Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
| Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | GCACCTT,MIR-18A,MIR-18B |
| Enrichment Score (ES) | -0.70105433 |
| Normalized Enrichment Score (NES) | -1.718443 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.05533459 |
| FWER p-Value | 0.038 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | PHF19 | 3800358 | 233 | 3.873 | 0.0357 | No | ||
| 2 | TEX2 | 1740504 2480102 3060494 | 1448 | 1.587 | -0.0099 | No | ||
| 3 | PARP6 | 3290332 4760167 6900181 | 2415 | 0.873 | -0.0512 | No | ||
| 4 | CDC42 | 1240168 3440278 4480519 5290162 | 2599 | 0.760 | -0.0515 | No | ||
| 5 | NR3C1 | 630563 | 3096 | 0.540 | -0.0716 | No | ||
| 6 | NFAT5 | 2510411 5890195 6550152 | 3369 | 0.441 | -0.0807 | No | ||
| 7 | PIAS3 | 50204 240739 4060524 | 3886 | 0.279 | -0.1051 | No | ||
| 8 | TARDBP | 870390 2350093 | 3982 | 0.257 | -0.1070 | No | ||
| 9 | ARL15 | 6520692 | 4403 | 0.191 | -0.1273 | No | ||
| 10 | SOCS5 | 3830398 7100093 | 4608 | 0.167 | -0.1362 | No | ||
| 11 | IGF1 | 1990193 3130377 3290280 | 4888 | 0.141 | -0.1495 | No | ||
| 12 | SON | 3120148 5860239 7040403 | 4954 | 0.136 | -0.1513 | No | ||
| 13 | HSF2 | 1400465 | 5201 | 0.118 | -0.1631 | No | ||
| 14 | PRICKLE2 | 780408 | 5233 | 0.117 | -0.1633 | No | ||
| 15 | SH3BP4 | 3140242 | 5404 | 0.107 | -0.1711 | No | ||
| 16 | ESR1 | 4060372 5860193 | 5420 | 0.106 | -0.1706 | No | ||
| 17 | MESP1 | 4280673 | 5436 | 0.105 | -0.1701 | No | ||
| 18 | EHMT1 | 5290433 5910086 6620112 6980014 | 5454 | 0.104 | -0.1697 | No | ||
| 19 | RABGAP1 | 5050397 | 5542 | 0.100 | -0.1732 | No | ||
| 20 | RAB11FIP2 | 4570040 | 5645 | 0.095 | -0.1775 | No | ||
| 21 | AKR1D1 | 6770026 | 5875 | 0.084 | -0.1888 | No | ||
| 22 | PTGFRN | 4120524 | 6582 | 0.058 | -0.2262 | No | ||
| 23 | CTGF | 4540577 | 6689 | 0.055 | -0.2312 | No | ||
| 24 | ZBTB4 | 6450441 | 7042 | 0.046 | -0.2496 | No | ||
| 25 | ASXL2 | 130670 | 7193 | 0.043 | -0.2572 | No | ||
| 26 | DPP10 | 4730746 | 7392 | 0.039 | -0.2674 | No | ||
| 27 | LIN28 | 6590672 | 7537 | 0.036 | -0.2747 | No | ||
| 28 | BHLHB5 | 6510520 | 7933 | 0.029 | -0.2956 | No | ||
| 29 | BTG3 | 7050079 | 8689 | 0.016 | -0.3361 | No | ||
| 30 | ALCAM | 1050019 | 8961 | 0.011 | -0.3506 | No | ||
| 31 | TRIM2 | 430546 1170286 | 10028 | -0.005 | -0.4081 | No | ||
| 32 | SIM2 | 2100044 | 10368 | -0.010 | -0.4262 | No | ||
| 33 | HIF1A | 5670605 | 10446 | -0.011 | -0.4302 | No | ||
| 34 | GCLC | 2810731 | 12119 | -0.041 | -0.5199 | No | ||
| 35 | MAN1A2 | 5700435 5720114 | 12768 | -0.058 | -0.5541 | No | ||
| 36 | CLASP2 | 2510139 | 13645 | -0.096 | -0.6002 | No | ||
| 37 | NAV1 | 4210519 6620129 | 14351 | -0.154 | -0.6363 | No | ||
| 38 | GLRB | 2510433 4280736 | 14426 | -0.162 | -0.6383 | No | ||
| 39 | TRIOBP | 940750 1300187 3140072 | 14868 | -0.227 | -0.6592 | No | ||
| 40 | MDGA1 | 1170139 | 15106 | -0.280 | -0.6685 | No | ||
| 41 | MEF2D | 5690576 | 15207 | -0.312 | -0.6700 | No | ||
| 42 | CRIM1 | 130491 | 15400 | -0.368 | -0.6758 | No | ||
| 43 | FNBP1 | 6100017 | 15606 | -0.451 | -0.6812 | No | ||
| 44 | CTDSPL | 4670546 | 15704 | -0.499 | -0.6802 | No | ||
| 45 | RHOT1 | 6760692 | 15710 | -0.501 | -0.6742 | No | ||
| 46 | PURB | 5360138 | 15929 | -0.615 | -0.6783 | No | ||
| 47 | KIT | 7040095 | 16331 | -0.857 | -0.6892 | Yes | ||
| 48 | PRKACB | 4210170 | 16551 | -0.996 | -0.6886 | Yes | ||
| 49 | SNURF | 3520053 | 16572 | -1.002 | -0.6772 | Yes | ||
| 50 | PACSIN1 | 3870632 6370021 6900707 | 16628 | -1.026 | -0.6674 | Yes | ||
| 51 | SAR1A | 3450253 | 16669 | -1.058 | -0.6563 | Yes | ||
| 52 | ZFP36L1 | 2510138 4120048 | 16675 | -1.064 | -0.6433 | Yes | ||
| 53 | AEBP2 | 2970603 | 16681 | -1.066 | -0.6303 | Yes | ||
| 54 | SMAD2 | 4200592 | 16721 | -1.104 | -0.6186 | Yes | ||
| 55 | ADD3 | 4150739 5390600 | 16818 | -1.184 | -0.6090 | Yes | ||
| 56 | ATXN1 | 5550156 | 16822 | -1.187 | -0.5944 | Yes | ||
| 57 | FRMD4A | 2190176 | 16892 | -1.242 | -0.5826 | Yes | ||
| 58 | ETV6 | 610524 | 16961 | -1.305 | -0.5700 | Yes | ||
| 59 | WSB1 | 870563 | 17148 | -1.535 | -0.5609 | Yes | ||
| 60 | PERQ1 | 1340164 | 17172 | -1.554 | -0.5428 | Yes | ||
| 61 | FCHSD2 | 5720092 | 17198 | -1.593 | -0.5242 | Yes | ||
| 62 | NR1H2 | 4070056 | 17210 | -1.613 | -0.5047 | Yes | ||
| 63 | JARID1B | 4730494 | 17530 | -2.092 | -0.4958 | Yes | ||
| 64 | XYLT2 | 6380039 | 17596 | -2.203 | -0.4719 | Yes | ||
| 65 | RUNX1 | 3840711 | 17599 | -2.206 | -0.4445 | Yes | ||
| 66 | NCOA1 | 3610438 | 17669 | -2.367 | -0.4187 | Yes | ||
| 67 | STK4 | 2640152 | 17801 | -2.623 | -0.3930 | Yes | ||
| 68 | ARHGEF5 | 3170605 | 17872 | -2.781 | -0.3621 | Yes | ||
| 69 | RAB5C | 1990397 | 17941 | -2.964 | -0.3288 | Yes | ||
| 70 | GAB1 | 2970156 | 17961 | -2.990 | -0.2925 | Yes | ||
| 71 | CLK2 | 510079 2630736 | 18091 | -3.402 | -0.2571 | Yes | ||
| 72 | IRF2 | 5390044 | 18151 | -3.645 | -0.2148 | Yes | ||
| 73 | TRIB2 | 4120605 | 18192 | -3.802 | -0.1695 | Yes | ||
| 74 | NEDD9 | 1740373 4230053 | 18207 | -3.858 | -0.1222 | Yes | ||
| 75 | ANKRD50 | 870543 | 18370 | -4.795 | -0.0711 | Yes | ||
| 76 | PHF2 | 4060300 | 18540 | -6.759 | 0.0041 | Yes |
