Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$LFA1_Q6 |
Enrichment Score (ES) | -0.4514202 |
Normalized Enrichment Score (NES) | -1.3212876 |
Nominal p-value | 0.011204482 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | ARID1A | 2630022 1690551 4810110 | 78 | 2.995 | 0.0235 | No | ||
2 | EMILIN1 | 2190402 | 178 | 2.597 | 0.0421 | No | ||
3 | UBL3 | 6450458 | 327 | 2.259 | 0.0550 | No | ||
4 | BCL6 | 940100 | 355 | 2.213 | 0.0740 | No | ||
5 | NXF1 | 1570377 | 454 | 2.053 | 0.0877 | No | ||
6 | ZFPM1 | 6760093 | 603 | 1.858 | 0.0969 | No | ||
7 | UPF2 | 4810471 | 654 | 1.793 | 0.1107 | No | ||
8 | CCNL1 | 130273 | 674 | 1.776 | 0.1262 | No | ||
9 | BCL11B | 2680673 | 746 | 1.704 | 0.1381 | No | ||
10 | NPC2 | 2350102 | 899 | 1.546 | 0.1441 | No | ||
11 | PYGO2 | 360494 | 1111 | 1.326 | 0.1450 | No | ||
12 | FLI1 | 3990142 | 1167 | 1.266 | 0.1537 | No | ||
13 | DLX1 | 360168 | 1298 | 1.151 | 0.1573 | No | ||
14 | GSK3B | 5360348 | 1347 | 1.119 | 0.1650 | No | ||
15 | NFAT5 | 2510411 5890195 6550152 | 1871 | 0.804 | 0.1441 | No | ||
16 | CXCR4 | 4590519 | 2064 | 0.686 | 0.1401 | No | ||
17 | PCBP2 | 5690048 | 2092 | 0.675 | 0.1448 | No | ||
18 | RBBP6 | 2320129 | 2142 | 0.650 | 0.1482 | No | ||
19 | CKB | 4560632 | 2171 | 0.636 | 0.1526 | No | ||
20 | LZTS2 | 2260440 | 2173 | 0.635 | 0.1584 | No | ||
21 | BACE1 | 2650438 | 2275 | 0.592 | 0.1584 | No | ||
22 | FES | 3120129 5550600 | 2485 | 0.511 | 0.1518 | No | ||
23 | FKBP2 | 2320025 | 2720 | 0.434 | 0.1431 | No | ||
24 | ELF4 | 4850193 | 3035 | 0.330 | 0.1291 | No | ||
25 | PHF12 | 870400 3130687 | 3125 | 0.306 | 0.1271 | No | ||
26 | PNOC | 1990114 | 3143 | 0.300 | 0.1290 | No | ||
27 | NR5A2 | 1690180 6900050 | 3494 | 0.226 | 0.1121 | No | ||
28 | BRPF1 | 3170139 | 3504 | 0.224 | 0.1137 | No | ||
29 | ARID4A | 520156 1050707 | 3736 | 0.183 | 0.1028 | No | ||
30 | CNKSR2 | 110348 1770372 | 3738 | 0.183 | 0.1045 | No | ||
31 | RBM12 | 4570239 6040411 6660129 | 3764 | 0.179 | 0.1048 | No | ||
32 | CPNE1 | 3440131 | 3975 | 0.150 | 0.0948 | No | ||
33 | PRRX1 | 4120193 4480390 | 3993 | 0.149 | 0.0952 | No | ||
34 | LRP8 | 3610746 5360035 | 4248 | 0.123 | 0.0826 | No | ||
35 | KCNAB1 | 1580070 3290156 | 4376 | 0.112 | 0.0768 | No | ||
36 | KLK9 | 4120164 | 4409 | 0.109 | 0.0760 | No | ||
37 | HOXC6 | 3850133 4920736 | 4441 | 0.106 | 0.0753 | No | ||
38 | TAL1 | 7040239 | 4446 | 0.106 | 0.0761 | No | ||
39 | PAX7 | 6860593 | 4494 | 0.102 | 0.0745 | No | ||
40 | FXYD3 | 2320450 | 4635 | 0.093 | 0.0678 | No | ||
41 | OBSCN | 3610129 | 4759 | 0.085 | 0.0619 | No | ||
42 | IL1F10 | 2260647 | 4944 | 0.076 | 0.0526 | No | ||
43 | DHH | 2120433 | 5002 | 0.073 | 0.0502 | No | ||
44 | FLT1 | 3830167 4920438 | 5111 | 0.068 | 0.0450 | No | ||
45 | CASQ2 | 3170136 | 5271 | 0.061 | 0.0369 | No | ||
46 | NYX | 4120239 | 5300 | 0.060 | 0.0359 | No | ||
47 | NGFB | 2630019 | 5470 | 0.054 | 0.0273 | No | ||
48 | TSP50 | 6100593 | 5653 | 0.047 | 0.0178 | No | ||
49 | LIN28 | 6590672 | 5814 | 0.042 | 0.0096 | No | ||
50 | NPAS3 | 630408 4610066 | 6009 | 0.037 | -0.0006 | No | ||
51 | NEUROG1 | 380341 | 6051 | 0.035 | -0.0025 | No | ||
52 | CLTC | 6590458 | 6200 | 0.032 | -0.0103 | No | ||
53 | KCNQ4 | 3800438 7050400 | 6222 | 0.032 | -0.0111 | No | ||
54 | THRAP1 | 2470121 | 6434 | 0.027 | -0.0223 | No | ||
55 | SIX4 | 6760022 | 6435 | 0.027 | -0.0220 | No | ||
56 | OLFML2A | 5890039 | 6508 | 0.025 | -0.0257 | No | ||
57 | GNAO1 | 2510292 6590487 | 6769 | 0.020 | -0.0396 | No | ||
58 | CACNB1 | 2940427 3710487 | 6937 | 0.016 | -0.0485 | No | ||
59 | SALL1 | 5420020 7050195 | 6955 | 0.016 | -0.0493 | No | ||
60 | S100A5 | 4120592 | 6970 | 0.016 | -0.0499 | No | ||
61 | SP7 | 1050315 | 7005 | 0.015 | -0.0516 | No | ||
62 | SLC2A4 | 540441 | 7047 | 0.014 | -0.0537 | No | ||
63 | CRMP1 | 4810014 | 7839 | 0.001 | -0.0966 | No | ||
64 | PLA2G10 | 3060605 | 7845 | 0.001 | -0.0969 | No | ||
65 | SLC7A10 | 5570411 | 7898 | -0.000 | -0.0997 | No | ||
66 | AKT3 | 1580270 3290278 | 7974 | -0.001 | -0.1037 | No | ||
67 | EDG1 | 4200619 | 7994 | -0.002 | -0.1048 | No | ||
68 | PPY | 2340373 | 8231 | -0.005 | -0.1175 | No | ||
69 | MSX1 | 2650309 | 8255 | -0.006 | -0.1187 | No | ||
70 | BOC | 5270348 | 8264 | -0.006 | -0.1191 | No | ||
71 | DUOX2 | 1410575 | 8350 | -0.007 | -0.1236 | No | ||
72 | MGEA5 | 6100014 | 8459 | -0.009 | -0.1294 | No | ||
73 | RAB5C | 1990397 | 8476 | -0.009 | -0.1302 | No | ||
74 | OTOP2 | 610068 | 8617 | -0.012 | -0.1376 | No | ||
75 | LMOD3 | 2120524 | 8647 | -0.012 | -0.1391 | No | ||
76 | CHX10 | 3830184 | 8720 | -0.014 | -0.1429 | No | ||
77 | ACVR1C | 5890044 | 9080 | -0.020 | -0.1622 | No | ||
78 | GPR4 | 2060358 | 9266 | -0.023 | -0.1720 | No | ||
79 | ACCN1 | 2060139 2190541 | 9409 | -0.025 | -0.1795 | No | ||
80 | PAK1IP1 | 2230438 | 9446 | -0.026 | -0.1812 | No | ||
81 | RFX4 | 3710100 5340215 | 9454 | -0.026 | -0.1813 | No | ||
82 | WNT4 | 4150619 | 9755 | -0.031 | -0.1973 | No | ||
83 | XYLT1 | 6550403 | 9798 | -0.032 | -0.1993 | No | ||
84 | NACA | 520326 5890673 | 9919 | -0.035 | -0.2055 | No | ||
85 | HNRPR | 2320440 2900601 4610008 | 10044 | -0.037 | -0.2118 | No | ||
86 | DPF2 | 6980373 | 10326 | -0.043 | -0.2267 | No | ||
87 | MYBPH | 2190711 | 10590 | -0.049 | -0.2405 | No | ||
88 | CAV1 | 870025 | 10632 | -0.050 | -0.2423 | No | ||
89 | NPTXR | 4060685 450438 | 10749 | -0.052 | -0.2481 | No | ||
90 | NR4A1 | 6290161 | 10821 | -0.054 | -0.2514 | No | ||
91 | USH1G | 2940446 | 10863 | -0.055 | -0.2531 | No | ||
92 | NKX2-3 | 1990736 6940088 | 10896 | -0.056 | -0.2543 | No | ||
93 | BNC2 | 4810603 | 10897 | -0.056 | -0.2538 | No | ||
94 | SMARCD2 | 3830619 | 10969 | -0.058 | -0.2571 | No | ||
95 | SEMA6A | 2690138 3060021 | 11083 | -0.061 | -0.2627 | No | ||
96 | PTRF | 2260204 | 11182 | -0.063 | -0.2674 | No | ||
97 | HARS2 | 1400215 2640471 | 11229 | -0.065 | -0.2693 | No | ||
98 | ADAMTS4 | 430435 | 11306 | -0.067 | -0.2728 | No | ||
99 | TNRC4 | 4050156 | 11487 | -0.072 | -0.2819 | No | ||
100 | GBA2 | 2900372 | 11549 | -0.074 | -0.2845 | No | ||
101 | JPH4 | 780020 | 11593 | -0.076 | -0.2862 | No | ||
102 | TPCN1 | 60458 6510731 6860601 | 11605 | -0.076 | -0.2861 | No | ||
103 | EPO | 940180 | 11661 | -0.078 | -0.2883 | No | ||
104 | ETV1 | 70735 2940603 5080463 | 11678 | -0.079 | -0.2885 | No | ||
105 | GRIN2A | 6550538 | 11714 | -0.080 | -0.2896 | No | ||
106 | DLGAP4 | 4570672 5690161 | 11817 | -0.083 | -0.2944 | No | ||
107 | CLIC5 | 6900338 | 12116 | -0.095 | -0.3097 | No | ||
108 | CACNA1G | 3060161 4810706 5550722 | 12178 | -0.098 | -0.3121 | No | ||
109 | POU4F1 | 2260315 | 12389 | -0.108 | -0.3225 | No | ||
110 | M6PR | 2480458 3290593 3840324 | 12487 | -0.112 | -0.3267 | No | ||
111 | CREB3L2 | 3390484 | 12612 | -0.119 | -0.3323 | No | ||
112 | RABGGTA | 3190484 4070195 | 12693 | -0.123 | -0.3355 | No | ||
113 | PALM | 130601 3850017 | 12818 | -0.131 | -0.3410 | No | ||
114 | CTGF | 4540577 | 12887 | -0.135 | -0.3435 | No | ||
115 | LCAT | 6400441 | 12914 | -0.137 | -0.3436 | No | ||
116 | GPR3 | 2970452 | 13256 | -0.161 | -0.3606 | No | ||
117 | MYOG | 3190672 | 13682 | -0.198 | -0.3818 | No | ||
118 | HOXC10 | 5360170 | 13849 | -0.215 | -0.3888 | No | ||
119 | ZNF385 | 450176 4810358 | 13984 | -0.230 | -0.3940 | No | ||
120 | ANXA4 | 1400315 | 14058 | -0.237 | -0.3957 | No | ||
121 | GAD1 | 2360035 3140167 | 14087 | -0.240 | -0.3950 | No | ||
122 | NRGN | 4280433 | 14115 | -0.244 | -0.3942 | No | ||
123 | SOX5 | 2370576 2900167 3190128 5050528 | 14287 | -0.268 | -0.4010 | No | ||
124 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 14365 | -0.276 | -0.4026 | No | ||
125 | TBR1 | 5130053 | 14489 | -0.297 | -0.4066 | No | ||
126 | RHO | 4280398 | 14630 | -0.323 | -0.4112 | No | ||
127 | KIF1C | 2480484 | 14632 | -0.323 | -0.4082 | No | ||
128 | TITF1 | 3390554 4540292 | 14772 | -0.346 | -0.4126 | No | ||
129 | GABRG2 | 2350402 4210204 6130279 6550037 | 14783 | -0.348 | -0.4099 | No | ||
130 | SH3BP1 | 3450075 6350288 | 14823 | -0.354 | -0.4087 | No | ||
131 | MOV10 | 50673 430577 3870280 | 14858 | -0.362 | -0.4072 | No | ||
132 | SLC13A5 | 5810615 | 14961 | -0.384 | -0.4092 | No | ||
133 | STOML2 | 1940487 | 15306 | -0.461 | -0.4236 | No | ||
134 | SLC26A9 | 3440722 5340088 7510093 | 15372 | -0.481 | -0.4227 | No | ||
135 | TRIP10 | 460438 | 15706 | -0.596 | -0.4352 | No | ||
136 | MCRS1 | 110121 2340592 5270484 | 15748 | -0.610 | -0.4318 | No | ||
137 | UQCRC1 | 520053 | 15796 | -0.627 | -0.4285 | No | ||
138 | GABARAP | 1450286 | 15845 | -0.640 | -0.4252 | No | ||
139 | CIC | 6370161 | 16329 | -0.861 | -0.4435 | Yes | ||
140 | HIRA | 4480609 5270167 | 16394 | -0.892 | -0.4387 | Yes | ||
141 | EFNA3 | 6370390 | 16434 | -0.907 | -0.4324 | Yes | ||
142 | LAG3 | 6860112 | 16441 | -0.911 | -0.4243 | Yes | ||
143 | NEURL | 5390538 | 16543 | -0.962 | -0.4209 | Yes | ||
144 | IMMT | 870450 4280438 | 16611 | -0.993 | -0.4153 | Yes | ||
145 | EPHB2 | 1090288 1410377 2100541 | 16627 | -0.997 | -0.4069 | Yes | ||
146 | PDYN | 5720408 | 16654 | -1.003 | -0.3990 | Yes | ||
147 | NFKBIA | 1570152 | 16859 | -1.101 | -0.3999 | Yes | ||
148 | VASP | 7050500 | 16921 | -1.147 | -0.3926 | Yes | ||
149 | SESN3 | 110687 | 16981 | -1.181 | -0.3849 | Yes | ||
150 | MNT | 4920575 | 17009 | -1.202 | -0.3752 | Yes | ||
151 | RAB4B | 1770204 | 17013 | -1.205 | -0.3642 | Yes | ||
152 | ADM | 4810121 | 17111 | -1.264 | -0.3578 | Yes | ||
153 | GSS | 6130465 6900398 | 17138 | -1.284 | -0.3473 | Yes | ||
154 | ROM1 | 3130685 | 17274 | -1.373 | -0.3419 | Yes | ||
155 | DCTN1 | 1450056 6590022 | 17321 | -1.405 | -0.3314 | Yes | ||
156 | MRPL40 | 2370215 | 17347 | -1.424 | -0.3196 | Yes | ||
157 | PPP1R16A | 5080239 | 17356 | -1.428 | -0.3068 | Yes | ||
158 | RASGRP2 | 2970333 | 17545 | -1.563 | -0.3026 | Yes | ||
159 | COX7A2L | 1500142 | 17620 | -1.621 | -0.2916 | Yes | ||
160 | SLC25A29 | 5080095 | 17632 | -1.632 | -0.2771 | Yes | ||
161 | MAZ | 3360121 6940750 | 17767 | -1.755 | -0.2681 | Yes | ||
162 | NDUFS2 | 4850020 6200402 | 17779 | -1.771 | -0.2523 | Yes | ||
163 | NCDN | 50040 1980739 3520603 | 17871 | -1.864 | -0.2400 | Yes | ||
164 | CNN2 | 2230433 5270446 | 17910 | -1.904 | -0.2245 | Yes | ||
165 | PDLIM7 | 4780136 | 17992 | -1.999 | -0.2104 | Yes | ||
166 | ZFP36 | 2030605 | 18134 | -2.159 | -0.1980 | Yes | ||
167 | SMAD3 | 6450671 | 18195 | -2.238 | -0.1806 | Yes | ||
168 | BAX | 3830008 | 18200 | -2.252 | -0.1600 | Yes | ||
169 | TCF7 | 3800736 5390181 | 18208 | -2.262 | -0.1394 | Yes | ||
170 | HEBP1 | 6100279 | 18216 | -2.276 | -0.1187 | Yes | ||
171 | HES1 | 4810280 | 18347 | -2.504 | -0.1026 | Yes | ||
172 | CEBPB | 2970019 | 18441 | -2.781 | -0.0819 | Yes | ||
173 | RHOG | 6760575 | 18532 | -3.188 | -0.0573 | Yes | ||
174 | IFRD2 | 4150110 | 18553 | -3.299 | -0.0279 | Yes | ||
175 | POLD4 | 2320082 | 18561 | -3.377 | 0.0030 | Yes |