Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$SREBP1_Q6 |
Enrichment Score (ES) | -0.41927022 |
Normalized Enrichment Score (NES) | -1.2294226 |
Nominal p-value | 0.07122507 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | KPNB1 | 1690138 | 110 | 2.828 | 0.0213 | No | ||
2 | FCHSD2 | 5720092 | 167 | 2.628 | 0.0436 | No | ||
3 | NMT1 | 5810152 | 280 | 2.373 | 0.0604 | No | ||
4 | PDCD10 | 4760500 | 360 | 2.201 | 0.0773 | No | ||
5 | PIAS1 | 5340301 | 607 | 1.854 | 0.0818 | No | ||
6 | NSF | 4070075 | 1009 | 1.418 | 0.0737 | No | ||
7 | ATP6V1A | 6590242 | 1103 | 1.330 | 0.0815 | No | ||
8 | EMP1 | 4120438 | 1189 | 1.248 | 0.0889 | No | ||
9 | SLIT3 | 7100132 | 1496 | 1.016 | 0.0821 | No | ||
10 | NFIX | 2450152 | 1564 | 0.991 | 0.0880 | No | ||
11 | ZFYVE1 | 60440 | 1606 | 0.973 | 0.0952 | No | ||
12 | MMP14 | 670079 | 1620 | 0.964 | 0.1038 | No | ||
13 | SIPA1L2 | 4850731 | 1664 | 0.930 | 0.1104 | No | ||
14 | ANP32A | 510044 1580095 2680037 | 1686 | 0.919 | 0.1181 | No | ||
15 | EIF4G2 | 3800575 6860184 | 1689 | 0.918 | 0.1269 | No | ||
16 | NFAT5 | 2510411 5890195 6550152 | 1871 | 0.804 | 0.1248 | No | ||
17 | PPP1R10 | 110136 3170725 3610484 | 2113 | 0.666 | 0.1182 | No | ||
18 | MYH10 | 2640673 | 2217 | 0.614 | 0.1185 | No | ||
19 | YWHAQ | 6760524 | 2432 | 0.532 | 0.1120 | No | ||
20 | PHF15 | 6550066 6860673 | 2460 | 0.519 | 0.1155 | No | ||
21 | LASP1 | 1690528 2190341 6420341 | 2487 | 0.511 | 0.1190 | No | ||
22 | DDX6 | 2630025 6770408 | 2488 | 0.510 | 0.1240 | No | ||
23 | STX1A | 3060273 | 2552 | 0.487 | 0.1252 | No | ||
24 | TRERF1 | 6370017 6940138 | 2557 | 0.485 | 0.1297 | No | ||
25 | NTRK3 | 4050687 4070167 4610026 6100484 | 2582 | 0.477 | 0.1330 | No | ||
26 | JUP | 2510671 | 2691 | 0.443 | 0.1314 | No | ||
27 | FXYD1 | 1400239 6560129 | 2700 | 0.440 | 0.1352 | No | ||
28 | DYRK1A | 3190181 | 2750 | 0.423 | 0.1366 | No | ||
29 | EN1 | 5360168 7050025 | 2821 | 0.400 | 0.1367 | No | ||
30 | PACSIN3 | 4540369 4540400 5360037 6940129 | 2921 | 0.367 | 0.1349 | No | ||
31 | PCF11 | 1240180 | 2964 | 0.353 | 0.1360 | No | ||
32 | B4GALT2 | 780037 | 3025 | 0.333 | 0.1359 | No | ||
33 | GPR85 | 5130750 5910020 | 3044 | 0.327 | 0.1381 | No | ||
34 | SLC39A14 | 670300 1400093 1990711 | 3188 | 0.288 | 0.1331 | No | ||
35 | REL | 360707 | 3244 | 0.279 | 0.1328 | No | ||
36 | ZIC4 | 1500082 | 3339 | 0.256 | 0.1302 | No | ||
37 | MAPKAPK3 | 630520 | 3357 | 0.253 | 0.1317 | No | ||
38 | FBS1 | 2570520 | 3463 | 0.231 | 0.1283 | No | ||
39 | BAZ2A | 730184 | 3493 | 0.226 | 0.1289 | No | ||
40 | CLDN5 | 6510717 | 3523 | 0.218 | 0.1294 | No | ||
41 | CLASP1 | 6860279 | 3529 | 0.218 | 0.1312 | No | ||
42 | SOX12 | 1780037 | 3946 | 0.154 | 0.1102 | No | ||
43 | ENO2 | 2320068 | 4140 | 0.133 | 0.1010 | No | ||
44 | RBX1 | 2120010 2340047 | 4144 | 0.132 | 0.1021 | No | ||
45 | DSG4 | 3990605 6400736 | 4206 | 0.127 | 0.1000 | No | ||
46 | POU4F2 | 2120195 2570022 | 4242 | 0.124 | 0.0993 | No | ||
47 | LRP8 | 3610746 5360035 | 4248 | 0.123 | 0.1002 | No | ||
48 | RARG | 6760136 | 4350 | 0.114 | 0.0958 | No | ||
49 | TRAF4 | 3060041 4920528 6980286 | 4421 | 0.107 | 0.0931 | No | ||
50 | SREBF2 | 3390692 | 4567 | 0.098 | 0.0862 | No | ||
51 | KIF1B | 1240494 2370139 4570270 6510102 | 4651 | 0.092 | 0.0825 | No | ||
52 | TEAD2 | 6450079 | 4910 | 0.077 | 0.0693 | No | ||
53 | DHH | 2120433 | 5002 | 0.073 | 0.0651 | No | ||
54 | MEOX2 | 6400288 | 5046 | 0.071 | 0.0634 | No | ||
55 | KCNN3 | 6520600 6420138 | 5078 | 0.069 | 0.0624 | No | ||
56 | CACNA1D | 1740315 4730731 | 5172 | 0.065 | 0.0580 | No | ||
57 | SLC4A10 | 2060670 | 5543 | 0.051 | 0.0384 | No | ||
58 | LIN28 | 6590672 | 5814 | 0.042 | 0.0242 | No | ||
59 | SLC24A1 | 1240463 | 5832 | 0.042 | 0.0237 | No | ||
60 | GUCA2B | 4200014 | 5876 | 0.040 | 0.0217 | No | ||
61 | TCF2 | 870338 5050632 | 5933 | 0.039 | 0.0190 | No | ||
62 | GAP43 | 3130504 | 5951 | 0.038 | 0.0185 | No | ||
63 | GRIA1 | 1340152 3780750 4920440 | 5952 | 0.038 | 0.0189 | No | ||
64 | GFAP | 2060092 | 6081 | 0.035 | 0.0123 | No | ||
65 | GRID2 | 2680242 | 6119 | 0.034 | 0.0106 | No | ||
66 | SLC4A1 | 6290577 | 6305 | 0.030 | 0.0008 | No | ||
67 | DUSP8 | 6650039 | 6341 | 0.029 | -0.0008 | No | ||
68 | EMX2 | 1660092 | 6383 | 0.028 | -0.0028 | No | ||
69 | SERPINI1 | 2940468 | 6397 | 0.028 | -0.0032 | No | ||
70 | SIX4 | 6760022 | 6435 | 0.027 | -0.0049 | No | ||
71 | HYAL1 | 3850341 | 6566 | 0.024 | -0.0118 | No | ||
72 | PLA2G3 | 5130739 | 6681 | 0.021 | -0.0177 | No | ||
73 | GNAO1 | 2510292 6590487 | 6769 | 0.020 | -0.0223 | No | ||
74 | CACNB1 | 2940427 3710487 | 6937 | 0.016 | -0.0312 | No | ||
75 | SALL1 | 5420020 7050195 | 6955 | 0.016 | -0.0319 | No | ||
76 | SLC2A4 | 540441 | 7047 | 0.014 | -0.0367 | No | ||
77 | PAX3 | 50551 | 7369 | 0.009 | -0.0541 | No | ||
78 | ZFP36L1 | 2510138 4120048 | 7959 | -0.001 | -0.0860 | No | ||
79 | HOXD10 | 6100039 | 8242 | -0.006 | -0.1012 | No | ||
80 | KCNMB1 | 4760139 | 8306 | -0.006 | -0.1046 | No | ||
81 | ESR1 | 4060372 5860193 | 8512 | -0.010 | -0.1156 | No | ||
82 | ANXA9 | 1190195 | 8621 | -0.012 | -0.1213 | No | ||
83 | PDE5A | 130072 | 8804 | -0.015 | -0.1311 | No | ||
84 | LRRN1 | 3290154 | 8817 | -0.015 | -0.1316 | No | ||
85 | TIMP4 | 6110433 | 8892 | -0.016 | -0.1354 | No | ||
86 | NF1 | 6980433 | 8913 | -0.017 | -0.1363 | No | ||
87 | EVX1 | 1980471 | 9102 | -0.020 | -0.1464 | No | ||
88 | NFATC4 | 2470735 | 9158 | -0.021 | -0.1491 | No | ||
89 | FABP6 | 7000278 | 9231 | -0.022 | -0.1528 | No | ||
90 | LMX1A | 2810239 5690324 | 9374 | -0.025 | -0.1603 | No | ||
91 | GREM1 | 3940180 | 9722 | -0.030 | -0.1788 | No | ||
92 | HOXA11 | 6980133 | 9753 | -0.031 | -0.1801 | No | ||
93 | HIF1A | 5670605 | 9786 | -0.032 | -0.1816 | No | ||
94 | FBXO24 | 1230132 4610121 | 9861 | -0.033 | -0.1853 | No | ||
95 | ERF | 110551 1770278 | 10004 | -0.036 | -0.1926 | No | ||
96 | HOXC4 | 1940193 | 10070 | -0.038 | -0.1958 | No | ||
97 | RKHD3 | 6180471 | 10681 | -0.051 | -0.2284 | No | ||
98 | FADS3 | 3120079 | 11080 | -0.061 | -0.2494 | No | ||
99 | CRLF1 | 3520092 | 11152 | -0.062 | -0.2526 | No | ||
100 | PTRF | 2260204 | 11182 | -0.063 | -0.2536 | No | ||
101 | PKP3 | 3710048 | 11313 | -0.067 | -0.2600 | No | ||
102 | ATP6V0C | 1780609 | 11554 | -0.075 | -0.2723 | No | ||
103 | AGER | 5860538 5910180 | 11582 | -0.075 | -0.2730 | No | ||
104 | EPO | 940180 | 11661 | -0.078 | -0.2765 | No | ||
105 | KCNK7 | 4230576 | 11717 | -0.080 | -0.2787 | No | ||
106 | MT4 | 4780338 | 11785 | -0.083 | -0.2815 | No | ||
107 | DLGAP4 | 4570672 5690161 | 11817 | -0.083 | -0.2824 | No | ||
108 | MACF1 | 1340132 2370176 2900750 6590364 | 11913 | -0.087 | -0.2867 | No | ||
109 | NEUROD2 | 5290097 | 11941 | -0.088 | -0.2873 | No | ||
110 | FLNC | 2360048 5050270 | 11965 | -0.089 | -0.2877 | No | ||
111 | SMTN | 670563 1190438 | 12041 | -0.092 | -0.2909 | No | ||
112 | LGP2 | 4480338 | 12171 | -0.097 | -0.2970 | No | ||
113 | DPYSL2 | 2100427 3130112 5700324 | 12475 | -0.112 | -0.3123 | No | ||
114 | KLF12 | 1660095 4810288 5340546 6520286 | 12544 | -0.115 | -0.3149 | No | ||
115 | HOXA3 | 3610632 6020358 | 12646 | -0.121 | -0.3192 | No | ||
116 | BCL6B | 60047 | 12648 | -0.121 | -0.3181 | No | ||
117 | H2AFY | 4730750 | 13017 | -0.143 | -0.3367 | No | ||
118 | INPP4A | 510215 1090541 4850093 6100519 | 13239 | -0.159 | -0.3471 | No | ||
119 | TGFB1I1 | 2060288 6550450 | 13285 | -0.163 | -0.3480 | No | ||
120 | LRCH4 | 5220279 6510026 | 13501 | -0.181 | -0.3579 | No | ||
121 | ABCG4 | 3440458 | 13590 | -0.189 | -0.3608 | No | ||
122 | HOXB2 | 6450592 | 13804 | -0.210 | -0.3704 | No | ||
123 | LDLR | 5670386 | 13884 | -0.218 | -0.3726 | No | ||
124 | ATE1 | 290491 6940722 | 13937 | -0.224 | -0.3732 | No | ||
125 | PLCB3 | 4670402 | 13955 | -0.227 | -0.3720 | No | ||
126 | SYTL2 | 580097 5390576 6770603 | 14095 | -0.241 | -0.3772 | No | ||
127 | NRGN | 4280433 | 14115 | -0.244 | -0.3759 | No | ||
128 | A2BP1 | 2370390 4590593 5550014 | 14302 | -0.269 | -0.3834 | No | ||
129 | LPHN1 | 1400113 3130301 | 14510 | -0.301 | -0.3917 | No | ||
130 | IMPDH2 | 5220138 | 14567 | -0.313 | -0.3917 | No | ||
131 | NR1D1 | 2360471 770746 6590204 | 14570 | -0.313 | -0.3888 | No | ||
132 | TBCC | 4810021 | 14588 | -0.315 | -0.3867 | No | ||
133 | MAP1A | 4920576 | 14671 | -0.329 | -0.3879 | No | ||
134 | RPS10 | 4560673 | 14731 | -0.341 | -0.3879 | No | ||
135 | SLCO3A1 | 1050408 2370156 6110072 | 14869 | -0.363 | -0.3918 | No | ||
136 | DDR1 | 2060044 5220180 | 15087 | -0.411 | -0.3996 | No | ||
137 | PDGFB | 3060440 6370008 | 15107 | -0.414 | -0.3966 | No | ||
138 | TCF1 | 5390022 | 15199 | -0.435 | -0.3974 | No | ||
139 | PVRL1 | 2570167 5220519 5890500 3190309 | 15271 | -0.452 | -0.3969 | No | ||
140 | LBX1 | 1300164 4060204 | 15292 | -0.457 | -0.3936 | No | ||
141 | AP1G2 | 780458 2690068 | 15309 | -0.461 | -0.3900 | No | ||
142 | CLSTN3 | 2350685 | 15330 | -0.468 | -0.3866 | No | ||
143 | SYNPO2L | 5390719 | 15505 | -0.523 | -0.3910 | No | ||
144 | RAB10 | 2360008 5890020 | 15725 | -0.603 | -0.3970 | No | ||
145 | ITPR3 | 4010632 | 15789 | -0.624 | -0.3944 | No | ||
146 | SPI1 | 1410397 | 16074 | -0.748 | -0.4026 | No | ||
147 | DLK1 | 1240138 | 16382 | -0.888 | -0.4107 | Yes | ||
148 | CDC42EP4 | 4150338 | 16392 | -0.891 | -0.4026 | Yes | ||
149 | CLIC1 | 110600 | 16583 | -0.981 | -0.4035 | Yes | ||
150 | TYRO3 | 3130193 | 16609 | -0.993 | -0.3953 | Yes | ||
151 | IMMT | 870450 4280438 | 16611 | -0.993 | -0.3857 | Yes | ||
152 | PDXP | 5050204 460273 6040102 | 16625 | -0.996 | -0.3768 | Yes | ||
153 | RHOA | 580142 5900131 5340450 | 16637 | -0.998 | -0.3678 | Yes | ||
154 | HSPG2 | 2510687 6220750 | 16727 | -1.032 | -0.3627 | Yes | ||
155 | STAT6 | 1190010 5720019 | 16806 | -1.075 | -0.3566 | Yes | ||
156 | SSBP2 | 2260725 2900400 4730711 | 16927 | -1.151 | -0.3520 | Yes | ||
157 | ARHGDIB | 4730433 | 17043 | -1.226 | -0.3464 | Yes | ||
158 | PEX16 | 4560044 | 17119 | -1.267 | -0.3383 | Yes | ||
159 | NDRG2 | 450403 | 17220 | -1.340 | -0.3308 | Yes | ||
160 | MTMR3 | 1050014 4920180 | 17231 | -1.344 | -0.3184 | Yes | ||
161 | FOXP4 | 6290022 | 17276 | -1.373 | -0.3075 | Yes | ||
162 | DCTN1 | 1450056 6590022 | 17321 | -1.405 | -0.2964 | Yes | ||
163 | DNMT3B | 2320138 4070059 | 17436 | -1.482 | -0.2883 | Yes | ||
164 | MRPS18B | 5570086 | 17927 | -1.922 | -0.2963 | Yes | ||
165 | GRWD1 | 6350528 | 17999 | -2.004 | -0.2808 | Yes | ||
166 | MYL6 | 60563 6100152 | 18078 | -2.094 | -0.2649 | Yes | ||
167 | ARFIP2 | 1850301 4670180 | 18215 | -2.274 | -0.2503 | Yes | ||
168 | FXC1 | 3710053 4060575 | 18400 | -2.661 | -0.2347 | Yes | ||
169 | RHEBL1 | 2810576 | 18423 | -2.741 | -0.2095 | Yes | ||
170 | CEBPB | 2970019 | 18441 | -2.781 | -0.1836 | Yes | ||
171 | DTX1 | 5900372 | 18461 | -2.857 | -0.1571 | Yes | ||
172 | RHOG | 6760575 | 18532 | -3.188 | -0.1302 | Yes | ||
173 | ETV5 | 110017 | 18559 | -3.357 | -0.0992 | Yes | ||
174 | CORO1A | 3140609 3190020 3190037 | 18569 | -3.439 | -0.0666 | Yes | ||
175 | PTK2B | 4730411 | 18576 | -3.507 | -0.0331 | Yes | ||
176 | GNAS | 630441 1850373 4050152 | 18584 | -3.653 | 0.0017 | Yes |