Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_wtNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch.phenotype_truncNotch_versus_wtNotch.cls #wtNotch_versus_truncNotch_repos |
| Phenotype | phenotype_truncNotch_versus_wtNotch.cls#wtNotch_versus_truncNotch_repos |
| Upregulated in class | wtNotch |
| GeneSet | REACTOME_G2_M_CHECKPOINTS |
| Enrichment Score (ES) | 0.6875529 |
| Normalized Enrichment Score (NES) | 1.699147 |
| Nominal p-value | 0.0070093456 |
| FDR q-value | 0.13428247 |
| FWER p-Value | 0.542 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | RFC4 | 3800082 6840142 | 64 | 3.081 | 0.1335 | Yes | ||
| 2 | CCNB1 | 4590433 4780372 | 211 | 2.518 | 0.2376 | Yes | ||
| 3 | RPA1 | 360452 | 385 | 2.159 | 0.3243 | Yes | ||
| 4 | CDC7 | 4060546 4850041 | 725 | 1.718 | 0.3825 | Yes | ||
| 5 | RPA3 | 5700136 | 821 | 1.631 | 0.4499 | Yes | ||
| 6 | MCM4 | 2760673 5420711 | 904 | 1.538 | 0.5139 | Yes | ||
| 7 | ORC5L | 1940133 1940711 | 1013 | 1.414 | 0.5710 | Yes | ||
| 8 | MCM6 | 60092 540181 6510110 | 1822 | 0.831 | 0.5644 | Yes | ||
| 9 | RAD9B | 2320064 | 2007 | 0.722 | 0.5866 | Yes | ||
| 10 | CDC45L | 70537 3130114 | 2050 | 0.690 | 0.6151 | Yes | ||
| 11 | CDC25A | 3800184 | 2212 | 0.617 | 0.6338 | Yes | ||
| 12 | MCM7 | 3290292 5220056 | 2334 | 0.569 | 0.6526 | Yes | ||
| 13 | HUS1 | 3440494 3800156 | 2429 | 0.533 | 0.6712 | Yes | ||
| 14 | ORC4L | 4230538 5550288 | 2535 | 0.494 | 0.6876 | Yes | ||
| 15 | CDK2 | 130484 2260301 4010088 5050110 | 3216 | 0.284 | 0.6636 | No | ||
| 16 | RPA2 | 2760301 5420195 | 3221 | 0.283 | 0.6760 | No | ||
| 17 | ORC1L | 2370328 6110390 | 3473 | 0.230 | 0.6727 | No | ||
| 18 | WEE1 | 3390070 | 3884 | 0.160 | 0.6577 | No | ||
| 19 | ORC2L | 1990470 6510019 | 4029 | 0.144 | 0.6564 | No | ||
| 20 | CDC25C | 2570673 4760161 6520707 | 4241 | 0.124 | 0.6506 | No | ||
| 21 | ATM | 3610110 4050524 | 4686 | 0.090 | 0.6307 | No | ||
| 22 | MCM10 | 4920632 | 5254 | 0.062 | 0.6029 | No | ||
| 23 | CHEK1 | 50167 1940300 | 5327 | 0.059 | 0.6017 | No | ||
| 24 | CCNB2 | 6510528 | 5570 | 0.050 | 0.5909 | No | ||
| 25 | RFC3 | 1980600 | 11471 | -0.072 | 0.2766 | No | ||
| 26 | RAD1 | 4200551 | 12723 | -0.125 | 0.2149 | No | ||
| 27 | MCM3 | 5570068 | 13403 | -0.172 | 0.1860 | No | ||
| 28 | MCM5 | 2680647 | 15085 | -0.411 | 0.1138 | No | ||
| 29 | MCM2 | 5050139 | 15297 | -0.459 | 0.1229 | No | ||
| 30 | RFC5 | 3800452 6020091 | 17085 | -1.251 | 0.0824 | No |
