Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
Upregulated in class | wtNotch |
GeneSet | ET743_SARCOMA_72HRS_DN |
Enrichment Score (ES) | 0.5693699 |
Normalized Enrichment Score (NES) | 1.7891061 |
Nominal p-value | 0.0 |
FDR q-value | 0.04980777 |
FWER p-Value | 0.226 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | SLC4A1AP | 3190576 | 14 | 3.866 | 0.0251 | Yes | ||
2 | LBR | 4540671 | 26 | 3.582 | 0.0484 | Yes | ||
3 | SMAD4 | 5670519 | 68 | 3.059 | 0.0666 | Yes | ||
4 | CCT4 | 6380161 | 71 | 3.052 | 0.0869 | Yes | ||
5 | OGT | 2360131 4610333 | 109 | 2.829 | 0.1037 | Yes | ||
6 | RAB1A | 2370671 | 140 | 2.727 | 0.1203 | Yes | ||
7 | RABGGTB | 3120037 | 152 | 2.678 | 0.1376 | Yes | ||
8 | DDX20 | 3290348 | 162 | 2.649 | 0.1548 | Yes | ||
9 | ATP2A2 | 1090075 3990279 | 164 | 2.633 | 0.1723 | Yes | ||
10 | PSMA4 | 4560427 | 198 | 2.539 | 0.1875 | Yes | ||
11 | PIK3C3 | 6590717 | 226 | 2.492 | 0.2027 | Yes | ||
12 | RABGAP1 | 5050397 | 236 | 2.466 | 0.2187 | Yes | ||
13 | CCNH | 3190347 | 309 | 2.289 | 0.2301 | Yes | ||
14 | RIPK1 | 3190025 | 325 | 2.264 | 0.2444 | Yes | ||
15 | TBK1 | 5690338 | 348 | 2.222 | 0.2580 | Yes | ||
16 | SLC25A17 | 2100369 | 370 | 2.189 | 0.2715 | Yes | ||
17 | HDAC2 | 4050433 | 372 | 2.188 | 0.2860 | Yes | ||
18 | FNTA | 70059 | 409 | 2.120 | 0.2982 | Yes | ||
19 | DDX21 | 6100446 | 442 | 2.073 | 0.3103 | Yes | ||
20 | GTF2H2 | 5130358 | 445 | 2.069 | 0.3241 | Yes | ||
21 | PJA2 | 430537 | 470 | 2.037 | 0.3364 | Yes | ||
22 | PSMD12 | 730044 | 488 | 2.007 | 0.3488 | Yes | ||
23 | PCNA | 940754 | 526 | 1.941 | 0.3598 | Yes | ||
24 | MAP3K7 | 6040068 | 534 | 1.929 | 0.3723 | Yes | ||
25 | UBE2D3 | 3190452 | 542 | 1.915 | 0.3847 | Yes | ||
26 | POLD3 | 6400278 | 553 | 1.899 | 0.3968 | Yes | ||
27 | SRPK2 | 6380341 | 580 | 1.872 | 0.4079 | Yes | ||
28 | RAP1B | 3710138 | 599 | 1.861 | 0.4194 | Yes | ||
29 | TNFSF5IP1 | 2060095 | 604 | 1.858 | 0.4316 | Yes | ||
30 | MCTS1 | 6130133 | 636 | 1.821 | 0.4421 | Yes | ||
31 | EXOC2 | 3190132 | 649 | 1.799 | 0.4534 | Yes | ||
32 | PPP2CB | 5570593 | 723 | 1.724 | 0.4610 | Yes | ||
33 | PPP2R5E | 70671 2120056 | 738 | 1.710 | 0.4716 | Yes | ||
34 | ELOVL6 | 5340746 | 816 | 1.633 | 0.4784 | Yes | ||
35 | TOP2A | 360717 | 909 | 1.531 | 0.4836 | Yes | ||
36 | XBP1 | 3840594 | 939 | 1.491 | 0.4920 | Yes | ||
37 | TMPO | 4050494 | 943 | 1.489 | 0.5018 | Yes | ||
38 | GTF2B | 6860685 | 1105 | 1.328 | 0.5019 | Yes | ||
39 | RBM17 | 870592 | 1168 | 1.265 | 0.5070 | Yes | ||
40 | HSPH1 | 1690017 | 1169 | 1.265 | 0.5155 | Yes | ||
41 | EMP1 | 4120438 | 1189 | 1.248 | 0.5228 | Yes | ||
42 | SIRT1 | 1190731 | 1245 | 1.201 | 0.5278 | Yes | ||
43 | SUPV3L1 | 1170072 | 1287 | 1.165 | 0.5334 | Yes | ||
44 | MAPK14 | 5290731 | 1301 | 1.150 | 0.5403 | Yes | ||
45 | UBE2D2 | 4590671 6510446 | 1363 | 1.102 | 0.5444 | Yes | ||
46 | TXNRD1 | 6590446 | 1371 | 1.098 | 0.5514 | Yes | ||
47 | GNL2 | 6620022 | 1381 | 1.088 | 0.5581 | Yes | ||
48 | MAT2A | 4070026 4730079 6020280 | 1555 | 0.995 | 0.5554 | Yes | ||
49 | ACTL6A | 5220543 6290541 2450093 4590332 5270722 | 1579 | 0.982 | 0.5607 | Yes | ||
50 | EML4 | 5700373 | 1651 | 0.941 | 0.5632 | Yes | ||
51 | FADD | 2360593 4210692 6520019 | 1712 | 0.901 | 0.5659 | Yes | ||
52 | STK17B | 130091 | 1757 | 0.874 | 0.5694 | Yes | ||
53 | BIRC2 | 2940435 4730020 | 1953 | 0.757 | 0.5639 | No | ||
54 | CCNA2 | 5290075 | 2176 | 0.634 | 0.5561 | No | ||
55 | RPS7 | 6860113 | 2215 | 0.615 | 0.5581 | No | ||
56 | ZDHHC5 | 1690711 | 2257 | 0.598 | 0.5599 | No | ||
57 | PSMC6 | 2810021 | 2356 | 0.560 | 0.5583 | No | ||
58 | ERCC3 | 6900008 | 2382 | 0.551 | 0.5606 | No | ||
59 | GABPB2 | 6130450 7050735 | 2416 | 0.538 | 0.5624 | No | ||
60 | BCL2L1 | 1580452 4200152 5420484 | 2532 | 0.495 | 0.5595 | No | ||
61 | JMJD2B | 6350372 6400471 | 2625 | 0.464 | 0.5576 | No | ||
62 | PRIM2A | 7000692 | 2657 | 0.456 | 0.5590 | No | ||
63 | GCNT1 | 940129 1780215 2370253 | 2747 | 0.424 | 0.5570 | No | ||
64 | GTF2H1 | 2570746 2650148 | 2751 | 0.423 | 0.5596 | No | ||
65 | SMARCA5 | 6620050 | 2774 | 0.416 | 0.5612 | No | ||
66 | FBXL3 | 5910142 | 2852 | 0.387 | 0.5596 | No | ||
67 | MRPL15 | 360390 | 2896 | 0.375 | 0.5598 | No | ||
68 | SNRPG | 2340551 | 2963 | 0.353 | 0.5586 | No | ||
69 | ARFGEF2 | 5550500 | 2985 | 0.346 | 0.5598 | No | ||
70 | PSMB1 | 2940402 | 3086 | 0.317 | 0.5565 | No | ||
71 | CORO1C | 4570397 | 3248 | 0.278 | 0.5496 | No | ||
72 | PPP1CC | 6380300 2510647 | 3376 | 0.251 | 0.5444 | No | ||
73 | FNDC3A | 2690097 3290044 | 3438 | 0.236 | 0.5426 | No | ||
74 | USP12 | 6130735 6620280 | 3514 | 0.221 | 0.5401 | No | ||
75 | CDC5L | 3130446 3390025 6400204 | 3771 | 0.177 | 0.5274 | No | ||
76 | GOPC | 6620400 | 3841 | 0.168 | 0.5248 | No | ||
77 | WEE1 | 3390070 | 3884 | 0.160 | 0.5235 | No | ||
78 | SSFA2 | 3870133 | 4070 | 0.139 | 0.5144 | No | ||
79 | CYHR1 | 940609 2810463 3190332 3290692 4280411 | 4169 | 0.130 | 0.5100 | No | ||
80 | CDC25C | 2570673 4760161 6520707 | 4241 | 0.124 | 0.5070 | No | ||
81 | SFRS9 | 3800047 | 4373 | 0.112 | 0.5006 | No | ||
82 | RBM27 | 4050603 | 5142 | 0.067 | 0.4595 | No | ||
83 | CDC23 | 3190593 | 5157 | 0.066 | 0.4591 | No | ||
84 | PRKD3 | 5220520 5890519 | 5270 | 0.061 | 0.4535 | No | ||
85 | TCERG1 | 2350551 4540397 5220746 | 5343 | 0.059 | 0.4500 | No | ||
86 | LYN | 6040600 | 5608 | 0.048 | 0.4360 | No | ||
87 | MTIF2 | 2260270 | 5968 | 0.038 | 0.4168 | No | ||
88 | MYC | 380541 4670170 | 6382 | 0.028 | 0.3946 | No | ||
89 | CRK | 1230162 4780128 | 6649 | 0.022 | 0.3803 | No | ||
90 | GGPS1 | 840128 2320215 | 6655 | 0.022 | 0.3802 | No | ||
91 | SPRY2 | 5860184 | 6772 | 0.019 | 0.3740 | No | ||
92 | PLAG1 | 1450142 3870139 6520039 | 6905 | 0.017 | 0.3670 | No | ||
93 | TDG | 2900358 2940079 | 6908 | 0.017 | 0.3670 | No | ||
94 | VEGFC | 5910494 | 7045 | 0.014 | 0.3597 | No | ||
95 | GDI2 | 2370068 | 7070 | 0.014 | 0.3585 | No | ||
96 | NCOA6 | 1780333 6450110 | 7155 | 0.012 | 0.3540 | No | ||
97 | FBXL7 | 6620711 | 7254 | 0.010 | 0.3488 | No | ||
98 | ATG5 | 6200433 5360324 | 7584 | 0.005 | 0.3310 | No | ||
99 | CFLAR | 2320605 6180440 | 8009 | -0.002 | 0.3080 | No | ||
100 | MRPL35 | 1990671 | 8038 | -0.002 | 0.3065 | No | ||
101 | BUB1 | 5390270 | 8457 | -0.009 | 0.2839 | No | ||
102 | MFAP1 | 6660092 | 8806 | -0.015 | 0.2652 | No | ||
103 | XRCC5 | 7100286 | 8895 | -0.016 | 0.2605 | No | ||
104 | FZD1 | 3140215 | 9077 | -0.020 | 0.2508 | No | ||
105 | ACSL3 | 3140195 | 9151 | -0.021 | 0.2470 | No | ||
106 | EPS8 | 7050204 | 9559 | -0.028 | 0.2251 | No | ||
107 | FOSL1 | 430021 | 9630 | -0.029 | 0.2215 | No | ||
108 | CRSP6 | 2940358 | 9663 | -0.029 | 0.2200 | No | ||
109 | ARHGEF2 | 3360577 | 10092 | -0.038 | 0.1970 | No | ||
110 | JAG1 | 3440390 | 10141 | -0.039 | 0.1947 | No | ||
111 | RAB5A | 6520324 | 10144 | -0.039 | 0.1948 | No | ||
112 | CXXC5 | 840010 | 10210 | -0.040 | 0.1916 | No | ||
113 | IPO7 | 2190746 | 10270 | -0.041 | 0.1887 | No | ||
114 | CDK7 | 2640451 | 10877 | -0.056 | 0.1562 | No | ||
115 | CDH11 | 1230133 2100180 4610110 | 11003 | -0.059 | 0.1498 | No | ||
116 | BIRC6 | 70148 | 11038 | -0.060 | 0.1484 | No | ||
117 | CPT1A | 6350093 | 11308 | -0.067 | 0.1342 | No | ||
118 | TIAM2 | 360195 | 11492 | -0.072 | 0.1248 | No | ||
119 | HSPA1L | 4010538 | 11494 | -0.073 | 0.1252 | No | ||
120 | EIF4B | 5390563 5270577 | 11766 | -0.082 | 0.1111 | No | ||
121 | RNF14 | 50402 1340041 6370687 | 11898 | -0.087 | 0.1046 | No | ||
122 | HS3ST3B1 | 380040 | 12146 | -0.096 | 0.0918 | No | ||
123 | NUFIP1 | 6350241 | 12273 | -0.102 | 0.0857 | No | ||
124 | CTGF | 4540577 | 12887 | -0.135 | 0.0534 | No | ||
125 | B4GALT5 | 1230692 | 12944 | -0.138 | 0.0512 | No | ||
126 | MCM3 | 5570068 | 13403 | -0.172 | 0.0276 | No | ||
127 | UBE2C | 6130017 | 13412 | -0.173 | 0.0283 | No | ||
128 | MTMR4 | 4540524 | 13560 | -0.186 | 0.0216 | No | ||
129 | ANLN | 1780113 2470537 6840047 | 13567 | -0.187 | 0.0225 | No | ||
130 | PAPPA | 4230463 | 13720 | -0.202 | 0.0156 | No | ||
131 | HSPA8 | 2120315 1050132 6550746 | 13775 | -0.208 | 0.0141 | No | ||
132 | SEH1L | 4590563 | 13777 | -0.208 | 0.0154 | No | ||
133 | THRAP3 | 6180309 | 13863 | -0.216 | 0.0122 | No | ||
134 | IL1RL1 | 3990224 6020347 | 14024 | -0.235 | 0.0051 | No | ||
135 | RCC1 | 2480358 | 14128 | -0.246 | 0.0012 | No | ||
136 | FAS | 4480112 6110040 | 14139 | -0.247 | 0.0023 | No | ||
137 | PSMA5 | 5390537 | 14212 | -0.258 | 0.0001 | No | ||
138 | ADSL | 5570484 | 14229 | -0.261 | 0.0010 | No | ||
139 | MRPL1 | 430626 3130129 5220152 | 14393 | -0.280 | -0.0060 | No | ||
140 | EIF3S10 | 1190079 3840176 | 15047 | -0.403 | -0.0387 | No | ||
141 | CLCN7 | 2970095 | 15065 | -0.407 | -0.0369 | No | ||
142 | EPS15 | 4200215 | 15079 | -0.410 | -0.0348 | No | ||
143 | PDGFB | 3060440 6370008 | 15107 | -0.414 | -0.0335 | No | ||
144 | BUB3 | 3170546 | 15220 | -0.440 | -0.0367 | No | ||
145 | BLZF1 | 630088 | 15405 | -0.491 | -0.0434 | No | ||
146 | DLG5 | 450215 | 15777 | -0.620 | -0.0593 | No | ||
147 | ZDHHC16 | 4230390 | 16170 | -0.783 | -0.0754 | No | ||
148 | ARFGAP1 | 4780364 5390358 | 16223 | -0.808 | -0.0728 | No | ||
149 | DNAJA2 | 2630253 6860358 | 16239 | -0.817 | -0.0681 | No | ||
150 | USP3 | 2060332 | 16345 | -0.870 | -0.0680 | No | ||
151 | CHST2 | 3180682 | 16367 | -0.876 | -0.0633 | No | ||
152 | MID1IP1 | 2570739 | 16440 | -0.910 | -0.0611 | No | ||
153 | TARDBP | 870390 2350093 | 16452 | -0.917 | -0.0556 | No | ||
154 | SON | 3120148 5860239 7040403 | 16514 | -0.945 | -0.0526 | No | ||
155 | TOP1 | 770471 4060632 6650324 | 16558 | -0.968 | -0.0485 | No | ||
156 | SIRPA | 130465 5700332 | 16718 | -1.028 | -0.0502 | No | ||
157 | PANX1 | 6550632 | 16755 | -1.045 | -0.0452 | No | ||
158 | FKBP1A | 2450368 | 16894 | -1.130 | -0.0451 | No | ||
159 | SNIP1 | 5360092 | 17577 | -1.585 | -0.0715 | No | ||
160 | BAG2 | 2900324 | 17691 | -1.693 | -0.0663 | No | ||
161 | RBM14 | 5340731 5690315 | 17794 | -1.791 | -0.0599 | No | ||
162 | SLC2A1 | 2100609 | 17911 | -1.907 | -0.0534 | No | ||
163 | HSPE1 | 3170438 | 18090 | -2.106 | -0.0490 | No | ||
164 | GIPC1 | 4590348 5570438 5900707 | 18209 | -2.263 | -0.0403 | No | ||
165 | LHFPL2 | 450020 | 18245 | -2.327 | -0.0267 | No | ||
166 | KIAA0859 | 510497 770722 1340687 6840711 | 18320 | -2.453 | -0.0143 | No | ||
167 | WNT5B | 5080162 | 18606 | -4.536 | 0.0005 | No |