Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | TTGCCAA,MIR-182 |
Enrichment Score (ES) | -0.57259136 |
Normalized Enrichment Score (NES) | -1.5816512 |
Nominal p-value | 0.0 |
FDR q-value | 0.080095984 |
FWER p-Value | 0.431 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | PPIL1 | 6350435 | 219 | 3.947 | 0.0083 | No | ||
2 | NCALD | 730176 | 317 | 3.541 | 0.0212 | No | ||
3 | CFL1 | 2340735 | 498 | 2.954 | 0.0266 | No | ||
4 | ARHGEF3 | 3440156 | 707 | 2.525 | 0.0283 | No | ||
5 | DAZAP2 | 6200102 | 998 | 2.034 | 0.0229 | No | ||
6 | DENR | 4120176 | 1000 | 2.031 | 0.0333 | No | ||
7 | MBNL2 | 3450707 | 1087 | 1.929 | 0.0385 | No | ||
8 | AUP1 | 4150075 6980551 | 1088 | 1.929 | 0.0484 | No | ||
9 | PYGO2 | 360494 | 1230 | 1.784 | 0.0499 | No | ||
10 | CORO1C | 4570397 | 1309 | 1.709 | 0.0544 | No | ||
11 | RTN4 | 50725 630647 870097 870184 | 1318 | 1.704 | 0.0628 | No | ||
12 | TEX2 | 1740504 2480102 3060494 | 1448 | 1.587 | 0.0639 | No | ||
13 | ATP2A2 | 1090075 3990279 | 1522 | 1.512 | 0.0677 | No | ||
14 | MYOHD1 | 1410520 | 1832 | 1.246 | 0.0573 | No | ||
15 | EVI5 | 6380040 | 1999 | 1.104 | 0.0539 | No | ||
16 | SS18L1 | 4610180 6550068 | 2072 | 1.051 | 0.0554 | No | ||
17 | YAF2 | 940053 | 2140 | 1.013 | 0.0569 | No | ||
18 | PPP3R1 | 1190041 1570487 | 2170 | 1.000 | 0.0605 | No | ||
19 | DCUN1D1 | 2360332 | 2382 | 0.893 | 0.0536 | No | ||
20 | SNX4 | 1980358 | 2390 | 0.885 | 0.0578 | No | ||
21 | RALGDS | 430463 | 2606 | 0.758 | 0.0500 | No | ||
22 | TSNAX | 3450279 | 2720 | 0.700 | 0.0474 | No | ||
23 | VAMP3 | 7100050 | 2790 | 0.663 | 0.0471 | No | ||
24 | LIMK1 | 5080064 | 2894 | 0.620 | 0.0447 | No | ||
25 | P2RX4 | 2060497 6650162 | 2952 | 0.592 | 0.0446 | No | ||
26 | ADCY6 | 450364 6290670 6940286 | 3129 | 0.525 | 0.0377 | No | ||
27 | SNAP23 | 2480722 5390315 | 3262 | 0.475 | 0.0330 | No | ||
28 | KDELR1 | 6760504 | 3302 | 0.457 | 0.0332 | No | ||
29 | SMAD1 | 630537 1850333 | 3487 | 0.399 | 0.0253 | No | ||
30 | EGR3 | 6940128 | 3503 | 0.392 | 0.0265 | No | ||
31 | RAC1 | 4810687 | 3509 | 0.390 | 0.0282 | No | ||
32 | KPNA3 | 7040088 | 3572 | 0.369 | 0.0267 | No | ||
33 | SEPT9 | 1940040 | 3608 | 0.354 | 0.0266 | No | ||
34 | ATP1B3 | 6040128 | 3779 | 0.301 | 0.0189 | No | ||
35 | CDV3 | 1940577 | 4018 | 0.249 | 0.0073 | No | ||
36 | ARRDC3 | 4610390 | 4025 | 0.249 | 0.0082 | No | ||
37 | RHOBTB1 | 1410010 | 4108 | 0.234 | 0.0049 | No | ||
38 | UBXD3 | 5050193 | 4242 | 0.212 | -0.0012 | No | ||
39 | INSIG1 | 1500332 3450458 4540301 | 4361 | 0.197 | -0.0066 | No | ||
40 | NFASC | 1940619 2470156 4590168 6840524 | 4397 | 0.192 | -0.0075 | No | ||
41 | HOXA9 | 610494 4730040 5130601 | 4619 | 0.166 | -0.0187 | No | ||
42 | EIF2C1 | 6900551 | 4650 | 0.163 | -0.0195 | No | ||
43 | THBS2 | 2850136 | 4892 | 0.141 | -0.0319 | No | ||
44 | EDNRB | 4280717 6400435 | 4894 | 0.140 | -0.0312 | No | ||
45 | SEPT7 | 2760685 | 4906 | 0.140 | -0.0311 | No | ||
46 | QKI | 5220093 6130044 | 5026 | 0.130 | -0.0369 | No | ||
47 | CEBPA | 5690519 | 5156 | 0.122 | -0.0433 | No | ||
48 | UBE2R2 | 1230504 | 5187 | 0.119 | -0.0443 | No | ||
49 | GABBR1 | 2850519 2850735 | 5280 | 0.114 | -0.0487 | No | ||
50 | GMFB | 6590035 | 5327 | 0.111 | -0.0506 | No | ||
51 | LHX3 | 670164 1770280 | 5355 | 0.110 | -0.0515 | No | ||
52 | SH3BP4 | 3140242 | 5404 | 0.107 | -0.0536 | No | ||
53 | ARMC1 | 5220458 | 5467 | 0.104 | -0.0564 | No | ||
54 | DSCAM | 1780050 2450731 2810438 | 5471 | 0.103 | -0.0561 | No | ||
55 | HMGCLL1 | 2570091 | 5514 | 0.101 | -0.0578 | No | ||
56 | RASA1 | 1240315 | 5862 | 0.084 | -0.0763 | No | ||
57 | CLOCK | 1410070 2940292 3390075 | 5914 | 0.082 | -0.0786 | No | ||
58 | YWHAG | 3780341 | 6223 | 0.070 | -0.0950 | No | ||
59 | NTNG1 | 50270 1410427 4810333 | 6260 | 0.069 | -0.0966 | No | ||
60 | FGF9 | 1050195 | 6299 | 0.068 | -0.0983 | No | ||
61 | TXNL1 | 2850148 | 6362 | 0.065 | -0.1014 | No | ||
62 | HOXA10 | 6110397 7100458 | 6421 | 0.063 | -0.1042 | No | ||
63 | PRRX1 | 4120193 4480390 | 6431 | 0.063 | -0.1044 | No | ||
64 | RGS17 | 1400603 | 6491 | 0.061 | -0.1073 | No | ||
65 | ANK3 | 1500161 2900435 4210154 6400100 | 6654 | 0.056 | -0.1158 | No | ||
66 | RARG | 6760136 | 6697 | 0.055 | -0.1178 | No | ||
67 | ABLIM1 | 580170 3710338 6520504 | 6721 | 0.054 | -0.1187 | No | ||
68 | SCRT1 | 6760736 | 6815 | 0.052 | -0.1235 | No | ||
69 | EIF3S10 | 1190079 3840176 | 6975 | 0.048 | -0.1319 | No | ||
70 | FZD3 | 1500397 | 7023 | 0.047 | -0.1343 | No | ||
71 | PHF21A | 610014 | 7154 | 0.044 | -0.1411 | No | ||
72 | ACACA | 2490612 2680369 | 7206 | 0.043 | -0.1436 | No | ||
73 | EBF3 | 4200129 | 7231 | 0.042 | -0.1447 | No | ||
74 | FBXW7 | 4210338 7050280 | 7438 | 0.038 | -0.1557 | No | ||
75 | BRE | 2340273 3190731 4050500 | 7502 | 0.037 | -0.1590 | No | ||
76 | TOPBP1 | 6020333 | 7505 | 0.037 | -0.1589 | No | ||
77 | EFNB2 | 5340136 | 7812 | 0.031 | -0.1754 | No | ||
78 | BHLHB5 | 6510520 | 7933 | 0.029 | -0.1818 | No | ||
79 | SATB2 | 2470181 | 7951 | 0.028 | -0.1825 | No | ||
80 | BDNF | 2940128 3520368 | 7993 | 0.028 | -0.1846 | No | ||
81 | EPAS1 | 5290156 | 8237 | 0.023 | -0.1977 | No | ||
82 | STARD13 | 540722 | 8392 | 0.021 | -0.2060 | No | ||
83 | PCDH8 | 2360047 4200452 | 8530 | 0.018 | -0.2133 | No | ||
84 | PCDH18 | 430010 | 8687 | 0.016 | -0.2217 | No | ||
85 | BHLHB3 | 3450438 | 8696 | 0.015 | -0.2221 | No | ||
86 | MMP16 | 2680139 | 8729 | 0.015 | -0.2238 | No | ||
87 | NKX2-2 | 4150731 | 8814 | 0.013 | -0.2283 | No | ||
88 | ADAM10 | 3780156 | 8844 | 0.013 | -0.2298 | No | ||
89 | CITED2 | 5670114 5130088 | 9113 | 0.009 | -0.2443 | No | ||
90 | ANUBL1 | 1580113 | 9130 | 0.008 | -0.2451 | No | ||
91 | PLD1 | 2450537 | 9306 | 0.006 | -0.2546 | No | ||
92 | ADAMTS18 | 5690008 | 9408 | 0.004 | -0.2601 | No | ||
93 | CHES1 | 4570121 5700162 | 9641 | 0.001 | -0.2727 | No | ||
94 | ACVR1 | 6840671 | 9671 | 0.000 | -0.2743 | No | ||
95 | PTHLH | 5290739 | 9842 | -0.002 | -0.2835 | No | ||
96 | MTSS1 | 780435 2370114 | 9856 | -0.002 | -0.2842 | No | ||
97 | MAK | 2940706 | 10014 | -0.005 | -0.2927 | No | ||
98 | ARF4 | 3190661 | 10111 | -0.006 | -0.2979 | No | ||
99 | JUB | 5860711 5900500 | 10150 | -0.007 | -0.2999 | No | ||
100 | IGSF3 | 6450524 | 10165 | -0.007 | -0.3006 | No | ||
101 | IBRDC2 | 5130041 | 10181 | -0.007 | -0.3014 | No | ||
102 | BRUNOL6 | 6840373 | 10234 | -0.008 | -0.3042 | No | ||
103 | CCNJ | 870047 | 10319 | -0.009 | -0.3087 | No | ||
104 | ELMO1 | 110338 1190451 1580148 1850609 2350706 2370369 2450129 3840113 4150184 4280079 6290066 6380435 6770494 7100180 | 10479 | -0.011 | -0.3173 | No | ||
105 | ZMPSTE24 | 1090112 2030593 3780129 4590044 | 10589 | -0.013 | -0.3232 | No | ||
106 | BCL2L12 | 5360176 | 10686 | -0.015 | -0.3283 | No | ||
107 | SUHW2 | 5290192 | 10725 | -0.015 | -0.3303 | No | ||
108 | PAFAH1B1 | 4230333 6420121 6450066 | 10756 | -0.016 | -0.3319 | No | ||
109 | ELL2 | 6420091 | 10848 | -0.017 | -0.3367 | No | ||
110 | CD2AP | 1940369 | 10862 | -0.017 | -0.3373 | No | ||
111 | EPHB1 | 4610056 | 10903 | -0.018 | -0.3394 | No | ||
112 | SP3 | 3840338 | 10924 | -0.018 | -0.3404 | No | ||
113 | EPHA7 | 1190288 4010278 | 11012 | -0.020 | -0.3450 | No | ||
114 | SLC1A2 | 2230520 | 11148 | -0.022 | -0.3523 | No | ||
115 | ANK2 | 6510546 | 11263 | -0.024 | -0.3583 | No | ||
116 | RIMS3 | 3890563 | 11473 | -0.028 | -0.3696 | No | ||
117 | FMR1 | 5050075 | 11491 | -0.028 | -0.3703 | No | ||
118 | MITF | 380056 | 11505 | -0.028 | -0.3709 | No | ||
119 | VLDLR | 870722 3060047 5340452 6550131 | 11555 | -0.029 | -0.3734 | No | ||
120 | APLN | 6620632 | 11566 | -0.029 | -0.3738 | No | ||
121 | LPHN2 | 4480010 | 11655 | -0.031 | -0.3784 | No | ||
122 | ZCCHC14 | 5900288 | 11806 | -0.034 | -0.3864 | No | ||
123 | NPM1 | 4730427 | 11866 | -0.036 | -0.3894 | No | ||
124 | FBXW11 | 6450632 | 11951 | -0.037 | -0.3938 | No | ||
125 | TMEM47 | 1660086 | 12125 | -0.041 | -0.4030 | No | ||
126 | CTTN | 780154 1690538 3310017 4060717 | 12129 | -0.041 | -0.4030 | No | ||
127 | AKAP7 | 4610044 | 12155 | -0.042 | -0.4041 | No | ||
128 | BNC2 | 4810603 | 12219 | -0.044 | -0.4073 | No | ||
129 | ATOH8 | 4540204 | 12385 | -0.047 | -0.4160 | No | ||
130 | MEF2C | 670025 780338 | 12428 | -0.048 | -0.4181 | No | ||
131 | PRPF4B | 940181 2570300 | 12561 | -0.052 | -0.4250 | No | ||
132 | FOXF2 | 1240091 | 12638 | -0.054 | -0.4288 | No | ||
133 | KLF15 | 4230164 | 12783 | -0.059 | -0.4364 | No | ||
134 | PRDM1 | 3170347 3520301 | 12786 | -0.059 | -0.4362 | No | ||
135 | L1CAM | 4850021 | 12795 | -0.059 | -0.4363 | No | ||
136 | DR1 | 5860750 | 13020 | -0.067 | -0.4481 | No | ||
137 | ADCY2 | 4610100 | 13044 | -0.067 | -0.4490 | No | ||
138 | GRINL1A | 6350128 | 13058 | -0.068 | -0.4494 | No | ||
139 | RET | 3850746 | 13225 | -0.075 | -0.4580 | No | ||
140 | NPTX1 | 3710736 | 13357 | -0.081 | -0.4647 | No | ||
141 | ISL1 | 4810239 | 13435 | -0.085 | -0.4685 | No | ||
142 | EIF5 | 6380750 | 13457 | -0.086 | -0.4692 | No | ||
143 | ARHGEF7 | 1690441 | 13544 | -0.090 | -0.4734 | No | ||
144 | EPM2A | 2640079 | 13598 | -0.093 | -0.4758 | No | ||
145 | SOX2 | 630487 2230491 | 13639 | -0.095 | -0.4775 | No | ||
146 | CUL5 | 450142 | 13653 | -0.096 | -0.4777 | No | ||
147 | NAP1L1 | 2510593 5900215 5090470 450079 4920280 | 13732 | -0.101 | -0.4814 | No | ||
148 | ADRA2C | 5130154 | 13767 | -0.104 | -0.4827 | No | ||
149 | GRM5 | 60528 | 13784 | -0.105 | -0.4831 | No | ||
150 | SLITRK4 | 5910022 | 13956 | -0.117 | -0.4918 | No | ||
151 | BTBD11 | 6650154 | 13973 | -0.119 | -0.4920 | No | ||
152 | PDZD4 | 840528 6290438 6350044 | 14050 | -0.125 | -0.4955 | No | ||
153 | BRMS1L | 6110609 | 14095 | -0.128 | -0.4973 | No | ||
154 | RDX | 4200039 6550465 | 14157 | -0.135 | -0.4999 | No | ||
155 | PRKD1 | 1410706 5090438 | 14172 | -0.136 | -0.4999 | No | ||
156 | RAB6B | 5860121 | 14194 | -0.138 | -0.5004 | No | ||
157 | KHDRBS3 | 2120154 | 14463 | -0.165 | -0.5141 | No | ||
158 | PAIP2 | 4210441 | 14590 | -0.179 | -0.5200 | No | ||
159 | NUMB | 2450735 3800253 6350040 | 14614 | -0.184 | -0.5203 | No | ||
160 | BCL2L13 | 3170593 | 14751 | -0.204 | -0.5267 | No | ||
161 | XPR1 | 1500093 | 14812 | -0.217 | -0.5288 | No | ||
162 | GPR85 | 5130750 5910020 | 14879 | -0.230 | -0.5312 | No | ||
163 | EXOC4 | 2470253 | 14959 | -0.249 | -0.5343 | No | ||
164 | MYADM | 4230132 | 14962 | -0.250 | -0.5331 | No | ||
165 | MMD | 3850239 | 15200 | -0.307 | -0.5444 | No | ||
166 | MEF2D | 5690576 | 15207 | -0.312 | -0.5431 | No | ||
167 | VAV2 | 3610725 5890717 | 15209 | -0.312 | -0.5416 | No | ||
168 | PIGA | 1940435 5290692 | 15487 | -0.403 | -0.5546 | No | ||
169 | OGT | 2360131 4610333 | 15489 | -0.403 | -0.5526 | No | ||
170 | DOK4 | 4060452 | 15636 | -0.463 | -0.5581 | No | ||
171 | SLC39A9 | 3940348 | 15639 | -0.464 | -0.5558 | No | ||
172 | BAG4 | 2260070 | 15685 | -0.492 | -0.5558 | No | ||
173 | ABCC3 | 4050242 | 15739 | -0.518 | -0.5560 | No | ||
174 | KTN1 | 70446 3450609 4560048 | 15838 | -0.560 | -0.5584 | No | ||
175 | SLC4A7 | 2370056 | 15867 | -0.579 | -0.5570 | No | ||
176 | SPRY4 | 1570594 | 16148 | -0.736 | -0.5684 | Yes | ||
177 | SYPL1 | 2680706 5900403 | 16198 | -0.770 | -0.5672 | Yes | ||
178 | PPP1R2 | 3710278 1400725 | 16299 | -0.837 | -0.5683 | Yes | ||
179 | VASP | 7050500 | 16343 | -0.863 | -0.5662 | Yes | ||
180 | MARCKS | 7040450 | 16376 | -0.885 | -0.5634 | Yes | ||
181 | MAGI1 | 6510500 1990239 4670471 | 16410 | -0.903 | -0.5606 | Yes | ||
182 | PCMT1 | 4590338 4590541 | 16489 | -0.954 | -0.5599 | Yes | ||
183 | PRKACB | 4210170 | 16551 | -0.996 | -0.5581 | Yes | ||
184 | RAB10 | 2360008 5890020 | 16665 | -1.054 | -0.5588 | Yes | ||
185 | ELL | 3520731 | 16673 | -1.063 | -0.5538 | Yes | ||
186 | ZFP36L1 | 2510138 4120048 | 16675 | -1.064 | -0.5484 | Yes | ||
187 | AEBP2 | 2970603 | 16681 | -1.066 | -0.5432 | Yes | ||
188 | GIT2 | 6040039 6770181 | 16766 | -1.141 | -0.5419 | Yes | ||
189 | ADD3 | 4150739 5390600 | 16818 | -1.184 | -0.5386 | Yes | ||
190 | ATXN1 | 5550156 | 16822 | -1.187 | -0.5326 | Yes | ||
191 | MTCH2 | 3780603 6620215 | 16826 | -1.189 | -0.5267 | Yes | ||
192 | WDR40A | 2190167 | 16830 | -1.190 | -0.5208 | Yes | ||
193 | MFAP3 | 6380066 6520487 | 16909 | -1.257 | -0.5186 | Yes | ||
194 | BCL2 | 730132 1570736 2470138 3800044 4810037 5690068 5860504 6650164 | 16927 | -1.270 | -0.5130 | Yes | ||
195 | FEM1C | 60300 6130717 6980164 | 16931 | -1.273 | -0.5066 | Yes | ||
196 | KCMF1 | 2970577 | 17008 | -1.352 | -0.5038 | Yes | ||
197 | ARHGDIA | 5900239 | 17076 | -1.447 | -0.5000 | Yes | ||
198 | WSB1 | 870563 | 17148 | -1.535 | -0.4960 | Yes | ||
199 | TAF15 | 4120736 | 17166 | -1.549 | -0.4890 | Yes | ||
200 | BCL11A | 6860369 | 17185 | -1.577 | -0.4819 | Yes | ||
201 | PHF13 | 450435 | 17574 | -2.159 | -0.4919 | Yes | ||
202 | DYNC1LI2 | 50338 | 17666 | -2.358 | -0.4847 | Yes | ||
203 | CD47 | 1850603 | 17731 | -2.476 | -0.4755 | Yes | ||
204 | TRIM8 | 6130441 | 17757 | -2.538 | -0.4638 | Yes | ||
205 | MAP1LC3B | 730142 | 18059 | -3.296 | -0.4633 | Yes | ||
206 | TOB1 | 4150138 | 18066 | -3.318 | -0.4466 | Yes | ||
207 | KLF7 | 50390 | 18070 | -3.321 | -0.4297 | Yes | ||
208 | DOCK9 | 5080037 | 18119 | -3.508 | -0.4143 | Yes | ||
209 | WASF2 | 4850592 | 18159 | -3.677 | -0.3976 | Yes | ||
210 | BACH2 | 6760131 | 18172 | -3.712 | -0.3792 | Yes | ||
211 | IHPK1 | 1340053 | 18235 | -4.035 | -0.3618 | Yes | ||
212 | MARK3 | 2370450 | 18269 | -4.202 | -0.3420 | Yes | ||
213 | PBX2 | 3130433 6510292 | 18285 | -4.288 | -0.3209 | Yes | ||
214 | DYRK1A | 3190181 | 18295 | -4.333 | -0.2991 | Yes | ||
215 | KLF13 | 4670563 | 18309 | -4.420 | -0.2771 | Yes | ||
216 | ZNRF1 | 70592 | 18315 | -4.452 | -0.2546 | Yes | ||
217 | XBP1 | 3840594 | 18340 | -4.607 | -0.2322 | Yes | ||
218 | UBE3C | 3140673 | 18354 | -4.694 | -0.2088 | Yes | ||
219 | RNF44 | 5910692 | 18480 | -5.836 | -0.1857 | Yes | ||
220 | FLOT1 | 1660575 1690040 | 18525 | -6.541 | -0.1545 | Yes | ||
221 | CSNK1E | 2850347 5050093 6110301 | 18544 | -6.919 | -0.1200 | Yes | ||
222 | ETS2 | 360451 | 18547 | -6.975 | -0.0843 | Yes | ||
223 | SH2D1A | 4760025 | 18590 | -8.396 | -0.0435 | Yes | ||
224 | ZFP36 | 2030605 | 18601 | -8.743 | 0.0008 | Yes |