 | 6973 | 0.016 | -0.0717 | No | ||
57 | NCOA6 | 1780333 6450110 | 7155 | 0.012 | -0.0814 | No | ||
58 | FST | 1110600 | 7183 | 0.012 | -0.0827 | No | ||
59 | NLGN3 | 2650463 | 7375 | 0.009 | -0.0930 | No | ||
60 | IL17B | 6940711 | 7434 | 0.008 | -0.0960 | No | ||
61 | KCNK3 | 2690372 | 7469 | 0.007 | -0.0978 | No | ||
62 | MYH11 | 7100273 | 7968 | -0.001 | -0.1248 | No | ||
63 | HOXD10 | 6100039 | 8242 | -0.006 | -0.1395 | No | ||
64 | RASD2 | 3360010 | 8245 | -0.006 | -0.1396 | No | ||
65 | MSX1 | 2650309 | 8255 | -0.006 | -0.1400 | No | ||
66 | KCNMB1 | 4760139 | 8306 | -0.006 | -0.1426 | No | ||
67 | MYL9 | 4210750 7050138 | 8443 | -0.009 | -0.1499 | No | ||
68 | HOXA5 | 6840026 | 8445 | -0.009 | -0.1498 | No | ||
69 | GAB2 | 1410280 2340520 4280040 | 8529 | -0.010 | -0.1542 | No | ||
70 | TAGLN | 6660280 | 8531 | -0.010 | -0.1542 | No | ||
71 | DIXDC1 | 6980435 | 8569 | -0.011 | -0.1560 | No | ||
72 | MYO1E | 3140504 | 9122 | -0.020 | -0.1857 | No | ||
73 | EGR4 | 3120750 | 9184 | -0.021 | -0.1888 | No | ||
74 | ACTA1 | 840538 | 9285 | -0.023 | -0.1939 | No | ||
75 | ASPA | 3290400 | 9578 | -0.028 | -0.2095 | No | ||
76 | LPP | 1660541 | 10461 | -0.046 | -0.2567 | No | ||
77 | NKX2-2 | 4150731 | 10656 | -0.050 | -0.2667 | No | ||
78 | KCNA1 | 2030594 | 10718 | -0.052 | -0.2694 | No | ||
79 | CALN1 | 3610722 | 10720 | -0.052 | -0.2689 | No | ||
80 | CNN1 | 510707 | 10741 | -0.052 | -0.2694 | No | ||
81 | NR4A1 | 6290161 | 10821 | -0.054 | -0.2730 | No | ||
82 | NPAS2 | 770670 | 10825 | -0.054 | -0.2726 | No | ||
83 | BNC2 | 4810603 | 10897 | -0.056 | -0.2758 | No | ||
84 | HOXC5 | 1580017 | 10899 | -0.056 | -0.2752 | No | ||
85 | IER2 | 2030008 | 10975 | -0.058 | -0.2786 | No | ||
86 | DSTN | 3140592 | 11071 | -0.061 | -0.2830 | No | ||
87 | TANK | 1090020 2060458 2370400 | 11076 | -0.061 | -0.2826 | No | ||
88 | ABR | 610079 1170609 3610195 5670050 | 11331 | -0.068 | -0.2956 | No | ||
89 | CALD1 | 1770129 1940397 | 11403 | -0.070 | -0.2986 | No | ||
90 | TNNC1 | 1990575 | 11645 | -0.077 | -0.3108 | No | ||
91 | RASSF2 | 2480079 5720546 | 11794 | -0.083 | -0.3179 | No | ||
92 | CACNA1B | 1740010 5360593 | 11890 | -0.086 | -0.3220 | No | ||
93 | PODN | 3710068 | 11899 | -0.087 | -0.3215 | No | ||
94 | TMOD1 | 3850100 | 12119 | -0.095 | -0.3323 | No | ||
95 | MYO1B | 770372 | 12152 | -0.097 | -0.3329 | No | ||
96 | PPARG | 1990168 2680603 6130632 | 12221 | -0.100 | -0.3355 | No | ||
97 | TADA3L | 4210070 5720088 6660333 | 12236 | -0.100 | -0.3351 | No | ||
98 | HOXB5 | 2900538 | 12257 | -0.101 | -0.3350 | No | ||
99 | RIMS1 | 5670022 | 12377 | -0.107 | -0.3402 | No | ||
100 | DMD | 1740041 3990332 | 12380 | -0.107 | -0.3391 | No | ||
101 | HOXA3 | 3610632 6020358 | 12646 | -0.121 | -0.3521 | No | ||
102 | DLL1 | 1770377 | 12872 | -0.134 | -0.3628 | No | ||
103 | CTGF | 4540577 | 12887 | -0.135 | -0.3620 | No | ||
104 | COL23A1 | 2030358 | 12919 | -0.137 | -0.3621 | No | ||
105 | RSU1 | 4850372 | 12932 | -0.138 | -0.3612 | No | ||
106 | SRD5A2 | 6840433 | 12982 | -0.141 | -0.3622 | No | ||
107 | MYLK | 4010600 7000364 | 13035 | -0.144 | -0.3634 | No | ||
108 | ITGB1BP2 | 6200129 | 13080 | -0.148 | -0.3641 | No | ||
109 | JPH2 | 940041 5860026 | 13108 | -0.150 | -0.3639 | No | ||
110 | STAT5B | 6200026 | 13123 | -0.151 | -0.3629 | No | ||
111 | FOXP2 | 3520561 4150372 4760524 | 13179 | -0.155 | -0.3641 | No | ||
112 | PPAP2B | 3190397 4730280 | 13206 | -0.156 | -0.3637 | No | ||
113 | TGFB1I1 | 2060288 6550450 | 13285 | -0.163 | -0.3661 | No | ||
114 | CITED2 | 5670114 5130088 | 13832 | -0.213 | -0.3933 | No | ||
115 | ACTG2 | 4780180 | 13871 | -0.217 | -0.3929 | No | ||
116 | ASPH | 360722 1940039 2100066 2340121 2650113 2810064 2970008 3140040 3800750 4210014 4280133 4590035 4760433 6370671 6940338 | 13936 | -0.224 | -0.3938 | No | ||
117 | PLCB3 | 4670402 | 13955 | -0.227 | -0.3922 | No | ||
118 | FOXE3 | 6900102 | 14018 | -0.234 | -0.3929 | No | ||
119 | SRF | 70139 2320039 | 14038 | -0.235 | -0.3912 | No | ||
120 | LRRTM4 | 5910100 | 14112 | -0.243 | -0.3924 | No | ||
121 | MRGPRF | 4780746 | 14252 | -0.264 | -0.3969 | No | ||
122 | CX3CL1 | 3990707 | 14317 | -0.272 | -0.3973 | No | ||
123 | DUSP6 | 5910286 7100070 | 14628 | -0.323 | -0.4104 | No | ||
124 | MAP1A | 4920576 | 14671 | -0.329 | -0.4089 | No | ||
125 | FGF8 | 6350504 | 14763 | -0.346 | -0.4099 | No | ||
126 | DVL3 | 360156 5390075 | 14939 | -0.380 | -0.4151 | Yes | ||
127 | ELAVL4 | 50735 3360086 5220167 | 14942 | -0.381 | -0.4109 | Yes | ||
128 | NPPA | 6550328 | 14948 | -0.382 | -0.4068 | Yes | ||
129 | FOS | 1850315 | 14971 | -0.386 | -0.4036 | Yes | ||
130 | NR2F1 | 4120528 360402 | 14973 | -0.386 | -0.3992 | Yes | ||
131 | TAF5L | 5690152 | 15178 | -0.430 | -0.4054 | Yes | ||
132 | ACTB | 1660736 2030204 2060215 5050047 | 15190 | -0.433 | -0.4010 | Yes | ||
133 | EGR3 | 6940128 | 15198 | -0.434 | -0.3965 | Yes | ||
134 | TPM2 | 520735 3870390 | 15310 | -0.461 | -0.3972 | Yes | ||
135 | JUNB | 4230048 | 15452 | -0.504 | -0.3991 | Yes | ||
136 | SLC4A3 | 360603 4730239 6380347 | 15538 | -0.535 | -0.3976 | Yes | ||
137 | POU3F4 | 870274 | 15540 | -0.535 | -0.3916 | Yes | ||
138 | CFL2 | 380239 6200368 | 15581 | -0.551 | -0.3874 | Yes | ||
139 | IHPK1 | 1340053 | 15889 | -0.661 | -0.3965 | Yes | ||
140 | SGK | 1400131 2480056 | 15969 | -0.698 | -0.3929 | Yes | ||
141 | SERPINH1 | 6130014 | 16061 | -0.742 | -0.3893 | Yes | ||
142 | FGFRL1 | 6370047 | 16069 | -0.745 | -0.3812 | Yes | ||
143 | ANXA6 | 2190014 | 16137 | -0.771 | -0.3761 | Yes | ||
144 | TLE3 | 580040 4730121 | 16160 | -0.780 | -0.3684 | Yes | ||
145 | RHOJ | 6660176 | 16164 | -0.781 | -0.3596 | Yes | ||
146 | RUNDC1 | 2450037 | 16247 | -0.824 | -0.3547 | Yes | ||
147 | EMILIN2 | 70253 | 16321 | -0.857 | -0.3488 | Yes | ||
148 | TAZ | 7100193 | 16586 | -0.983 | -0.3519 | Yes | ||
149 | PFN1 | 6130132 | 16915 | -1.144 | -0.3567 | Yes | ||
150 | VASP | 7050500 | 16921 | -1.147 | -0.3439 | Yes | ||
151 | SLC35A2 | 6770156 | 16929 | -1.153 | -0.3311 | Yes | ||
152 | ESRRA | 6550242 | 17094 | -1.257 | -0.3256 | Yes | ||
153 | H2AFX | 3520082 | 17204 | -1.332 | -0.3164 | Yes | ||
154 | CKM | 1450524 | 17235 | -1.346 | -0.3026 | Yes | ||
155 | EEF1B2 | 4850400 6130161 | 17418 | -1.472 | -0.2957 | Yes | ||
156 | SERTAD4 | 130593 | 17424 | -1.476 | -0.2792 | Yes | ||
157 | GRK6 | 1500053 | 17717 | -1.715 | -0.2754 | Yes | ||
158 | TPM1 | 130673 | 17733 | -1.728 | -0.2565 | Yes | ||
159 | NPM3 | 3610300 | 17751 | -1.742 | -0.2376 | Yes | ||
160 | CSRP1 | 2810403 | 17891 | -1.880 | -0.2237 | Yes | ||
161 | EGR1 | 4610347 | 17946 | -1.942 | -0.2044 | Yes | ||
162 | BLOC1S1 | 130341 3940717 | 17951 | -1.953 | -0.1824 | Yes | ||
163 | MUS81 | 6660184 | 17964 | -1.968 | -0.1606 | Yes | ||
164 | MYL6 | 60563 6100152 | 18078 | -2.094 | -0.1428 | Yes | ||
165 | AGRP | 1990082 | 18178 | -2.207 | -0.1230 | Yes | ||
166 | ARPC4 | 2900056 | 18417 | -2.722 | -0.1049 | Yes | ||
167 | PADI2 | 2940092 6420136 | 18499 | -2.975 | -0.0753 | Yes | ||
168 | FLNA | 5390193 | 18554 | -3.307 | -0.0406 | Yes | ||
169 | MAPKAPK2 | 2850500 | 18590 | -3.846 | 0.0014 | Yes |