Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$NFKB_Q6_01 |
Enrichment Score (ES) | -0.41840753 |
Normalized Enrichment Score (NES) | -1.2149974 |
Nominal p-value | 0.07402032 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | SIN3A | 2190121 | 191 | 2.561 | 0.0156 | No | ||
2 | UBE2D3 | 3190452 | 542 | 1.915 | 0.0160 | No | ||
3 | RAP2C | 1690132 | 588 | 1.868 | 0.0325 | No | ||
4 | UPF2 | 4810471 | 654 | 1.793 | 0.0471 | No | ||
5 | UACA | 1190725 | 742 | 1.708 | 0.0597 | No | ||
6 | ATP1B1 | 3130594 | 875 | 1.572 | 0.0685 | No | ||
7 | PRKCD | 770592 | 914 | 1.525 | 0.0818 | No | ||
8 | CYLD | 6590079 | 1155 | 1.276 | 0.0818 | No | ||
9 | BCL3 | 3990440 | 1412 | 1.061 | 0.0786 | No | ||
10 | REV3L | 1090717 | 1424 | 1.054 | 0.0887 | No | ||
11 | ICAM1 | 6980138 | 1452 | 1.039 | 0.0978 | No | ||
12 | PCBP4 | 6350722 | 1563 | 0.991 | 0.1018 | No | ||
13 | RBMS1 | 6400014 | 1665 | 0.929 | 0.1058 | No | ||
14 | NFAT5 | 2510411 5890195 6550152 | 1871 | 0.804 | 0.1028 | No | ||
15 | RALGDS | 430463 | 1952 | 0.757 | 0.1062 | No | ||
16 | XPO6 | 3940019 | 2073 | 0.683 | 0.1066 | No | ||
17 | BMF | 610102 | 2098 | 0.672 | 0.1121 | No | ||
18 | SMOC1 | 840039 | 2106 | 0.670 | 0.1185 | No | ||
19 | AMOTL1 | 380279 | 2150 | 0.646 | 0.1227 | No | ||
20 | IL12A | 7100551 | 2283 | 0.588 | 0.1215 | No | ||
21 | EGF | 5220154 | 2474 | 0.515 | 0.1164 | No | ||
22 | USP52 | 3710215 6380133 | 2509 | 0.502 | 0.1197 | No | ||
23 | NR3C1 | 630563 | 2601 | 0.470 | 0.1195 | No | ||
24 | SOCS2 | 4760692 | 2633 | 0.461 | 0.1225 | No | ||
25 | GNB1 | 2120397 | 2641 | 0.459 | 0.1267 | No | ||
26 | IL6ST | 5890047 | 2796 | 0.409 | 0.1225 | No | ||
27 | COL27A1 | 1740390 | 2892 | 0.375 | 0.1212 | No | ||
28 | CREB1 | 1500717 2230358 3610600 6550601 | 2898 | 0.374 | 0.1247 | No | ||
29 | TCEA2 | 6370546 | 2902 | 0.373 | 0.1283 | No | ||
30 | CD69 | 380167 4730088 | 3135 | 0.303 | 0.1188 | No | ||
31 | SHOX2 | 3190438 6450059 | 3233 | 0.282 | 0.1164 | No | ||
32 | DUSP22 | 4280010 5550546 | 3316 | 0.263 | 0.1146 | No | ||
33 | ZIC4 | 1500082 | 3339 | 0.256 | 0.1160 | No | ||
34 | BLR1 | 1500300 5420017 | 3341 | 0.256 | 0.1186 | No | ||
35 | HIVEP1 | 3850632 | 3407 | 0.245 | 0.1175 | No | ||
36 | NLK | 2030010 2450041 | 3455 | 0.233 | 0.1173 | No | ||
37 | ASCL3 | 4570484 | 3989 | 0.149 | 0.0900 | No | ||
38 | ERN1 | 2360403 | 4031 | 0.143 | 0.0892 | No | ||
39 | ZNRF1 | 70592 | 4170 | 0.130 | 0.0830 | No | ||
40 | BIRC3 | 6550411 | 4236 | 0.125 | 0.0808 | No | ||
41 | WNT10A | 2100706 | 4269 | 0.122 | 0.0803 | No | ||
42 | KLK9 | 4120164 | 4409 | 0.109 | 0.0738 | No | ||
43 | HTR3B | 430438 520301 | 4418 | 0.108 | 0.0745 | No | ||
44 | TRAF4 | 3060041 4920528 6980286 | 4421 | 0.107 | 0.0755 | No | ||
45 | FGF17 | 3130022 | 4451 | 0.106 | 0.0750 | No | ||
46 | TBX20 | 2230279 4920102 6980020 | 4461 | 0.105 | 0.0756 | No | ||
47 | RFX5 | 5420128 | 4607 | 0.095 | 0.0687 | No | ||
48 | CHD4 | 5420059 6130338 6380717 | 4637 | 0.093 | 0.0680 | No | ||
49 | ELMO1 | 110338 1190451 1580148 1850609 2350706 2370369 2450129 3840113 4150184 4280079 6290066 6380435 6770494 7100180 | 4701 | 0.089 | 0.0655 | No | ||
50 | UBD | 5570632 | 4753 | 0.086 | 0.0636 | No | ||
51 | GNG4 | 2630600 | 4770 | 0.085 | 0.0636 | No | ||
52 | GRIN2D | 6620372 | 4791 | 0.083 | 0.0634 | No | ||
53 | EDN2 | 6760647 | 4940 | 0.076 | 0.0561 | No | ||
54 | BAI2 | 380632 630113 6650170 | 5536 | 0.051 | 0.0244 | No | ||
55 | NR2F2 | 3170609 3310577 | 5628 | 0.048 | 0.0199 | No | ||
56 | UBE2I | 2680056 6350446 | 5662 | 0.047 | 0.0186 | No | ||
57 | BDNF | 2940128 3520368 | 5956 | 0.038 | 0.0031 | No | ||
58 | MITF | 380056 | 6574 | 0.024 | -0.0301 | No | ||
59 | AP1S2 | 780279 4280707 | 6958 | 0.016 | -0.0507 | No | ||
60 | IL23A | 6290044 | 7103 | 0.013 | -0.0583 | No | ||
61 | PTPRJ | 4010707 | 7634 | 0.004 | -0.0870 | No | ||
62 | IL1RN | 2370333 | 7976 | -0.001 | -0.1055 | No | ||
63 | MADCAM1 | 1580010 | 8059 | -0.003 | -0.1099 | No | ||
64 | IL7 | 5360440 | 8186 | -0.005 | -0.1167 | No | ||
65 | MSX1 | 2650309 | 8255 | -0.006 | -0.1203 | No | ||
66 | RIN2 | 2450184 | 8323 | -0.007 | -0.1239 | No | ||
67 | EHF | 4560088 | 8646 | -0.012 | -0.1412 | No | ||
68 | SLC6A12 | 3170685 | 8952 | -0.018 | -0.1575 | No | ||
69 | GREM1 | 3940180 | 9722 | -0.030 | -0.1989 | No | ||
70 | GATA4 | 1410215 2690609 | 10033 | -0.037 | -0.2153 | No | ||
71 | ARHGEF2 | 3360577 | 10092 | -0.038 | -0.2181 | No | ||
72 | PHOX2B | 5270075 | 10099 | -0.038 | -0.2180 | No | ||
73 | FGF1 | 4780435 5670601 | 10272 | -0.041 | -0.2269 | No | ||
74 | ALG6 | 4060131 | 10768 | -0.053 | -0.2532 | No | ||
75 | NTN1 | 5700600 | 10809 | -0.054 | -0.2548 | No | ||
76 | IL27 | 1990324 | 10879 | -0.056 | -0.2580 | No | ||
77 | TNFSF15 | 360341 | 10898 | -0.056 | -0.2584 | No | ||
78 | HSD11B2 | 5900053 | 10987 | -0.058 | -0.2626 | No | ||
79 | ZBTB11 | 6520092 | 11299 | -0.067 | -0.2788 | No | ||
80 | TSLP | 730408 1990500 | 11360 | -0.069 | -0.2813 | No | ||
81 | IER5 | 2350575 | 11613 | -0.076 | -0.2942 | No | ||
82 | GABRB1 | 6760193 | 11624 | -0.076 | -0.2940 | No | ||
83 | ETV1 | 70735 2940603 5080463 | 11678 | -0.079 | -0.2960 | No | ||
84 | FTHL17 | 6550193 | 11733 | -0.080 | -0.2982 | No | ||
85 | RASSF2 | 2480079 5720546 | 11794 | -0.083 | -0.3006 | No | ||
86 | LTA | 1740088 | 11847 | -0.085 | -0.3025 | No | ||
87 | C1QL1 | 2030465 | 11892 | -0.086 | -0.3040 | No | ||
88 | SP6 | 60484 510452 2690333 | 12130 | -0.096 | -0.3159 | No | ||
89 | IFNB1 | 1400142 | 12299 | -0.104 | -0.3240 | No | ||
90 | POU2F3 | 2030601 | 12520 | -0.114 | -0.3347 | No | ||
91 | PPP1R13B | 4010605 4760181 | 12552 | -0.116 | -0.3352 | No | ||
92 | BCL6B | 60047 | 12648 | -0.121 | -0.3392 | No | ||
93 | MOBKL2C | 2640088 3830017 | 12668 | -0.122 | -0.3390 | No | ||
94 | SMPD3 | 520164 | 12801 | -0.130 | -0.3448 | No | ||
95 | BMP2K | 60541 5570504 | 12863 | -0.133 | -0.3468 | No | ||
96 | TNFRSF9 | 2510400 6650484 | 12915 | -0.137 | -0.3481 | No | ||
97 | HSD3B7 | 1410129 | 13019 | -0.143 | -0.3523 | No | ||
98 | PTGES | 1690075 | 13063 | -0.147 | -0.3531 | No | ||
99 | DAP3 | 1660528 2120039 5420593 | 13126 | -0.151 | -0.3549 | No | ||
100 | FUT7 | 2900736 | 13420 | -0.173 | -0.3691 | No | ||
101 | CNTNAP1 | 6650132 | 13457 | -0.177 | -0.3692 | No | ||
102 | CSF3 | 2230193 6660707 | 13498 | -0.181 | -0.3696 | No | ||
103 | SNAP25 | 360520 | 13520 | -0.183 | -0.3688 | No | ||
104 | GRK5 | 1940348 4670053 | 13601 | -0.190 | -0.3712 | No | ||
105 | PAPPA | 4230463 | 13720 | -0.202 | -0.3756 | No | ||
106 | SEMA3B | 5570563 | 13726 | -0.202 | -0.3738 | No | ||
107 | TNFSF18 | 1990458 2850520 | 13926 | -0.222 | -0.3823 | No | ||
108 | IL13 | 7040021 | 14026 | -0.235 | -0.3853 | No | ||
109 | PTHLH | 5290739 | 14223 | -0.260 | -0.3933 | No | ||
110 | RND1 | 5080300 | 14247 | -0.264 | -0.3919 | No | ||
111 | SOX5 | 2370576 2900167 3190128 5050528 | 14287 | -0.268 | -0.3913 | No | ||
112 | TRIM47 | 5080717 | 14403 | -0.283 | -0.3947 | No | ||
113 | PCSK2 | 360017 430528 5900619 | 14430 | -0.287 | -0.3932 | No | ||
114 | SLAMF8 | 1230048 | 14557 | -0.310 | -0.3969 | No | ||
115 | DUSP6 | 5910286 7100070 | 14628 | -0.323 | -0.3974 | No | ||
116 | DCAMKL1 | 540095 2690092 | 14896 | -0.369 | -0.4081 | No | ||
117 | DDR1 | 2060044 5220180 | 15087 | -0.411 | -0.4142 | Yes | ||
118 | MAG | 2370037 | 15125 | -0.419 | -0.4120 | Yes | ||
119 | TCF1 | 5390022 | 15199 | -0.435 | -0.4116 | Yes | ||
120 | TP53 | 6130707 | 15236 | -0.442 | -0.4090 | Yes | ||
121 | MMP9 | 580338 | 15380 | -0.483 | -0.4119 | Yes | ||
122 | TNFRSF1B | 3990035 5860372 | 15464 | -0.510 | -0.4112 | Yes | ||
123 | TNIP1 | 2510279 5900041 6510435 | 15490 | -0.519 | -0.4073 | Yes | ||
124 | CENTB5 | 5690128 | 15575 | -0.547 | -0.4063 | Yes | ||
125 | GPHN | 3290195 3840121 | 15607 | -0.562 | -0.4023 | Yes | ||
126 | ASH1L | 2510402 5360687 6650685 | 15870 | -0.652 | -0.4099 | Yes | ||
127 | KRTAP13-1 | 2600242 | 15894 | -0.662 | -0.4045 | Yes | ||
128 | NFKBIB | 2260167 | 16064 | -0.743 | -0.4061 | Yes | ||
129 | GADD45B | 2350408 | 16116 | -0.766 | -0.4011 | Yes | ||
130 | VCAM1 | 2900450 | 16311 | -0.852 | -0.4030 | Yes | ||
131 | CLCN1 | 840161 | 16324 | -0.858 | -0.3949 | Yes | ||
132 | EDG5 | 2640300 | 16479 | -0.930 | -0.3939 | Yes | ||
133 | RASGRP4 | 540102 | 16515 | -0.945 | -0.3862 | Yes | ||
134 | ENO3 | 5270136 | 16556 | -0.967 | -0.3786 | Yes | ||
135 | TOP1 | 770471 4060632 6650324 | 16558 | -0.968 | -0.3688 | Yes | ||
136 | MSC | 5080139 | 16663 | -1.005 | -0.3643 | Yes | ||
137 | LTB | 3990672 | 16691 | -1.016 | -0.3554 | Yes | ||
138 | NFKB2 | 2320670 | 16799 | -1.069 | -0.3504 | Yes | ||
139 | STAT6 | 1190010 5720019 | 16806 | -1.075 | -0.3399 | Yes | ||
140 | NFKBIA | 1570152 | 16859 | -1.101 | -0.3315 | Yes | ||
141 | PFN1 | 6130132 | 16915 | -1.144 | -0.3229 | Yes | ||
142 | EBI3 | 5340300 | 16967 | -1.172 | -0.3138 | Yes | ||
143 | MAP3K11 | 7000039 | 17023 | -1.210 | -0.3046 | Yes | ||
144 | SEC61A1 | 3390437 | 17041 | -1.225 | -0.2931 | Yes | ||
145 | JAK3 | 70347 3290008 | 17108 | -1.262 | -0.2839 | Yes | ||
146 | SIRT2 | 630494 | 17129 | -1.273 | -0.2721 | Yes | ||
147 | TRIB2 | 4120605 | 17181 | -1.321 | -0.2614 | Yes | ||
148 | NDRG2 | 450403 | 17220 | -1.340 | -0.2499 | Yes | ||
149 | CCL5 | 3710397 | 17387 | -1.453 | -0.2442 | Yes | ||
150 | ILK | 870601 4480180 | 17416 | -1.471 | -0.2308 | Yes | ||
151 | MAP4K2 | 4200037 | 17435 | -1.482 | -0.2168 | Yes | ||
152 | UBE2H | 1980142 2970079 | 17455 | -1.491 | -0.2027 | Yes | ||
153 | RELB | 1400048 | 17499 | -1.525 | -0.1896 | Yes | ||
154 | EIF5A | 1500059 5290022 6370026 | 17518 | -1.536 | -0.1750 | Yes | ||
155 | IL4I1 | 3190161 | 17569 | -1.578 | -0.1618 | Yes | ||
156 | NEK8 | 5700180 | 17746 | -1.739 | -0.1537 | Yes | ||
157 | IL27RA | 940093 | 17872 | -1.864 | -0.1416 | Yes | ||
158 | FBXL12 | 2230040 3520008 | 18094 | -2.115 | -0.1322 | Yes | ||
159 | MRPS6 | 870164 | 18251 | -2.339 | -0.1169 | Yes | ||
160 | IL2RA | 6620450 | 18426 | -2.744 | -0.0986 | Yes | ||
161 | RHOG | 6760575 | 18532 | -3.188 | -0.0720 | Yes | ||
162 | ARHGAP8 | 380333 5390487 | 18563 | -3.405 | -0.0391 | Yes | ||
163 | BATF | 6760390 | 18597 | -4.143 | 0.0010 | Yes |