Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | wtNotch |
GeneSet | V$USF_C |
Enrichment Score (ES) | 0.47999826 |
Normalized Enrichment Score (NES) | 1.3600389 |
Nominal p-value | 0.017142856 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | TIMM10 | 610070 1450019 | 3 | 9.579 | 0.0515 | Yes | ||
2 | AKAP12 | 1450739 | 58 | 5.480 | 0.0781 | Yes | ||
3 | FBL | 5130020 | 61 | 5.340 | 0.1068 | Yes | ||
4 | LYAR | 7000402 | 94 | 4.799 | 0.1309 | Yes | ||
5 | RPS19 | 5860066 | 163 | 4.257 | 0.1502 | Yes | ||
6 | EXOSC5 | 3370671 | 167 | 4.220 | 0.1728 | Yes | ||
7 | PA2G4 | 2030463 | 194 | 4.069 | 0.1933 | Yes | ||
8 | G6PC3 | 1580487 5390253 | 220 | 3.945 | 0.2132 | Yes | ||
9 | ABCB6 | 6350138 | 302 | 3.607 | 0.2283 | Yes | ||
10 | EXOSC2 | 6900471 | 333 | 3.477 | 0.2454 | Yes | ||
11 | PFDN2 | 4230156 | 348 | 3.411 | 0.2630 | Yes | ||
12 | PPAT | 1980019 | 351 | 3.407 | 0.2813 | Yes | ||
13 | NUDC | 4780025 | 395 | 3.235 | 0.2964 | Yes | ||
14 | HMOX1 | 1740687 | 407 | 3.190 | 0.3130 | Yes | ||
15 | IPO4 | 5050619 | 442 | 3.084 | 0.3278 | Yes | ||
16 | OPRS1 | 6130128 6290717 | 496 | 2.961 | 0.3409 | Yes | ||
17 | SDC1 | 3440471 6350408 | 522 | 2.876 | 0.3550 | Yes | ||
18 | EIF4B | 5390563 5270577 | 653 | 2.610 | 0.3621 | Yes | ||
19 | HYAL2 | 1500152 | 697 | 2.535 | 0.3734 | Yes | ||
20 | EIF2C2 | 770451 | 739 | 2.467 | 0.3845 | Yes | ||
21 | HMGN2 | 3140091 | 779 | 2.385 | 0.3952 | Yes | ||
22 | FKBP11 | 3170575 | 979 | 2.067 | 0.3956 | Yes | ||
23 | GPD1 | 2480095 | 1032 | 1.991 | 0.4035 | Yes | ||
24 | HSPE1 | 3170438 | 1121 | 1.886 | 0.4089 | Yes | ||
25 | PAICS | 610142 | 1131 | 1.879 | 0.4185 | Yes | ||
26 | ENO3 | 5270136 | 1206 | 1.805 | 0.4242 | Yes | ||
27 | PSMB3 | 4280594 | 1211 | 1.799 | 0.4337 | Yes | ||
28 | SRP72 | 3990427 | 1241 | 1.774 | 0.4417 | Yes | ||
29 | POLR3E | 380152 | 1338 | 1.679 | 0.4456 | Yes | ||
30 | RPL22 | 4070070 | 1401 | 1.628 | 0.4510 | Yes | ||
31 | HERPUD1 | 7100440 | 1584 | 1.449 | 0.4489 | Yes | ||
32 | EIF4G1 | 4070446 | 1619 | 1.417 | 0.4547 | Yes | ||
33 | MYOHD1 | 1410520 | 1832 | 1.246 | 0.4499 | Yes | ||
34 | BCL9L | 6940053 | 1877 | 1.210 | 0.4541 | Yes | ||
35 | FHOD1 | 2680279 | 1942 | 1.155 | 0.4568 | Yes | ||
36 | SH3KBP1 | 670102 2850458 7000309 | 1990 | 1.112 | 0.4603 | Yes | ||
37 | PABPC4 | 1990170 6760270 5390138 | 2166 | 1.001 | 0.4562 | Yes | ||
38 | PABPC1 | 2650180 2690253 6020632 1990270 | 2171 | 1.000 | 0.4613 | Yes | ||
39 | IVNS1ABP | 4760601 6520113 | 2343 | 0.915 | 0.4570 | Yes | ||
40 | ANXA6 | 2190014 | 2422 | 0.865 | 0.4574 | Yes | ||
41 | MORF4L2 | 6450133 | 2431 | 0.863 | 0.4616 | Yes | ||
42 | POLR2H | 5890242 | 2498 | 0.821 | 0.4625 | Yes | ||
43 | MPP3 | 1400056 4480411 6770168 | 2567 | 0.777 | 0.4630 | Yes | ||
44 | MYST3 | 5270500 | 2576 | 0.772 | 0.4667 | Yes | ||
45 | SLC39A7 | 5570131 | 2604 | 0.758 | 0.4693 | Yes | ||
46 | STMN1 | 1990717 | 2698 | 0.711 | 0.4681 | Yes | ||
47 | CACNA1D | 1740315 4730731 | 2744 | 0.682 | 0.4694 | Yes | ||
48 | PSEN2 | 130382 | 2754 | 0.678 | 0.4725 | Yes | ||
49 | GTF2H1 | 2570746 2650148 | 2773 | 0.670 | 0.4752 | Yes | ||
50 | PPARGC1B | 3290114 | 2786 | 0.666 | 0.4781 | Yes | ||
51 | CDC14A | 4050132 | 2817 | 0.652 | 0.4800 | Yes | ||
52 | B4GALT2 | 780037 | 3016 | 0.565 | 0.4723 | No | ||
53 | UBE1 | 4150139 7050463 | 3061 | 0.550 | 0.4729 | No | ||
54 | TIMM9 | 2450484 | 3293 | 0.460 | 0.4628 | No | ||
55 | CNNM1 | 2190433 | 3583 | 0.365 | 0.4491 | No | ||
56 | RUNX2 | 1400193 4230215 | 3628 | 0.345 | 0.4486 | No | ||
57 | FARP1 | 5290102 7100341 | 3678 | 0.330 | 0.4477 | No | ||
58 | AMPD2 | 630093 1170070 | 3701 | 0.323 | 0.4483 | No | ||
59 | SLC26A2 | 2360278 | 3949 | 0.265 | 0.4363 | No | ||
60 | SYT3 | 6380017 | 3959 | 0.262 | 0.4372 | No | ||
61 | TNFRSF21 | 6380100 | 3992 | 0.253 | 0.4368 | No | ||
62 | ARRDC3 | 4610390 | 4025 | 0.249 | 0.4364 | No | ||
63 | BHLHB2 | 7040603 | 4140 | 0.228 | 0.4315 | No | ||
64 | TIAL1 | 4150048 6510605 | 4148 | 0.228 | 0.4323 | No | ||
65 | NLN | 1450576 5870575 | 4229 | 0.214 | 0.4291 | No | ||
66 | UBXD3 | 5050193 | 4242 | 0.212 | 0.4296 | No | ||
67 | SUCLG2 | 5340397 5700270 | 4269 | 0.208 | 0.4294 | No | ||
68 | CAMK4 | 1690091 | 4340 | 0.200 | 0.4266 | No | ||
69 | SOCS5 | 3830398 7100093 | 4608 | 0.167 | 0.4130 | No | ||
70 | ALDH3B1 | 4210010 6940403 | 4722 | 0.156 | 0.4078 | No | ||
71 | AVP | 2100113 | 4724 | 0.156 | 0.4085 | No | ||
72 | EFNB1 | 2970433 | 4725 | 0.156 | 0.4094 | No | ||
73 | DAZAP1 | 5890563 | 4777 | 0.151 | 0.4074 | No | ||
74 | NR1D1 | 2360471 770746 6590204 | 5147 | 0.122 | 0.3881 | No | ||
75 | GTF2A1 | 4120138 4920524 5390110 1230397 | 5255 | 0.115 | 0.3829 | No | ||
76 | HOXA3 | 3610632 6020358 | 5397 | 0.107 | 0.3758 | No | ||
77 | HSPH1 | 1690017 | 5486 | 0.102 | 0.3716 | No | ||
78 | GPRC5C | 1580372 | 5528 | 0.100 | 0.3699 | No | ||
79 | SYT6 | 2510280 3850128 4540064 | 5583 | 0.098 | 0.3675 | No | ||
80 | SEMA7A | 2630239 5050593 | 5594 | 0.097 | 0.3675 | No | ||
81 | HS3ST3A1 | 2230497 | 5988 | 0.079 | 0.3466 | No | ||
82 | XRN2 | 130603 1230113 4230309 | 5998 | 0.079 | 0.3465 | No | ||
83 | RUSC1 | 6450093 6980575 | 6058 | 0.076 | 0.3437 | No | ||
84 | COL2A1 | 460446 3940500 | 6227 | 0.070 | 0.3350 | No | ||
85 | PIGW | 4810072 | 6375 | 0.065 | 0.3274 | No | ||
86 | SC5DL | 6650390 | 6447 | 0.062 | 0.3238 | No | ||
87 | TBX4 | 3060008 | 6450 | 0.062 | 0.3241 | No | ||
88 | LTBR | 2450341 | 6473 | 0.061 | 0.3232 | No | ||
89 | NXPH1 | 3870546 | 6731 | 0.054 | 0.3096 | No | ||
90 | SGTB | 460170 | 6886 | 0.050 | 0.3015 | No | ||
91 | FGF14 | 2630390 3520075 6770048 | 7005 | 0.048 | 0.2953 | No | ||
92 | ELOVL4 | 5220333 | 7010 | 0.047 | 0.2954 | No | ||
93 | KIAA0427 | 1690435 | 7062 | 0.046 | 0.2928 | No | ||
94 | DNAJB9 | 460114 | 7132 | 0.044 | 0.2893 | No | ||
95 | BMP4 | 380113 | 7134 | 0.044 | 0.2895 | No | ||
96 | ETV1 | 70735 2940603 5080463 | 7339 | 0.040 | 0.2787 | No | ||
97 | PLA2G4A | 6380364 | 7405 | 0.039 | 0.2754 | No | ||
98 | DRD1 | 430025 | 7409 | 0.039 | 0.2754 | No | ||
99 | LIN28 | 6590672 | 7537 | 0.036 | 0.2687 | No | ||
100 | SLC12A5 | 1980692 | 7692 | 0.033 | 0.2605 | No | ||
101 | RHEBL1 | 2810576 | 7702 | 0.033 | 0.2602 | No | ||
102 | DNMT3A | 4050068 4810717 | 7769 | 0.032 | 0.2568 | No | ||
103 | POGK | 5290315 | 7921 | 0.029 | 0.2488 | No | ||
104 | SATB2 | 2470181 | 7951 | 0.028 | 0.2473 | No | ||
105 | HOXC12 | 5270411 | 8100 | 0.026 | 0.2395 | No | ||
106 | HOXC13 | 4070722 | 8173 | 0.024 | 0.2357 | No | ||
107 | BMP2K | 60541 5570504 | 8196 | 0.024 | 0.2346 | No | ||
108 | GRIN2A | 6550538 | 8547 | 0.018 | 0.2157 | No | ||
109 | CGN | 5890139 6370167 6400537 | 8549 | 0.018 | 0.2158 | No | ||
110 | FGF11 | 840292 | 8837 | 0.013 | 0.2003 | No | ||
111 | CHRM1 | 4280619 | 9255 | 0.007 | 0.1777 | No | ||
112 | TLL1 | 2680315 | 9308 | 0.006 | 0.1749 | No | ||
113 | SNX5 | 1570021 6860609 | 9426 | 0.004 | 0.1686 | No | ||
114 | LAP3 | 2570064 | 9787 | -0.001 | 0.1490 | No | ||
115 | CTSF | 6100021 | 9893 | -0.003 | 0.1433 | No | ||
116 | LRP8 | 3610746 5360035 | 9894 | -0.003 | 0.1434 | No | ||
117 | SIRT1 | 1190731 | 10156 | -0.007 | 0.1292 | No | ||
118 | ARX | 6900504 | 10560 | -0.013 | 0.1074 | No | ||
119 | MTHFD1 | 5900398 6520427 | 10575 | -0.013 | 0.1067 | No | ||
120 | NKX2-3 | 1990736 6940088 | 10781 | -0.016 | 0.0957 | No | ||
121 | LHX9 | 2350112 | 10874 | -0.018 | 0.0908 | No | ||
122 | ABCA1 | 6290156 | 10877 | -0.018 | 0.0908 | No | ||
123 | FADS3 | 3120079 | 10921 | -0.018 | 0.0886 | No | ||
124 | ENPP6 | 110524 580563 | 10945 | -0.019 | 0.0874 | No | ||
125 | MAX | 5220021 | 11147 | -0.022 | 0.0766 | No | ||
126 | PRKCE | 5700053 | 11229 | -0.024 | 0.0724 | No | ||
127 | PAX6 | 1190025 | 11552 | -0.029 | 0.0551 | No | ||
128 | SLC6A15 | 5290176 6040017 | 11562 | -0.029 | 0.0547 | No | ||
129 | EIF3S1 | 6130368 6770044 | 11684 | -0.032 | 0.0483 | No | ||
130 | HPCA | 6860010 | 11860 | -0.036 | 0.0390 | No | ||
131 | NPM1 | 4730427 | 11866 | -0.036 | 0.0389 | No | ||
132 | FLT3 | 2640487 | 12169 | -0.042 | 0.0228 | No | ||
133 | SET | 6650286 | 12430 | -0.048 | 0.0089 | No | ||
134 | TDRD1 | 4230301 6110750 | 12545 | -0.052 | 0.0030 | No | ||
135 | SCFD2 | 2480504 | 12606 | -0.053 | 0.0001 | No | ||
136 | EEF1E1 | 4540711 | 12817 | -0.060 | -0.0110 | No | ||
137 | IPO13 | 3870088 | 12934 | -0.064 | -0.0169 | No | ||
138 | WEE1 | 3390070 | 13037 | -0.067 | -0.0221 | No | ||
139 | HPCAL4 | 2600484 | 13162 | -0.072 | -0.0285 | No | ||
140 | DAZL | 4050082 | 13213 | -0.074 | -0.0308 | No | ||
141 | NPTX1 | 3710736 | 13357 | -0.081 | -0.0381 | No | ||
142 | HHIP | 6940438 | 13401 | -0.083 | -0.0400 | No | ||
143 | ADAMTS17 | 6510739 | 13481 | -0.087 | -0.0438 | No | ||
144 | SNCAIP | 4010551 | 13535 | -0.089 | -0.0462 | No | ||
145 | CHST11 | 6760546 | 13550 | -0.090 | -0.0465 | No | ||
146 | ETV4 | 2450605 | 14012 | -0.121 | -0.0708 | No | ||
147 | CNOT4 | 2320242 6760706 | 14209 | -0.140 | -0.0807 | No | ||
148 | MCM8 | 6130743 | 14383 | -0.157 | -0.0892 | No | ||
149 | CLCN2 | 1940021 | 14501 | -0.169 | -0.0947 | No | ||
150 | ADCY3 | 2350347 3440242 | 14667 | -0.190 | -0.1026 | No | ||
151 | RPL13A | 2680519 5700142 | 14763 | -0.207 | -0.1067 | No | ||
152 | PER1 | 3290315 | 14765 | -0.207 | -0.1056 | No | ||
153 | PTMA | 5570148 | 15281 | -0.334 | -0.1317 | No | ||
154 | HOXA4 | 940152 | 15401 | -0.369 | -0.1362 | No | ||
155 | RXRB | 1780040 5340438 | 15496 | -0.407 | -0.1391 | No | ||
156 | SLC31A2 | 1450577 | 15516 | -0.417 | -0.1379 | No | ||
157 | BCKDHA | 50189 | 15764 | -0.528 | -0.1484 | No | ||
158 | TEF | 1050050 3120397 4060487 | 15768 | -0.529 | -0.1458 | No | ||
159 | CRMP1 | 4810014 | 15989 | -0.646 | -0.1542 | No | ||
160 | GRK6 | 1500053 | 16014 | -0.659 | -0.1520 | No | ||
161 | MNT | 4920575 | 16146 | -0.736 | -0.1551 | No | ||
162 | MAT2A | 4070026 4730079 6020280 | 16267 | -0.813 | -0.1572 | No | ||
163 | MXD4 | 4810113 | 16347 | -0.865 | -0.1568 | No | ||
164 | EIF4E | 1580403 70133 6380215 | 16348 | -0.866 | -0.1522 | No | ||
165 | HSPA4 | 1050170 3450309 | 16403 | -0.901 | -0.1502 | No | ||
166 | RPL19 | 5550592 | 16436 | -0.918 | -0.1470 | No | ||
167 | CENTB5 | 5690128 | 16710 | -1.093 | -0.1560 | No | ||
168 | GNA13 | 4590102 | 16772 | -1.147 | -0.1531 | No | ||
169 | GPX1 | 4150093 | 16775 | -1.150 | -0.1470 | No | ||
170 | USP2 | 1190292 1240253 4850035 | 16789 | -1.162 | -0.1414 | No | ||
171 | PDK2 | 2690017 | 16814 | -1.184 | -0.1363 | No | ||
172 | H3F3A | 2900086 | 16833 | -1.191 | -0.1309 | No | ||
173 | ARF6 | 3520026 | 16977 | -1.316 | -0.1316 | No | ||
174 | HSPBAP1 | 4060022 | 17181 | -1.572 | -0.1341 | No | ||
175 | FCHSD2 | 5720092 | 17198 | -1.593 | -0.1264 | No | ||
176 | PFN1 | 6130132 | 17292 | -1.714 | -0.1222 | No | ||
177 | SLC20A1 | 6420014 | 17320 | -1.735 | -0.1143 | No | ||
178 | EIF5A | 1500059 5290022 6370026 | 17435 | -1.918 | -0.1101 | No | ||
179 | BCAS3 | 4050647 | 17532 | -2.092 | -0.1041 | No | ||
180 | ACVR2B | 1660546 | 17634 | -2.309 | -0.0971 | No | ||
181 | GABARAP | 1450286 | 18075 | -3.356 | -0.1029 | No | ||
182 | DIABLO | 2360170 | 18180 | -3.751 | -0.0883 | No | ||
183 | PPP1R9B | 3130619 | 18306 | -4.410 | -0.0713 | No | ||
184 | BCL6 | 940100 | 18397 | -5.006 | -0.0492 | No | ||
185 | WBP2 | 3170128 | 18414 | -5.182 | -0.0221 | No | ||
186 | RORC | 1740121 | 18500 | -6.120 | 0.0063 | No |