Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | V$NKX61_01 |
Enrichment Score (ES) | -0.5740564 |
Normalized Enrichment Score (NES) | -1.5237049 |
Nominal p-value | 0.0 |
FDR q-value | 0.11999257 |
FWER p-Value | 0.74 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | WNT8B | 4560301 | 661 | 2.596 | -0.0115 | No | ||
2 | LMNA | 520471 1500075 3190167 4210020 | 889 | 2.200 | -0.0032 | No | ||
3 | MBNL2 | 3450707 | 1087 | 1.929 | 0.0041 | No | ||
4 | CXCL13 | 6290402 | 1109 | 1.898 | 0.0208 | No | ||
5 | CUL3 | 1850520 | 1147 | 1.860 | 0.0362 | No | ||
6 | ATP2A2 | 1090075 3990279 | 1522 | 1.512 | 0.0301 | No | ||
7 | TYRO3 | 3130193 | 2400 | 0.878 | -0.0092 | No | ||
8 | NTNG2 | 1770438 6380408 | 2416 | 0.873 | -0.0019 | No | ||
9 | ZADH2 | 520438 | 2625 | 0.746 | -0.0062 | No | ||
10 | TCF4 | 520021 | 2646 | 0.737 | -0.0003 | No | ||
11 | DTNA | 1340600 1780731 2340278 2850132 | 2772 | 0.670 | -0.0008 | No | ||
12 | VAMP3 | 7100050 | 2790 | 0.663 | 0.0044 | No | ||
13 | STOML2 | 1940487 | 2880 | 0.626 | 0.0055 | No | ||
14 | PRKAG1 | 6450091 | 2965 | 0.588 | 0.0064 | No | ||
15 | CDC2L2 | 1400671 5290168 | 3108 | 0.534 | 0.0037 | No | ||
16 | HOXC6 | 3850133 4920736 | 3150 | 0.518 | 0.0064 | No | ||
17 | PLRG1 | 4480735 | 3265 | 0.474 | 0.0046 | No | ||
18 | TBXAS1 | 5050053 6900286 | 3321 | 0.452 | 0.0059 | No | ||
19 | RNF4 | 580286 1400152 | 3407 | 0.426 | 0.0053 | No | ||
20 | EN1 | 5360168 7050025 | 3485 | 0.400 | 0.0048 | No | ||
21 | NSD1 | 4560519 4780672 | 3497 | 0.394 | 0.0079 | No | ||
22 | AMMECR1 | 3800435 | 3506 | 0.392 | 0.0112 | No | ||
23 | SESN3 | 110687 | 3741 | 0.310 | 0.0014 | No | ||
24 | SSBP3 | 870717 1050377 7040551 | 3805 | 0.298 | 0.0008 | No | ||
25 | HESX1 | 4050746 | 3822 | 0.293 | 0.0026 | No | ||
26 | ERG | 50154 1770739 | 3890 | 0.277 | 0.0016 | No | ||
27 | NR2F1 | 4120528 360402 | 3939 | 0.267 | 0.0015 | No | ||
28 | NCOR1 | 3710132 | 3941 | 0.267 | 0.0039 | No | ||
29 | DSG4 | 3990605 6400736 | 3991 | 0.254 | 0.0037 | No | ||
30 | A2BP1 | 2370390 4590593 5550014 | 4173 | 0.223 | -0.0040 | No | ||
31 | AOC2 | 520348 3120008 | 4183 | 0.221 | -0.0025 | No | ||
32 | HABP2 | 5360541 6350273 | 4260 | 0.210 | -0.0046 | No | ||
33 | FOXP2 | 3520561 4150372 4760524 | 4450 | 0.185 | -0.0131 | No | ||
34 | MID1 | 4070114 4760458 | 4475 | 0.182 | -0.0127 | No | ||
35 | ERMAP | 780156 | 4682 | 0.160 | -0.0224 | No | ||
36 | ZRANB1 | 510373 4540278 | 4698 | 0.158 | -0.0217 | No | ||
37 | PDGFRA | 2940332 | 5000 | 0.131 | -0.0368 | No | ||
38 | UBE2C | 6130017 | 5106 | 0.125 | -0.0413 | No | ||
39 | OTP | 2630070 | 5120 | 0.124 | -0.0409 | No | ||
40 | ANGPT2 | 1230458 5720706 6040605 | 5211 | 0.118 | -0.0446 | No | ||
41 | PLCB1 | 2570050 7100102 | 5457 | 0.104 | -0.0569 | No | ||
42 | ANXA10 | 4050750 | 5641 | 0.095 | -0.0660 | No | ||
43 | SLITRK3 | 5910041 | 5708 | 0.092 | -0.0687 | No | ||
44 | HOXC4 | 1940193 | 5727 | 0.091 | -0.0688 | No | ||
45 | MYF6 | 2690576 | 5893 | 0.083 | -0.0770 | No | ||
46 | CLOCK | 1410070 2940292 3390075 | 5914 | 0.082 | -0.0773 | No | ||
47 | PPARGC1A | 4670040 | 5917 | 0.082 | -0.0766 | No | ||
48 | MAN1C1 | 730133 870398 2340044 | 6066 | 0.076 | -0.0839 | No | ||
49 | GAD2 | 1400088 | 6352 | 0.066 | -0.0988 | No | ||
50 | CHCHD7 | 6620692 | 6385 | 0.064 | -0.0999 | No | ||
51 | HOXB8 | 3710450 | 6420 | 0.063 | -0.1011 | No | ||
52 | PRRX1 | 4120193 4480390 | 6431 | 0.063 | -0.1011 | No | ||
53 | HOXC10 | 5360170 | 6559 | 0.059 | -0.1074 | No | ||
54 | USF2 | 3870368 5570348 6940039 | 6603 | 0.058 | -0.1092 | No | ||
55 | LMO1 | 3170528 | 6745 | 0.054 | -0.1163 | No | ||
56 | FGFR2 | 4670601 5570402 6940377 | 6882 | 0.050 | -0.1232 | No | ||
57 | NHLH2 | 6200021 | 6928 | 0.049 | -0.1252 | No | ||
58 | PURA | 3870156 | 7018 | 0.047 | -0.1296 | No | ||
59 | ODZ1 | 5050731 | 7097 | 0.045 | -0.1334 | No | ||
60 | PTPN22 | 1690647 7100239 | 7171 | 0.043 | -0.1369 | No | ||
61 | PHOX2B | 5270075 | 7210 | 0.043 | -0.1386 | No | ||
62 | SLC26A7 | 1850398 3830377 | 7298 | 0.041 | -0.1429 | No | ||
63 | EYA1 | 1450278 5220390 | 7321 | 0.040 | -0.1438 | No | ||
64 | ESRRG | 4010181 | 7424 | 0.038 | -0.1489 | No | ||
65 | SOX18 | 2320086 | 7475 | 0.037 | -0.1513 | No | ||
66 | ELP4 | 1230576 | 7796 | 0.031 | -0.1683 | No | ||
67 | SATB2 | 2470181 | 7951 | 0.028 | -0.1764 | No | ||
68 | IRX4 | 1980102 | 8260 | 0.023 | -0.1929 | No | ||
69 | NPR3 | 1580239 | 8413 | 0.020 | -0.2009 | No | ||
70 | RAB3C | 5420072 | 8425 | 0.020 | -0.2013 | No | ||
71 | NEUROG1 | 380341 | 8575 | 0.017 | -0.2092 | No | ||
72 | MYT1 | 6770524 | 8683 | 0.016 | -0.2149 | No | ||
73 | LGI1 | 1850020 | 8826 | 0.013 | -0.2225 | No | ||
74 | ZFPM2 | 460072 | 9001 | 0.010 | -0.2318 | No | ||
75 | SDPR | 3360292 | 9184 | 0.007 | -0.2416 | No | ||
76 | ELF4 | 4850193 | 9324 | 0.005 | -0.2491 | No | ||
77 | FGF7 | 5390484 | 9369 | 0.005 | -0.2514 | No | ||
78 | GNAT2 | 2450433 | 9411 | 0.004 | -0.2536 | No | ||
79 | LRRTM1 | 1690324 | 9434 | 0.004 | -0.2547 | No | ||
80 | BAI3 | 940692 | 9500 | 0.003 | -0.2582 | No | ||
81 | LHX6 | 2360731 3360397 | 9697 | -0.000 | -0.2689 | No | ||
82 | HOXD8 | 3710156 | 9722 | -0.000 | -0.2701 | No | ||
83 | C1QTNF7 | 2970619 | 9735 | -0.001 | -0.2708 | No | ||
84 | CDKL5 | 2450070 | 10141 | -0.006 | -0.2927 | No | ||
85 | FGF12 | 1740446 2360037 | 10149 | -0.007 | -0.2930 | No | ||
86 | HSD17B2 | 3800541 | 10223 | -0.008 | -0.2969 | No | ||
87 | BOC | 5270348 | 10258 | -0.008 | -0.2986 | No | ||
88 | P518 | 3610435 | 10467 | -0.011 | -0.3098 | No | ||
89 | ARX | 6900504 | 10560 | -0.013 | -0.3147 | No | ||
90 | ACMSD | 1450538 | 10652 | -0.014 | -0.3195 | No | ||
91 | HSN2 | 610180 | 10695 | -0.015 | -0.3216 | No | ||
92 | GABRB2 | 870059 | 10768 | -0.016 | -0.3254 | No | ||
93 | WNT7A | 1170315 | 10773 | -0.016 | -0.3254 | No | ||
94 | KCNIP2 | 60088 1780324 | 10849 | -0.017 | -0.3293 | No | ||
95 | PTPRD | 520008 3120097 | 10881 | -0.018 | -0.3308 | No | ||
96 | HOXA11 | 6980133 | 11193 | -0.023 | -0.3475 | No | ||
97 | MLSTD1 | 3710184 | 11215 | -0.023 | -0.3484 | No | ||
98 | NR4A3 | 2900021 5860095 5910039 | 11360 | -0.026 | -0.3559 | No | ||
99 | SLC6A15 | 5290176 6040017 | 11562 | -0.029 | -0.3666 | No | ||
100 | CREB5 | 2320368 | 11678 | -0.032 | -0.3725 | No | ||
101 | COL11A2 | 5130341 | 11706 | -0.032 | -0.3737 | No | ||
102 | TBX5 | 2900132 6370484 | 11750 | -0.033 | -0.3757 | No | ||
103 | KCNJ16 | 4780273 | 11756 | -0.033 | -0.3756 | No | ||
104 | NEUROD2 | 5290097 | 11801 | -0.034 | -0.3777 | No | ||
105 | RARB | 430139 1410138 | 12058 | -0.040 | -0.3912 | No | ||
106 | GK2 | 6510736 | 12180 | -0.043 | -0.3974 | No | ||
107 | CGA | 630403 | 12441 | -0.048 | -0.4110 | No | ||
108 | NEUROD6 | 4670731 | 12501 | -0.050 | -0.4137 | No | ||
109 | FUT11 | 6040692 | 12557 | -0.052 | -0.4162 | No | ||
110 | KLF15 | 4230164 | 12783 | -0.059 | -0.4278 | No | ||
111 | DMP1 | 4760398 | 12802 | -0.059 | -0.4283 | No | ||
112 | TCL1A | 3420367 | 12873 | -0.062 | -0.4315 | No | ||
113 | SV2A | 1450039 5570685 | 12880 | -0.062 | -0.4312 | No | ||
114 | RIMS2 | 670725 | 13122 | -0.071 | -0.4436 | No | ||
115 | ALDH1A2 | 2320301 | 13599 | -0.093 | -0.4685 | No | ||
116 | SLC6A4 | 2230372 | 13678 | -0.098 | -0.4718 | No | ||
117 | ITGA7 | 1230739 | 13987 | -0.120 | -0.4874 | No | ||
118 | PLCD4 | 6450040 | 14036 | -0.123 | -0.4889 | No | ||
119 | PRDM13 | 1430022 | 14096 | -0.128 | -0.4909 | No | ||
120 | POU3F4 | 870274 | 14322 | -0.151 | -0.5016 | No | ||
121 | SOX5 | 2370576 2900167 3190128 5050528 | 14330 | -0.152 | -0.5006 | No | ||
122 | PCSK2 | 360017 430528 5900619 | 14405 | -0.159 | -0.5031 | No | ||
123 | APOBEC2 | 1690520 | 14430 | -0.162 | -0.5029 | No | ||
124 | AP3M2 | 6370474 | 14601 | -0.181 | -0.5104 | No | ||
125 | RHOBTB3 | 4010687 | 14969 | -0.252 | -0.5279 | No | ||
126 | MDGA1 | 1170139 | 15106 | -0.280 | -0.5327 | No | ||
127 | FHL1 | 60278 | 15358 | -0.356 | -0.5429 | No | ||
128 | MYO10 | 3830576 5570092 | 15410 | -0.372 | -0.5422 | No | ||
129 | ZIC4 | 1500082 | 15724 | -0.510 | -0.5544 | No | ||
130 | SLC12A6 | 610278 1980035 5340671 | 15763 | -0.528 | -0.5515 | No | ||
131 | PPP3CB | 6020156 | 15807 | -0.545 | -0.5488 | No | ||
132 | RAB5B | 130397 1980273 6900731 | 16275 | -0.819 | -0.5664 | Yes | ||
133 | KLHL5 | 3060484 6400292 | 16330 | -0.856 | -0.5613 | Yes | ||
134 | MARCKS | 7040450 | 16376 | -0.885 | -0.5555 | Yes | ||
135 | FLI1 | 3990142 | 16561 | -0.999 | -0.5561 | Yes | ||
136 | ZFP36L1 | 2510138 4120048 | 16675 | -1.064 | -0.5522 | Yes | ||
137 | LARGE | 6940068 | 16743 | -1.118 | -0.5454 | Yes | ||
138 | FOXP3 | 940707 1850692 | 16933 | -1.277 | -0.5437 | Yes | ||
139 | SOX4 | 2260091 | 17066 | -1.434 | -0.5374 | Yes | ||
140 | KCNN3 | 6520600 6420138 | 17130 | -1.518 | -0.5266 | Yes | ||
141 | CHD2 | 4070039 | 17205 | -1.609 | -0.5156 | Yes | ||
142 | SLC20A1 | 6420014 | 17320 | -1.735 | -0.5055 | Yes | ||
143 | NDUFA4 | 6860364 | 17373 | -1.824 | -0.4913 | Yes | ||
144 | HNRPA0 | 2680048 | 17431 | -1.910 | -0.4765 | Yes | ||
145 | RPA3 | 5700136 | 17721 | -2.461 | -0.4691 | Yes | ||
146 | TRIM8 | 6130441 | 17757 | -2.538 | -0.4472 | Yes | ||
147 | GATA3 | 6130068 | 17768 | -2.566 | -0.4238 | Yes | ||
148 | ARID5A | 2450133 | 17979 | -3.029 | -0.4068 | Yes | ||
149 | HOXA7 | 5910152 | 18010 | -3.106 | -0.3794 | Yes | ||
150 | DUSP6 | 5910286 7100070 | 18031 | -3.173 | -0.3508 | Yes | ||
151 | TOB1 | 4150138 | 18066 | -3.318 | -0.3215 | Yes | ||
152 | CLK2 | 510079 2630736 | 18091 | -3.402 | -0.2910 | Yes | ||
153 | TLE4 | 1450064 1500519 | 18134 | -3.567 | -0.2599 | Yes | ||
154 | SH3BGRL3 | 1850750 | 18381 | -4.889 | -0.2275 | Yes | ||
155 | BCL6 | 940100 | 18397 | -5.006 | -0.1814 | Yes | ||
156 | HSD11B1 | 450066 5550408 | 18421 | -5.285 | -0.1332 | Yes | ||
157 | ETS2 | 360451 | 18547 | -6.975 | -0.0747 | Yes | ||
158 | CCND2 | 5340167 | 18589 | -8.378 | 0.0015 | Yes |