Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | wtNotch |
GeneSet | V$MAX_01 |
Enrichment Score (ES) | 0.4218957 |
Normalized Enrichment Score (NES) | 1.18018 |
Nominal p-value | 0.088541664 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | TIMM10 | 610070 1450019 | 3 | 9.579 | 0.0472 | Yes | ||
2 | AKAP12 | 1450739 | 58 | 5.480 | 0.0713 | Yes | ||
3 | BAX | 3830008 | 85 | 4.907 | 0.0941 | Yes | ||
4 | AATF | 5220575 | 123 | 4.556 | 0.1146 | Yes | ||
5 | VPS16 | 430064 3390041 6860301 | 148 | 4.381 | 0.1350 | Yes | ||
6 | PA2G4 | 2030463 | 194 | 4.069 | 0.1527 | Yes | ||
7 | NOTCH1 | 3390114 | 308 | 3.576 | 0.1642 | Yes | ||
8 | PFDN2 | 4230156 | 348 | 3.411 | 0.1789 | Yes | ||
9 | CAD | 2340717 | 350 | 3.407 | 0.1957 | Yes | ||
10 | SUPT16H | 1240333 | 357 | 3.397 | 0.2122 | Yes | ||
11 | ACY1 | 2360279 6550161 | 390 | 3.268 | 0.2266 | Yes | ||
12 | NUDC | 4780025 | 395 | 3.235 | 0.2423 | Yes | ||
13 | HMGA1 | 6580408 | 406 | 3.191 | 0.2576 | Yes | ||
14 | HNRPA1 | 4670398 5050687 | 481 | 2.980 | 0.2683 | Yes | ||
15 | OPRS1 | 6130128 6290717 | 496 | 2.961 | 0.2822 | Yes | ||
16 | CFL1 | 2340735 | 498 | 2.954 | 0.2967 | Yes | ||
17 | MRPL27 | 2060131 | 609 | 2.682 | 0.3040 | Yes | ||
18 | PTGES2 | 4210097 | 630 | 2.650 | 0.3160 | Yes | ||
19 | EIF4B | 5390563 5270577 | 653 | 2.610 | 0.3277 | Yes | ||
20 | PPRC1 | 1740441 | 668 | 2.584 | 0.3397 | Yes | ||
21 | DDX3X | 2190020 | 681 | 2.564 | 0.3517 | Yes | ||
22 | PSME3 | 2810537 | 703 | 2.529 | 0.3631 | Yes | ||
23 | EIF2C2 | 770451 | 739 | 2.467 | 0.3734 | Yes | ||
24 | QTRT1 | 1340162 | 834 | 2.291 | 0.3796 | Yes | ||
25 | ASNA1 | 3830041 | 845 | 2.268 | 0.3902 | Yes | ||
26 | CCAR1 | 3190092 | 861 | 2.243 | 0.4005 | Yes | ||
27 | FKBP11 | 3170575 | 979 | 2.067 | 0.4044 | Yes | ||
28 | EEF1B2 | 4850400 6130161 | 1078 | 1.937 | 0.4086 | Yes | ||
29 | TIMM8A | 110279 | 1095 | 1.918 | 0.4173 | Yes | ||
30 | SRP72 | 3990427 | 1241 | 1.774 | 0.4182 | Yes | ||
31 | ZCCHC7 | 6510592 | 1453 | 1.582 | 0.4145 | Yes | ||
32 | TFRC | 4050551 | 1557 | 1.475 | 0.4162 | Yes | ||
33 | ATF4 | 730441 1740195 | 1631 | 1.410 | 0.4193 | Yes | ||
34 | PRPS1 | 6350129 | 1706 | 1.347 | 0.4219 | Yes | ||
35 | PLCG2 | 5720008 | 1843 | 1.237 | 0.4206 | No | ||
36 | CLN3 | 780368 | 2053 | 1.063 | 0.4146 | No | ||
37 | TAF6L | 1850056 | 2149 | 1.008 | 0.4144 | No | ||
38 | PABPC1 | 2650180 2690253 6020632 1990270 | 2171 | 1.000 | 0.4182 | No | ||
39 | HIRA | 4480609 5270167 | 2572 | 0.775 | 0.4003 | No | ||
40 | TCF4 | 520021 | 2646 | 0.737 | 0.4000 | No | ||
41 | ATP6V1C1 | 2690324 5220528 | 2680 | 0.719 | 0.4018 | No | ||
42 | STMN1 | 1990717 | 2698 | 0.711 | 0.4044 | No | ||
43 | RPS2 | 1340647 | 2710 | 0.706 | 0.4073 | No | ||
44 | GTF2H1 | 2570746 2650148 | 2773 | 0.670 | 0.4072 | No | ||
45 | COPZ1 | 6940100 | 2938 | 0.598 | 0.4013 | No | ||
46 | ATP6V1A | 6590242 | 2949 | 0.593 | 0.4037 | No | ||
47 | CD164 | 3830594 | 2993 | 0.577 | 0.4042 | No | ||
48 | UBE4B | 780008 3610154 | 3013 | 0.566 | 0.4060 | No | ||
49 | TCOF1 | 2680086 | 3041 | 0.557 | 0.4073 | No | ||
50 | SNTB2 | 2630014 5390035 | 3082 | 0.545 | 0.4078 | No | ||
51 | DHX35 | 1230440 | 3226 | 0.491 | 0.4025 | No | ||
52 | TOPORS | 4060592 | 3313 | 0.454 | 0.4000 | No | ||
53 | EN1 | 5360168 7050025 | 3485 | 0.400 | 0.3927 | No | ||
54 | QTRTD1 | 7000053 | 3594 | 0.359 | 0.3887 | No | ||
55 | RUNX2 | 1400193 4230215 | 3628 | 0.345 | 0.3886 | No | ||
56 | AMPD2 | 630093 1170070 | 3701 | 0.323 | 0.3863 | No | ||
57 | COMMD3 | 2510259 | 3862 | 0.285 | 0.3790 | No | ||
58 | SLC26A2 | 2360278 | 3949 | 0.265 | 0.3756 | No | ||
59 | SYT3 | 6380017 | 3959 | 0.262 | 0.3764 | No | ||
60 | UBXD3 | 5050193 | 4242 | 0.212 | 0.3622 | No | ||
61 | SUCLG2 | 5340397 5700270 | 4269 | 0.208 | 0.3618 | No | ||
62 | PPP1R3C | 2640170 | 4314 | 0.202 | 0.3604 | No | ||
63 | RCL1 | 1980408 2680008 3800176 | 4516 | 0.178 | 0.3504 | No | ||
64 | RAB3IL1 | 380685 5420176 | 4532 | 0.176 | 0.3505 | No | ||
65 | ARMET | 5130670 | 4547 | 0.174 | 0.3506 | No | ||
66 | ZNF318 | 5890091 6130021 | 4848 | 0.145 | 0.3350 | No | ||
67 | RAI14 | 770288 1660075 | 5020 | 0.130 | 0.3264 | No | ||
68 | CHD4 | 5420059 6130338 6380717 | 5129 | 0.123 | 0.3212 | No | ||
69 | NEUROD1 | 3060619 | 5284 | 0.114 | 0.3134 | No | ||
70 | TESK2 | 6520524 | 5325 | 0.111 | 0.3118 | No | ||
71 | DSCAM | 1780050 2450731 2810438 | 5471 | 0.103 | 0.3044 | No | ||
72 | GATA5 | 430465 | 5738 | 0.090 | 0.2904 | No | ||
73 | PICALM | 1940280 | 6457 | 0.062 | 0.2518 | No | ||
74 | IRS4 | 430341 1190450 | 6547 | 0.059 | 0.2473 | No | ||
75 | SLC1A7 | 1990181 | 6693 | 0.055 | 0.2397 | No | ||
76 | GUCY1A2 | 1660441 | 6878 | 0.050 | 0.2300 | No | ||
77 | EIF3S10 | 1190079 3840176 | 6975 | 0.048 | 0.2250 | No | ||
78 | FGF14 | 2630390 3520075 6770048 | 7005 | 0.048 | 0.2237 | No | ||
79 | DUSP7 | 2940309 | 7054 | 0.046 | 0.2213 | No | ||
80 | USP15 | 610592 3520504 | 7252 | 0.042 | 0.2108 | No | ||
81 | ETV1 | 70735 2940603 5080463 | 7339 | 0.040 | 0.2064 | No | ||
82 | LIN28 | 6590672 | 7537 | 0.036 | 0.1959 | No | ||
83 | DNMT3A | 4050068 4810717 | 7769 | 0.032 | 0.1835 | No | ||
84 | POGK | 5290315 | 7921 | 0.029 | 0.1755 | No | ||
85 | SLC38A5 | 540093 | 8146 | 0.025 | 0.1634 | No | ||
86 | XPO1 | 540707 | 8282 | 0.022 | 0.1562 | No | ||
87 | HOXD10 | 6100039 | 8626 | 0.016 | 0.1377 | No | ||
88 | ZBTB10 | 4200132 | 8659 | 0.016 | 0.1361 | No | ||
89 | HOXC5 | 1580017 | 8914 | 0.012 | 0.1223 | No | ||
90 | PCDHA10 | 3830725 | 8973 | 0.011 | 0.1193 | No | ||
91 | ODC1 | 5670168 | 9071 | 0.009 | 0.1140 | No | ||
92 | SSR1 | 5890100 | 9105 | 0.009 | 0.1123 | No | ||
93 | AKAP1 | 110148 1740735 2260019 7000563 | 9166 | 0.008 | 0.1091 | No | ||
94 | AP1S2 | 780279 4280707 | 9353 | 0.005 | 0.0990 | No | ||
95 | MEOX2 | 6400288 | 9396 | 0.005 | 0.0968 | No | ||
96 | SNX5 | 1570021 6860609 | 9426 | 0.004 | 0.0952 | No | ||
97 | BMP6 | 2100128 | 9746 | -0.001 | 0.0779 | No | ||
98 | LZTFL1 | 540114 | 9976 | -0.004 | 0.0655 | No | ||
99 | SIRT1 | 1190731 | 10156 | -0.007 | 0.0559 | No | ||
100 | NFX1 | 450504 | 10522 | -0.012 | 0.0361 | No | ||
101 | MTHFD1 | 5900398 6520427 | 10575 | -0.013 | 0.0334 | No | ||
102 | OPRD1 | 4280138 | 11066 | -0.021 | 0.0069 | No | ||
103 | MAX | 5220021 | 11147 | -0.022 | 0.0027 | No | ||
104 | HOXA11 | 6980133 | 11193 | -0.023 | 0.0004 | No | ||
105 | NRIP3 | 1340372 | 11336 | -0.025 | -0.0072 | No | ||
106 | FOXD3 | 6550156 | 11359 | -0.026 | -0.0083 | No | ||
107 | CPT1A | 6350093 | 11402 | -0.027 | -0.0104 | No | ||
108 | BCOR | 1660452 3940053 | 11428 | -0.027 | -0.0116 | No | ||
109 | SEPT3 | 3830022 5290079 | 11812 | -0.035 | -0.0322 | No | ||
110 | NPM1 | 4730427 | 11866 | -0.036 | -0.0349 | No | ||
111 | SYNCRIP | 1690195 3140113 4670279 | 12153 | -0.042 | -0.0502 | No | ||
112 | ATOH8 | 4540204 | 12385 | -0.047 | -0.0625 | No | ||
113 | HOXB5 | 2900538 | 12496 | -0.050 | -0.0682 | No | ||
114 | NDUFS1 | 2650253 | 12678 | -0.055 | -0.0778 | No | ||
115 | ELAVL3 | 2850014 | 12776 | -0.059 | -0.0827 | No | ||
116 | IPO13 | 3870088 | 12934 | -0.064 | -0.0909 | No | ||
117 | UBE2B | 4780497 | 13329 | -0.080 | -0.1119 | No | ||
118 | NPTX1 | 3710736 | 13357 | -0.081 | -0.1129 | No | ||
119 | ADAMTS17 | 6510739 | 13481 | -0.087 | -0.1192 | No | ||
120 | CBX5 | 3830072 6290167 | 13506 | -0.088 | -0.1200 | No | ||
121 | SNCAIP | 4010551 | 13535 | -0.089 | -0.1211 | No | ||
122 | TCERG1 | 2350551 4540397 5220746 | 13564 | -0.091 | -0.1222 | No | ||
123 | SUMF1 | 730050 | 13650 | -0.096 | -0.1263 | No | ||
124 | ANAPC13 | 3800446 | 13865 | -0.111 | -0.1374 | No | ||
125 | TGFB2 | 4920292 | 14066 | -0.126 | -0.1476 | No | ||
126 | GGN | 1410528 4210082 5290170 | 14373 | -0.156 | -0.1634 | No | ||
127 | HOXB7 | 4540706 4610358 | 14615 | -0.184 | -0.1756 | No | ||
128 | SLC38A2 | 1470242 3800026 | 14744 | -0.203 | -0.1815 | No | ||
129 | PER1 | 3290315 | 14765 | -0.207 | -0.1816 | No | ||
130 | KCNE4 | 2470102 | 15005 | -0.259 | -0.1932 | No | ||
131 | DVL2 | 6110162 | 15060 | -0.270 | -0.1948 | No | ||
132 | ILF3 | 940722 3190647 6520110 | 15079 | -0.275 | -0.1945 | No | ||
133 | PTMA | 5570148 | 15281 | -0.334 | -0.2037 | No | ||
134 | SLC31A2 | 1450577 | 15516 | -0.417 | -0.2143 | No | ||
135 | MRPL40 | 2370215 | 15517 | -0.417 | -0.2123 | No | ||
136 | GNB2 | 2350053 | 15840 | -0.561 | -0.2269 | No | ||
137 | BOK | 1170373 5860446 | 16068 | -0.692 | -0.2358 | No | ||
138 | MAT2A | 4070026 4730079 6020280 | 16267 | -0.813 | -0.2425 | No | ||
139 | MXD4 | 4810113 | 16347 | -0.865 | -0.2426 | No | ||
140 | EIF4E | 1580403 70133 6380215 | 16348 | -0.866 | -0.2383 | No | ||
141 | FEN1 | 1770541 | 16358 | -0.876 | -0.2344 | No | ||
142 | CSK | 6350593 | 16555 | -0.997 | -0.2401 | No | ||
143 | GNAS | 630441 1850373 4050152 | 16556 | -0.998 | -0.2352 | No | ||
144 | HBP1 | 2510102 3130010 4210619 | 16575 | -1.003 | -0.2312 | No | ||
145 | TOP1 | 770471 4060632 6650324 | 16657 | -1.051 | -0.2304 | No | ||
146 | EPC1 | 1570050 5290095 6900193 | 16678 | -1.065 | -0.2262 | No | ||
147 | CENTB5 | 5690128 | 16710 | -1.093 | -0.2225 | No | ||
148 | SMAD2 | 4200592 | 16721 | -1.104 | -0.2176 | No | ||
149 | HHEX | 2340575 | 16771 | -1.146 | -0.2146 | No | ||
150 | GPX1 | 4150093 | 16775 | -1.150 | -0.2091 | No | ||
151 | ALDH6A1 | 1770746 | 16795 | -1.165 | -0.2044 | No | ||
152 | PDK2 | 2690017 | 16814 | -1.184 | -0.1995 | No | ||
153 | MTCH2 | 3780603 6620215 | 16826 | -1.189 | -0.1942 | No | ||
154 | PRKCH | 5720079 | 16926 | -1.270 | -0.1933 | No | ||
155 | PPM1A | 1170301 5900273 | 17215 | -1.615 | -0.2009 | No | ||
156 | LAMP1 | 2470524 | 17394 | -1.859 | -0.2014 | No | ||
157 | ATF7IP | 2690176 6770021 | 17420 | -1.898 | -0.1934 | No | ||
158 | BCAS3 | 4050647 | 17532 | -2.092 | -0.1891 | No | ||
159 | LZTS2 | 2260440 | 17730 | -2.476 | -0.1875 | No | ||
160 | BRDT | 3940102 | 17763 | -2.553 | -0.1766 | No | ||
161 | DNAJB5 | 2900215 | 17996 | -3.071 | -0.1740 | No | ||
162 | HOXA7 | 5910152 | 18010 | -3.106 | -0.1594 | No | ||
163 | GJA1 | 5220731 | 18083 | -3.378 | -0.1466 | No | ||
164 | ZFYVE26 | 6860152 | 18236 | -4.044 | -0.1349 | No | ||
165 | KBTBD2 | 2320014 | 18252 | -4.125 | -0.1153 | No | ||
166 | DUSP1 | 6860121 | 18476 | -5.793 | -0.0988 | No | ||
167 | ISGF3G | 3190131 7100142 | 18484 | -5.896 | -0.0700 | No | ||
168 | CDK5R1 | 3870161 | 18529 | -6.586 | -0.0399 | No | ||
169 | NIT1 | 1230338 3940671 | 18607 | -9.013 | 0.0005 | No |