Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | AGCACTT,MIR-93,MIR-302A,MIR-302B,MIR-302C,MIR-302D,MIR-372,MIR-373,MIR-520E,MIR-520A,MIR-526B,MIR-520B,MIR-520C,MIR-520D |
Enrichment Score (ES) | -0.5830625 |
Normalized Enrichment Score (NES) | -1.6122398 |
Nominal p-value | 0.0 |
FDR q-value | 0.07912083 |
FWER p-Value | 0.283 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | RBBP7 | 430113 450450 2370309 | 218 | 3.950 | 0.0053 | No | ||
2 | SLC6A9 | 2470520 | 426 | 3.130 | 0.0077 | No | ||
3 | SDC1 | 3440471 6350408 | 522 | 2.876 | 0.0150 | No | ||
4 | CCND1 | 460524 770309 3120576 6980398 | 547 | 2.823 | 0.0260 | No | ||
5 | RPS6KA1 | 4120647 | 789 | 2.372 | 0.0232 | No | ||
6 | TNFAIP1 | 6940593 | 795 | 2.359 | 0.0331 | No | ||
7 | DAZAP2 | 6200102 | 998 | 2.034 | 0.0310 | No | ||
8 | LEFTY1 | 3290452 | 1068 | 1.950 | 0.0357 | No | ||
9 | MBNL2 | 3450707 | 1087 | 1.929 | 0.0431 | No | ||
10 | APP | 2510053 | 1171 | 1.841 | 0.0466 | No | ||
11 | RGMA | 2450711 | 1267 | 1.740 | 0.0490 | No | ||
12 | INHBB | 2680092 | 1342 | 1.677 | 0.0523 | No | ||
13 | MRPS25 | 610441 870128 1410368 | 1672 | 1.374 | 0.0403 | No | ||
14 | RPS6KA3 | 1980707 | 1682 | 1.368 | 0.0458 | No | ||
15 | CXXC6 | 2810168 | 1766 | 1.296 | 0.0469 | No | ||
16 | AK2 | 4590458 4760195 6110097 | 1965 | 1.135 | 0.0411 | No | ||
17 | SS18L1 | 4610180 6550068 | 2072 | 1.051 | 0.0399 | No | ||
18 | PPP3R1 | 1190041 1570487 | 2170 | 1.000 | 0.0390 | No | ||
19 | MUTED | 3140452 4610086 4730348 | 2211 | 0.991 | 0.0411 | No | ||
20 | SUV39H1 | 630112 | 2261 | 0.973 | 0.0427 | No | ||
21 | ASF1A | 7050020 | 2280 | 0.959 | 0.0458 | No | ||
22 | TRIM36 | 1400600 1980082 5130037 | 2364 | 0.904 | 0.0453 | No | ||
23 | DCUN1D1 | 2360332 | 2382 | 0.893 | 0.0482 | No | ||
24 | PBX3 | 1300424 3710577 6180575 | 2438 | 0.857 | 0.0489 | No | ||
25 | RALGDS | 430463 | 2606 | 0.758 | 0.0432 | No | ||
26 | YWHAZ | 1230717 | 2671 | 0.728 | 0.0428 | No | ||
27 | NEK9 | 3440402 | 2703 | 0.710 | 0.0442 | No | ||
28 | UBE2J1 | 4070133 | 2771 | 0.670 | 0.0435 | No | ||
29 | YTHDF3 | 4540632 4670717 7040609 | 2861 | 0.636 | 0.0414 | No | ||
30 | TRPS1 | 870100 | 2983 | 0.579 | 0.0374 | No | ||
31 | CUGBP2 | 6180121 6840139 | 3053 | 0.553 | 0.0360 | No | ||
32 | RAB22A | 110500 3830707 | 3217 | 0.492 | 0.0293 | No | ||
33 | ADAM9 | 3360411 | 3243 | 0.484 | 0.0300 | No | ||
34 | PCDHA7 | 1850019 | 3251 | 0.479 | 0.0317 | No | ||
35 | PFN2 | 730040 5700026 | 3328 | 0.450 | 0.0296 | No | ||
36 | DMTF1 | 5910047 1570497 2480100 6620239 | 3568 | 0.370 | 0.0182 | No | ||
37 | TARDBP | 870390 2350093 | 3982 | 0.257 | -0.0032 | No | ||
38 | ZFP36L2 | 510180 | 3995 | 0.253 | -0.0027 | No | ||
39 | FLT1 | 3830167 4920438 | 4046 | 0.244 | -0.0044 | No | ||
40 | LATS2 | 4480593 6020494 | 4072 | 0.239 | -0.0047 | No | ||
41 | POLQ | 1050053 2190102 | 4099 | 0.235 | -0.0051 | No | ||
42 | CDCA7 | 3060097 | 4118 | 0.232 | -0.0050 | No | ||
43 | DHX40 | 360672 | 4185 | 0.221 | -0.0077 | No | ||
44 | ST8SIA2 | 2680082 | 4267 | 0.208 | -0.0112 | No | ||
45 | LUC7L2 | 1850402 6350088 | 4363 | 0.197 | -0.0155 | No | ||
46 | RHOC | 2060242 | 4478 | 0.181 | -0.0209 | No | ||
47 | FOXL2 | 5670537 | 4541 | 0.175 | -0.0235 | No | ||
48 | MMP24 | 5340154 | 4542 | 0.175 | -0.0227 | No | ||
49 | RABEP1 | 4760427 6200463 | 4621 | 0.166 | -0.0263 | No | ||
50 | PCAF | 2230161 2570369 6550451 | 4647 | 0.163 | -0.0269 | No | ||
51 | SYNC1 | 580114 | 4651 | 0.163 | -0.0264 | No | ||
52 | NEO1 | 1990154 | 4656 | 0.162 | -0.0259 | No | ||
53 | NFIB | 460450 | 4710 | 0.157 | -0.0281 | No | ||
54 | ARID4B | 730754 6660026 | 4844 | 0.145 | -0.0347 | No | ||
55 | EDNRB | 4280717 6400435 | 4894 | 0.140 | -0.0367 | No | ||
56 | OLFM3 | 580112 1050072 4070204 | 5078 | 0.127 | -0.0461 | No | ||
57 | ARID4A | 520156 1050707 | 5087 | 0.126 | -0.0460 | No | ||
58 | GABPB2 | 6130450 7050735 | 5132 | 0.123 | -0.0479 | No | ||
59 | UBE2R2 | 1230504 | 5187 | 0.119 | -0.0503 | No | ||
60 | NEUROD1 | 3060619 | 5284 | 0.114 | -0.0550 | No | ||
61 | ESR1 | 4060372 5860193 | 5420 | 0.106 | -0.0619 | No | ||
62 | DPYSL5 | 4900333 | 5484 | 0.102 | -0.0649 | No | ||
63 | RABGAP1 | 5050397 | 5542 | 0.100 | -0.0675 | No | ||
64 | SLITRK3 | 5910041 | 5708 | 0.092 | -0.0761 | No | ||
65 | RGL1 | 1500097 6900450 | 5803 | 0.086 | -0.0809 | No | ||
66 | FNDC3A | 2690097 3290044 | 5805 | 0.086 | -0.0805 | No | ||
67 | ZKSCAN1 | 6380605 | 5916 | 0.082 | -0.0862 | No | ||
68 | PCDHA1 | 940026 540484 | 6143 | 0.073 | -0.0981 | No | ||
69 | RSBN1 | 7000487 | 6157 | 0.073 | -0.0985 | No | ||
70 | MLLT6 | 3870168 | 6377 | 0.065 | -0.1101 | No | ||
71 | PRRX1 | 4120193 4480390 | 6431 | 0.063 | -0.1128 | No | ||
72 | ECT2 | 3830086 | 6951 | 0.049 | -0.1408 | No | ||
73 | PURA | 3870156 | 7018 | 0.047 | -0.1441 | No | ||
74 | ZBTB4 | 6450441 | 7042 | 0.046 | -0.1452 | No | ||
75 | MYT1L | 5670369 6660403 | 7105 | 0.045 | -0.1484 | No | ||
76 | NPAS3 | 630408 4610066 | 7267 | 0.041 | -0.1569 | No | ||
77 | TLOC1 | 4050309 | 7305 | 0.041 | -0.1588 | No | ||
78 | ETV1 | 70735 2940603 5080463 | 7339 | 0.040 | -0.1604 | No | ||
79 | DRD1 | 430025 | 7409 | 0.039 | -0.1640 | No | ||
80 | PHF6 | 3120632 3990041 | 7650 | 0.034 | -0.1769 | No | ||
81 | LASS6 | 5890576 6520138 | 7658 | 0.034 | -0.1771 | No | ||
82 | BRP44L | 1340605 | 7794 | 0.031 | -0.1843 | No | ||
83 | ARHGEF17 | 2060008 | 8124 | 0.025 | -0.2021 | No | ||
84 | PCDHA3 | 3840402 | 8225 | 0.023 | -0.2074 | No | ||
85 | EPAS1 | 5290156 | 8237 | 0.023 | -0.2079 | No | ||
86 | OSBPL5 | 3840537 6040286 | 8242 | 0.023 | -0.2080 | No | ||
87 | BAMBI | 6650463 | 8300 | 0.022 | -0.2110 | No | ||
88 | ANKRD13C | 5270202 | 8436 | 0.020 | -0.2183 | No | ||
89 | ATP2B2 | 3780397 | 8440 | 0.020 | -0.2184 | No | ||
90 | LHX8 | 5700347 | 8571 | 0.017 | -0.2254 | No | ||
91 | RAD23B | 2190671 | 8675 | 0.016 | -0.2309 | No | ||
92 | PCDHA10 | 3830725 | 8973 | 0.011 | -0.2470 | No | ||
93 | ZFPM2 | 460072 | 9001 | 0.010 | -0.2484 | No | ||
94 | TIPARP | 50397 | 9436 | 0.004 | -0.2720 | No | ||
95 | KCNMA1 | 1450402 | 9448 | 0.004 | -0.2726 | No | ||
96 | ZMYND11 | 630181 2570019 4850138 5360040 | 9589 | 0.002 | -0.2802 | No | ||
97 | LHX6 | 2360731 3360397 | 9697 | -0.000 | -0.2860 | No | ||
98 | SLC2A4 | 540441 | 9930 | -0.003 | -0.2986 | No | ||
99 | VSX1 | 4610605 6650112 | 10054 | -0.005 | -0.3053 | No | ||
100 | PCDHA5 | 2970347 | 10288 | -0.009 | -0.3179 | No | ||
101 | CCNJ | 870047 | 10319 | -0.009 | -0.3195 | No | ||
102 | PCDHA12 | 2810215 | 10590 | -0.013 | -0.3341 | No | ||
103 | PRDM8 | 840746 | 10648 | -0.014 | -0.3371 | No | ||
104 | ALX4 | 3870019 | 10659 | -0.014 | -0.3376 | No | ||
105 | TAOK2 | 110575 6380692 | 10719 | -0.015 | -0.3408 | No | ||
106 | ABCA1 | 6290156 | 10877 | -0.018 | -0.3492 | No | ||
107 | ANK2 | 6510546 | 11263 | -0.024 | -0.3701 | No | ||
108 | SSX2IP | 4610176 | 11299 | -0.025 | -0.3719 | No | ||
109 | PAK7 | 3830164 | 11352 | -0.026 | -0.3746 | No | ||
110 | NR4A3 | 2900021 5860095 5910039 | 11360 | -0.026 | -0.3748 | No | ||
111 | E2F5 | 5860575 | 11554 | -0.029 | -0.3852 | No | ||
112 | VLDLR | 870722 3060047 5340452 6550131 | 11555 | -0.029 | -0.3851 | No | ||
113 | CREB5 | 2320368 | 11678 | -0.032 | -0.3916 | No | ||
114 | ZBTB11 | 6520092 | 11830 | -0.035 | -0.3996 | No | ||
115 | NTN4 | 6940398 | 12061 | -0.040 | -0.4120 | No | ||
116 | PCDHA11 | 1510253 | 12203 | -0.043 | -0.4194 | No | ||
117 | HLF | 2370113 | 12240 | -0.044 | -0.4212 | No | ||
118 | MEF2C | 670025 780338 | 12428 | -0.048 | -0.4312 | No | ||
119 | NEUROD6 | 4670731 | 12501 | -0.050 | -0.4349 | No | ||
120 | PCDHA6 | 780333 2370280 | 12619 | -0.054 | -0.4410 | No | ||
121 | PAPOLA | 4200286 4850112 | 12676 | -0.055 | -0.4438 | No | ||
122 | PLXNA1 | 70066 | 12837 | -0.061 | -0.4522 | No | ||
123 | PLAG1 | 1450142 3870139 6520039 | 12927 | -0.064 | -0.4568 | No | ||
124 | ARHGEF10 | 3120593 6900673 | 12974 | -0.065 | -0.4590 | No | ||
125 | OSBPL8 | 50603 | 12991 | -0.066 | -0.4596 | No | ||
126 | WEE1 | 3390070 | 13037 | -0.067 | -0.4617 | No | ||
127 | MINK1 | 5860647 | 13258 | -0.076 | -0.4734 | No | ||
128 | UBE2B | 4780497 | 13329 | -0.080 | -0.4768 | No | ||
129 | RB1CC1 | 510494 7100072 | 13362 | -0.081 | -0.4782 | No | ||
130 | PGBD5 | 1190047 | 13371 | -0.082 | -0.4783 | No | ||
131 | EPHA2 | 5890056 | 13432 | -0.085 | -0.4812 | No | ||
132 | KLF12 | 1660095 4810288 5340546 6520286 | 13492 | -0.087 | -0.4840 | No | ||
133 | MARCH8 | 60397 | 13652 | -0.096 | -0.4922 | No | ||
134 | TRPV6 | 4010717 | 13726 | -0.101 | -0.4958 | No | ||
135 | RAB11FIP1 | 2470333 | 13876 | -0.112 | -0.5034 | No | ||
136 | PARP8 | 4150204 | 13947 | -0.117 | -0.5067 | No | ||
137 | CYP26B1 | 2630142 | 14006 | -0.121 | -0.5093 | No | ||
138 | BRMS1L | 6110609 | 14095 | -0.128 | -0.5135 | No | ||
139 | RPS6KA5 | 2120563 7040546 | 14110 | -0.130 | -0.5137 | No | ||
140 | DDHD1 | 3450241 3940523 6380156 | 14189 | -0.137 | -0.5174 | No | ||
141 | SENP1 | 6100537 | 14216 | -0.140 | -0.5182 | No | ||
142 | FGD5 | 3520438 4060500 | 14278 | -0.146 | -0.5209 | No | ||
143 | MTUS1 | 780348 4920609 | 14359 | -0.155 | -0.5245 | No | ||
144 | RBL1 | 3130372 | 14394 | -0.158 | -0.5257 | No | ||
145 | KLHL18 | 4560075 | 14480 | -0.167 | -0.5296 | No | ||
146 | KPNA2 | 3450114 | 14510 | -0.169 | -0.5304 | No | ||
147 | NR2C2 | 6100097 | 14785 | -0.211 | -0.5444 | No | ||
148 | PLEKHA3 | 5080068 | 14863 | -0.226 | -0.5476 | No | ||
149 | NR4A2 | 60273 | 14939 | -0.245 | -0.5506 | No | ||
150 | ATAD2 | 870242 2260687 | 15260 | -0.328 | -0.5666 | No | ||
151 | RAB6A | 3840463 4780731 | 15308 | -0.341 | -0.5677 | No | ||
152 | TAL1 | 7040239 | 15339 | -0.351 | -0.5678 | No | ||
153 | RAB11A | 5360079 | 15342 | -0.352 | -0.5664 | No | ||
154 | SAR1B | 2510273 | 15384 | -0.364 | -0.5670 | No | ||
155 | CRIM1 | 130491 | 15400 | -0.368 | -0.5662 | No | ||
156 | SNF1LK | 6110403 | 15440 | -0.381 | -0.5667 | No | ||
157 | LEF1 | 2470082 7100288 | 15463 | -0.392 | -0.5662 | No | ||
158 | GNB5 | 4480736 6550722 6770463 | 15485 | -0.402 | -0.5656 | No | ||
159 | ZNF385 | 450176 4810358 | 15598 | -0.448 | -0.5697 | No | ||
160 | MKNK2 | 1240020 5270092 | 15668 | -0.482 | -0.5714 | No | ||
161 | YPEL2 | 5560609 | 15730 | -0.512 | -0.5725 | No | ||
162 | E2F7 | 4200056 | 15843 | -0.563 | -0.5761 | No | ||
163 | PURB | 5360138 | 15929 | -0.615 | -0.5781 | No | ||
164 | CFL2 | 380239 6200368 | 16022 | -0.663 | -0.5802 | Yes | ||
165 | SF4 | 3830341 | 16069 | -0.693 | -0.5797 | Yes | ||
166 | COL23A1 | 2030358 | 16070 | -0.693 | -0.5767 | Yes | ||
167 | RDBP | 6590044 | 16073 | -0.694 | -0.5738 | Yes | ||
168 | OXR1 | 2370039 3190706 | 16099 | -0.710 | -0.5720 | Yes | ||
169 | MNT | 4920575 | 16146 | -0.736 | -0.5713 | Yes | ||
170 | RNF6 | 2640035 | 16152 | -0.739 | -0.5684 | Yes | ||
171 | DNAJA2 | 2630253 6860358 | 16235 | -0.794 | -0.5694 | Yes | ||
172 | ORMDL3 | 1340711 | 16371 | -0.883 | -0.5729 | Yes | ||
173 | MTMR3 | 1050014 4920180 | 16463 | -0.938 | -0.5738 | Yes | ||
174 | SPOP | 450035 | 16478 | -0.950 | -0.5704 | Yes | ||
175 | CRK | 1230162 4780128 | 16534 | -0.989 | -0.5691 | Yes | ||
176 | PLEKHM1 | 1050161 1990750 | 16569 | -1.001 | -0.5666 | Yes | ||
177 | MAPK9 | 2060273 3780209 4070397 | 16570 | -1.002 | -0.5623 | Yes | ||
178 | AEBP2 | 2970603 | 16681 | -1.066 | -0.5636 | Yes | ||
179 | SMAD2 | 4200592 | 16721 | -1.104 | -0.5609 | Yes | ||
180 | MECP2 | 1940450 | 16762 | -1.137 | -0.5582 | Yes | ||
181 | ATXN1 | 5550156 | 16822 | -1.187 | -0.5562 | Yes | ||
182 | FRMD4A | 2190176 | 16892 | -1.242 | -0.5546 | Yes | ||
183 | FEM1C | 60300 6130717 6980164 | 16931 | -1.273 | -0.5511 | Yes | ||
184 | TUSC2 | 1580253 | 17089 | -1.460 | -0.5533 | Yes | ||
185 | PERQ1 | 1340164 | 17172 | -1.554 | -0.5510 | Yes | ||
186 | BCL11A | 6860369 | 17185 | -1.577 | -0.5448 | Yes | ||
187 | MAP3K14 | 5890435 | 17267 | -1.682 | -0.5419 | Yes | ||
188 | WDR37 | 2630519 6840347 | 17300 | -1.721 | -0.5362 | Yes | ||
189 | HRBL | 1850102 3830253 4780176 | 17333 | -1.765 | -0.5302 | Yes | ||
190 | RASSF2 | 2480079 5720546 | 17340 | -1.774 | -0.5228 | Yes | ||
191 | IQWD1 | 160475 | 17370 | -1.819 | -0.5165 | Yes | ||
192 | NFYA | 5860368 | 17556 | -2.131 | -0.5173 | Yes | ||
193 | DUSP2 | 2370184 | 17558 | -2.134 | -0.5081 | Yes | ||
194 | RUNX1 | 3840711 | 17599 | -2.206 | -0.5007 | Yes | ||
195 | HN1 | 3360156 | 17603 | -2.212 | -0.4912 | Yes | ||
196 | MKRN1 | 1410097 | 17609 | -2.221 | -0.4819 | Yes | ||
197 | ASF1B | 6590706 | 17648 | -2.327 | -0.4738 | Yes | ||
198 | HIC2 | 4010433 | 17664 | -2.356 | -0.4644 | Yes | ||
199 | TMEM16F | 5860008 | 17783 | -2.591 | -0.4595 | Yes | ||
200 | ZDHHC9 | 3940204 | 17851 | -2.740 | -0.4513 | Yes | ||
201 | RRAGD | 670075 | 17898 | -2.843 | -0.4414 | Yes | ||
202 | ULK1 | 6100315 | 17921 | -2.898 | -0.4300 | Yes | ||
203 | MAP3K11 | 7000039 | 17928 | -2.933 | -0.4176 | Yes | ||
204 | FOXJ2 | 2450441 | 18029 | -3.166 | -0.4093 | Yes | ||
205 | TLE4 | 1450064 1500519 | 18134 | -3.567 | -0.3995 | Yes | ||
206 | BCL2L11 | 780044 4200601 | 18141 | -3.609 | -0.3841 | Yes | ||
207 | IRF2 | 5390044 | 18151 | -3.645 | -0.3688 | Yes | ||
208 | CREBL1 | 1340546 | 18186 | -3.784 | -0.3542 | Yes | ||
209 | TOB2 | 1240465 | 18216 | -3.905 | -0.3388 | Yes | ||
210 | IHPK1 | 1340053 | 18235 | -4.035 | -0.3222 | Yes | ||
211 | ZFYVE26 | 6860152 | 18236 | -4.044 | -0.3046 | Yes | ||
212 | WDR45 | 1660538 | 18250 | -4.116 | -0.2875 | Yes | ||
213 | KLF13 | 4670563 | 18309 | -4.420 | -0.2714 | Yes | ||
214 | MCL1 | 1660672 | 18331 | -4.573 | -0.2527 | Yes | ||
215 | BCL6 | 940100 | 18397 | -5.006 | -0.2345 | Yes | ||
216 | PPP6C | 2450670 | 18401 | -5.045 | -0.2127 | Yes | ||
217 | PLAGL2 | 1770148 | 18469 | -5.739 | -0.1914 | Yes | ||
218 | MAML1 | 2760008 | 18494 | -5.971 | -0.1668 | Yes | ||
219 | ARHGEF18 | 2120279 | 18535 | -6.700 | -0.1398 | Yes | ||
220 | PHF2 | 4060300 | 18540 | -6.759 | -0.1107 | Yes | ||
221 | CCND2 | 5340167 | 18589 | -8.378 | -0.0769 | Yes | ||
222 | TOX | 3440053 | 18599 | -8.651 | -0.0398 | Yes | ||
223 | BTG1 | 4200735 6040131 6200133 | 18614 | -9.359 | 0.0001 | Yes |