Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | wtNotch |
GeneSet | V$E2F_Q3 |
Enrichment Score (ES) | 0.44010663 |
Normalized Enrichment Score (NES) | 1.2317401 |
Nominal p-value | 0.061068702 |
FDR q-value | 1.0 |
FWER p-Value | 1.0 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | TCP1 | 2450100 5130524 | 76 | 5.073 | 0.0356 | Yes | ||
2 | RBBP7 | 430113 450450 2370309 | 218 | 3.950 | 0.0589 | Yes | ||
3 | SLC25A3 | 670112 | 262 | 3.748 | 0.0859 | Yes | ||
4 | IMPDH2 | 5220138 | 284 | 3.680 | 0.1136 | Yes | ||
5 | UNG | 3130110 6100364 | 463 | 3.028 | 0.1277 | Yes | ||
6 | HNRPA1 | 4670398 5050687 | 481 | 2.980 | 0.1501 | Yes | ||
7 | NCL | 2360463 4540279 | 534 | 2.844 | 0.1695 | Yes | ||
8 | GCH1 | 670364 6550358 | 591 | 2.707 | 0.1877 | Yes | ||
9 | SHMT1 | 5900132 | 692 | 2.540 | 0.2022 | Yes | ||
10 | APRIN | 2810050 | 717 | 2.508 | 0.2205 | Yes | ||
11 | HMGN2 | 3140091 | 779 | 2.385 | 0.2359 | Yes | ||
12 | RFC1 | 1190673 | 840 | 2.283 | 0.2505 | Yes | ||
13 | OLFML3 | 7100463 | 1086 | 1.930 | 0.2524 | Yes | ||
14 | LIG1 | 1980438 4540112 5570609 | 1120 | 1.886 | 0.2654 | Yes | ||
15 | ABCF2 | 630040 3140035 6450601 | 1207 | 1.804 | 0.2748 | Yes | ||
16 | DNAJC11 | 360465 3390215 | 1356 | 1.667 | 0.2799 | Yes | ||
17 | BAT3 | 1990594 | 1418 | 1.608 | 0.2892 | Yes | ||
18 | HIST1H2BK | 6130433 | 1481 | 1.551 | 0.2980 | Yes | ||
19 | PPP1R8 | 6290292 | 1489 | 1.542 | 0.3097 | Yes | ||
20 | TFRC | 4050551 | 1557 | 1.475 | 0.3176 | Yes | ||
21 | E2F1 | 5360093 | 1632 | 1.410 | 0.3246 | Yes | ||
22 | MCM6 | 60092 540181 6510110 | 1636 | 1.407 | 0.3355 | Yes | ||
23 | SLC38A1 | 520465 | 1683 | 1.365 | 0.3437 | Yes | ||
24 | SFRS2 | 50707 380593 | 1695 | 1.356 | 0.3537 | Yes | ||
25 | PRPS1 | 6350129 | 1706 | 1.347 | 0.3637 | Yes | ||
26 | MCM3 | 5570068 | 1745 | 1.310 | 0.3719 | Yes | ||
27 | NASP | 2260139 2940369 5130707 | 1798 | 1.270 | 0.3790 | Yes | ||
28 | MCM4 | 2760673 5420711 | 1842 | 1.237 | 0.3864 | Yes | ||
29 | TBX6 | 4730139 6840647 | 1939 | 1.156 | 0.3902 | Yes | ||
30 | POLA2 | 940519 | 2009 | 1.100 | 0.3951 | Yes | ||
31 | PIAS1 | 5340301 | 2027 | 1.084 | 0.4027 | Yes | ||
32 | CDC6 | 4570296 5360600 | 2164 | 1.001 | 0.4032 | Yes | ||
33 | DPYSL2 | 2100427 3130112 5700324 | 2183 | 0.999 | 0.4100 | Yes | ||
34 | DLST | 2320722 | 2365 | 0.903 | 0.4073 | Yes | ||
35 | RBBP4 | 6650528 | 2385 | 0.891 | 0.4132 | Yes | ||
36 | MCM7 | 3290292 5220056 | 2495 | 0.823 | 0.4138 | Yes | ||
37 | GMNN | 2630148 | 2566 | 0.779 | 0.4161 | Yes | ||
38 | EPHB2 | 1090288 1410377 2100541 | 2583 | 0.768 | 0.4212 | Yes | ||
39 | ZCCHC8 | 2260332 2350487 | 2697 | 0.712 | 0.4207 | Yes | ||
40 | STMN1 | 1990717 | 2698 | 0.711 | 0.4263 | Yes | ||
41 | CLTA | 450010 | 2763 | 0.673 | 0.4281 | Yes | ||
42 | KCNA1 | 2030594 | 2804 | 0.658 | 0.4311 | Yes | ||
43 | PHF15 | 6550066 6860673 | 2816 | 0.652 | 0.4356 | Yes | ||
44 | CPNE5 | 6380673 | 2827 | 0.648 | 0.4401 | Yes | ||
45 | MCM2 | 5050139 | 3072 | 0.548 | 0.4312 | No | ||
46 | KPNB1 | 1690138 | 3306 | 0.455 | 0.4221 | No | ||
47 | DNMT1 | 2260097 | 3343 | 0.447 | 0.4237 | No | ||
48 | SNPH | 2680484 | 3408 | 0.426 | 0.4236 | No | ||
49 | ERBB2IP | 580253 1090672 | 3449 | 0.410 | 0.4246 | No | ||
50 | PAPOLG | 2470400 | 3474 | 0.402 | 0.4265 | No | ||
51 | STAG2 | 4540132 | 3490 | 0.397 | 0.4288 | No | ||
52 | CDC25A | 3800184 | 3565 | 0.371 | 0.4277 | No | ||
53 | ADAMTS2 | 2650025 6370133 6840670 | 3686 | 0.328 | 0.4237 | No | ||
54 | SSBP3 | 870717 1050377 7040551 | 3805 | 0.298 | 0.4197 | No | ||
55 | NDUFA11 | 3780333 | 3821 | 0.293 | 0.4212 | No | ||
56 | CNOT3 | 130519 4480292 1990609 | 3924 | 0.271 | 0.4178 | No | ||
57 | CDCA7 | 3060097 | 4118 | 0.232 | 0.4091 | No | ||
58 | RAD51 | 6110450 6980280 | 4124 | 0.231 | 0.4107 | No | ||
59 | KCND2 | 1170128 2100112 | 4236 | 0.212 | 0.4063 | No | ||
60 | KLF4 | 1850022 3830239 5570750 | 4329 | 0.202 | 0.4029 | No | ||
61 | LASP1 | 1690528 2190341 6420341 | 4333 | 0.201 | 0.4043 | No | ||
62 | AP4M1 | 70609 3440128 | 4448 | 0.185 | 0.3996 | No | ||
63 | RHD | 4050168 | 4603 | 0.168 | 0.3926 | No | ||
64 | PRKDC | 1400072 4230541 | 4798 | 0.149 | 0.3832 | No | ||
65 | HS6ST3 | 5910138 | 4815 | 0.148 | 0.3835 | No | ||
66 | ATRX | 2340039 3610132 4210373 | 4830 | 0.146 | 0.3839 | No | ||
67 | PAQR4 | 730736 | 4879 | 0.142 | 0.3824 | No | ||
68 | SEMA5A | 6200110 6520435 | 4931 | 0.138 | 0.3807 | No | ||
69 | E2F3 | 50162 460180 | 5063 | 0.127 | 0.3746 | No | ||
70 | ARID4A | 520156 1050707 | 5087 | 0.126 | 0.3744 | No | ||
71 | RANBP1 | 430215 1090180 | 5116 | 0.124 | 0.3738 | No | ||
72 | GRIK2 | 4610164 | 5316 | 0.112 | 0.3639 | No | ||
73 | SALL1 | 5420020 7050195 | 5616 | 0.096 | 0.3485 | No | ||
74 | NRP2 | 4070400 5860041 6650446 | 5980 | 0.079 | 0.3295 | No | ||
75 | FBXO5 | 2630551 | 6573 | 0.059 | 0.2979 | No | ||
76 | STK35 | 2360121 | 6675 | 0.056 | 0.2929 | No | ||
77 | MRPL18 | 6560341 | 6894 | 0.050 | 0.2814 | No | ||
78 | CTDSP1 | 6650215 6940731 | 6971 | 0.048 | 0.2777 | No | ||
79 | HNRPD | 4120021 | 7148 | 0.044 | 0.2685 | No | ||
80 | ARHGAP6 | 2060121 | 7444 | 0.038 | 0.2528 | No | ||
81 | TOPBP1 | 6020333 | 7505 | 0.037 | 0.2499 | No | ||
82 | UFD1L | 870020 | 7530 | 0.036 | 0.2489 | No | ||
83 | CDC45L | 70537 3130114 | 7624 | 0.034 | 0.2441 | No | ||
84 | HIST1H1D | 3440446 | 7964 | 0.028 | 0.2260 | No | ||
85 | POLE2 | 6110041 | 8208 | 0.023 | 0.2130 | No | ||
86 | NPR3 | 1580239 | 8413 | 0.020 | 0.2021 | No | ||
87 | PODN | 3710068 | 8504 | 0.018 | 0.1974 | No | ||
88 | NUP153 | 7000452 | 9033 | 0.010 | 0.1689 | No | ||
89 | ONECUT1 | 6450136 | 9339 | 0.005 | 0.1524 | No | ||
90 | AP1S2 | 780279 4280707 | 9353 | 0.005 | 0.1517 | No | ||
91 | TREX2 | 4920707 | 9473 | 0.003 | 0.1453 | No | ||
92 | TBX3 | 2570672 | 10330 | -0.009 | 0.0990 | No | ||
93 | SEZ6 | 3450722 | 10347 | -0.009 | 0.0983 | No | ||
94 | PCSK1 | 2350148 | 10605 | -0.013 | 0.0844 | No | ||
95 | IPO7 | 2190746 | 10682 | -0.015 | 0.0804 | No | ||
96 | CACNA1G | 3060161 4810706 5550722 | 10723 | -0.015 | 0.0784 | No | ||
97 | EPHB1 | 4610056 | 10903 | -0.018 | 0.0688 | No | ||
98 | BARHL1 | 4210113 | 11111 | -0.022 | 0.0578 | No | ||
99 | ORC1L | 2370328 6110390 | 11192 | -0.023 | 0.0537 | No | ||
100 | FMO4 | 360735 | 11253 | -0.024 | 0.0506 | No | ||
101 | ASCL1 | 6650100 | 11383 | -0.026 | 0.0438 | No | ||
102 | PEG3 | 3710020 | 11492 | -0.028 | 0.0382 | No | ||
103 | SMAD6 | 870504 | 12022 | -0.039 | 0.0099 | No | ||
104 | CASP8AP2 | 5910593 | 12236 | -0.044 | -0.0013 | No | ||
105 | WEE1 | 3390070 | 13037 | -0.067 | -0.0441 | No | ||
106 | LHX5 | 2350097 | 13205 | -0.074 | -0.0526 | No | ||
107 | ADCY8 | 6760519 | 13229 | -0.075 | -0.0532 | No | ||
108 | DMD | 1740041 3990332 | 13292 | -0.078 | -0.0560 | No | ||
109 | CBX5 | 3830072 6290167 | 13506 | -0.088 | -0.0668 | No | ||
110 | MEIS1 | 1400575 | 13618 | -0.094 | -0.0721 | No | ||
111 | SLC6A4 | 2230372 | 13678 | -0.098 | -0.0745 | No | ||
112 | DDB2 | 3520341 4610168 4850184 4920717 | 13864 | -0.111 | -0.0837 | No | ||
113 | NOL4 | 5050446 5360519 | 13870 | -0.111 | -0.0831 | No | ||
114 | EZH2 | 6130605 6380524 | 14010 | -0.121 | -0.0897 | No | ||
115 | TRIM47 | 5080717 | 14142 | -0.133 | -0.0957 | No | ||
116 | UXT | 110019 5080066 | 14307 | -0.149 | -0.1034 | No | ||
117 | JPH1 | 610739 | 14363 | -0.155 | -0.1052 | No | ||
118 | MCM8 | 6130743 | 14383 | -0.157 | -0.1050 | No | ||
119 | INSM1 | 3450671 | 14998 | -0.258 | -0.1362 | No | ||
120 | MDGA1 | 1170139 | 15106 | -0.280 | -0.1398 | No | ||
121 | ATAD2 | 870242 2260687 | 15260 | -0.328 | -0.1455 | No | ||
122 | PVRL1 | 2570167 5220519 5890500 3190309 | 15385 | -0.364 | -0.1494 | No | ||
123 | H2AFZ | 1470168 | 15403 | -0.369 | -0.1474 | No | ||
124 | HIST1H2AH | 3710333 | 15806 | -0.544 | -0.1649 | No | ||
125 | E2F7 | 4200056 | 15843 | -0.563 | -0.1625 | No | ||
126 | SFRS1 | 2360440 | 15931 | -0.616 | -0.1623 | No | ||
127 | ATE1 | 290491 6940722 | 15949 | -0.628 | -0.1584 | No | ||
128 | CTCF | 5340017 | 15969 | -0.635 | -0.1544 | No | ||
129 | ING3 | 110438 2060390 | 16095 | -0.708 | -0.1556 | No | ||
130 | KLF5 | 3840348 | 16139 | -0.734 | -0.1522 | No | ||
131 | PLK4 | 430162 5720110 | 16214 | -0.777 | -0.1501 | No | ||
132 | MAT2A | 4070026 4730079 6020280 | 16267 | -0.813 | -0.1466 | No | ||
133 | PCSK4 | 130687 670711 3170075 6400411 | 16535 | -0.989 | -0.1533 | No | ||
134 | FLI1 | 3990142 | 16561 | -0.999 | -0.1468 | No | ||
135 | USP1 | 2760541 5690438 6220673 | 16595 | -1.011 | -0.1407 | No | ||
136 | MAZ | 3360121 6940750 | 16660 | -1.052 | -0.1359 | No | ||
137 | HTF9C | 3190048 4120132 | 16779 | -1.153 | -0.1333 | No | ||
138 | PCNA | 940754 | 17042 | -1.404 | -0.1365 | No | ||
139 | PPP1CC | 6380300 2510647 | 17432 | -1.914 | -0.1425 | No | ||
140 | SLC25A14 | 4760180 | 17541 | -2.107 | -0.1319 | No | ||
141 | PHF13 | 450435 | 17574 | -2.159 | -0.1167 | No | ||
142 | PIM1 | 630047 | 17788 | -2.608 | -0.1078 | No | ||
143 | MXD3 | 6220014 | 17810 | -2.641 | -0.0883 | No | ||
144 | PHF12 | 870400 3130687 | 18023 | -3.139 | -0.0752 | No | ||
145 | RAB11B | 3990609 | 18149 | -3.633 | -0.0535 | No | ||
146 | SYT11 | 630433 | 18333 | -4.582 | -0.0275 | No | ||
147 | DCK | 6900411 | 18439 | -5.467 | 0.0096 | No |