Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | wtNotch |
GeneSet | CAGTGTT,MIR-141,MIR-200A |
Enrichment Score (ES) | 0.6137201 |
Normalized Enrichment Score (NES) | 1.9796219 |
Nominal p-value | 0.0 |
FDR q-value | 9.528985E-4 |
FWER p-Value | 0.0010 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PITPNB | 5130039 | 45 | 3.342 | 0.0224 | Yes | ||
2 | PPP2CA | 3990113 | 47 | 3.290 | 0.0468 | Yes | ||
3 | WSB1 | 870563 | 49 | 3.256 | 0.0710 | Yes | ||
4 | TRAM1 | 2340441 6620592 | 51 | 3.221 | 0.0949 | Yes | ||
5 | SFPQ | 4760110 | 60 | 3.132 | 0.1178 | Yes | ||
6 | OGT | 2360131 4610333 | 109 | 2.829 | 0.1362 | Yes | ||
7 | SUPT6H | 3170082 | 121 | 2.797 | 0.1565 | Yes | ||
8 | ATP2A2 | 1090075 3990279 | 164 | 2.633 | 0.1738 | Yes | ||
9 | ANP32E | 6510706 | 166 | 2.630 | 0.1933 | Yes | ||
10 | APRIN | 2810050 | 224 | 2.494 | 0.2087 | Yes | ||
11 | RNF44 | 5910692 | 235 | 2.469 | 0.2266 | Yes | ||
12 | RABGAP1 | 5050397 | 236 | 2.466 | 0.2449 | Yes | ||
13 | PRKACB | 4210170 | 339 | 2.235 | 0.2560 | Yes | ||
14 | MTPN | 3940167 | 400 | 2.138 | 0.2686 | Yes | ||
15 | CUL3 | 1850520 | 446 | 2.066 | 0.2816 | Yes | ||
16 | DOLPP1 | 4780619 6400053 | 493 | 2.000 | 0.2940 | Yes | ||
17 | TULP4 | 2320364 | 549 | 1.905 | 0.3051 | Yes | ||
18 | RAP2C | 1690132 | 588 | 1.868 | 0.3170 | Yes | ||
19 | MAP2K4 | 5130133 | 595 | 1.863 | 0.3305 | Yes | ||
20 | BRD3 | 6130672 | 633 | 1.826 | 0.3421 | Yes | ||
21 | CD47 | 1850603 | 637 | 1.820 | 0.3555 | Yes | ||
22 | HOXB4 | 540131 | 766 | 1.681 | 0.3610 | Yes | ||
23 | CDV3 | 1940577 | 776 | 1.671 | 0.3730 | Yes | ||
24 | CSNK1G3 | 110450 | 809 | 1.640 | 0.3834 | Yes | ||
25 | H2AFZ | 1470168 | 822 | 1.628 | 0.3949 | Yes | ||
26 | MECP2 | 1940450 | 835 | 1.615 | 0.4063 | Yes | ||
27 | YWHAG | 3780341 | 868 | 1.581 | 0.4163 | Yes | ||
28 | ATP1B1 | 3130594 | 875 | 1.572 | 0.4276 | Yes | ||
29 | FKBP5 | 2190048 | 907 | 1.535 | 0.4374 | Yes | ||
30 | RUNX1 | 3840711 | 910 | 1.531 | 0.4487 | Yes | ||
31 | YTHDF2 | 4060332 4610279 | 926 | 1.501 | 0.4590 | Yes | ||
32 | OSBPL11 | 1770044 | 980 | 1.455 | 0.4670 | Yes | ||
33 | ANKFY1 | 360309 5390021 | 999 | 1.436 | 0.4767 | Yes | ||
34 | PLAGL2 | 1770148 | 1044 | 1.390 | 0.4846 | Yes | ||
35 | CCNE2 | 3120537 | 1049 | 1.388 | 0.4947 | Yes | ||
36 | SLC23A2 | 6660722 | 1054 | 1.380 | 0.5048 | Yes | ||
37 | SLC20A1 | 6420014 | 1099 | 1.332 | 0.5123 | Yes | ||
38 | ATP6V1A | 6590242 | 1103 | 1.330 | 0.5220 | Yes | ||
39 | ATP6V1B2 | 4060528 | 1116 | 1.319 | 0.5312 | Yes | ||
40 | MIB1 | 3800537 | 1217 | 1.228 | 0.5349 | Yes | ||
41 | SIRT1 | 1190731 | 1245 | 1.201 | 0.5424 | Yes | ||
42 | ARNTL | 3170463 | 1335 | 1.129 | 0.5459 | Yes | ||
43 | PDCD4 | 3360403 5690110 | 1356 | 1.111 | 0.5531 | Yes | ||
44 | DNAJC13 | 4730091 | 1391 | 1.082 | 0.5593 | Yes | ||
45 | TFRC | 4050551 | 1622 | 0.963 | 0.5540 | Yes | ||
46 | CDC14A | 4050132 | 1639 | 0.950 | 0.5602 | Yes | ||
47 | SIPA1L2 | 4850731 | 1664 | 0.930 | 0.5658 | Yes | ||
48 | RBMS1 | 6400014 | 1665 | 0.929 | 0.5727 | Yes | ||
49 | PPP1R15B | 2640280 5860082 | 1789 | 0.852 | 0.5723 | Yes | ||
50 | RTF1 | 2100735 | 1843 | 0.818 | 0.5756 | Yes | ||
51 | YAF2 | 940053 | 1855 | 0.810 | 0.5810 | Yes | ||
52 | STAT4 | 1660373 3130019 | 1891 | 0.792 | 0.5850 | Yes | ||
53 | ARHGEF18 | 2120279 | 1903 | 0.785 | 0.5902 | Yes | ||
54 | KIF3A | 5050348 6650079 | 1941 | 0.763 | 0.5939 | Yes | ||
55 | MBNL1 | 2640762 7100048 | 2031 | 0.700 | 0.5943 | Yes | ||
56 | GRB2 | 6650398 | 2049 | 0.690 | 0.5985 | Yes | ||
57 | WDR44 | 130195 1050609 1570685 | 2204 | 0.621 | 0.5947 | Yes | ||
58 | CDC25A | 3800184 | 2212 | 0.617 | 0.5989 | Yes | ||
59 | MYH10 | 2640673 | 2217 | 0.614 | 0.6033 | Yes | ||
60 | TCF12 | 3610324 7000156 | 2233 | 0.608 | 0.6070 | Yes | ||
61 | FOXP1 | 6510433 | 2240 | 0.605 | 0.6112 | Yes | ||
62 | BACE1 | 2650438 | 2275 | 0.592 | 0.6137 | Yes | ||
63 | UBE3A | 1240152 2690438 5860609 | 2634 | 0.461 | 0.5977 | No | ||
64 | SLC25A3 | 670112 | 2660 | 0.455 | 0.5997 | No | ||
65 | MOBKL2B | 940128 | 2667 | 0.452 | 0.6027 | No | ||
66 | FUS | 4760619 | 2740 | 0.426 | 0.6020 | No | ||
67 | YTHDF3 | 4540632 4670717 7040609 | 2760 | 0.421 | 0.6041 | No | ||
68 | AK3L1 | 7100601 | 2922 | 0.367 | 0.5981 | No | ||
69 | MARCH7 | 3800020 6620168 | 2984 | 0.347 | 0.5973 | No | ||
70 | PTGES3 | 2190440 2680524 | 3058 | 0.323 | 0.5958 | No | ||
71 | SPAG9 | 580497 2510180 4210685 | 3071 | 0.321 | 0.5975 | No | ||
72 | BICD2 | 1090411 | 3127 | 0.306 | 0.5968 | No | ||
73 | SLC6A9 | 2470520 | 3203 | 0.287 | 0.5948 | No | ||
74 | CHD9 | 430037 2570129 5420398 | 3253 | 0.277 | 0.5942 | No | ||
75 | FBXL2 | 6450722 | 3268 | 0.273 | 0.5955 | No | ||
76 | CALU | 2680403 3520056 4610348 5720176 6130121 | 3370 | 0.251 | 0.5919 | No | ||
77 | GATA6 | 1770010 | 3437 | 0.236 | 0.5901 | No | ||
78 | TNS3 | 6380242 | 3533 | 0.216 | 0.5865 | No | ||
79 | CBL | 6380068 | 3569 | 0.209 | 0.5861 | No | ||
80 | TTR | 4150072 | 3589 | 0.206 | 0.5866 | No | ||
81 | SLC39A9 | 3940348 | 3682 | 0.192 | 0.5831 | No | ||
82 | ATF5 | 5670685 | 3759 | 0.180 | 0.5803 | No | ||
83 | OLIG3 | 1050603 | 3822 | 0.171 | 0.5782 | No | ||
84 | PBEF1 | 1090278 | 3842 | 0.168 | 0.5784 | No | ||
85 | BAP1 | 3830131 | 3845 | 0.168 | 0.5795 | No | ||
86 | SEPT7 | 2760685 | 3911 | 0.158 | 0.5772 | No | ||
87 | QKI | 5220093 6130044 | 4072 | 0.139 | 0.5695 | No | ||
88 | DDX5 | 940021 2630338 3440148 | 4090 | 0.137 | 0.5696 | No | ||
89 | KPNA3 | 7040088 | 4093 | 0.137 | 0.5705 | No | ||
90 | THRAP2 | 4920600 | 4133 | 0.134 | 0.5694 | No | ||
91 | HMG20A | 4590113 | 4268 | 0.122 | 0.5630 | No | ||
92 | OLFM1 | 3360161 5570066 | 4318 | 0.117 | 0.5612 | No | ||
93 | NFASC | 1940619 2470156 4590168 6840524 | 4328 | 0.116 | 0.5616 | No | ||
94 | CSNK2A1 | 1580577 | 4329 | 0.116 | 0.5625 | No | ||
95 | PHLPP | 3440563 | 4359 | 0.114 | 0.5617 | No | ||
96 | STXBP1 | 360072 6220717 | 4489 | 0.103 | 0.5555 | No | ||
97 | NRXN1 | 460408 5340270 6370066 | 4506 | 0.101 | 0.5554 | No | ||
98 | PCTK2 | 5700673 | 4590 | 0.096 | 0.5516 | No | ||
99 | RPH3AL | 70110 | 4593 | 0.096 | 0.5522 | No | ||
100 | KCNJ2 | 630019 | 4630 | 0.094 | 0.5509 | No | ||
101 | RTN4RL1 | 2630368 | 4697 | 0.089 | 0.5480 | No | ||
102 | E2F3 | 50162 460180 | 4748 | 0.086 | 0.5459 | No | ||
103 | TIAL1 | 4150048 6510605 | 4813 | 0.082 | 0.5430 | No | ||
104 | RAD23B | 2190671 | 4822 | 0.082 | 0.5432 | No | ||
105 | HIPK1 | 110193 | 4934 | 0.076 | 0.5377 | No | ||
106 | FGFR2 | 4670601 5570402 6940377 | 5095 | 0.069 | 0.5295 | No | ||
107 | TCERG1 | 2350551 4540397 5220746 | 5343 | 0.059 | 0.5165 | No | ||
108 | ARPC5 | 1740411 3450300 | 5348 | 0.058 | 0.5168 | No | ||
109 | EXOC5 | 7000711 | 5425 | 0.055 | 0.5130 | No | ||
110 | PTP4A1 | 130692 | 5455 | 0.054 | 0.5119 | No | ||
111 | TSC1 | 1850672 | 5592 | 0.049 | 0.5048 | No | ||
112 | HOXC13 | 4070722 | 5881 | 0.040 | 0.4895 | No | ||
113 | SOX11 | 610279 | 5948 | 0.038 | 0.4862 | No | ||
114 | RARB | 430139 1410138 | 6002 | 0.037 | 0.4836 | No | ||
115 | MTSS1 | 780435 2370114 | 6048 | 0.035 | 0.4814 | No | ||
116 | MYRIP | 1580471 | 6133 | 0.033 | 0.4771 | No | ||
117 | THRB | 1780673 | 6237 | 0.031 | 0.4717 | No | ||
118 | SRC | 580132 | 6242 | 0.031 | 0.4717 | No | ||
119 | NRP2 | 4070400 5860041 6650446 | 6307 | 0.030 | 0.4685 | No | ||
120 | SNAP91 | 3170056 5690520 | 6406 | 0.027 | 0.4633 | No | ||
121 | PHYHIPL | 2360706 3840692 | 6539 | 0.024 | 0.4563 | No | ||
122 | CXCL12 | 580546 4150750 4570068 | 6718 | 0.020 | 0.4468 | No | ||
123 | ATXN7 | 1450435 | 6863 | 0.018 | 0.4391 | No | ||
124 | PLAG1 | 1450142 3870139 6520039 | 6905 | 0.017 | 0.4370 | No | ||
125 | DR1 | 5860750 | 6911 | 0.017 | 0.4369 | No | ||
126 | TRHDE | 1690068 | 7132 | 0.012 | 0.4250 | No | ||
127 | CLASP2 | 2510139 | 7204 | 0.011 | 0.4212 | No | ||
128 | DUSP3 | 1240129 6840215 | 7219 | 0.011 | 0.4205 | No | ||
129 | MMP16 | 2680139 | 7379 | 0.009 | 0.4119 | No | ||
130 | PITX2 | 870537 2690139 | 7394 | 0.008 | 0.4112 | No | ||
131 | KHDRBS2 | 3520717 | 7537 | 0.006 | 0.4036 | No | ||
132 | MYT1L | 5670369 6660403 | 7567 | 0.005 | 0.4020 | No | ||
133 | SLC16A7 | 2320672 | 7609 | 0.005 | 0.3998 | No | ||
134 | SLC1A1 | 520372 6420059 | 7650 | 0.004 | 0.3977 | No | ||
135 | HNRPF | 670138 | 7677 | 0.004 | 0.3963 | No | ||
136 | PCDH8 | 2360047 4200452 | 8099 | -0.003 | 0.3734 | No | ||
137 | NR2C2 | 6100097 | 8223 | -0.005 | 0.3668 | No | ||
138 | SPG3A | 2760091 3120170 | 8340 | -0.007 | 0.3605 | No | ||
139 | PAFAH1B2 | 5360546 6860672 | 8398 | -0.008 | 0.3575 | No | ||
140 | SP4 | 3850176 | 8553 | -0.011 | 0.3492 | No | ||
141 | DIXDC1 | 6980435 | 8569 | -0.011 | 0.3485 | No | ||
142 | LENG8 | 3130731 | 8607 | -0.012 | 0.3466 | No | ||
143 | ESRRG | 4010181 | 8690 | -0.013 | 0.3422 | No | ||
144 | ITSN1 | 2640577 | 9091 | -0.020 | 0.3206 | No | ||
145 | ZCCHC3 | 580438 1990035 4780278 | 9206 | -0.022 | 0.3146 | No | ||
146 | CHES1 | 4570121 5700162 | 9269 | -0.023 | 0.3114 | No | ||
147 | STK35 | 2360121 | 9307 | -0.024 | 0.3095 | No | ||
148 | GRIN3A | 2370592 | 9420 | -0.025 | 0.3036 | No | ||
149 | ACVR2A | 6110647 | 9468 | -0.026 | 0.3013 | No | ||
150 | GPM6B | 6220458 | 9490 | -0.027 | 0.3003 | No | ||
151 | ZFR | 5910647 | 9524 | -0.027 | 0.2987 | No | ||
152 | CSNK1A1 | 2340427 | 9676 | -0.030 | 0.2907 | No | ||
153 | EPHA7 | 1190288 4010278 | 9713 | -0.030 | 0.2890 | No | ||
154 | HOXA11 | 6980133 | 9753 | -0.031 | 0.2871 | No | ||
155 | LHX6 | 2360731 3360397 | 9966 | -0.036 | 0.2758 | No | ||
156 | WDFY3 | 3610041 4560333 4570273 | 9973 | -0.036 | 0.2758 | No | ||
157 | RBM7 | 5890348 | 9987 | -0.036 | 0.2753 | No | ||
158 | PCDH9 | 2100136 | 10225 | -0.040 | 0.2628 | No | ||
159 | LPP | 1660541 | 10461 | -0.046 | 0.2503 | No | ||
160 | B3GNT1 | 2350446 | 10467 | -0.046 | 0.2504 | No | ||
161 | SNF1LK | 6110403 | 10563 | -0.048 | 0.2456 | No | ||
162 | HLF | 2370113 | 10626 | -0.050 | 0.2426 | No | ||
163 | APBB2 | 5130403 | 10683 | -0.051 | 0.2399 | No | ||
164 | CALCR | 1690494 | 10808 | -0.054 | 0.2336 | No | ||
165 | TMEFF1 | 2680100 | 10854 | -0.055 | 0.2315 | No | ||
166 | FOXA1 | 3710609 | 10883 | -0.056 | 0.2304 | No | ||
167 | WDR26 | 1090138 | 10910 | -0.056 | 0.2294 | No | ||
168 | LYPLA1 | 4480373 5570551 | 10923 | -0.056 | 0.2292 | No | ||
169 | SEMA6A | 2690138 3060021 | 11083 | -0.061 | 0.2210 | No | ||
170 | DRD2 | 5890369 | 11100 | -0.061 | 0.2206 | No | ||
171 | TTYH2 | 1450397 3870100 6550347 | 11111 | -0.062 | 0.2205 | No | ||
172 | SLC17A6 | 4210576 | 11731 | -0.080 | 0.1875 | No | ||
173 | TM9SF4 | 450538 1050093 4210112 | 11768 | -0.082 | 0.1861 | No | ||
174 | TGFB2 | 4920292 | 11864 | -0.085 | 0.1816 | No | ||
175 | CNR1 | 6550494 6760497 | 11978 | -0.090 | 0.1761 | No | ||
176 | PTPRG | 2650524 1340022 | 11983 | -0.090 | 0.1766 | No | ||
177 | BRUNOL6 | 6840373 | 12121 | -0.096 | 0.1698 | No | ||
178 | HOXB5 | 2900538 | 12257 | -0.101 | 0.1632 | No | ||
179 | ELF2 | 1690014 2480132 3060180 3190504 | 12261 | -0.101 | 0.1638 | No | ||
180 | POU4F1 | 2260315 | 12389 | -0.108 | 0.1577 | No | ||
181 | CNP | 2260451 | 12407 | -0.108 | 0.1576 | No | ||
182 | JUN | 840170 | 12506 | -0.114 | 0.1531 | No | ||
183 | PPT2 | 2340059 3450148 | 12510 | -0.114 | 0.1538 | No | ||
184 | PPP2R2A | 2900014 5700575 | 12541 | -0.115 | 0.1530 | No | ||
185 | USP9X | 130435 2370735 3120338 | 12708 | -0.124 | 0.1449 | No | ||
186 | ELAVL2 | 360181 | 12761 | -0.127 | 0.1430 | No | ||
187 | CPD | 5360403 5860685 | 12814 | -0.130 | 0.1412 | No | ||
188 | LRRC8A | 2510193 | 12889 | -0.135 | 0.1382 | No | ||
189 | KLHL18 | 4560075 | 12916 | -0.137 | 0.1378 | No | ||
190 | STRN | 5570706 7050333 | 13039 | -0.145 | 0.1322 | No | ||
191 | STAT5B | 6200026 | 13123 | -0.151 | 0.1288 | No | ||
192 | EPHA2 | 5890056 | 13204 | -0.156 | 0.1256 | No | ||
193 | RAB38 | 2970735 | 13428 | -0.174 | 0.1148 | No | ||
194 | SIM2 | 2100044 | 13488 | -0.180 | 0.1129 | No | ||
195 | CSF3 | 2230193 6660707 | 13498 | -0.181 | 0.1138 | No | ||
196 | GPC2 | 130647 | 13584 | -0.188 | 0.1106 | No | ||
197 | CYP26B1 | 2630142 | 13618 | -0.192 | 0.1102 | No | ||
198 | PAPPA | 4230463 | 13720 | -0.202 | 0.1062 | No | ||
199 | ACACA | 2490612 2680369 | 13949 | -0.226 | 0.0955 | No | ||
200 | SOX5 | 2370576 2900167 3190128 5050528 | 14287 | -0.268 | 0.0792 | No | ||
201 | MDGA1 | 1170139 | 14295 | -0.269 | 0.0808 | No | ||
202 | KIF1C | 2480484 | 14632 | -0.323 | 0.0649 | No | ||
203 | ATXN1 | 5550156 | 15042 | -0.402 | 0.0457 | No | ||
204 | PEX5 | 1240746 1570092 2510487 | 15064 | -0.406 | 0.0476 | No | ||
205 | SPRYD3 | 50403 | 15086 | -0.411 | 0.0495 | No | ||
206 | SYT4 | 5080193 | 15259 | -0.448 | 0.0435 | No | ||
207 | DLC1 | 1090632 6450594 | 15517 | -0.529 | 0.0334 | No | ||
208 | TAF12 | 3710746 4920300 6180603 | 15574 | -0.547 | 0.0345 | No | ||
209 | MDM1 | 510528 1780280 2680152 2690181 3060025 3120487 4210601 4540037 4610142 5290110 6400433 6480743 | 15631 | -0.570 | 0.0357 | No | ||
210 | FRMD4A | 2190176 | 15853 | -0.644 | 0.0284 | No | ||
211 | DEK | 1050451 4560037 | 16016 | -0.722 | 0.0250 | No | ||
212 | AMPD2 | 630093 1170070 | 16126 | -0.769 | 0.0248 | No | ||
213 | STAT5A | 2680458 | 16269 | -0.833 | 0.0233 | No | ||
214 | SERF2 | 5720010 | 16283 | -0.840 | 0.0288 | No | ||
215 | PSEN1 | 130403 2030647 6100603 | 16421 | -0.902 | 0.0281 | No | ||
216 | HIC2 | 4010433 | 16466 | -0.923 | 0.0325 | No | ||
217 | SON | 3120148 5860239 7040403 | 16514 | -0.945 | 0.0370 | No | ||
218 | TOP1 | 770471 4060632 6650324 | 16558 | -0.968 | 0.0419 | No | ||
219 | DMWD | 770019 1690047 | 16694 | -1.019 | 0.0421 | No | ||
220 | HRBL | 1850102 3830253 4780176 | 16808 | -1.075 | 0.0440 | No | ||
221 | EPN1 | 4060725 | 17026 | -1.211 | 0.0412 | No | ||
222 | ACOT7 | 730735 1400176 7050053 | 17154 | -1.298 | 0.0440 | No | ||
223 | BHLHB2 | 7040603 | 17399 | -1.463 | 0.0416 | No | ||
224 | ST3GAL3 | 2810601 | 17561 | -1.570 | 0.0445 | No | ||
225 | CDC42BPB | 6350037 | 17725 | -1.721 | 0.0484 | No |