Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | V$CP2_02 |
Enrichment Score (ES) | -0.59234405 |
Normalized Enrichment Score (NES) | -1.5909057 |
Nominal p-value | 0.0 |
FDR q-value | 0.077170365 |
FWER p-Value | 0.382 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | DDIT4 | 2570408 | 238 | 3.847 | 0.0140 | No | ||
2 | KLHDC3 | 3830717 | 386 | 3.274 | 0.0289 | No | ||
3 | PHPT1 | 7050537 | 434 | 3.103 | 0.0480 | No | ||
4 | FKBP2 | 2320025 | 1097 | 1.915 | 0.0255 | No | ||
5 | GMPPB | 4610538 | 1684 | 1.365 | 0.0033 | No | ||
6 | TRAF4 | 3060041 4920528 6980286 | 1757 | 1.298 | 0.0084 | No | ||
7 | RYR1 | 2510114 3130408 3710086 | 1930 | 1.163 | 0.0072 | No | ||
8 | MRPL14 | 2370168 | 1989 | 1.114 | 0.0119 | No | ||
9 | TGFBR2 | 1780711 1980537 6550398 | 2076 | 1.050 | 0.0146 | No | ||
10 | CS | 5080600 | 2114 | 1.026 | 0.0197 | No | ||
11 | HTATIP | 5360739 | 2315 | 0.933 | 0.0154 | No | ||
12 | MORF4L2 | 6450133 | 2431 | 0.863 | 0.0152 | No | ||
13 | CAMK2G | 630097 | 2613 | 0.751 | 0.0106 | No | ||
14 | PRKACA | 2640731 4050048 | 2768 | 0.671 | 0.0070 | No | ||
15 | SLC2A9 | 3290301 | 2884 | 0.626 | 0.0051 | No | ||
16 | SHB | 4920494 | 2904 | 0.615 | 0.0084 | No | ||
17 | PRKAG1 | 6450091 | 2965 | 0.588 | 0.0092 | No | ||
18 | UBE1 | 4150139 7050463 | 3061 | 0.550 | 0.0079 | No | ||
19 | PPP1R16B | 3520300 | 3106 | 0.536 | 0.0093 | No | ||
20 | RASSF1 | 2760364 4850725 | 3223 | 0.491 | 0.0064 | No | ||
21 | RBBP6 | 2320129 | 3246 | 0.481 | 0.0086 | No | ||
22 | MMP11 | 1980619 | 3396 | 0.431 | 0.0036 | No | ||
23 | SLC25A28 | 6590600 | 3515 | 0.387 | -0.0001 | No | ||
24 | TRERF1 | 6370017 6940138 | 3557 | 0.373 | 0.0002 | No | ||
25 | SRMS | 5360402 | 3758 | 0.305 | -0.0085 | No | ||
26 | WNT10B | 510050 | 3781 | 0.301 | -0.0076 | No | ||
27 | PPP2R5C | 3310121 6650672 | 3893 | 0.277 | -0.0116 | No | ||
28 | NR2F1 | 4120528 360402 | 3939 | 0.267 | -0.0122 | No | ||
29 | LHX2 | 3610463 | 4002 | 0.252 | -0.0138 | No | ||
30 | NRIP2 | 5390288 | 4022 | 0.249 | -0.0131 | No | ||
31 | PAX2 | 6040270 7000133 | 4120 | 0.232 | -0.0167 | No | ||
32 | EPN3 | 2350592 | 4251 | 0.210 | -0.0223 | No | ||
33 | KCTD15 | 2810735 | 4285 | 0.207 | -0.0227 | No | ||
34 | CNTN6 | 2630711 | 4326 | 0.202 | -0.0234 | No | ||
35 | TNNC1 | 1990575 | 4374 | 0.195 | -0.0246 | No | ||
36 | FOXP2 | 3520561 4150372 4760524 | 4450 | 0.185 | -0.0274 | No | ||
37 | EFNA3 | 6370390 | 4477 | 0.182 | -0.0275 | No | ||
38 | FOXL2 | 5670537 | 4541 | 0.175 | -0.0297 | No | ||
39 | NISCH | 4850301 | 4550 | 0.174 | -0.0289 | No | ||
40 | ALDH3B1 | 4210010 6940403 | 4722 | 0.156 | -0.0371 | No | ||
41 | CHD4 | 5420059 6130338 6380717 | 5129 | 0.123 | -0.0582 | No | ||
42 | NR1D1 | 2360471 770746 6590204 | 5147 | 0.122 | -0.0583 | No | ||
43 | TBX2 | 1990563 | 5193 | 0.119 | -0.0599 | No | ||
44 | HOXB6 | 4210739 | 5417 | 0.106 | -0.0712 | No | ||
45 | DSCAM | 1780050 2450731 2810438 | 5471 | 0.103 | -0.0734 | No | ||
46 | GPRC5C | 1580372 | 5528 | 0.100 | -0.0757 | No | ||
47 | CREB1 | 1500717 2230358 3610600 6550601 | 5595 | 0.097 | -0.0786 | No | ||
48 | GPC3 | 6180735 | 5646 | 0.095 | -0.0807 | No | ||
49 | LYN | 6040600 | 5783 | 0.087 | -0.0874 | No | ||
50 | DHH | 2120433 | 5837 | 0.085 | -0.0897 | No | ||
51 | FEV | 840369 5860139 | 6084 | 0.075 | -0.1025 | No | ||
52 | YWHAG | 3780341 | 6223 | 0.070 | -0.1095 | No | ||
53 | FGF9 | 1050195 | 6299 | 0.068 | -0.1131 | No | ||
54 | RNF121 | 110079 1580279 | 6717 | 0.054 | -0.1353 | No | ||
55 | PAPPA | 4230463 | 6839 | 0.051 | -0.1415 | No | ||
56 | MAPRE3 | 7050504 | 7047 | 0.046 | -0.1524 | No | ||
57 | BMP4 | 380113 | 7134 | 0.044 | -0.1568 | No | ||
58 | RTN1 | 4150452 4850176 | 7324 | 0.040 | -0.1667 | No | ||
59 | ETV1 | 70735 2940603 5080463 | 7339 | 0.040 | -0.1672 | No | ||
60 | RPL41 | 6940112 | 7639 | 0.034 | -0.1832 | No | ||
61 | NNAT | 4920053 5130253 | 7885 | 0.030 | -0.1962 | No | ||
62 | BDNF | 2940128 3520368 | 7993 | 0.028 | -0.2018 | No | ||
63 | PFTK1 | 1780181 | 8011 | 0.027 | -0.2026 | No | ||
64 | UPK2 | 60176 | 8062 | 0.026 | -0.2051 | No | ||
65 | COX8C | 4670154 | 8107 | 0.025 | -0.2073 | No | ||
66 | STARD13 | 540722 | 8392 | 0.021 | -0.2225 | No | ||
67 | KIF1C | 2480484 | 8424 | 0.020 | -0.2241 | No | ||
68 | PODN | 3710068 | 8504 | 0.018 | -0.2282 | No | ||
69 | CALD1 | 1770129 1940397 | 8546 | 0.018 | -0.2303 | No | ||
70 | MID2 | 4120309 | 8622 | 0.017 | -0.2343 | No | ||
71 | GSH1 | 2760242 | 8956 | 0.011 | -0.2522 | No | ||
72 | PITX2 | 870537 2690139 | 8976 | 0.011 | -0.2532 | No | ||
73 | ODC1 | 5670168 | 9071 | 0.009 | -0.2582 | No | ||
74 | DCX | 130075 5360025 7050673 | 9304 | 0.006 | -0.2707 | No | ||
75 | HPCAL1 | 1980129 2350348 | 9370 | 0.005 | -0.2742 | No | ||
76 | GNB3 | 1230167 | 9401 | 0.004 | -0.2758 | No | ||
77 | PTHLH | 5290739 | 9842 | -0.002 | -0.2997 | No | ||
78 | BRUNOL6 | 6840373 | 10234 | -0.008 | -0.3208 | No | ||
79 | TBC1D5 | 5360619 6130603 | 10292 | -0.009 | -0.3238 | No | ||
80 | KCNE3 | 5550195 | 10444 | -0.011 | -0.3319 | No | ||
81 | HIF1A | 5670605 | 10446 | -0.011 | -0.3319 | No | ||
82 | P518 | 3610435 | 10467 | -0.011 | -0.3329 | No | ||
83 | ARX | 6900504 | 10560 | -0.013 | -0.3378 | No | ||
84 | PCDHB4 | 670184 | 10599 | -0.013 | -0.3398 | No | ||
85 | PLXNA3 | 7050164 | 10727 | -0.015 | -0.3465 | No | ||
86 | STAC2 | 7100022 | 10906 | -0.018 | -0.3561 | No | ||
87 | CITED1 | 2350670 | 10908 | -0.018 | -0.3560 | No | ||
88 | NRXN3 | 1400546 3360471 | 10916 | -0.018 | -0.3562 | No | ||
89 | FRMD3 | 3440731 | 10940 | -0.019 | -0.3573 | No | ||
90 | NTRK3 | 4050687 4070167 4610026 6100484 | 11202 | -0.023 | -0.3713 | No | ||
91 | PAK7 | 3830164 | 11352 | -0.026 | -0.3792 | No | ||
92 | XPNPEP1 | 2640750 3850315 6200242 | 11500 | -0.028 | -0.3870 | No | ||
93 | TLX3 | 510619 | 11630 | -0.031 | -0.3938 | No | ||
94 | NFATC4 | 2470735 | 11728 | -0.033 | -0.3988 | No | ||
95 | ARHGAP5 | 2510619 3360035 | 12137 | -0.042 | -0.4206 | No | ||
96 | DSC2 | 840484 | 12245 | -0.044 | -0.4261 | No | ||
97 | AQP6 | 510736 1570484 | 12261 | -0.045 | -0.4266 | No | ||
98 | TUFT1 | 540047 2370010 | 12424 | -0.048 | -0.4350 | No | ||
99 | CAPN6 | 1740168 | 12474 | -0.049 | -0.4373 | No | ||
100 | FOXA1 | 3710609 | 12503 | -0.050 | -0.4385 | No | ||
101 | C1QTNF5 | 1690402 | 12710 | -0.056 | -0.4493 | No | ||
102 | ADRA1A | 1230446 2260390 | 13031 | -0.067 | -0.4662 | No | ||
103 | DDR1 | 2060044 5220180 | 13248 | -0.076 | -0.4773 | No | ||
104 | TXNL5 | 1190609 1400164 | 13518 | -0.089 | -0.4913 | No | ||
105 | HSPA1L | 4010538 | 13553 | -0.090 | -0.4925 | No | ||
106 | MDK | 3840020 | 13588 | -0.092 | -0.4937 | No | ||
107 | MOGAT2 | 60139 | 13594 | -0.092 | -0.4933 | No | ||
108 | NOL4 | 5050446 5360519 | 13870 | -0.111 | -0.5074 | No | ||
109 | LTBP1 | 780035 2100746 2760402 3780551 6550184 6860193 | 13980 | -0.119 | -0.5125 | No | ||
110 | SLC26A9 | 3440722 5340088 7510093 | 14257 | -0.144 | -0.5265 | No | ||
111 | IRX3 | 4200112 | 14544 | -0.173 | -0.5408 | No | ||
112 | GNAQ | 430670 4210131 5900736 | 14693 | -0.195 | -0.5474 | No | ||
113 | KIF5A | 510435 | 15009 | -0.260 | -0.5627 | No | ||
114 | BTBD14B | 3520601 4280162 | 15051 | -0.267 | -0.5630 | No | ||
115 | LDB2 | 5670441 6110170 | 15269 | -0.330 | -0.5725 | No | ||
116 | RHBDF1 | 380538 | 15352 | -0.355 | -0.5744 | No | ||
117 | MAPK3 | 580161 4780035 | 15356 | -0.356 | -0.5721 | No | ||
118 | CPNE1 | 3440131 | 15395 | -0.367 | -0.5716 | No | ||
119 | ZNF385 | 450176 4810358 | 15598 | -0.448 | -0.5794 | No | ||
120 | SCAMP5 | 5550368 6290021 | 15814 | -0.547 | -0.5873 | No | ||
121 | DDAH2 | 4480551 | 15909 | -0.606 | -0.5881 | Yes | ||
122 | NEK8 | 5700180 | 15936 | -0.619 | -0.5852 | Yes | ||
123 | TLN1 | 6590411 | 16041 | -0.675 | -0.5861 | Yes | ||
124 | KIFAP3 | 3800524 4590082 6940075 | 16127 | -0.728 | -0.5856 | Yes | ||
125 | MNT | 4920575 | 16146 | -0.736 | -0.5815 | Yes | ||
126 | GRB7 | 2100471 | 16160 | -0.742 | -0.5770 | Yes | ||
127 | ATP10D | 4850139 | 16402 | -0.901 | -0.5838 | Yes | ||
128 | CRK | 1230162 4780128 | 16534 | -0.989 | -0.5840 | Yes | ||
129 | FLOT2 | 50358 4210068 5080397 | 16549 | -0.996 | -0.5778 | Yes | ||
130 | FLI1 | 3990142 | 16561 | -0.999 | -0.5714 | Yes | ||
131 | RAB10 | 2360008 5890020 | 16665 | -1.054 | -0.5696 | Yes | ||
132 | H3F3B | 1410300 | 16668 | -1.056 | -0.5623 | Yes | ||
133 | EPC1 | 1570050 5290095 6900193 | 16678 | -1.065 | -0.5554 | Yes | ||
134 | PRKCH | 5720079 | 16926 | -1.270 | -0.5599 | Yes | ||
135 | TRPV2 | 7100348 | 17011 | -1.355 | -0.5550 | Yes | ||
136 | RHBDL1 | 1500736 | 17135 | -1.523 | -0.5510 | Yes | ||
137 | SLC9A1 | 2650093 | 17245 | -1.656 | -0.5454 | Yes | ||
138 | BACH1 | 290195 | 17260 | -1.672 | -0.5344 | Yes | ||
139 | HCFC1 | 2260008 | 17439 | -1.921 | -0.5307 | Yes | ||
140 | SLC25A14 | 4760180 | 17541 | -2.107 | -0.5214 | Yes | ||
141 | GSK3B | 5360348 | 17703 | -2.429 | -0.5132 | Yes | ||
142 | LZTS2 | 2260440 | 17730 | -2.476 | -0.4973 | Yes | ||
143 | GLTP | 3440603 | 17752 | -2.527 | -0.4808 | Yes | ||
144 | TRIM8 | 6130441 | 17757 | -2.538 | -0.4633 | Yes | ||
145 | JUNB | 4230048 | 17886 | -2.809 | -0.4506 | Yes | ||
146 | DUSP6 | 5910286 7100070 | 18031 | -3.173 | -0.4362 | Yes | ||
147 | GABARAP | 1450286 | 18075 | -3.356 | -0.4151 | Yes | ||
148 | NGFRAP1 | 6770195 | 18076 | -3.356 | -0.3917 | Yes | ||
149 | FBS1 | 2570520 | 18135 | -3.567 | -0.3699 | Yes | ||
150 | NRF1 | 2650195 | 18139 | -3.600 | -0.3450 | Yes | ||
151 | MAST2 | 6200348 | 18154 | -3.654 | -0.3202 | Yes | ||
152 | PTCRA | 6940142 | 18239 | -4.054 | -0.2964 | Yes | ||
153 | PPP1R9B | 3130619 | 18306 | -4.410 | -0.2692 | Yes | ||
154 | BCL11B | 2680673 | 18360 | -4.729 | -0.2391 | Yes | ||
155 | DNAJB1 | 1090041 | 18371 | -4.807 | -0.2060 | Yes | ||
156 | DEF6 | 840593 | 18398 | -5.008 | -0.1725 | Yes | ||
157 | CDC42EP3 | 2480138 | 18436 | -5.438 | -0.1365 | Yes | ||
158 | CAP1 | 2650278 | 18491 | -5.943 | -0.0979 | Yes | ||
159 | KCNH2 | 1170451 | 18545 | -6.937 | -0.0524 | Yes | ||
160 | CLDN4 | 4920739 | 18581 | -8.039 | 0.0019 | Yes |