Details for gene set TGCACTT,MIR-519C,MIR-519B,MIR-519A[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos
Phenotype	phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	TGCACTT,MIR-519C,MIR-519B,MIR-519A
Enrichment Score (ES)	-0.5840863
Normalized Enrichment Score (NES)	-1.6602108
Nominal p-value	0.0
FDR q-value	0.06460916
FWER p-Value	0.128

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	DDX3X	2190020	681	2.564	-0.0261	No
2	DAZAP2	6200102	998	2.034	-0.0346	No
3	YTHDF2	4060332 4610279	1062	1.955	-0.0296	No
4	AHCTF1	7040100	1127	1.883	-0.0249	No
5	CUL3	1850520	1147	1.860	-0.0179	No
6	SFMBT1	2360450 2370070	1372	1.654	-0.0230	No
7	E2F1	5360093	1632	1.410	-0.0311	No
8	FJX1	3390035	1649	1.395	-0.0259	No
9	SFRS2	50707 380593	1695	1.356	-0.0225	No
10	KIF23	5570112	1714	1.341	-0.0177	No
11	DDX11	6590671	1760	1.298	-0.0145	No
12	HABP4	840487	1855	1.231	-0.0143	No
13	PIGS	3610142	1882	1.204	-0.0106	No
14	SMOC2	1170170	1909	1.178	-0.0069	No
15	TGFBR2	1780711 1980537 6550398	2076	1.050	-0.0114	No
16	CNOT7	2450338 5720397	2182	0.999	-0.0128	No
17	DPYSL2	2100427 3130112 5700324	2183	0.999	-0.0085	No
18	ACTL6A	5220543 6290541 2450093 4590332 5270722	2215	0.990	-0.0059	No
19	SUV39H1	630112	2261	0.973	-0.0042	No
20	ABHD2	4850504 6840010	2279	0.959	-0.0010	No
21	ASF1A	7050020	2280	0.959	0.0032	No
22	MCM7	3290292 5220056	2495	0.823	-0.0050	No
23	CELSR2	2320148 6220152	2520	0.808	-0.0028	No
24	MIB1	3800537	2547	0.789	-0.0008	No
25	PHTF2	6590053	2559	0.782	0.0020	No
26	BLCAP	3990253	2618	0.749	0.0021	No
27	GNS	3120458	2802	0.659	-0.0051	No
28	MBNL1	2640762 7100048	2866	0.634	-0.0058	No
29	CRSP2	1940059	2885	0.625	-0.0041	No
30	LIMK1	5080064	2894	0.620	-0.0018	No
31	KLF9	3840022	2941	0.597	-0.0017	No
32	ANKFY1	360309 5390021	3004	0.572	-0.0027	No
33	CUGBP2	6180121 6840139	3053	0.553	-0.0029	No
34	TIMP2	4780609	3195	0.500	-0.0084	No
35	RBBP6	2320129	3246	0.481	-0.0091	No
36	PCDHA7	1850019	3251	0.479	-0.0072	No
37	TOPORS	4060592	3313	0.454	-0.0086	No
38	PFN2	730040 5700026	3328	0.450	-0.0074	No
39	NFAT5	2510411 5890195 6550152	3369	0.441	-0.0077	No
40	ERBB2IP	580253 1090672	3449	0.410	-0.0102	No
41	LAPTM4A	450092	3551	0.375	-0.0141	No
42	KPNA3	7040088	3572	0.369	-0.0136	No
43	UBE3A	1240152 2690438 5860609	3605	0.355	-0.0139	No
44	PKIA	4070441	3615	0.350	-0.0128	No
45	BRWD1	3130048 3140168 6400601	3631	0.344	-0.0122	No
46	MTMR4	4540524	3680	0.329	-0.0134	No
47	STC1	360161	3684	0.328	-0.0121	No
48	EPC2	2470095	3689	0.326	-0.0109	No
49	PPP3CA	4760332 6760092	3702	0.323	-0.0102	No
50	MOBKL2B	940128	3736	0.312	-0.0106	No
51	CPEB2	4760338	3872	0.282	-0.0168	No
52	THRA	6770341 110164 1990600	3910	0.274	-0.0176	No
53	RYR3	1660156	3931	0.269	-0.0176	No
54	NPAS2	770670	3940	0.267	-0.0168	No
55	TNFRSF21	6380100	3992	0.253	-0.0185	No
56	SNX16	870446	3996	0.253	-0.0176	No
57	FASTK	2690053 4280288 4610551 6370292	4077	0.239	-0.0209	No
58	POLQ	1050053 2190102	4099	0.235	-0.0211	No
59	NEUROG2	5420278	4200	0.218	-0.0256	No
60	KCND2	1170128 2100112	4236	0.212	-0.0266	No
61	ST8SIA2	2680082	4267	0.208	-0.0273	No
62	ACSL4	510020 1240041 3190050 4540500 5570463	4352	0.198	-0.0311	No
63	EIF4G2	3800575 6860184	4422	0.188	-0.0340	No
64	NPAT	3800594 4670026	4488	0.181	-0.0368	No
65	L3MBTL3	3800113 6660068	4645	0.163	-0.0446	No
66	EIF2C1	6900551	4650	0.163	-0.0441	No
67	EFNB1	2970433	4725	0.156	-0.0475	No
68	SOX21	1050110 4670041 6660338	4840	0.146	-0.0531	No
69	ARID4B	730754 6660026	4844	0.145	-0.0526	No
70	RASD1	2450463	4877	0.142	-0.0537	No
71	IGF1	1990193 3130377 3290280	4888	0.141	-0.0537	No
72	NBL1	2480021	4997	0.131	-0.0590	No
73	PDGFRA	2940332	5000	0.131	-0.0586	No
74	QKI	5220093 6130044	5026	0.130	-0.0594	No
75	ARID4A	520156 1050707	5087	0.126	-0.0621	No
76	FBXL5	510088 770075 2970309	5109	0.125	-0.0627	No
77	SYN2	3990593	5121	0.124	-0.0628	No
78	NR1D1	2360471 770746 6590204	5147	0.122	-0.0636	No
79	RAP2C	1690132	5324	0.111	-0.0727	No
80	TESK2	6520524	5325	0.111	-0.0722	No
81	TRIM3	5570156	5367	0.109	-0.0740	No
82	HOXA3	3610632 6020358	5397	0.107	-0.0751	No
83	HOXB3	520292	5445	0.105	-0.0773	No
84	PLCB1	2570050 7100102	5457	0.104	-0.0774	No
85	FSTL5	770280	5487	0.102	-0.0785	No
86	COL4A3	5910075	5555	0.099	-0.0818	No
87	SLITRK3	5910041	5708	0.092	-0.0897	No
88	DDX5	940021 2630338 3440148	5753	0.089	-0.0917	No
89	LRCH2	2900162	5855	0.084	-0.0968	No
90	KCNQ2	130204 290291 5860132	5908	0.083	-0.0993	No
91	NRP2	4070400 5860041 6650446	5980	0.079	-0.1029	No
92	DUSP8	6650039	6111	0.074	-0.1096	No
93	HIVEP2	6520538	6129	0.074	-0.1103	No
94	PCDHA1	940026 540484	6143	0.073	-0.1106	No
95	ROCK2	1780035 5720025	6168	0.072	-0.1116	No
96	FGF9	1050195	6299	0.068	-0.1185	No
97	STK38	7100114	6306	0.067	-0.1185	No
98	HMGA2	2940121 3390647 5130279 6400136	6308	0.067	-0.1183	No
99	BMPR2	5340066 6960328	6413	0.064	-0.1237	No
100	NFIA	2760129 5860278	6418	0.063	-0.1236	No
101	PKD2	4670390	6489	0.061	-0.1272	No
102	PTGFRN	4120524	6582	0.058	-0.1319	No
103	PRKAA1	510156	6589	0.058	-0.1320	No
104	KCNJ10	2260577	6652	0.056	-0.1352	No
105	HAS2	5360181	6744	0.054	-0.1399	No
106	DNAJB6	2810309 5570451	6772	0.053	-0.1411	No
107	MAP3K9	3290707	6885	0.050	-0.1470	No
108	GDA	3290435	6896	0.050	-0.1474	No
109	NHLH2	6200021	6928	0.049	-0.1488	No
110	ZBTB4	6450441	7042	0.046	-0.1548	No
111	MAPRE3	7050504	7047	0.046	-0.1548	No
112	DNAJB9	460114	7132	0.044	-0.1592	No
113	PIK3R1	4730671	7165	0.043	-0.1608	No
114	ASXL2	130670	7193	0.043	-0.1621	No
115	WDFY3	3610041 4560333 4570273	7220	0.042	-0.1633	No
116	USP15	610592 3520504	7252	0.042	-0.1648	No
117	RTN1	4150452 4850176	7324	0.040	-0.1685	No
118	TNKS1BP1	7040184	7431	0.038	-0.1742	No
119	KLF11	6840739	7586	0.035	-0.1824	No
120	GOPC	6620400	7838	0.031	-0.1960	No
121	ATRN	870735 3360390	7994	0.028	-0.2043	No
122	EMX2	1660092	8031	0.027	-0.2062	No
123	TEAD1	2470551	8128	0.025	-0.2113	No
124	ARHGAP12	1050181	8221	0.023	-0.2163	No
125	PCDHA3	3840402	8225	0.023	-0.2163	No
126	MASTL	380433 4480215 5390301	8338	0.022	-0.2223	No
127	WDR20	1240373	8360	0.021	-0.2234	No
128	NHLH1	6100452	8458	0.019	-0.2286	No
129	CALD1	1770129 1940397	8546	0.018	-0.2333	No
130	PCDH20	4200576	8566	0.017	-0.2342	No
131	NEUROG1	380341	8575	0.017	-0.2346	No
132	MYT1	6770524	8683	0.016	-0.2404	No
133	SHANK2	1500452	8684	0.016	-0.2403	No
134	BTG3	7050079	8689	0.016	-0.2405	No
135	BHLHB3	3450438	8696	0.015	-0.2407	No
136	SMAD7	430377	8801	0.014	-0.2463	No
137	PCDHA10	3830725	8973	0.011	-0.2556	No
138	ZFPM2	460072	9001	0.010	-0.2571	No
139	PTPN2	130315	9053	0.009	-0.2598	No
140	ANUBL1	1580113	9130	0.008	-0.2639	No
141	SERTAD2	2810673 6840450	9200	0.007	-0.2677	No
142	SNX5	1570021 6860609	9426	0.004	-0.2799	No
143	HMGB3	2940168	9465	0.003	-0.2820	No
144	KIAA1715	1190551	9507	0.003	-0.2842	No
145	ACVR1	6840671	9671	0.000	-0.2931	No
146	HOXD8	3710156	9722	-0.000	-0.2959	No
147	PTHLH	5290739	9842	-0.002	-0.3023	No
148	YES1	6100050	9864	-0.002	-0.3035	No
149	MAPK4	870142	9905	-0.003	-0.3057	No
150	RAPGEF4	6100563	10117	-0.006	-0.3172	No
151	DCBLD2	5890333	10232	-0.008	-0.3233	No
152	BIRC6	70148	10241	-0.008	-0.3238	No
153	BTBD7	730288	10256	-0.008	-0.3245	No
154	PCDHA5	2970347	10288	-0.009	-0.3261	No
155	CCNJ	870047	10319	-0.009	-0.3277	No
156	TBX3	2570672	10330	-0.009	-0.3282	No
157	WNK3	4060053	10427	-0.011	-0.3334	No
158	PTPN4	1410047	10433	-0.011	-0.3337	No
159	HIF1A	5670605	10446	-0.011	-0.3343	No
160	PCDHA12	2810215	10590	-0.013	-0.3420	No
161	HEY2	3990504	10646	-0.014	-0.3450	No
162	COL19A1	6220441	10649	-0.014	-0.3450	No
163	PAFAH1B1	4230333 6420121 6450066	10756	-0.016	-0.3507	No
164	DDX3Y	1580278 4200519	10904	-0.018	-0.3587	No
165	SP3	3840338	10924	-0.018	-0.3596	No
166	MAP3K12	2470373 6420162	10936	-0.019	-0.3602	No
167	ABHD3	2370091	10947	-0.019	-0.3606	No
168	SLC24A4	2100487	10963	-0.019	-0.3614	No
169	EREG	50519 4920129	10971	-0.019	-0.3617	No
170	TNFSF12	1940465	11023	-0.020	-0.3644	No
171	SLC1A2	2230520	11148	-0.022	-0.3710	No
172	ANKRD29	1450112	11295	-0.025	-0.3789	No
173	ZFHX4	6110167	11311	-0.025	-0.3796	No
174	TNRC6A	1240537 6130037 6200010	11401	-0.027	-0.3844	No
175	VLDLR	870722 3060047 5340452 6550131	11555	-0.029	-0.3926	No
176	NKIRAS1	2510440 5570671	11571	-0.030	-0.3933	No
177	FAM60A	3940092	11590	-0.030	-0.3941	No
178	HIF1AN	2320309	11662	-0.031	-0.3979	No
179	CREB5	2320368	11678	-0.032	-0.3986	No
180	MAB21L1	1450634 1580092	11938	-0.037	-0.4126	No
181	FBXW11	6450632	11951	-0.037	-0.4130	No
182	PCDHA11	1510253	12203	-0.043	-0.4266	No
183	BNC2	4810603	12219	-0.044	-0.4272	No
184	M6PR	2480458 3290593 3840324	12249	-0.044	-0.4286	No
185	FOXA1	3710609	12503	-0.050	-0.4422	No
186	NF1	6980433	12559	-0.052	-0.4450	No
187	PCDHA6	780333 2370280	12619	-0.054	-0.4480	No
188	FOXF2	1240091	12638	-0.054	-0.4487	No
189	SYT1	840364	12644	-0.055	-0.4487	No
190	PAPOLA	4200286 4850112	12676	-0.055	-0.4502	No
191	PTPRT	6620433	12960	-0.065	-0.4654	No
192	PGM2L1	2350035	12985	-0.066	-0.4664	No
193	WEE1	3390070	13037	-0.067	-0.4689	No
194	RORB	6400035	13067	-0.068	-0.4702	No
195	ZFYVE9	6980288 7100017	13178	-0.073	-0.4759	No
196	ZDHHC1	3870035	13180	-0.073	-0.4756	No
197	ERBB4	4610400 4810017	13448	-0.085	-0.4898	No
198	VANGL1	380162	13453	-0.086	-0.4897	No
199	KLF12	1660095 4810288 5340546 6520286	13492	-0.087	-0.4914	No
200	STYX	1090358	13566	-0.091	-0.4950	No
201	KCNN2	990025 3520524	13578	-0.091	-0.4952	No
202	SUMF1	730050	13650	-0.096	-0.4986	No
203	MAP3K2	380270	13712	-0.100	-0.5015	No
204	R3HDM1	940685 3290161	13761	-0.104	-0.5037	No
205	GRM7	4230110	13782	-0.105	-0.5044	No
206	TNFSF11	6350204	13819	-0.107	-0.5059	No
207	MAP3K5	6020041 6380162	13822	-0.108	-0.5055	No
208	CSNK1G1	840082 1230575 3940647	13886	-0.112	-0.5085	No
209	SASH1	4070270	13899	-0.113	-0.5086	No
210	RFX3	520121 4280519 5570519 6100184	13915	-0.114	-0.5089	No
211	LMX1A	2810239 5690324	14024	-0.122	-0.5143	No
212	BRMS1L	6110609	14095	-0.128	-0.5176	No
213	EPHA4	460750	14117	-0.130	-0.5182	No
214	EFTUD1	5360736	14137	-0.132	-0.5186	No
215	CNOT4	2320242 6760706	14209	-0.140	-0.5219	No
216	RTN2	4480538	14219	-0.140	-0.5218	No
217	SOX5	2370576 2900167 3190128 5050528	14330	-0.152	-0.5271	No
218	ZHX2	2900452	14331	-0.152	-0.5265	No
219	SNRK	630021 2030731 6350017	14407	-0.159	-0.5299	No
220	PARD6B	4120600	14559	-0.174	-0.5374	No
221	ATP2C1	2630446 6520253	14694	-0.195	-0.5439	No
222	PANX2	7560121	14716	-0.199	-0.5442	No
223	SOCS6	1170347 7100280	14732	-0.201	-0.5441	No
224	DNM2	50176 3170279	14772	-0.208	-0.5453	No
225	NIPA1	380600	14775	-0.209	-0.5445	No
226	CACNB1	2940427 3710487	14831	-0.221	-0.5466	No
227	PLEKHA3	5080068	14863	-0.226	-0.5473	No
228	TRIOBP	940750 1300187 3140072	14868	-0.227	-0.5465	No
229	LAMP2	1230402 1980373	14876	-0.229	-0.5459	No
230	KIF5A	510435	15009	-0.260	-0.5520	No
231	SMAD5	5700497	15143	-0.288	-0.5580	No
232	SH3BP5	7100408	15208	-0.312	-0.5602	No
233	ARHGAP1	2810010 5270064	15228	-0.319	-0.5598	No
234	BCL2L2	2760692 6770739	15246	-0.324	-0.5594	No
235	CHD9	430037 2570129 5420398	15277	-0.333	-0.5596	No
236	PIGA	1940435 5290692	15487	-0.403	-0.5692	No
237	OGT	2360131 4610333	15489	-0.403	-0.5676	No
238	LACE1	1410079	15750	-0.522	-0.5795	No
239	VAMP4	4150102	15835	-0.559	-0.5817	Yes
240	RKHD1	6860577	15837	-0.560	-0.5793	Yes
241	E2F7	4200056	15843	-0.563	-0.5771	Yes
242	SCAMP2	430114	15854	-0.570	-0.5752	Yes
243	SLC4A7	2370056	15867	-0.579	-0.5734	Yes
244	PURB	5360138	15929	-0.615	-0.5741	Yes
245	NFIX	2450152	15956	-0.631	-0.5727	Yes
246	AKT3	1580270 3290278	15967	-0.634	-0.5706	Yes
247	GOLGA1	5860471	15974	-0.641	-0.5681	Yes
248	CFL2	380239 6200368	16022	-0.663	-0.5678	Yes
249	SPRY4	1570594	16148	-0.736	-0.5715	Yes
250	TAF5L	5690152	16182	-0.759	-0.5700	Yes
251	MAP3K8	2940286	16231	-0.789	-0.5692	Yes
252	TBL1X	6400524	16268	-0.814	-0.5676	Yes
253	RAB5B	130397 1980273 6900731	16275	-0.819	-0.5644	Yes
254	MAPRE1	3290037	16292	-0.831	-0.5617	Yes
255	BICD2	1090411	16428	-0.913	-0.5651	Yes
256	RNF31	110035	16488	-0.954	-0.5642	Yes
257	HBP1	2510102 3130010 4210619	16575	-1.003	-0.5646	Yes
258	MAPK6	6760520	16592	-1.010	-0.5611	Yes
259	RAB10	2360008 5890020	16665	-1.054	-0.5605	Yes
260	SKI	6590008	16688	-1.077	-0.5570	Yes
261	MYB	1660494 5860451 6130706	16734	-1.112	-0.5547	Yes
262	CRKRS	510537 2510551	16752	-1.127	-0.5507	Yes
263	MECP2	1940450	16762	-1.137	-0.5463	Yes
264	SFRS5	3450176 6350008	16788	-1.161	-0.5427	Yes
265	SOX4	2260091	17066	-1.434	-0.5516	Yes
266	CDK2	130484 2260301 4010088 5050110	17116	-1.496	-0.5478	Yes
267	SSH2	360056	17136	-1.523	-0.5422	Yes
268	STK17B	130091	17146	-1.532	-0.5361	Yes
269	ADIPOR2	1510035	17152	-1.536	-0.5298	Yes
270	SLC40A1	2370286	17186	-1.579	-0.5247	Yes
271	ITCH	1410731 5700022	17241	-1.653	-0.5205	Yes
272	RB1	5900338	17268	-1.683	-0.5147	Yes
273	ELK3	460377 1400762 3710497	17322	-1.738	-0.5101	Yes
274	TSG101	770148	17360	-1.802	-0.5043	Yes
275	PIK4CB	510450 1780452	17500	-2.031	-0.5031	Yes
276	PKNOX1	4210452	17526	-2.079	-0.4955	Yes
277	PPP1R10	110136 3170725 3610484	17533	-2.092	-0.4868	Yes
278	SNIP1	5360092	17536	-2.095	-0.4778	Yes
279	ITPR1	3450519	17548	-2.119	-0.4693	Yes
280	ARHGAP24	540278 4540025	17594	-2.202	-0.4622	Yes
281	GOSR1	730279	17595	-2.203	-0.4527	Yes
282	ENPP5	1780338	17598	-2.205	-0.4433	Yes
283	HECA	3310612	17645	-2.320	-0.4358	Yes
284	ARHGEF11	1780288	17766	-2.559	-0.4312	Yes
285	RAD52	110093	17787	-2.602	-0.4211	Yes
286	STX6	4850750 6770278	17794	-2.615	-0.4101	Yes
287	ZDHHC9	3940204	17851	-2.740	-0.4013	Yes
288	USP3	2060332	17858	-2.751	-0.3898	Yes
289	ATG16L1	5390292	17931	-2.941	-0.3810	Yes
290	SEMA4B	110347	18044	-3.235	-0.3731	Yes
291	CASP2	2260692	18065	-3.311	-0.3599	Yes
292	STAT3	460040 3710341	18169	-3.701	-0.3495	Yes
293	NAGK	730041 3170086 5890053	18178	-3.746	-0.3338	Yes
294	KBTBD2	2320014	18252	-4.125	-0.3199	Yes
295	CIC	6370161	18256	-4.145	-0.3022	Yes
296	DYRK1A	3190181	18295	-4.333	-0.2855	Yes
297	NDEL1	2370465	18364	-4.753	-0.2687	Yes
298	MAP3K3	610685	18366	-4.757	-0.2482	Yes
299	ANKRD50	870543	18370	-4.795	-0.2276	Yes
300	GTPBP2	2760750	18462	-5.667	-0.2081	Yes
301	SORL1	630204	18493	-5.965	-0.1840	Yes
302	MAML1	2760008	18494	-5.971	-0.1582	Yes
303	MMP14	670079	18528	-6.578	-0.1315	Yes
304	WDR1	1090129 3990121	18543	-6.863	-0.1026	Yes
305	LRRIQ2	3990064 6370673 6380372	18557	-7.213	-0.0722	Yes
306	LRIG1	1050136	18597	-8.598	-0.0371	Yes
307	SMOC1	840039	18602	-8.820	0.0008	Yes