Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | wtNotch |
GeneSet | ATGTACA,MIR-493 |
Enrichment Score (ES) | 0.5780098 |
Normalized Enrichment Score (NES) | 1.8604954 |
Nominal p-value | 0.0 |
FDR q-value | 0.0022623104 |
FWER p-Value | 0.0080 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | MCL1 | 1660672 | 6 | 4.296 | 0.0311 | Yes | ||
2 | BRD7 | 2120068 6200746 | 12 | 3.947 | 0.0598 | Yes | ||
3 | UBE2G1 | 2230546 5420528 7040463 | 61 | 3.099 | 0.0799 | Yes | ||
4 | ARID1A | 2630022 1690551 4810110 | 78 | 2.995 | 0.1010 | Yes | ||
5 | APLP2 | 3610037 | 88 | 2.931 | 0.1219 | Yes | ||
6 | RHOT1 | 6760692 | 112 | 2.826 | 0.1414 | Yes | ||
7 | AP3S1 | 5570044 | 132 | 2.755 | 0.1605 | Yes | ||
8 | CLPX | 6220156 | 154 | 2.674 | 0.1790 | Yes | ||
9 | ATP2A2 | 1090075 3990279 | 164 | 2.633 | 0.1978 | Yes | ||
10 | HMGCS1 | 6620452 | 169 | 2.621 | 0.2168 | Yes | ||
11 | SIN3A | 2190121 | 191 | 2.561 | 0.2344 | Yes | ||
12 | SFRS3 | 770315 4230593 | 276 | 2.375 | 0.2472 | Yes | ||
13 | PPP3CB | 6020156 | 277 | 2.375 | 0.2646 | Yes | ||
14 | NMT1 | 5810152 | 280 | 2.373 | 0.2819 | Yes | ||
15 | TBK1 | 5690338 | 348 | 2.222 | 0.2945 | Yes | ||
16 | MTPN | 3940167 | 400 | 2.138 | 0.3074 | Yes | ||
17 | CTDSPL | 4670546 | 433 | 2.083 | 0.3209 | Yes | ||
18 | MBNL2 | 3450707 | 439 | 2.076 | 0.3359 | Yes | ||
19 | ETF1 | 6770075 | 480 | 2.016 | 0.3485 | Yes | ||
20 | NCOA1 | 3610438 | 543 | 1.911 | 0.3591 | Yes | ||
21 | DHX36 | 2470465 | 550 | 1.905 | 0.3727 | Yes | ||
22 | SRPK2 | 6380341 | 580 | 1.872 | 0.3849 | Yes | ||
23 | PIAS1 | 5340301 | 607 | 1.854 | 0.3970 | Yes | ||
24 | ZFX | 5900400 | 704 | 1.744 | 0.4046 | Yes | ||
25 | ITSN2 | 780484 | 770 | 1.677 | 0.4133 | Yes | ||
26 | KLF3 | 5130438 | 782 | 1.666 | 0.4249 | Yes | ||
27 | PAIP1 | 3870576 | 825 | 1.625 | 0.4346 | Yes | ||
28 | IRF2 | 5390044 | 888 | 1.557 | 0.4426 | Yes | ||
29 | DDX3X | 2190020 | 949 | 1.484 | 0.4502 | Yes | ||
30 | EIF4ENIF1 | 2060341 | 1130 | 1.305 | 0.4500 | Yes | ||
31 | BCL7A | 4560095 | 1148 | 1.282 | 0.4584 | Yes | ||
32 | KBTBD2 | 2320014 | 1175 | 1.261 | 0.4663 | Yes | ||
33 | CDC73 | 1580132 | 1227 | 1.222 | 0.4724 | Yes | ||
34 | TTC7B | 4760725 | 1258 | 1.193 | 0.4796 | Yes | ||
35 | PHF2 | 4060300 | 1263 | 1.188 | 0.4880 | Yes | ||
36 | FMNL2 | 4060438 | 1330 | 1.131 | 0.4927 | Yes | ||
37 | CREBBP | 5690035 7040050 | 1378 | 1.091 | 0.4982 | Yes | ||
38 | DNAJC13 | 4730091 | 1391 | 1.082 | 0.5054 | Yes | ||
39 | EFTUD1 | 5360736 | 1425 | 1.054 | 0.5114 | Yes | ||
40 | PDPK1 | 6650168 | 1530 | 1.001 | 0.5131 | Yes | ||
41 | BTG1 | 4200735 6040131 6200133 | 1533 | 1.000 | 0.5203 | Yes | ||
42 | PPP2R5D | 4010156 380408 5550112 5670162 | 1582 | 0.982 | 0.5249 | Yes | ||
43 | DCUN1D1 | 2360332 | 1609 | 0.972 | 0.5306 | Yes | ||
44 | CDC14A | 4050132 | 1639 | 0.950 | 0.5359 | Yes | ||
45 | SIPA1L2 | 4850731 | 1664 | 0.930 | 0.5415 | Yes | ||
46 | RYBP | 60746 | 1721 | 0.894 | 0.5450 | Yes | ||
47 | NUDT4 | 6760689 | 1775 | 0.860 | 0.5484 | Yes | ||
48 | UTX | 2900017 6770452 | 1857 | 0.810 | 0.5499 | Yes | ||
49 | ITGB1 | 5080156 6270528 | 1877 | 0.801 | 0.5547 | Yes | ||
50 | MLLT10 | 1410288 3290142 | 1986 | 0.735 | 0.5543 | Yes | ||
51 | PPP1R10 | 110136 3170725 3610484 | 2113 | 0.666 | 0.5523 | Yes | ||
52 | FBXO33 | 1510504 | 2117 | 0.664 | 0.5570 | Yes | ||
53 | RBBP6 | 2320129 | 2142 | 0.650 | 0.5604 | Yes | ||
54 | MADD | 6100725 7000088 | 2162 | 0.638 | 0.5641 | Yes | ||
55 | ARFGEF1 | 6760494 | 2271 | 0.593 | 0.5626 | Yes | ||
56 | CUGBP2 | 6180121 6840139 | 2277 | 0.592 | 0.5666 | Yes | ||
57 | SVIL | 2450347 4050735 4070576 4120706 5390161 5860142 6520278 7100397 | 2335 | 0.569 | 0.5677 | Yes | ||
58 | XPO7 | 2630215 6760014 | 2355 | 0.560 | 0.5708 | Yes | ||
59 | DAB2IP | 3170064 6200441 | 2367 | 0.555 | 0.5742 | Yes | ||
60 | FOXO1A | 3120670 | 2373 | 0.553 | 0.5780 | Yes | ||
61 | MAPK1 | 3190193 6200253 | 2520 | 0.498 | 0.5737 | No | ||
62 | UBE3A | 1240152 2690438 5860609 | 2634 | 0.461 | 0.5710 | No | ||
63 | GNB1 | 2120397 | 2641 | 0.459 | 0.5740 | No | ||
64 | PDE4D | 2470528 6660014 | 2699 | 0.441 | 0.5741 | No | ||
65 | ANKRD17 | 2120402 3850035 6400044 | 2802 | 0.408 | 0.5716 | No | ||
66 | AR | 6380167 | 3059 | 0.323 | 0.5600 | No | ||
67 | RPS6KA5 | 2120563 7040546 | 3063 | 0.322 | 0.5622 | No | ||
68 | PHF12 | 870400 3130687 | 3125 | 0.306 | 0.5611 | No | ||
69 | AXIN1 | 3360358 6940451 | 3148 | 0.299 | 0.5621 | No | ||
70 | GTF2IRD1 | 2030154 3990040 5080372 | 3200 | 0.287 | 0.5615 | No | ||
71 | SH2D3C | 3060014 | 3205 | 0.286 | 0.5633 | No | ||
72 | SPIRE2 | 450088 | 3374 | 0.251 | 0.5560 | No | ||
73 | CARM1 | 7040292 | 3428 | 0.239 | 0.5549 | No | ||
74 | FBS1 | 2570520 | 3463 | 0.231 | 0.5548 | No | ||
75 | BAZ2A | 730184 | 3493 | 0.226 | 0.5548 | No | ||
76 | RALGPS1 | 3440129 6400746 | 3495 | 0.226 | 0.5564 | No | ||
77 | CLASP1 | 6860279 | 3529 | 0.218 | 0.5562 | No | ||
78 | HEMGN | 670411 | 3620 | 0.202 | 0.5528 | No | ||
79 | TLE4 | 1450064 1500519 | 3753 | 0.181 | 0.5470 | No | ||
80 | RBM12 | 4570239 6040411 6660129 | 3764 | 0.179 | 0.5477 | No | ||
81 | JARID1B | 4730494 | 3815 | 0.172 | 0.5463 | No | ||
82 | EIF2C1 | 6900551 | 3843 | 0.168 | 0.5460 | No | ||
83 | SSH2 | 360056 | 4039 | 0.142 | 0.5365 | No | ||
84 | THRAP2 | 4920600 | 4133 | 0.134 | 0.5324 | No | ||
85 | NAB1 | 430739 1230114 3390736 6660056 | 4160 | 0.130 | 0.5320 | No | ||
86 | E2F6 | 3120133 3850332 4070324 | 4267 | 0.122 | 0.5271 | No | ||
87 | CCNT2 | 2100390 4150563 | 4381 | 0.111 | 0.5218 | No | ||
88 | SPRED2 | 510138 540195 | 4390 | 0.111 | 0.5221 | No | ||
89 | PCGF2 | 6370347 | 4445 | 0.106 | 0.5200 | No | ||
90 | TJP1 | 6350184 | 4509 | 0.101 | 0.5173 | No | ||
91 | SORCS3 | 5700309 | 4624 | 0.094 | 0.5118 | No | ||
92 | KIF1B | 1240494 2370139 4570270 6510102 | 4651 | 0.092 | 0.5110 | No | ||
93 | RSBN1 | 7000487 | 4665 | 0.091 | 0.5110 | No | ||
94 | PBX3 | 1300424 3710577 6180575 | 4737 | 0.086 | 0.5078 | No | ||
95 | PIP5K3 | 5360112 | 4825 | 0.082 | 0.5036 | No | ||
96 | WNT5A | 840685 3120152 | 4829 | 0.081 | 0.5041 | No | ||
97 | HIPK1 | 110193 | 4934 | 0.076 | 0.4990 | No | ||
98 | SEMA4C | 1980315 | 5211 | 0.063 | 0.4844 | No | ||
99 | PFN2 | 730040 5700026 | 5291 | 0.060 | 0.4806 | No | ||
100 | DUSP16 | 2370082 2480450 | 5424 | 0.055 | 0.4738 | No | ||
101 | SPEN | 2060041 | 5991 | 0.037 | 0.4433 | No | ||
102 | OSBPL6 | 3800072 | 6040 | 0.036 | 0.4410 | No | ||
103 | GPC4 | 5910408 | 6054 | 0.035 | 0.4405 | No | ||
104 | TNFSF11 | 6350204 | 6068 | 0.035 | 0.4401 | No | ||
105 | THRAP1 | 2470121 | 6434 | 0.027 | 0.4204 | No | ||
106 | GABRA5 | 5570215 | 6579 | 0.023 | 0.4128 | No | ||
107 | KCNIP4 | 4120435 7050605 | 6659 | 0.022 | 0.4086 | No | ||
108 | ZIC2 | 1410408 | 6667 | 0.021 | 0.4084 | No | ||
109 | GABRA1 | 130372 | 6704 | 0.021 | 0.4066 | No | ||
110 | SALL1 | 5420020 7050195 | 6955 | 0.016 | 0.3931 | No | ||
111 | PUM2 | 4200441 5910446 | 7013 | 0.015 | 0.3901 | No | ||
112 | UNC50 | 4920037 | 7068 | 0.014 | 0.3873 | No | ||
113 | BHLHB5 | 6510520 | 7259 | 0.010 | 0.3771 | No | ||
114 | NLGN1 | 5670278 | 7325 | 0.009 | 0.3736 | No | ||
115 | NLGN3 | 2650463 | 7375 | 0.009 | 0.3710 | No | ||
116 | DACH1 | 2450593 5700592 | 7395 | 0.008 | 0.3700 | No | ||
117 | KCNMA1 | 1450402 | 7396 | 0.008 | 0.3701 | No | ||
118 | PCDH18 | 430010 | 7418 | 0.008 | 0.3690 | No | ||
119 | SS18 | 1940440 2900072 6900129 | 7497 | 0.007 | 0.3648 | No | ||
120 | SP3 | 3840338 | 7643 | 0.004 | 0.3570 | No | ||
121 | NDST1 | 1500427 5340121 | 7881 | 0.000 | 0.3441 | No | ||
122 | RPE | 940114 | 8296 | -0.006 | 0.3216 | No | ||
123 | ADAM10 | 3780156 | 8396 | -0.008 | 0.3163 | No | ||
124 | SP4 | 3850176 | 8553 | -0.011 | 0.3079 | No | ||
125 | ZIC1 | 670113 | 8581 | -0.011 | 0.3065 | No | ||
126 | BHLHB3 | 3450438 | 8625 | -0.012 | 0.3043 | No | ||
127 | ARHGAP5 | 2510619 3360035 | 8655 | -0.013 | 0.3028 | No | ||
128 | ESRRG | 4010181 | 8690 | -0.013 | 0.3010 | No | ||
129 | PDZRN3 | 2340131 | 8958 | -0.018 | 0.2866 | No | ||
130 | SERTAD2 | 2810673 6840450 | 9012 | -0.019 | 0.2839 | No | ||
131 | SNX9 | 3290592 | 9026 | -0.019 | 0.2833 | No | ||
132 | PIK3R1 | 4730671 | 9205 | -0.022 | 0.2738 | No | ||
133 | EYA1 | 1450278 5220390 | 9227 | -0.022 | 0.2728 | No | ||
134 | RIMS3 | 3890563 | 9388 | -0.025 | 0.2643 | No | ||
135 | CPNE8 | 7040039 | 9465 | -0.026 | 0.2604 | No | ||
136 | DKK2 | 3610433 | 9600 | -0.028 | 0.2533 | No | ||
137 | CRSP6 | 2940358 | 9663 | -0.029 | 0.2501 | No | ||
138 | CSNK1A1 | 2340427 | 9676 | -0.030 | 0.2497 | No | ||
139 | EPHA7 | 1190288 4010278 | 9713 | -0.030 | 0.2480 | No | ||
140 | WDFY3 | 3610041 4560333 4570273 | 9973 | -0.036 | 0.2341 | No | ||
141 | FIGN | 7000601 | 10027 | -0.037 | 0.2315 | No | ||
142 | BCOR | 1660452 3940053 | 10054 | -0.037 | 0.2304 | No | ||
143 | PSD2 | 2060091 | 10120 | -0.038 | 0.2271 | No | ||
144 | TTN | 2320161 4670056 6550026 | 10145 | -0.039 | 0.2261 | No | ||
145 | SRPX | 580717 1980162 | 10220 | -0.040 | 0.2224 | No | ||
146 | NRXN3 | 1400546 3360471 | 10243 | -0.041 | 0.2215 | No | ||
147 | LRRTM3 | 4210021 | 10308 | -0.042 | 0.2183 | No | ||
148 | BASP1 | 5700044 | 10406 | -0.045 | 0.2134 | No | ||
149 | IRX3 | 4200112 | 10657 | -0.050 | 0.2002 | No | ||
150 | ENAH | 1690292 5700300 | 10747 | -0.052 | 0.1957 | No | ||
151 | SV2B | 3850717 | 10813 | -0.054 | 0.1926 | No | ||
152 | TMEFF1 | 2680100 | 10854 | -0.055 | 0.1908 | No | ||
153 | CDH11 | 1230133 2100180 4610110 | 11003 | -0.059 | 0.1832 | No | ||
154 | CAPN3 | 1980451 6940047 | 11291 | -0.067 | 0.1681 | No | ||
155 | ZBTB11 | 6520092 | 11299 | -0.067 | 0.1682 | No | ||
156 | MEF2C | 670025 780338 | 11302 | -0.067 | 0.1686 | No | ||
157 | FHOD3 | 1240541 | 11423 | -0.071 | 0.1626 | No | ||
158 | PTPN12 | 2030309 6020725 6130746 6290609 | 11427 | -0.071 | 0.1629 | No | ||
159 | GAB1 | 2970156 | 11513 | -0.073 | 0.1588 | No | ||
160 | FZD4 | 1580520 | 11709 | -0.079 | 0.1488 | No | ||
161 | UBE2V2 | 4210484 | 11909 | -0.087 | 0.1386 | No | ||
162 | CUL5 | 450142 | 12089 | -0.094 | 0.1296 | No | ||
163 | GRM5 | 60528 | 12137 | -0.096 | 0.1277 | No | ||
164 | HS3ST3B1 | 380040 | 12146 | -0.096 | 0.1280 | No | ||
165 | COBLL1 | 4230056 6370494 | 12216 | -0.099 | 0.1250 | No | ||
166 | POU4F1 | 2260315 | 12389 | -0.108 | 0.1164 | No | ||
167 | JUN | 840170 | 12506 | -0.114 | 0.1109 | No | ||
168 | NXPH1 | 3870546 | 12561 | -0.116 | 0.1089 | No | ||
169 | IL1A | 3610056 | 12568 | -0.117 | 0.1094 | No | ||
170 | AK5 | 6290348 | 12609 | -0.119 | 0.1081 | No | ||
171 | MARK1 | 450484 | 12657 | -0.121 | 0.1064 | No | ||
172 | PDGFC | 4200133 | 12787 | -0.129 | 0.1004 | No | ||
173 | SOX21 | 1050110 4670041 6660338 | 12869 | -0.134 | 0.0969 | No | ||
174 | DLL1 | 1770377 | 12872 | -0.134 | 0.0978 | No | ||
175 | TRAM2 | 3940112 | 12971 | -0.140 | 0.0935 | No | ||
176 | CDH13 | 5130368 5340114 | 13102 | -0.149 | 0.0875 | No | ||
177 | SDC2 | 1980168 | 13129 | -0.151 | 0.0872 | No | ||
178 | CDH2 | 520435 2450451 2760025 6650477 | 13303 | -0.164 | 0.0790 | No | ||
179 | MAST1 | 6940215 | 13676 | -0.197 | 0.0603 | No | ||
180 | HIVEP2 | 6520538 | 13738 | -0.203 | 0.0584 | No | ||
181 | SNAI1 | 6590253 | 13768 | -0.207 | 0.0584 | No | ||
182 | PPP2R5C | 3310121 6650672 | 13818 | -0.212 | 0.0573 | No | ||
183 | CITED2 | 5670114 5130088 | 13832 | -0.213 | 0.0581 | No | ||
184 | VPS13D | 2350451 | 13932 | -0.224 | 0.0544 | No | ||
185 | JPH1 | 610739 | 13987 | -0.230 | 0.0531 | No | ||
186 | GAD1 | 2360035 3140167 | 14087 | -0.240 | 0.0495 | No | ||
187 | TRPS1 | 870100 | 14346 | -0.274 | 0.0375 | No | ||
188 | RNF38 | 1940746 3140133 3840601 | 14408 | -0.283 | 0.0362 | No | ||
189 | TBC1D4 | 6420397 | 14563 | -0.312 | 0.0301 | No | ||
190 | UNC5A | 2120528 3060324 | 14565 | -0.312 | 0.0324 | No | ||
191 | ZMYND19 | 1570706 6860551 | 14577 | -0.314 | 0.0341 | No | ||
192 | AFF3 | 3870102 | 14584 | -0.315 | 0.0361 | No | ||
193 | GABRG2 | 2350402 4210204 6130279 6550037 | 14783 | -0.348 | 0.0278 | No | ||
194 | SNRP70 | 4200181 | 14833 | -0.355 | 0.0278 | No | ||
195 | FGF13 | 630575 1570440 5360121 | 14902 | -0.371 | 0.0268 | No | ||
196 | SPAG8 | 4280446 | 14919 | -0.374 | 0.0287 | No | ||
197 | SPRYD3 | 50403 | 15086 | -0.411 | 0.0226 | No | ||
198 | OVOL1 | 1690131 | 15093 | -0.412 | 0.0253 | No | ||
199 | KPNA4 | 510369 | 15378 | -0.482 | 0.0134 | No | ||
200 | LRP12 | 2370112 | 15485 | -0.517 | 0.0115 | No | ||
201 | TMEM16D | 2650324 | 15543 | -0.536 | 0.0123 | No | ||
202 | BCL2 | 730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164 | 15654 | -0.579 | 0.0105 | No | ||
203 | CHKB | 770129 | 15797 | -0.627 | 0.0074 | No | ||
204 | ANTXR1 | 1990593 2850056 | 15864 | -0.649 | 0.0086 | No | ||
205 | VAMP2 | 2100100 | 15915 | -0.674 | 0.0108 | No | ||
206 | ATP5A1 | 1990722 | 15925 | -0.679 | 0.0153 | No | ||
207 | ATAD2 | 870242 2260687 | 16159 | -0.780 | 0.0083 | No | ||
208 | VGLL4 | 6860463 | 16241 | -0.818 | 0.0099 | No | ||
209 | CRSP7 | 4230408 | 16370 | -0.877 | 0.0094 | No | ||
210 | EFNA3 | 6370390 | 16434 | -0.907 | 0.0126 | No | ||
211 | HIC2 | 4010433 | 16466 | -0.923 | 0.0177 | No | ||
212 | DOCK9 | 5080037 | 16476 | -0.930 | 0.0240 | No | ||
213 | OTUB1 | 610551 | 16684 | -1.014 | 0.0202 | No | ||
214 | LRIG1 | 1050136 | 16942 | -1.160 | 0.0147 | No | ||
215 | UBE2Q1 | 610348 2350114 4210717 | 16944 | -1.161 | 0.0232 | No | ||
216 | HNRPA0 | 2680048 | 17065 | -1.239 | 0.0257 | No | ||
217 | ANKRD50 | 870543 | 17144 | -1.290 | 0.0309 | No | ||
218 | IRF7 | 1570605 | 17457 | -1.493 | 0.0249 | No | ||
219 | PMP22 | 4010239 6550072 | 17493 | -1.521 | 0.0341 | No | ||
220 | SLC25A26 | 4210577 | 17588 | -1.593 | 0.0407 | No | ||
221 | USP21 | 3060446 | 18057 | -2.064 | 0.0304 | No |