Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | wtNotch |
GeneSet | V$LEF1_Q2 |
Enrichment Score (ES) | 0.40903386 |
Normalized Enrichment Score (NES) | 1.139354 |
Nominal p-value | 0.14357683 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | TIMM10 | 610070 1450019 | 3 | 9.579 | 0.0805 | Yes | ||
2 | SYTL1 | 510487 | 68 | 5.259 | 0.1213 | Yes | ||
3 | SMYD2 | 5050026 | 132 | 4.502 | 0.1558 | Yes | ||
4 | DHCR24 | 840600 1050672 6290097 | 409 | 3.188 | 0.1678 | Yes | ||
5 | SLC6A9 | 2470520 | 426 | 3.130 | 0.1932 | Yes | ||
6 | ARID1A | 2630022 1690551 4810110 | 474 | 2.995 | 0.2159 | Yes | ||
7 | CD160 | 4210377 | 532 | 2.850 | 0.2368 | Yes | ||
8 | CNR2 | 2760398 | 600 | 2.694 | 0.2559 | Yes | ||
9 | DYRK3 | 1090014 | 638 | 2.638 | 0.2761 | Yes | ||
10 | WNT8B | 4560301 | 661 | 2.596 | 0.2968 | Yes | ||
11 | ELOVL1 | 2450019 4760138 5340685 | 729 | 2.477 | 0.3140 | Yes | ||
12 | SYT13 | 5910110 | 824 | 2.318 | 0.3285 | Yes | ||
13 | PRKRIR | 2370402 | 843 | 2.275 | 0.3466 | Yes | ||
14 | GLUD1 | 4210372 | 868 | 2.232 | 0.3641 | Yes | ||
15 | RRM1 | 4150433 | 959 | 2.087 | 0.3768 | Yes | ||
16 | RPA2 | 2760301 5420195 | 1149 | 1.859 | 0.3823 | Yes | ||
17 | BMI1 | 3830026 2630204 | 1227 | 1.785 | 0.3931 | Yes | ||
18 | SDHC | 3140347 6100156 | 1280 | 1.732 | 0.4049 | Yes | ||
19 | SEMA4G | 5890026 | 1475 | 1.556 | 0.4075 | Yes | ||
20 | AHCYL1 | 540609 | 1663 | 1.382 | 0.4090 | Yes | ||
21 | YARS | 70739 | 2128 | 1.018 | 0.3925 | No | ||
22 | EFNA4 | 4280309 6550576 | 2330 | 0.924 | 0.3894 | No | ||
23 | NDUFS3 | 1690136 5340528 | 2678 | 0.720 | 0.3767 | No | ||
24 | NDUFC2 | 580075 | 2760 | 0.674 | 0.3780 | No | ||
25 | NCDN | 50040 1980739 3520603 | 2900 | 0.618 | 0.3756 | No | ||
26 | RUNX3 | 3800546 | 2976 | 0.583 | 0.3765 | No | ||
27 | UBE4B | 780008 3610154 | 3013 | 0.566 | 0.3793 | No | ||
28 | BSCL2 | 2680671 | 3277 | 0.467 | 0.3690 | No | ||
29 | TRIM33 | 580619 2230280 3990433 6200747 | 3348 | 0.446 | 0.3690 | No | ||
30 | PDC | 3140400 3780184 | 3496 | 0.395 | 0.3643 | No | ||
31 | SLC25A28 | 6590600 | 3515 | 0.387 | 0.3666 | No | ||
32 | RNF11 | 3990068 5080458 | 3636 | 0.342 | 0.3630 | No | ||
33 | AMPD3 | 610369 3360528 | 3688 | 0.326 | 0.3630 | No | ||
34 | MOV10 | 50673 430577 3870280 | 3706 | 0.322 | 0.3648 | No | ||
35 | BAI2 | 380632 630113 6650170 | 3838 | 0.291 | 0.3602 | No | ||
36 | DUSP10 | 2850673 3360064 | 4094 | 0.235 | 0.3483 | No | ||
37 | MMP21 | 4480673 | 4138 | 0.229 | 0.3479 | No | ||
38 | TIAL1 | 4150048 6510605 | 4148 | 0.228 | 0.3494 | No | ||
39 | HABP2 | 5360541 6350273 | 4260 | 0.210 | 0.3451 | No | ||
40 | TMEM9 | 130039 | 4368 | 0.196 | 0.3410 | No | ||
41 | SOX6 | 2940458 4070601 6840717 | 4371 | 0.196 | 0.3425 | No | ||
42 | EIF4G2 | 3800575 6860184 | 4422 | 0.188 | 0.3414 | No | ||
43 | DDR2 | 7050273 | 4474 | 0.182 | 0.3402 | No | ||
44 | HNRPR | 2320440 2900601 4610008 | 4708 | 0.157 | 0.3289 | No | ||
45 | SCUBE2 | 2850315 5130040 | 4788 | 0.150 | 0.3259 | No | ||
46 | GRK5 | 1940348 4670053 | 4902 | 0.140 | 0.3209 | No | ||
47 | COL13A1 | 4120079 | 4937 | 0.137 | 0.3202 | No | ||
48 | ELF5 | 3140156 5220020 | 5077 | 0.127 | 0.3138 | No | ||
49 | RERE | 3940279 | 5157 | 0.122 | 0.3105 | No | ||
50 | VAX1 | 6660750 | 5204 | 0.118 | 0.3090 | No | ||
51 | CLCNKA | 1740050 | 5491 | 0.102 | 0.2944 | No | ||
52 | PTCH2 | 2900092 | 5669 | 0.093 | 0.2856 | No | ||
53 | RGL1 | 1500097 6900450 | 5803 | 0.086 | 0.2791 | No | ||
54 | CACNB2 | 1500095 7330707 | 5847 | 0.085 | 0.2775 | No | ||
55 | MRVI1 | 4810338 4850601 5900441 | 6342 | 0.066 | 0.2513 | No | ||
56 | MPZ | 1990333 | 6412 | 0.064 | 0.2481 | No | ||
57 | PRRX1 | 4120193 4480390 | 6431 | 0.063 | 0.2477 | No | ||
58 | DKK1 | 1940215 | 6464 | 0.062 | 0.2465 | No | ||
59 | MFN2 | 2260195 6100164 | 6480 | 0.061 | 0.2462 | No | ||
60 | ANK3 | 1500161 2900435 4210154 6400100 | 6654 | 0.056 | 0.2373 | No | ||
61 | LMO1 | 3170528 | 6745 | 0.054 | 0.2329 | No | ||
62 | HIAT1 | 1580176 | 6820 | 0.052 | 0.2293 | No | ||
63 | PTPRJ | 4010707 | 6828 | 0.051 | 0.2294 | No | ||
64 | NEUROG3 | 6980451 | 6917 | 0.050 | 0.2250 | No | ||
65 | SORCS1 | 60411 5890373 | 6924 | 0.049 | 0.2251 | No | ||
66 | NHLH2 | 6200021 | 6928 | 0.049 | 0.2254 | No | ||
67 | PLA2G4A | 6380364 | 7405 | 0.039 | 0.1999 | No | ||
68 | ESRRG | 4010181 | 7424 | 0.038 | 0.1993 | No | ||
69 | PHTF1 | 7050441 | 7514 | 0.037 | 0.1948 | No | ||
70 | LIN28 | 6590672 | 7537 | 0.036 | 0.1939 | No | ||
71 | IL20 | 4850647 | 7919 | 0.029 | 0.1735 | No | ||
72 | SH2D4B | 670204 | 8156 | 0.024 | 0.1609 | No | ||
73 | PVRL4 | 2340048 6220195 | 8328 | 0.022 | 0.1518 | No | ||
74 | TCERG1L | 3360707 | 8357 | 0.021 | 0.1505 | No | ||
75 | RCN1 | 2480041 | 8399 | 0.020 | 0.1485 | No | ||
76 | DPYD | 6110095 | 8473 | 0.019 | 0.1447 | No | ||
77 | SLC17A6 | 4210576 | 8476 | 0.019 | 0.1447 | No | ||
78 | TLL2 | 6220040 | 8517 | 0.018 | 0.1427 | No | ||
79 | CGN | 5890139 6370167 6400537 | 8549 | 0.018 | 0.1412 | No | ||
80 | IL19 | 6040142 | 8759 | 0.014 | 0.1300 | No | ||
81 | CUBN | 630338 | 8772 | 0.014 | 0.1294 | No | ||
82 | AP4B1 | 2900300 | 8839 | 0.013 | 0.1260 | No | ||
83 | SPOCK2 | 6650369 | 9521 | 0.003 | 0.0891 | No | ||
84 | GAB2 | 1410280 2340520 4280040 | 9538 | 0.002 | 0.0883 | No | ||
85 | LRP8 | 3610746 5360035 | 9894 | -0.003 | 0.0691 | No | ||
86 | GNG3 | 6980397 | 10099 | -0.006 | 0.0581 | No | ||
87 | NEXN | 1240017 5290047 | 10120 | -0.006 | 0.0571 | No | ||
88 | SLC22A8 | 3520204 | 10161 | -0.007 | 0.0550 | No | ||
89 | SERPINC1 | 1780717 | 10450 | -0.011 | 0.0395 | No | ||
90 | UBE2D1 | 1850400 | 10642 | -0.014 | 0.0292 | No | ||
91 | LRRTM3 | 4210021 | 11341 | -0.025 | -0.0083 | No | ||
92 | COL11A1 | 2100300 2810136 4200706 4810524 | 11443 | -0.027 | -0.0136 | No | ||
93 | PAX6 | 1190025 | 11552 | -0.029 | -0.0192 | No | ||
94 | LPHN2 | 4480010 | 11655 | -0.031 | -0.0244 | No | ||
95 | PROX1 | 4210193 | 11978 | -0.038 | -0.0415 | No | ||
96 | SFXN2 | 2650563 3140095 3830762 3870398 | 12373 | -0.047 | -0.0625 | No | ||
97 | NEK7 | 4540026 | 12729 | -0.057 | -0.0812 | No | ||
98 | BSND | 1780041 | 12748 | -0.057 | -0.0817 | No | ||
99 | SV2A | 1450039 5570685 | 12880 | -0.062 | -0.0883 | No | ||
100 | ASB13 | 1090070 | 12911 | -0.063 | -0.0894 | No | ||
101 | ZFYVE9 | 6980288 7100017 | 13178 | -0.073 | -0.1032 | No | ||
102 | PAK1 | 4540315 | 13219 | -0.075 | -0.1047 | No | ||
103 | RET | 3850746 | 13225 | -0.075 | -0.1043 | No | ||
104 | WNT9A | 3830711 | 13249 | -0.076 | -0.1049 | No | ||
105 | EPHA2 | 5890056 | 13432 | -0.085 | -0.1141 | No | ||
106 | KBTBD4 | 70465 3840093 | 13504 | -0.088 | -0.1172 | No | ||
107 | LHX4 | 6940551 | 13648 | -0.096 | -0.1241 | No | ||
108 | LEMD1 | 3990132 5720187 | 13774 | -0.105 | -0.1300 | No | ||
109 | NPPA | 6550328 | 13815 | -0.107 | -0.1313 | No | ||
110 | DGAT2 | 5130685 | 13923 | -0.115 | -0.1361 | No | ||
111 | OVOL1 | 1690131 | 13948 | -0.117 | -0.1364 | No | ||
112 | SLC26A9 | 3440722 5340088 7510093 | 14257 | -0.144 | -0.1519 | No | ||
113 | NAV1 | 4210519 6620129 | 14351 | -0.154 | -0.1556 | No | ||
114 | CYP2E1 | 4480209 | 14387 | -0.157 | -0.1562 | No | ||
115 | ARNT | 1170672 5670711 | 14444 | -0.163 | -0.1578 | No | ||
116 | DCLRE1B | 540070 4730373 5550176 | 15126 | -0.284 | -0.1923 | No | ||
117 | ADAM12 | 3390132 4070347 | 15240 | -0.322 | -0.1957 | No | ||
118 | UAP1 | 3060093 | 15514 | -0.416 | -0.2070 | No | ||
119 | SLC16A9 | 6220497 | 15589 | -0.446 | -0.2072 | No | ||
120 | GFRA1 | 3610152 | 15614 | -0.454 | -0.2047 | No | ||
121 | ENTPD7 | 1980601 | 15673 | -0.485 | -0.2037 | No | ||
122 | CNTF | 450128 870253 1780068 6520195 | 15720 | -0.509 | -0.2020 | No | ||
123 | ELAVL4 | 50735 3360086 5220167 | 15928 | -0.615 | -0.2080 | No | ||
124 | SLC43A3 | 430168 5220400 | 16005 | -0.654 | -0.2066 | No | ||
125 | S100A3 | 6400563 | 16025 | -0.665 | -0.2020 | No | ||
126 | TCF7L2 | 2190348 5220113 | 16064 | -0.689 | -0.1983 | No | ||
127 | ACTR1A | 5860070 | 16080 | -0.697 | -0.1932 | No | ||
128 | FRAG1 | 1050504 1170152 2030092 | 16098 | -0.710 | -0.1881 | No | ||
129 | UCP2 | 2190050 4070711 | 16314 | -0.848 | -0.1926 | No | ||
130 | PANK1 | 670091 6220605 | 16416 | -0.906 | -0.1905 | No | ||
131 | CREM | 840156 6380438 6660041 6660168 | 16542 | -0.993 | -0.1889 | No | ||
132 | CEPT1 | 1940047 | 16558 | -0.998 | -0.1813 | No | ||
133 | TACSTD2 | 6660341 | 16702 | -1.089 | -0.1799 | No | ||
134 | SIPA1 | 5220687 | 16714 | -1.098 | -0.1712 | No | ||
135 | ADD3 | 4150739 5390600 | 16818 | -1.184 | -0.1668 | No | ||
136 | ADRBK1 | 1340333 | 17027 | -1.377 | -0.1665 | No | ||
137 | ARL3 | 5690725 | 17204 | -1.603 | -0.1625 | No | ||
138 | TSG101 | 770148 | 17360 | -1.802 | -0.1557 | No | ||
139 | PRDM2 | 780278 1940692 | 17534 | -2.092 | -0.1475 | No | ||
140 | PTPN7 | 3450110 | 17624 | -2.268 | -0.1332 | No | ||
141 | SCAMP3 | 2360707 | 18015 | -3.112 | -0.1281 | No | ||
142 | EIF4EBP2 | 5670279 | 18073 | -3.341 | -0.1030 | No | ||
143 | GADD45A | 2900717 | 18319 | -4.477 | -0.0786 | No | ||
144 | HSD11B1 | 450066 5550408 | 18421 | -5.285 | -0.0395 | No | ||
145 | CAP1 | 2650278 | 18491 | -5.943 | 0.0068 | No |