Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | wtNotch |
GeneSet | V$ER_Q6_01 |
Enrichment Score (ES) | 0.40756074 |
Normalized Enrichment Score (NES) | 1.1525569 |
Nominal p-value | 0.09703504 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | ALDOA | 6290672 | 47 | 5.798 | 0.0346 | Yes | ||
2 | EIF2B3 | 3290463 | 53 | 5.612 | 0.0703 | Yes | ||
3 | PCBP4 | 6350722 | 140 | 4.445 | 0.0942 | Yes | ||
4 | ATP5G1 | 5290019 | 245 | 3.817 | 0.1130 | Yes | ||
5 | ZFPM1 | 6760093 | 252 | 3.798 | 0.1371 | Yes | ||
6 | GNB1L | 3840368 5270215 | 382 | 3.302 | 0.1512 | Yes | ||
7 | SLC6A9 | 2470520 | 426 | 3.130 | 0.1690 | Yes | ||
8 | PHF5A | 2690519 | 451 | 3.056 | 0.1873 | Yes | ||
9 | SDC1 | 3440471 6350408 | 522 | 2.876 | 0.2019 | Yes | ||
10 | NFIL3 | 4070377 | 569 | 2.751 | 0.2171 | Yes | ||
11 | SLC25A1 | 4050402 | 574 | 2.736 | 0.2344 | Yes | ||
12 | B3GNT6 | 1340736 | 595 | 2.701 | 0.2506 | Yes | ||
13 | PPP1R16A | 5080239 | 680 | 2.567 | 0.2625 | Yes | ||
14 | PSMF1 | 5340056 | 830 | 2.303 | 0.2692 | Yes | ||
15 | TOMM40 | 6110017 | 939 | 2.111 | 0.2769 | Yes | ||
16 | AAMP | 2640059 | 964 | 2.081 | 0.2889 | Yes | ||
17 | POLE3 | 5270019 | 965 | 2.081 | 0.3023 | Yes | ||
18 | RTN4 | 50725 630647 870097 870184 | 1318 | 1.704 | 0.2941 | Yes | ||
19 | RHOB | 1500309 | 1412 | 1.615 | 0.2994 | Yes | ||
20 | LCP1 | 4280397 | 1419 | 1.608 | 0.3094 | Yes | ||
21 | RNMT | 1770500 | 1474 | 1.557 | 0.3165 | Yes | ||
22 | PDE6D | 3130537 3390014 | 1499 | 1.532 | 0.3250 | Yes | ||
23 | ACO2 | 4230600 | 1526 | 1.509 | 0.3333 | Yes | ||
24 | MT2A | 6860286 | 1566 | 1.469 | 0.3406 | Yes | ||
25 | NDRG2 | 450403 | 1637 | 1.406 | 0.3458 | Yes | ||
26 | GTPBP1 | 2230541 4560528 | 1661 | 1.384 | 0.3534 | Yes | ||
27 | PDZK1 | 2320128 | 1748 | 1.306 | 0.3571 | Yes | ||
28 | ATP5A1 | 1990722 | 1796 | 1.273 | 0.3627 | Yes | ||
29 | HSPG2 | 2510687 6220750 | 1893 | 1.192 | 0.3652 | Yes | ||
30 | FKBP4 | 870035 | 1910 | 1.178 | 0.3719 | Yes | ||
31 | TBX6 | 4730139 6840647 | 1939 | 1.156 | 0.3778 | Yes | ||
32 | CDKN2C | 5050750 5130148 | 2033 | 1.076 | 0.3796 | Yes | ||
33 | GREB1 | 1230707 4560056 | 2135 | 1.015 | 0.3806 | Yes | ||
34 | TPM3 | 670600 3170296 5670167 6650471 | 2176 | 1.000 | 0.3849 | Yes | ||
35 | PDHA1 | 5550397 | 2210 | 0.991 | 0.3894 | Yes | ||
36 | OTX2 | 1190471 | 2239 | 0.983 | 0.3942 | Yes | ||
37 | PKP4 | 3710400 5890097 | 2240 | 0.982 | 0.4005 | Yes | ||
38 | HIP2 | 2810095 3990369 4120301 | 2260 | 0.974 | 0.4057 | Yes | ||
39 | BRMS1 | 6860280 | 2378 | 0.896 | 0.4051 | Yes | ||
40 | DGCR8 | 3450632 | 2436 | 0.859 | 0.4076 | Yes | ||
41 | STMN1 | 1990717 | 2698 | 0.711 | 0.3980 | No | ||
42 | CDC14A | 4050132 | 2817 | 0.652 | 0.3957 | No | ||
43 | TRPS1 | 870100 | 2983 | 0.579 | 0.3905 | No | ||
44 | TSGA14 | 6660465 | 3037 | 0.559 | 0.3912 | No | ||
45 | SLC16A6 | 1690156 | 3045 | 0.555 | 0.3944 | No | ||
46 | PXN | 3290048 6400132 | 3080 | 0.546 | 0.3961 | No | ||
47 | BNIP3L | 1940347 | 3141 | 0.521 | 0.3961 | No | ||
48 | GAS7 | 2120358 6450494 | 3203 | 0.498 | 0.3960 | No | ||
49 | SLC25A5 | 1980672 | 3209 | 0.496 | 0.3989 | No | ||
50 | SRP68 | 4480731 | 3222 | 0.492 | 0.4014 | No | ||
51 | LRFN4 | 5670368 | 3505 | 0.392 | 0.3887 | No | ||
52 | RRBP1 | 2260477 5050440 | 3676 | 0.330 | 0.3815 | No | ||
53 | ERG | 50154 1770739 | 3890 | 0.277 | 0.3718 | No | ||
54 | APBA2BP | 5700341 | 3990 | 0.254 | 0.3680 | No | ||
55 | ZFP36L2 | 510180 | 3995 | 0.253 | 0.3694 | No | ||
56 | TINAG | 1570609 6510215 | 4031 | 0.247 | 0.3691 | No | ||
57 | AOC2 | 520348 3120008 | 4183 | 0.221 | 0.3624 | No | ||
58 | TLX2 | 1090128 2900451 | 4317 | 0.202 | 0.3564 | No | ||
59 | MID1 | 4070114 4760458 | 4475 | 0.182 | 0.3491 | No | ||
60 | ERN1 | 2360403 | 4649 | 0.163 | 0.3407 | No | ||
61 | RBBP9 | 2480139 | 4889 | 0.141 | 0.3287 | No | ||
62 | OTP | 2630070 | 5120 | 0.124 | 0.3170 | No | ||
63 | NR1D1 | 2360471 770746 6590204 | 5147 | 0.122 | 0.3164 | No | ||
64 | UBE2R2 | 1230504 | 5187 | 0.119 | 0.3150 | No | ||
65 | KIRREL3 | 2630195 | 5298 | 0.113 | 0.3098 | No | ||
66 | RAP2C | 1690132 | 5324 | 0.111 | 0.3091 | No | ||
67 | GLRA2 | 7000019 | 5345 | 0.111 | 0.3088 | No | ||
68 | CNTN4 | 1780300 5570577 6370019 | 5359 | 0.110 | 0.3088 | No | ||
69 | HOXA3 | 3610632 6020358 | 5397 | 0.107 | 0.3074 | No | ||
70 | HOXB3 | 520292 | 5445 | 0.105 | 0.3056 | No | ||
71 | COVA1 | 5340504 5360594 | 5507 | 0.101 | 0.3029 | No | ||
72 | ZIC1 | 670113 | 5512 | 0.101 | 0.3033 | No | ||
73 | STARD6 | 6940541 | 5552 | 0.099 | 0.3019 | No | ||
74 | WNT11 | 1230278 | 5632 | 0.095 | 0.2982 | No | ||
75 | GCM1 | 6510687 | 5682 | 0.093 | 0.2961 | No | ||
76 | GFAP | 2060092 | 5696 | 0.092 | 0.2960 | No | ||
77 | MAP2K7 | 2260086 | 5781 | 0.087 | 0.2920 | No | ||
78 | FBXL14 | 4670315 | 6099 | 0.075 | 0.2753 | No | ||
79 | MCC | 620750 | 6173 | 0.072 | 0.2718 | No | ||
80 | FGF9 | 1050195 | 6299 | 0.068 | 0.2655 | No | ||
81 | MRVI1 | 4810338 4850601 5900441 | 6342 | 0.066 | 0.2636 | No | ||
82 | LIFR | 3360068 3830102 | 6389 | 0.064 | 0.2615 | No | ||
83 | JARID2 | 6290538 | 6407 | 0.064 | 0.2610 | No | ||
84 | HOXA10 | 6110397 7100458 | 6421 | 0.063 | 0.2607 | No | ||
85 | MAGED1 | 6650332 | 6591 | 0.058 | 0.2519 | No | ||
86 | NOG | 2320609 | 6622 | 0.057 | 0.2507 | No | ||
87 | PTHR1 | 2640711 3360647 | 6774 | 0.053 | 0.2428 | No | ||
88 | GRID2 | 2680242 | 6824 | 0.051 | 0.2405 | No | ||
89 | CHRDL1 | 1580037 6380204 | 6954 | 0.049 | 0.2338 | No | ||
90 | PURA | 3870156 | 7018 | 0.047 | 0.2307 | No | ||
91 | SLC10A2 | 110537 | 7158 | 0.044 | 0.2234 | No | ||
92 | SYNJ2BP | 4150672 6770706 | 7207 | 0.043 | 0.2211 | No | ||
93 | FBXW7 | 4210338 7050280 | 7438 | 0.038 | 0.2089 | No | ||
94 | ESRRB | 3870082 | 7466 | 0.037 | 0.2076 | No | ||
95 | DNMT3A | 4050068 4810717 | 7769 | 0.032 | 0.1915 | No | ||
96 | RIMS4 | 6110500 | 7771 | 0.032 | 0.1916 | No | ||
97 | WNT3 | 2360685 | 7832 | 0.031 | 0.1885 | No | ||
98 | BHLHB5 | 6510520 | 7933 | 0.029 | 0.1833 | No | ||
99 | PFTK1 | 1780181 | 8011 | 0.027 | 0.1793 | No | ||
100 | PCDH8 | 2360047 4200452 | 8530 | 0.018 | 0.1513 | No | ||
101 | CALD1 | 1770129 1940397 | 8546 | 0.018 | 0.1506 | No | ||
102 | CLDN12 | 6350341 | 8694 | 0.015 | 0.1427 | No | ||
103 | NKX2-2 | 4150731 | 8814 | 0.013 | 0.1364 | No | ||
104 | GPR3 | 2970452 | 8962 | 0.011 | 0.1285 | No | ||
105 | B3GALT2 | 430136 | 9017 | 0.010 | 0.1256 | No | ||
106 | LRRN1 | 3290154 | 9225 | 0.007 | 0.1144 | No | ||
107 | GNAI1 | 4560390 | 9271 | 0.006 | 0.1120 | No | ||
108 | DCX | 130075 5360025 7050673 | 9304 | 0.006 | 0.1103 | No | ||
109 | TREX2 | 4920707 | 9473 | 0.003 | 0.1012 | No | ||
110 | SPOCK2 | 6650369 | 9521 | 0.003 | 0.0987 | No | ||
111 | BTBD3 | 1980041 2510577 3190053 4200746 | 9535 | 0.002 | 0.0980 | No | ||
112 | S100A5 | 4120592 | 9916 | -0.003 | 0.0774 | No | ||
113 | CDKL5 | 2450070 | 10141 | -0.006 | 0.0653 | No | ||
114 | PDE1A | 1050458 2570563 | 10405 | -0.010 | 0.0511 | No | ||
115 | TBC1D15 | 870673 | 10596 | -0.013 | 0.0409 | No | ||
116 | PAK1IP1 | 2230438 | 10706 | -0.015 | 0.0351 | No | ||
117 | PGF | 4810593 | 10789 | -0.016 | 0.0307 | No | ||
118 | GRM8 | 4780082 | 10889 | -0.018 | 0.0255 | No | ||
119 | FIGN | 7000601 | 11187 | -0.023 | 0.0095 | No | ||
120 | MITF | 380056 | 11505 | -0.028 | -0.0075 | No | ||
121 | POU3F3 | 6400047 | 11514 | -0.029 | -0.0077 | No | ||
122 | PAM | 5290528 | 11515 | -0.029 | -0.0076 | No | ||
123 | PPARA | 2060026 | 11623 | -0.031 | -0.0132 | No | ||
124 | TLX3 | 510619 | 11630 | -0.031 | -0.0133 | No | ||
125 | EGFL9 | 1410091 | 11663 | -0.031 | -0.0148 | No | ||
126 | CREB5 | 2320368 | 11678 | -0.032 | -0.0154 | No | ||
127 | APEX2 | 3780044 | 12106 | -0.041 | -0.0383 | No | ||
128 | GNRHR | 130438 | 12150 | -0.042 | -0.0404 | No | ||
129 | PRDM1 | 3170347 3520301 | 12786 | -0.059 | -0.0744 | No | ||
130 | SRPK2 | 6380341 | 12963 | -0.065 | -0.0835 | No | ||
131 | HIPK2 | 6350647 | 12971 | -0.065 | -0.0835 | No | ||
132 | ONECUT2 | 1340008 | 12979 | -0.065 | -0.0835 | No | ||
133 | ATP6V0A4 | 360100 | 13193 | -0.074 | -0.0945 | No | ||
134 | FSHB | 7100592 | 13233 | -0.075 | -0.0962 | No | ||
135 | IL23R | 3990014 | 13235 | -0.075 | -0.0957 | No | ||
136 | DDR1 | 2060044 5220180 | 13248 | -0.076 | -0.0959 | No | ||
137 | ISL1 | 4810239 | 13435 | -0.085 | -0.1055 | No | ||
138 | ERBB4 | 4610400 4810017 | 13448 | -0.085 | -0.1056 | No | ||
139 | SHH | 5570400 | 13460 | -0.086 | -0.1056 | No | ||
140 | HOXB9 | 2640687 | 13581 | -0.091 | -0.1115 | No | ||
141 | LRRN3 | 1450133 | 13707 | -0.100 | -0.1177 | No | ||
142 | LRP5 | 2100397 3170484 | 13728 | -0.101 | -0.1181 | No | ||
143 | RAB11FIP1 | 2470333 | 13876 | -0.112 | -0.1254 | No | ||
144 | GABARAPL2 | 610204 3360047 | 14008 | -0.121 | -0.1317 | No | ||
145 | SCNN1A | 4730019 | 14100 | -0.128 | -0.1358 | No | ||
146 | TBR1 | 5130053 | 14237 | -0.142 | -0.1423 | No | ||
147 | HOXB7 | 4540706 4610358 | 14615 | -0.184 | -0.1615 | No | ||
148 | SPRED1 | 6940706 | 14911 | -0.237 | -0.1760 | No | ||
149 | NR4A2 | 60273 | 14939 | -0.245 | -0.1759 | No | ||
150 | NNT | 540253 1170471 5550092 6760397 | 15402 | -0.369 | -0.1986 | No | ||
151 | TCF7 | 3800736 5390181 | 15547 | -0.431 | -0.2037 | No | ||
152 | SP6 | 60484 510452 2690333 | 15576 | -0.441 | -0.2023 | No | ||
153 | COPZ2 | 1780010 2360020 4070373 | 15688 | -0.492 | -0.2052 | No | ||
154 | ZIC4 | 1500082 | 15724 | -0.510 | -0.2038 | No | ||
155 | CKB | 4560632 | 15756 | -0.524 | -0.2022 | No | ||
156 | RBMS1 | 6400014 | 15793 | -0.538 | -0.2007 | No | ||
157 | SLC4A7 | 2370056 | 15867 | -0.579 | -0.2009 | No | ||
158 | MNT | 4920575 | 16146 | -0.736 | -0.2113 | No | ||
159 | DNAJA2 | 2630253 6860358 | 16235 | -0.794 | -0.2110 | No | ||
160 | EIF4E | 1580403 70133 6380215 | 16348 | -0.866 | -0.2115 | No | ||
161 | NDUFB3 | 4610687 | 16540 | -0.993 | -0.2155 | No | ||
162 | GNA13 | 4590102 | 16772 | -1.147 | -0.2206 | No | ||
163 | CAMKK2 | 5270047 | 16998 | -1.342 | -0.2242 | No | ||
164 | KCNN3 | 6520600 6420138 | 17130 | -1.518 | -0.2216 | No | ||
165 | FCHSD2 | 5720092 | 17198 | -1.593 | -0.2150 | No | ||
166 | CHD2 | 4070039 | 17205 | -1.609 | -0.2050 | No | ||
167 | SLC9A1 | 2650093 | 17245 | -1.656 | -0.1965 | No | ||
168 | FGF13 | 630575 1570440 5360121 | 17286 | -1.707 | -0.1877 | No | ||
169 | IMMT | 870450 4280438 | 17315 | -1.731 | -0.1782 | No | ||
170 | EIF2AK3 | 4280161 | 17796 | -2.616 | -0.1874 | No | ||
171 | UHRF2 | 60050 840280 1340746 5080091 | 17842 | -2.723 | -0.1724 | No | ||
172 | MAP2K6 | 1230056 2940204 | 17854 | -2.745 | -0.1554 | No | ||
173 | DTNB | 2850100 | 17862 | -2.756 | -0.1381 | No | ||
174 | COX7A2L | 1500142 | 18019 | -3.119 | -0.1266 | No | ||
175 | PHF12 | 870400 3130687 | 18023 | -3.139 | -0.1066 | No | ||
176 | CD37 | 770273 | 18140 | -3.607 | -0.0897 | No | ||
177 | MAP1LC3A | 840519 5570605 | 18161 | -3.680 | -0.0672 | No | ||
178 | CIC | 6370161 | 18256 | -4.145 | -0.0458 | No | ||
179 | BCL6 | 940100 | 18397 | -5.006 | -0.0212 | No | ||
180 | SATB1 | 5670154 | 18410 | -5.157 | 0.0112 | No |