Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | wtNotch |
GeneSet | V$NMYC_01 |
Enrichment Score (ES) | 0.54729193 |
Normalized Enrichment Score (NES) | 1.5375322 |
Nominal p-value | 0.0 |
FDR q-value | 0.20158345 |
FWER p-Value | 0.62 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | TIMM10 | 610070 1450019 | 3 | 9.579 | 0.0564 | Yes | ||
2 | VARS2 | 1410017 3800114 4210270 | 31 | 6.628 | 0.0941 | Yes | ||
3 | CEBPB | 2970019 | 35 | 6.268 | 0.1310 | Yes | ||
4 | ATAD3A | 4050288 | 44 | 5.911 | 0.1655 | Yes | ||
5 | FBL | 5130020 | 61 | 5.340 | 0.1962 | Yes | ||
6 | VPS16 | 430064 3390041 6860301 | 148 | 4.381 | 0.2174 | Yes | ||
7 | PA2G4 | 2030463 | 194 | 4.069 | 0.2390 | Yes | ||
8 | G6PC3 | 1580487 5390253 | 220 | 3.945 | 0.2609 | Yes | ||
9 | ATP5G1 | 5290019 | 245 | 3.817 | 0.2822 | Yes | ||
10 | BCL7C | 460050 | 304 | 3.591 | 0.3002 | Yes | ||
11 | PPAT | 1980019 | 351 | 3.407 | 0.3179 | Yes | ||
12 | FKBP5 | 2190048 | 369 | 3.340 | 0.3367 | Yes | ||
13 | HMOX1 | 1740687 | 407 | 3.190 | 0.3535 | Yes | ||
14 | PRDX4 | 3800039 | 438 | 3.094 | 0.3702 | Yes | ||
15 | IPO4 | 5050619 | 442 | 3.084 | 0.3882 | Yes | ||
16 | EIF4B | 5390563 5270577 | 653 | 2.610 | 0.3923 | Yes | ||
17 | HYAL2 | 1500152 | 697 | 2.535 | 0.4049 | Yes | ||
18 | LMNB1 | 5890292 6020008 | 756 | 2.426 | 0.4161 | Yes | ||
19 | NOL5A | 5570139 | 757 | 2.422 | 0.4304 | Yes | ||
20 | HMGN2 | 3140091 | 779 | 2.385 | 0.4433 | Yes | ||
21 | GPD1 | 2480095 | 1032 | 1.991 | 0.4414 | Yes | ||
22 | COPS7A | 3940458 7000022 | 1085 | 1.933 | 0.4500 | Yes | ||
23 | HSPE1 | 3170438 | 1121 | 1.886 | 0.4593 | Yes | ||
24 | DLX1 | 360168 | 1144 | 1.861 | 0.4691 | Yes | ||
25 | SRP72 | 3990427 | 1241 | 1.774 | 0.4744 | Yes | ||
26 | ELOVL6 | 5340746 | 1279 | 1.733 | 0.4826 | Yes | ||
27 | POLR3E | 380152 | 1338 | 1.679 | 0.4894 | Yes | ||
28 | RPL22 | 4070070 | 1401 | 1.628 | 0.4956 | Yes | ||
29 | ZCCHC7 | 6510592 | 1453 | 1.582 | 0.5022 | Yes | ||
30 | EIF4G1 | 4070446 | 1619 | 1.417 | 0.5016 | Yes | ||
31 | PES1 | 2470427 | 1642 | 1.402 | 0.5087 | Yes | ||
32 | GTPBP1 | 2230541 4560528 | 1661 | 1.384 | 0.5159 | Yes | ||
33 | LIG3 | 2940300 | 1694 | 1.358 | 0.5222 | Yes | ||
34 | FKBP10 | 1340706 | 1724 | 1.328 | 0.5285 | Yes | ||
35 | KRTCAP2 | 5220040 | 1759 | 1.298 | 0.5343 | Yes | ||
36 | FHOD1 | 2680279 | 1942 | 1.155 | 0.5313 | Yes | ||
37 | SH3KBP1 | 670102 2850458 7000309 | 1990 | 1.112 | 0.5353 | Yes | ||
38 | HSPD1 | 60097 2030451 | 2084 | 1.045 | 0.5364 | Yes | ||
39 | PABPC4 | 1990170 6760270 5390138 | 2166 | 1.001 | 0.5379 | Yes | ||
40 | PABPC1 | 2650180 2690253 6020632 1990270 | 2171 | 1.000 | 0.5436 | Yes | ||
41 | ANXA6 | 2190014 | 2422 | 0.865 | 0.5352 | Yes | ||
42 | MYST3 | 5270500 | 2576 | 0.772 | 0.5314 | Yes | ||
43 | GADD45G | 2510142 | 2603 | 0.758 | 0.5345 | Yes | ||
44 | TLE3 | 580040 4730121 | 2669 | 0.728 | 0.5353 | Yes | ||
45 | CACNA1D | 1740315 4730731 | 2744 | 0.682 | 0.5353 | Yes | ||
46 | PSEN2 | 130382 | 2754 | 0.678 | 0.5388 | Yes | ||
47 | RAMP2 | 6860037 | 2783 | 0.667 | 0.5412 | Yes | ||
48 | PPARGC1B | 3290114 | 2786 | 0.666 | 0.5451 | Yes | ||
49 | CDC14A | 4050132 | 2817 | 0.652 | 0.5473 | Yes | ||
50 | B4GALT2 | 780037 | 3016 | 0.565 | 0.5399 | No | ||
51 | DUSP4 | 2690044 2850593 | 3047 | 0.555 | 0.5415 | No | ||
52 | UBE1 | 4150139 7050463 | 3061 | 0.550 | 0.5441 | No | ||
53 | RBBP6 | 2320129 | 3246 | 0.481 | 0.5370 | No | ||
54 | MAPKAPK3 | 630520 | 3289 | 0.462 | 0.5374 | No | ||
55 | TIMM9 | 2450484 | 3293 | 0.460 | 0.5400 | No | ||
56 | NR5A1 | 70707 | 3329 | 0.450 | 0.5407 | No | ||
57 | KCNK5 | 4590504 6860687 | 3524 | 0.383 | 0.5325 | No | ||
58 | RUNX2 | 1400193 4230215 | 3628 | 0.345 | 0.5289 | No | ||
59 | AMPD2 | 630093 1170070 | 3701 | 0.323 | 0.5269 | No | ||
60 | BAI2 | 380632 630113 6650170 | 3838 | 0.291 | 0.5213 | No | ||
61 | CTBP2 | 430309 3710079 | 3854 | 0.287 | 0.5221 | No | ||
62 | ARRDC3 | 4610390 | 4025 | 0.249 | 0.5144 | No | ||
63 | RAD9A | 110300 1940632 3990390 6040014 | 4030 | 0.247 | 0.5156 | No | ||
64 | PANK3 | 3060687 | 4043 | 0.245 | 0.5164 | No | ||
65 | TIAL1 | 4150048 6510605 | 4148 | 0.228 | 0.5121 | No | ||
66 | SOX12 | 1780037 | 4325 | 0.202 | 0.5038 | No | ||
67 | ADPRHL1 | 4150133 6650300 | 4472 | 0.182 | 0.4969 | No | ||
68 | RCL1 | 1980408 2680008 3800176 | 4516 | 0.178 | 0.4957 | No | ||
69 | SOCS5 | 3830398 7100093 | 4608 | 0.167 | 0.4917 | No | ||
70 | NR1D1 | 2360471 770746 6590204 | 5147 | 0.122 | 0.4633 | No | ||
71 | NRXN1 | 460408 5340270 6370066 | 5148 | 0.122 | 0.4640 | No | ||
72 | ANGPT2 | 1230458 5720706 6040605 | 5211 | 0.118 | 0.4613 | No | ||
73 | TESK2 | 6520524 | 5325 | 0.111 | 0.4558 | No | ||
74 | SEMA7A | 2630239 5050593 | 5594 | 0.097 | 0.4419 | No | ||
75 | GPC3 | 6180735 | 5646 | 0.095 | 0.4397 | No | ||
76 | HS3ST3A1 | 2230497 | 5988 | 0.079 | 0.4216 | No | ||
77 | XRN2 | 130603 1230113 4230309 | 5998 | 0.079 | 0.4216 | No | ||
78 | COL2A1 | 460446 3940500 | 6227 | 0.070 | 0.4097 | No | ||
79 | SC5DL | 6650390 | 6447 | 0.062 | 0.3982 | No | ||
80 | TPM2 | 520735 3870390 | 6715 | 0.054 | 0.3840 | No | ||
81 | NXPH1 | 3870546 | 6731 | 0.054 | 0.3835 | No | ||
82 | RTN4RL2 | 6450609 | 6876 | 0.050 | 0.3760 | No | ||
83 | SGTB | 460170 | 6886 | 0.050 | 0.3758 | No | ||
84 | EN2 | 7000368 | 6967 | 0.048 | 0.3717 | No | ||
85 | KIAA0427 | 1690435 | 7062 | 0.046 | 0.3669 | No | ||
86 | DNAJB9 | 460114 | 7132 | 0.044 | 0.3634 | No | ||
87 | ETV1 | 70735 2940603 5080463 | 7339 | 0.040 | 0.3525 | No | ||
88 | PLA2G4A | 6380364 | 7405 | 0.039 | 0.3492 | No | ||
89 | LIN28 | 6590672 | 7537 | 0.036 | 0.3423 | No | ||
90 | AKAP10 | 2630504 5910577 | 7636 | 0.034 | 0.3372 | No | ||
91 | SLC12A5 | 1980692 | 7692 | 0.033 | 0.3344 | No | ||
92 | DNMT3A | 4050068 4810717 | 7769 | 0.032 | 0.3305 | No | ||
93 | RNF128 | 1230300 5670273 | 7805 | 0.031 | 0.3288 | No | ||
94 | POGK | 5290315 | 7921 | 0.029 | 0.3227 | No | ||
95 | SLC38A5 | 540093 | 8146 | 0.025 | 0.3107 | No | ||
96 | HOXC13 | 4070722 | 8173 | 0.024 | 0.3094 | No | ||
97 | BMP2K | 60541 5570504 | 8196 | 0.024 | 0.3084 | No | ||
98 | NRAS | 6900577 | 8445 | 0.019 | 0.2950 | No | ||
99 | GRIN2A | 6550538 | 8547 | 0.018 | 0.2897 | No | ||
100 | NKX2-2 | 4150731 | 8814 | 0.013 | 0.2753 | No | ||
101 | FGF11 | 840292 | 8837 | 0.013 | 0.2742 | No | ||
102 | ADAM10 | 3780156 | 8844 | 0.013 | 0.2740 | No | ||
103 | PCDHA10 | 3830725 | 8973 | 0.011 | 0.2671 | No | ||
104 | B3GALT2 | 430136 | 9017 | 0.010 | 0.2648 | No | ||
105 | NUP153 | 7000452 | 9033 | 0.010 | 0.2640 | No | ||
106 | SLC17A2 | 870593 2810035 | 9150 | 0.008 | 0.2578 | No | ||
107 | CHRM1 | 4280619 | 9255 | 0.007 | 0.2522 | No | ||
108 | LAP3 | 2570064 | 9787 | -0.001 | 0.2234 | No | ||
109 | CTSF | 6100021 | 9893 | -0.003 | 0.2177 | No | ||
110 | MTHFD1 | 5900398 6520427 | 10575 | -0.013 | 0.1809 | No | ||
111 | ALX4 | 3870019 | 10659 | -0.014 | 0.1765 | No | ||
112 | GPS1 | 2470037 4760315 6200528 7100040 | 10663 | -0.014 | 0.1764 | No | ||
113 | STMN4 | 2900091 | 10730 | -0.015 | 0.1729 | No | ||
114 | LHX9 | 2350112 | 10874 | -0.018 | 0.1652 | No | ||
115 | ABCA1 | 6290156 | 10877 | -0.018 | 0.1652 | No | ||
116 | ENPP6 | 110524 580563 | 10945 | -0.019 | 0.1617 | No | ||
117 | BARHL1 | 4210113 | 11111 | -0.022 | 0.1529 | No | ||
118 | MAX | 5220021 | 11147 | -0.022 | 0.1511 | No | ||
119 | PRKCE | 5700053 | 11229 | -0.024 | 0.1469 | No | ||
120 | APOA5 | 6130471 | 11412 | -0.027 | 0.1372 | No | ||
121 | EIF3S1 | 6130368 6770044 | 11684 | -0.032 | 0.1227 | No | ||
122 | NEUROD2 | 5290097 | 11801 | -0.034 | 0.1166 | No | ||
123 | SEPT3 | 3830022 5290079 | 11812 | -0.035 | 0.1162 | No | ||
124 | HPCA | 6860010 | 11860 | -0.036 | 0.1139 | No | ||
125 | NPM1 | 4730427 | 11866 | -0.036 | 0.1138 | No | ||
126 | FLT3 | 2640487 | 12169 | -0.042 | 0.0977 | No | ||
127 | SFXN2 | 2650563 3140095 3830762 3870398 | 12373 | -0.047 | 0.0870 | No | ||
128 | NEUROD6 | 4670731 | 12501 | -0.050 | 0.0804 | No | ||
129 | SCFD2 | 2480504 | 12606 | -0.053 | 0.0750 | No | ||
130 | NDUFS1 | 2650253 | 12678 | -0.055 | 0.0715 | No | ||
131 | U2AF2 | 450600 4670128 5420292 | 12771 | -0.059 | 0.0669 | No | ||
132 | PLAG1 | 1450142 3870139 6520039 | 12927 | -0.064 | 0.0589 | No | ||
133 | IPO13 | 3870088 | 12934 | -0.064 | 0.0589 | No | ||
134 | WEE1 | 3390070 | 13037 | -0.067 | 0.0538 | No | ||
135 | POU3F1 | 3710022 | 13330 | -0.080 | 0.0384 | No | ||
136 | HHIP | 6940438 | 13401 | -0.083 | 0.0351 | No | ||
137 | ADAMTS17 | 6510739 | 13481 | -0.087 | 0.0313 | No | ||
138 | SNCAIP | 4010551 | 13535 | -0.089 | 0.0290 | No | ||
139 | CHST11 | 6760546 | 13550 | -0.090 | 0.0288 | No | ||
140 | PLAGL1 | 3190082 6200193 | 13641 | -0.095 | 0.0244 | No | ||
141 | ZZZ3 | 780133 2320239 2640452 5080706 6550341 | 13821 | -0.108 | 0.0154 | No | ||
142 | CUGBP1 | 450292 510022 7050176 7050215 | 13895 | -0.113 | 0.0121 | No | ||
143 | DLC1 | 1090632 6450594 | 13941 | -0.116 | 0.0103 | No | ||
144 | ZHX2 | 2900452 | 14331 | -0.152 | -0.0099 | No | ||
145 | JPH1 | 610739 | 14363 | -0.155 | -0.0106 | No | ||
146 | MCM8 | 6130743 | 14383 | -0.157 | -0.0108 | No | ||
147 | CLCN2 | 1940021 | 14501 | -0.169 | -0.0161 | No | ||
148 | RBM3 | 2360739 5700167 | 14537 | -0.172 | -0.0170 | No | ||
149 | HRH3 | 6180040 | 14551 | -0.173 | -0.0167 | No | ||
150 | HOXB7 | 4540706 4610358 | 14615 | -0.184 | -0.0190 | No | ||
151 | ADCY3 | 2350347 3440242 | 14667 | -0.190 | -0.0206 | No | ||
152 | RPL13A | 2680519 5700142 | 14763 | -0.207 | -0.0246 | No | ||
153 | RXRB | 1780040 5340438 | 15496 | -0.407 | -0.0619 | No | ||
154 | SEMA3F | 5420601 6770731 | 15618 | -0.458 | -0.0657 | No | ||
155 | TEF | 1050050 3120397 4060487 | 15768 | -0.529 | -0.0707 | No | ||
156 | SCYL1 | 5050717 | 15951 | -0.629 | -0.0768 | No | ||
157 | GRK6 | 1500053 | 16014 | -0.659 | -0.0763 | No | ||
158 | ATP6V0B | 2810112 | 16145 | -0.735 | -0.0790 | No | ||
159 | MNT | 4920575 | 16146 | -0.736 | -0.0747 | No | ||
160 | PFKFB3 | 630706 | 16270 | -0.815 | -0.0765 | No | ||
161 | MXD4 | 4810113 | 16347 | -0.865 | -0.0755 | No | ||
162 | HRSP12 | 610136 2510133 4280561 2760047 | 16418 | -0.907 | -0.0740 | No | ||
163 | HBP1 | 2510102 3130010 4210619 | 16575 | -1.003 | -0.0765 | No | ||
164 | TOP1 | 770471 4060632 6650324 | 16657 | -1.051 | -0.0747 | No | ||
165 | GNA13 | 4590102 | 16772 | -1.147 | -0.0741 | No | ||
166 | HTF9C | 3190048 4120132 | 16779 | -1.153 | -0.0676 | No | ||
167 | USP2 | 1190292 1240253 4850035 | 16789 | -1.162 | -0.0612 | No | ||
168 | PDK2 | 2690017 | 16814 | -1.184 | -0.0555 | No | ||
169 | BCL2 | 730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164 | 16927 | -1.270 | -0.0541 | No | ||
170 | GADD45B | 2350408 | 16943 | -1.289 | -0.0473 | No | ||
171 | ARF6 | 3520026 | 16977 | -1.316 | -0.0413 | No | ||
172 | PFN1 | 6130132 | 17292 | -1.714 | -0.0482 | No | ||
173 | SLC20A1 | 6420014 | 17320 | -1.735 | -0.0394 | No | ||
174 | AP1GBP1 | 2510372 | 17646 | -2.322 | -0.0433 | No | ||
175 | GJA1 | 5220731 | 18083 | -3.378 | -0.0470 | No | ||
176 | STAT3 | 460040 3710341 | 18169 | -3.701 | -0.0298 | No | ||
177 | RPIA | 780079 | 18223 | -3.944 | -0.0094 | No | ||
178 | WBP2 | 3170128 | 18414 | -5.182 | 0.0110 | No |