Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | truncNotch |
GeneSet | V$E12_Q6 |
Enrichment Score (ES) | -0.44777986 |
Normalized Enrichment Score (NES) | -1.3121161 |
Nominal p-value | 0.022889843 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | NEDD4L | 6380368 | 105 | 2.841 | 0.0243 | No | ||
2 | RRAGC | 5910348 | 212 | 2.517 | 0.0452 | No | ||
3 | EGLN1 | 2480180 3120253 6110195 | 361 | 2.198 | 0.0604 | No | ||
4 | OSR1 | 1500025 | 710 | 1.738 | 0.0599 | No | ||
5 | RUNX1 | 3840711 | 910 | 1.531 | 0.0652 | No | ||
6 | PLAGL2 | 1770148 | 1044 | 1.390 | 0.0727 | No | ||
7 | SLC23A2 | 6660722 | 1054 | 1.380 | 0.0868 | No | ||
8 | NUP88 | 2510044 6760180 | 1205 | 1.238 | 0.0918 | No | ||
9 | MFNG | 1770242 4280348 | 1468 | 1.029 | 0.0884 | No | ||
10 | TPM3 | 670600 3170296 5670167 6650471 | 1548 | 0.998 | 0.0947 | No | ||
11 | CFL1 | 2340735 | 1650 | 0.941 | 0.0991 | No | ||
12 | LRP10 | 1580128 | 1727 | 0.890 | 0.1044 | No | ||
13 | HMGN2 | 3140091 | 1900 | 0.789 | 0.1034 | No | ||
14 | GRB2 | 6650398 | 2049 | 0.690 | 0.1027 | No | ||
15 | LNX2 | 3130025 | 2169 | 0.636 | 0.1030 | No | ||
16 | WNT6 | 4570364 | 2225 | 0.610 | 0.1064 | No | ||
17 | SORT1 | 1850242 2320632 3870537 | 2234 | 0.608 | 0.1124 | No | ||
18 | NTRK3 | 4050687 4070167 4610026 6100484 | 2582 | 0.477 | 0.0986 | No | ||
19 | TGFB3 | 1070041 | 2702 | 0.438 | 0.0968 | No | ||
20 | PACSIN3 | 4540369 4540400 5360037 6940129 | 2921 | 0.367 | 0.0889 | No | ||
21 | EYA3 | 1580195 6510632 | 2980 | 0.348 | 0.0894 | No | ||
22 | CAMK2A | 1740333 1940112 4150292 | 3064 | 0.322 | 0.0883 | No | ||
23 | CAMK1D | 1660100 2350309 | 3375 | 0.251 | 0.0741 | No | ||
24 | RIN1 | 510593 | 3421 | 0.241 | 0.0742 | No | ||
25 | ADAM12 | 3390132 4070347 | 3511 | 0.222 | 0.0718 | No | ||
26 | TRIM23 | 580168 6510672 | 3521 | 0.219 | 0.0736 | No | ||
27 | WDR20 | 1240373 | 3796 | 0.174 | 0.0606 | No | ||
28 | EIF2C1 | 6900551 | 3843 | 0.168 | 0.0599 | No | ||
29 | CDH5 | 5340487 | 3980 | 0.150 | 0.0541 | No | ||
30 | CNNM2 | 2650100 | 4018 | 0.145 | 0.0536 | No | ||
31 | SSH2 | 360056 | 4039 | 0.142 | 0.0540 | No | ||
32 | ASB14 | 5860427 | 4192 | 0.128 | 0.0471 | No | ||
33 | TNFAIP1 | 6940593 | 4336 | 0.115 | 0.0406 | No | ||
34 | CHRDL1 | 1580037 6380204 | 4354 | 0.114 | 0.0409 | No | ||
35 | COL4A4 | 1050541 | 4482 | 0.103 | 0.0351 | No | ||
36 | ITGA6 | 3830129 | 4521 | 0.100 | 0.0341 | No | ||
37 | ELMO1 | 110338 1190451 1580148 1850609 2350706 2370369 2450129 3840113 4150184 4280079 6290066 6380435 6770494 7100180 | 4701 | 0.089 | 0.0253 | No | ||
38 | SIM1 | 1770332 | 4763 | 0.085 | 0.0229 | No | ||
39 | NTRK2 | 6220463 | 4806 | 0.083 | 0.0215 | No | ||
40 | RAB26 | 5910025 | 4827 | 0.082 | 0.0213 | No | ||
41 | PIM2 | 840136 5720692 7100577 | 4931 | 0.076 | 0.0165 | No | ||
42 | KCNN3 | 6520600 6420138 | 5078 | 0.069 | 0.0093 | No | ||
43 | SOX17 | 5270551 | 5128 | 0.067 | 0.0073 | No | ||
44 | HR | 2690095 6200300 | 5136 | 0.067 | 0.0077 | No | ||
45 | FUT8 | 1340068 2340056 | 5180 | 0.065 | 0.0060 | No | ||
46 | DSCAM | 1780050 2450731 2810438 | 5251 | 0.062 | 0.0029 | No | ||
47 | KLHL13 | 6590731 | 5319 | 0.059 | -0.0001 | No | ||
48 | RAPGEF4 | 6100563 | 5405 | 0.056 | -0.0041 | No | ||
49 | NEGR1 | 1940731 5130170 | 5494 | 0.053 | -0.0084 | No | ||
50 | WTAP | 4010176 | 5624 | 0.048 | -0.0148 | No | ||
51 | ANKRD2 | 6590427 | 5776 | 0.043 | -0.0226 | No | ||
52 | PCDH15 | 7000438 | 5890 | 0.040 | -0.0283 | No | ||
53 | TCF2 | 870338 5050632 | 5933 | 0.039 | -0.0302 | No | ||
54 | GRIA1 | 1340152 3780750 4920440 | 5952 | 0.038 | -0.0307 | No | ||
55 | UNC13B | 130735 | 5955 | 0.038 | -0.0304 | No | ||
56 | MTSS1 | 780435 2370114 | 6048 | 0.035 | -0.0351 | No | ||
57 | MYH14 | 4010017 | 6049 | 0.035 | -0.0347 | No | ||
58 | GFAP | 2060092 | 6081 | 0.035 | -0.0360 | No | ||
59 | TREX2 | 4920707 | 6528 | 0.025 | -0.0599 | No | ||
60 | LAMA5 | 2680722 | 6538 | 0.024 | -0.0601 | No | ||
61 | NPEPPS | 2630731 | 6555 | 0.024 | -0.0608 | No | ||
62 | COL4A3 | 5910075 | 6599 | 0.023 | -0.0629 | No | ||
63 | NBL1 | 2480021 | 6726 | 0.020 | -0.0695 | No | ||
64 | HIF3A | 2630053 2680102 6450364 | 6848 | 0.018 | -0.0758 | No | ||
65 | AP1S2 | 780279 4280707 | 6958 | 0.016 | -0.0816 | No | ||
66 | SLC12A5 | 1980692 | 6959 | 0.016 | -0.0814 | No | ||
67 | NHLH1 | 6100452 | 7191 | 0.012 | -0.0938 | No | ||
68 | SORCS2 | 6350520 | 7239 | 0.011 | -0.0963 | No | ||
69 | FGF11 | 840292 | 7296 | 0.010 | -0.0992 | No | ||
70 | BMP6 | 2100128 | 7329 | 0.009 | -0.1008 | No | ||
71 | PTPRJ | 4010707 | 7634 | 0.004 | -0.1173 | No | ||
72 | CCNL2 | 6520167 | 7961 | -0.001 | -0.1349 | No | ||
73 | KCNB1 | 3610035 | 8065 | -0.003 | -0.1405 | No | ||
74 | PPARA | 2060026 | 8143 | -0.004 | -0.1446 | No | ||
75 | FOXI1 | 3710095 6620195 | 8376 | -0.008 | -0.1571 | No | ||
76 | CHRND | 840403 2260670 | 8517 | -0.010 | -0.1646 | No | ||
77 | MTUS1 | 780348 4920609 | 8643 | -0.012 | -0.1713 | No | ||
78 | ARVCF | 2190537 | 8662 | -0.013 | -0.1721 | No | ||
79 | SOST | 1170195 | 8799 | -0.015 | -0.1793 | No | ||
80 | SFTPC | 3290133 | 8897 | -0.016 | -0.1844 | No | ||
81 | ARHGEF12 | 3990195 | 9001 | -0.018 | -0.1898 | No | ||
82 | NFATC4 | 2470735 | 9158 | -0.021 | -0.1980 | No | ||
83 | GPM6B | 6220458 | 9490 | -0.027 | -0.2157 | No | ||
84 | GPR37 | 2320093 | 9511 | -0.027 | -0.2165 | No | ||
85 | CORO2B | 2340035 4850390 | 9539 | -0.027 | -0.2177 | No | ||
86 | DLL3 | 4010093 | 9542 | -0.027 | -0.2175 | No | ||
87 | GATA2 | 6590280 | 9668 | -0.029 | -0.2240 | No | ||
88 | DOC2A | 6020121 | 9781 | -0.032 | -0.2297 | No | ||
89 | ZNF205 | 6900022 | 9981 | -0.036 | -0.2401 | No | ||
90 | CPA4 | 3610100 | 10055 | -0.037 | -0.2437 | No | ||
91 | GDPD2 | 7000040 | 10236 | -0.041 | -0.2530 | No | ||
92 | CENTG3 | 2470079 4610092 5050170 | 10291 | -0.042 | -0.2555 | No | ||
93 | ALDH1A2 | 2320301 | 10391 | -0.044 | -0.2604 | No | ||
94 | RTN4RL2 | 6450609 | 10525 | -0.047 | -0.2671 | No | ||
95 | ODC1 | 5670168 | 10578 | -0.048 | -0.2694 | No | ||
96 | ROBO3 | 6550408 | 10668 | -0.051 | -0.2737 | No | ||
97 | PPP1R9B | 3130619 | 10678 | -0.051 | -0.2737 | No | ||
98 | CALN1 | 3610722 | 10720 | -0.052 | -0.2754 | No | ||
99 | NR4A1 | 6290161 | 10821 | -0.054 | -0.2802 | No | ||
100 | MYOZ3 | 1990138 | 10909 | -0.056 | -0.2843 | No | ||
101 | ANK2 | 6510546 | 10979 | -0.058 | -0.2875 | No | ||
102 | HSD11B2 | 5900053 | 10987 | -0.058 | -0.2872 | No | ||
103 | SLC24A3 | 5080707 | 11298 | -0.067 | -0.3033 | No | ||
104 | CPZ | 70193 | 11301 | -0.067 | -0.3027 | No | ||
105 | GJB2 | 5900609 6200487 | 11343 | -0.068 | -0.3042 | No | ||
106 | IRX6 | 4590025 | 11432 | -0.071 | -0.3083 | No | ||
107 | RASSF2 | 2480079 5720546 | 11794 | -0.083 | -0.3270 | No | ||
108 | MT3 | 1450537 | 11878 | -0.086 | -0.3306 | No | ||
109 | KCNK12 | 4070072 | 11886 | -0.086 | -0.3300 | No | ||
110 | CHST9 | 4560092 | 11963 | -0.089 | -0.3332 | No | ||
111 | CYP26A1 | 380022 2690600 | 12092 | -0.094 | -0.3391 | No | ||
112 | CALB1 | 460070 | 12290 | -0.103 | -0.3487 | No | ||
113 | POU2F3 | 2030601 | 12520 | -0.114 | -0.3600 | No | ||
114 | FSCN2 | 1230039 | 12543 | -0.115 | -0.3599 | No | ||
115 | TEAD4 | 1850239 6380519 | 12691 | -0.123 | -0.3666 | No | ||
116 | DLL1 | 1770377 | 12872 | -0.134 | -0.3749 | No | ||
117 | DNMT3A | 4050068 4810717 | 13051 | -0.146 | -0.3831 | No | ||
118 | CDH2 | 520435 2450451 2760025 6650477 | 13303 | -0.164 | -0.3949 | No | ||
119 | NOL4 | 5050446 5360519 | 13386 | -0.171 | -0.3976 | No | ||
120 | CANX | 4760402 | 13571 | -0.187 | -0.4056 | No | ||
121 | TNNC2 | 3840079 | 13653 | -0.195 | -0.4079 | No | ||
122 | PRKAG2 | 2340100 | 13904 | -0.220 | -0.4191 | No | ||
123 | PLCB3 | 4670402 | 13955 | -0.227 | -0.4195 | No | ||
124 | HOXB7 | 4540706 4610358 | 14055 | -0.237 | -0.4223 | No | ||
125 | GGN | 1410528 4210082 5290170 | 14150 | -0.249 | -0.4248 | No | ||
126 | FYN | 2100468 4760520 4850687 | 14227 | -0.260 | -0.4262 | No | ||
127 | MDGA1 | 1170139 | 14295 | -0.269 | -0.4270 | No | ||
128 | BRUNOL4 | 4490452 5080451 | 14324 | -0.272 | -0.4256 | No | ||
129 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 14365 | -0.276 | -0.4248 | No | ||
130 | DNAJB5 | 2900215 | 14367 | -0.277 | -0.4220 | No | ||
131 | PHACTR3 | 3850435 5900445 | 14402 | -0.282 | -0.4208 | No | ||
132 | LRP5 | 2100397 3170484 | 14478 | -0.295 | -0.4218 | No | ||
133 | SCG2 | 5670438 130671 | 14758 | -0.345 | -0.4333 | No | ||
134 | FGF8 | 6350504 | 14763 | -0.346 | -0.4298 | No | ||
135 | POFUT1 | 1570458 | 14826 | -0.354 | -0.4295 | No | ||
136 | USP2 | 1190292 1240253 4850035 | 14884 | -0.367 | -0.4287 | No | ||
137 | SEMA3F | 5420601 6770731 | 14908 | -0.372 | -0.4260 | No | ||
138 | SYT4 | 5080193 | 15259 | -0.448 | -0.4402 | No | ||
139 | ACTN3 | 3140541 6480598 | 15308 | -0.461 | -0.4380 | No | ||
140 | CXCL14 | 840114 6450324 | 15393 | -0.488 | -0.4374 | No | ||
141 | ITGB4 | 1740021 3840482 | 15586 | -0.552 | -0.4419 | Yes | ||
142 | TNFRSF21 | 6380100 | 15633 | -0.570 | -0.4384 | Yes | ||
143 | IGFBP5 | 2360592 | 15703 | -0.595 | -0.4359 | Yes | ||
144 | INVS | 4200632 6620528 | 15912 | -0.671 | -0.4401 | Yes | ||
145 | SIPA1 | 5220687 | 15944 | -0.687 | -0.4345 | Yes | ||
146 | CRELD1 | 2060253 | 16011 | -0.718 | -0.4305 | Yes | ||
147 | STC2 | 4920601 | 16076 | -0.749 | -0.4260 | Yes | ||
148 | DEF6 | 840593 | 16227 | -0.811 | -0.4256 | Yes | ||
149 | GRB7 | 2100471 | 16420 | -0.901 | -0.4265 | Yes | ||
150 | NEURL | 5390538 | 16543 | -0.962 | -0.4229 | Yes | ||
151 | ENO3 | 5270136 | 16556 | -0.967 | -0.4134 | Yes | ||
152 | CORO2A | 3840605 6620390 | 16575 | -0.976 | -0.4040 | Yes | ||
153 | POLR1D | 70082 450750 6040458 | 16599 | -0.990 | -0.3948 | Yes | ||
154 | ARHGAP24 | 540278 4540025 | 16626 | -0.996 | -0.3857 | Yes | ||
155 | RANGAP1 | 2320593 6650601 | 16802 | -1.071 | -0.3839 | Yes | ||
156 | IGSF8 | 1580592 | 16989 | -1.185 | -0.3814 | Yes | ||
157 | GPD1 | 2480095 | 17072 | -1.243 | -0.3728 | Yes | ||
158 | CENTB1 | 2120093 | 17228 | -1.343 | -0.3670 | Yes | ||
159 | CKM | 1450524 | 17235 | -1.346 | -0.3531 | Yes | ||
160 | TTC17 | 2470440 | 17281 | -1.376 | -0.3410 | Yes | ||
161 | IGF2 | 6510020 | 17345 | -1.422 | -0.3294 | Yes | ||
162 | ARID5A | 2450133 | 17395 | -1.460 | -0.3166 | Yes | ||
163 | PSTPIP1 | 3190156 | 17400 | -1.463 | -0.3014 | Yes | ||
164 | HES6 | 540411 6550504 | 17603 | -1.605 | -0.2953 | Yes | ||
165 | TNFSF13 | 2650170 | 17689 | -1.692 | -0.2821 | Yes | ||
166 | HMGA1 | 6580408 | 17829 | -1.825 | -0.2703 | Yes | ||
167 | SLC37A4 | 6400079 | 17914 | -1.909 | -0.2547 | Yes | ||
168 | SELL | 1190500 | 17943 | -1.940 | -0.2357 | Yes | ||
169 | GFRA1 | 3610152 | 18155 | -2.182 | -0.2241 | Yes | ||
170 | SASH1 | 4070270 | 18160 | -2.190 | -0.2012 | Yes | ||
171 | SMAD3 | 6450671 | 18195 | -2.238 | -0.1794 | Yes | ||
172 | PPOX | 2640678 3850102 | 18264 | -2.364 | -0.1581 | Yes | ||
173 | ELOVL1 | 2450019 4760138 5340685 | 18493 | -2.949 | -0.1393 | Yes | ||
174 | HEYL | 5860528 | 18552 | -3.298 | -0.1076 | Yes | ||
175 | AIG1 | 2450091 | 18558 | -3.339 | -0.0726 | Yes | ||
176 | PTK2B | 4730411 | 18576 | -3.507 | -0.0365 | Yes | ||
177 | GNAS | 630441 1850373 4050152 | 18584 | -3.653 | 0.0017 | Yes |