Dataset | Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos |
Phenotype | phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos |
Upregulated in class | normalThy |
GeneSet | AAGCAAT,MIR-137 |
Enrichment Score (ES) | -0.5672238 |
Normalized Enrichment Score (NES) | -1.5088432 |
Nominal p-value | 0.0 |
FDR q-value | 0.12581247 |
FWER p-Value | 0.81 |
PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|---|
1 | MAPKAPK2 | 2850500 | 616 | 2.672 | -0.0079 | No | ||
2 | DDX3X | 2190020 | 681 | 2.564 | 0.0131 | No | ||
3 | CUL3 | 1850520 | 1147 | 1.860 | 0.0057 | No | ||
4 | SLC6A6 | 6100300 | 1518 | 1.515 | 0.0001 | No | ||
5 | PPP5C | 3130047 | 1548 | 1.489 | 0.0128 | No | ||
6 | XPO4 | 3840551 | 1640 | 1.403 | 0.0212 | No | ||
7 | CHORDC1 | 6650577 | 1693 | 1.359 | 0.0314 | No | ||
8 | MTPN | 3940167 | 2405 | 0.876 | 0.0012 | No | ||
9 | MIB1 | 3800537 | 2547 | 0.789 | 0.0011 | No | ||
10 | CDC42 | 1240168 3440278 4480519 5290162 | 2599 | 0.760 | 0.0056 | No | ||
11 | CLPX | 6220156 | 2681 | 0.719 | 0.0081 | No | ||
12 | CRSP2 | 1940059 | 2885 | 0.625 | 0.0031 | No | ||
13 | SLC25A5 | 1980672 | 3209 | 0.496 | -0.0097 | No | ||
14 | RPS13 | 1570364 | 3334 | 0.448 | -0.0121 | No | ||
15 | TRIM33 | 580619 2230280 3990433 6200747 | 3348 | 0.446 | -0.0086 | No | ||
16 | ZC3H6 | 130711 | 3481 | 0.400 | -0.0119 | No | ||
17 | HNRPDL | 1050102 1090181 5360471 | 3587 | 0.362 | -0.0141 | No | ||
18 | CUL4A | 1170088 2320008 2470278 | 3616 | 0.349 | -0.0123 | No | ||
19 | RUNX2 | 1400193 4230215 | 3628 | 0.345 | -0.0096 | No | ||
20 | STC1 | 360161 | 3684 | 0.328 | -0.0095 | No | ||
21 | RANBP2 | 4280338 | 3721 | 0.318 | -0.0084 | No | ||
22 | TARDBP | 870390 2350093 | 3982 | 0.257 | -0.0200 | No | ||
23 | MORC4 | 1740040 | 4015 | 0.250 | -0.0194 | No | ||
24 | RHOBTB1 | 1410010 | 4108 | 0.234 | -0.0221 | No | ||
25 | AMD1 | 6290128 | 4209 | 0.217 | -0.0255 | No | ||
26 | NFASC | 1940619 2470156 4590168 6840524 | 4397 | 0.192 | -0.0338 | No | ||
27 | ASPH | 360722 1940039 2100066 2340121 2650113 2810064 2970008 3140040 3800750 4210014 4280133 4590035 4760433 6370671 6940338 | 4595 | 0.169 | -0.0428 | No | ||
28 | SYNC1 | 580114 | 4651 | 0.163 | -0.0443 | No | ||
29 | KLHL10 | 780139 | 4822 | 0.147 | -0.0521 | No | ||
30 | ARID4B | 730754 6660026 | 4844 | 0.145 | -0.0518 | No | ||
31 | WIF1 | 7100184 | 4850 | 0.145 | -0.0507 | No | ||
32 | SON | 3120148 5860239 7040403 | 4954 | 0.136 | -0.0550 | No | ||
33 | QKI | 5220093 6130044 | 5026 | 0.130 | -0.0576 | No | ||
34 | PDLIM3 | 1410095 | 5203 | 0.118 | -0.0660 | No | ||
35 | NEUROD1 | 3060619 | 5284 | 0.114 | -0.0692 | No | ||
36 | EIF4A2 | 1170494 1740711 2850504 | 5311 | 0.112 | -0.0696 | No | ||
37 | RAP2C | 1690132 | 5324 | 0.111 | -0.0692 | No | ||
38 | PLCB1 | 2570050 7100102 | 5457 | 0.104 | -0.0753 | No | ||
39 | MGAT5B | 380131 2570364 | 5561 | 0.099 | -0.0799 | No | ||
40 | FNDC3A | 2690097 3290044 | 5805 | 0.086 | -0.0923 | No | ||
41 | PPARGC1A | 4670040 | 5917 | 0.082 | -0.0975 | No | ||
42 | DUSP8 | 6650039 | 6111 | 0.074 | -0.1072 | No | ||
43 | BSN | 5270347 | 6137 | 0.073 | -0.1079 | No | ||
44 | RSBN1 | 7000487 | 6157 | 0.073 | -0.1082 | No | ||
45 | BMPR2 | 5340066 6960328 | 6413 | 0.064 | -0.1214 | No | ||
46 | PICALM | 1940280 | 6457 | 0.062 | -0.1232 | No | ||
47 | PTGFRN | 4120524 | 6582 | 0.058 | -0.1293 | No | ||
48 | FBXL7 | 6620711 | 6653 | 0.056 | -0.1326 | No | ||
49 | UBE2H | 1980142 2970079 | 6987 | 0.048 | -0.1502 | No | ||
50 | FLRT2 | 4200035 | 7112 | 0.045 | -0.1564 | No | ||
51 | AP1G1 | 2360671 | 7399 | 0.039 | -0.1716 | No | ||
52 | ESRRG | 4010181 | 7424 | 0.038 | -0.1725 | No | ||
53 | THBS4 | 3710348 | 7526 | 0.036 | -0.1776 | No | ||
54 | PDCD6 | 4760239 | 7713 | 0.033 | -0.1874 | No | ||
55 | RIMS4 | 6110500 | 7771 | 0.032 | -0.1902 | No | ||
56 | RNF128 | 1230300 5670273 | 7805 | 0.031 | -0.1916 | No | ||
57 | DIO2 | 380504 540403 | 8109 | 0.025 | -0.2078 | No | ||
58 | ZCCHC5 | 2650021 | 8370 | 0.021 | -0.2217 | No | ||
59 | RCN1 | 2480041 | 8399 | 0.020 | -0.2230 | No | ||
60 | DCDC2 | 7000338 | 8430 | 0.020 | -0.2244 | No | ||
61 | SLC17A6 | 4210576 | 8476 | 0.019 | -0.2267 | No | ||
62 | GRIN2A | 6550538 | 8547 | 0.018 | -0.2303 | No | ||
63 | ST18 | 5720537 | 8661 | 0.016 | -0.2363 | No | ||
64 | SHANK2 | 1500452 | 8684 | 0.016 | -0.2373 | No | ||
65 | GPR88 | 2450435 | 8690 | 0.016 | -0.2375 | No | ||
66 | MMP16 | 2680139 | 8729 | 0.015 | -0.2394 | No | ||
67 | NR3C2 | 2480324 6400093 | 8911 | 0.012 | -0.2491 | No | ||
68 | SLC7A9 | 5420735 5700450 | 8934 | 0.011 | -0.2501 | No | ||
69 | PTPN2 | 130315 | 9053 | 0.009 | -0.2564 | No | ||
70 | LBX1 | 1300164 4060204 | 9302 | 0.006 | -0.2698 | No | ||
71 | CBLN2 | 4760132 | 9347 | 0.005 | -0.2721 | No | ||
72 | DMRT2 | 2630068 | 9452 | 0.004 | -0.2777 | No | ||
73 | RFX4 | 3710100 5340215 | 9570 | 0.002 | -0.2841 | No | ||
74 | ZMYND11 | 630181 2570019 4850138 5360040 | 9589 | 0.002 | -0.2850 | No | ||
75 | SOX11 | 610279 | 9618 | 0.001 | -0.2865 | No | ||
76 | CHST9 | 4560092 | 10090 | -0.006 | -0.3120 | No | ||
77 | DPYS | 3130670 | 10476 | -0.011 | -0.3327 | No | ||
78 | MAB21L2 | 1770605 | 10533 | -0.012 | -0.3356 | No | ||
79 | CADPS | 2320181 | 10567 | -0.013 | -0.3373 | No | ||
80 | CACNA1G | 3060161 4810706 5550722 | 10723 | -0.015 | -0.3455 | No | ||
81 | TSSK3 | 1740673 | 10822 | -0.017 | -0.3507 | No | ||
82 | MUM1L1 | 4010411 | 10878 | -0.018 | -0.3535 | No | ||
83 | EPHA7 | 1190288 4010278 | 11012 | -0.020 | -0.3605 | No | ||
84 | RIMS3 | 3890563 | 11473 | -0.028 | -0.3851 | No | ||
85 | MITF | 380056 | 11505 | -0.028 | -0.3865 | No | ||
86 | ACP1 | 1990435 | 11842 | -0.035 | -0.4044 | No | ||
87 | RBMS3 | 6110722 | 12104 | -0.041 | -0.4182 | No | ||
88 | FLRT3 | 70685 2760497 6040519 | 12148 | -0.042 | -0.4201 | No | ||
89 | GREM1 | 3940180 | 12229 | -0.044 | -0.4240 | No | ||
90 | HLF | 2370113 | 12240 | -0.044 | -0.4241 | No | ||
91 | ATOH8 | 4540204 | 12385 | -0.047 | -0.4315 | No | ||
92 | PLEC1 | 6520292 50500 380075 1570088 2510692 2630497 2680017 2900746 4560497 4850376 6290398 7040471 | 12491 | -0.050 | -0.4367 | No | ||
93 | SYT1 | 840364 | 12644 | -0.055 | -0.4444 | No | ||
94 | KCNA2 | 5080403 | 12709 | -0.056 | -0.4473 | No | ||
95 | PRDM1 | 3170347 3520301 | 12786 | -0.059 | -0.4509 | No | ||
96 | ABHD6 | 630717 | 13004 | -0.066 | -0.4620 | No | ||
97 | DR1 | 5860750 | 13020 | -0.067 | -0.4622 | No | ||
98 | RORB | 6400035 | 13067 | -0.068 | -0.4640 | No | ||
99 | ERBB4 | 4610400 4810017 | 13448 | -0.085 | -0.4838 | No | ||
100 | KLF12 | 1660095 4810288 5340546 6520286 | 13492 | -0.087 | -0.4852 | No | ||
101 | ARHGEF7 | 1690441 | 13544 | -0.090 | -0.4872 | No | ||
102 | SLC24A3 | 5080707 | 13619 | -0.094 | -0.4903 | No | ||
103 | RBM12 | 4570239 6040411 6660129 | 13775 | -0.105 | -0.4977 | No | ||
104 | EPHA4 | 460750 | 14117 | -0.130 | -0.5149 | No | ||
105 | AKAP2 | 5550347 | 14122 | -0.131 | -0.5139 | No | ||
106 | STX16 | 70315 | 14134 | -0.132 | -0.5132 | No | ||
107 | SGCD | 2940685 5080753 | 14301 | -0.149 | -0.5208 | No | ||
108 | SNRK | 630021 2030731 6350017 | 14407 | -0.159 | -0.5249 | No | ||
109 | ST3GAL3 | 2810601 | 14625 | -0.184 | -0.5349 | No | ||
110 | THRAP1 | 2470121 | 15052 | -0.267 | -0.5554 | No | ||
111 | WNK4 | 1240682 | 15122 | -0.283 | -0.5565 | No | ||
112 | SH3BP5 | 7100408 | 15208 | -0.312 | -0.5581 | No | ||
113 | CREBBP | 5690035 7040050 | 15330 | -0.349 | -0.5613 | No | ||
114 | SNF1LK | 6110403 | 15440 | -0.381 | -0.5636 | Yes | ||
115 | FURIN | 4120168 | 15450 | -0.385 | -0.5604 | Yes | ||
116 | OGT | 2360131 4610333 | 15489 | -0.403 | -0.5586 | Yes | ||
117 | ZNF385 | 450176 4810358 | 15598 | -0.448 | -0.5602 | Yes | ||
118 | RNF138 | 110142 3870129 6020441 6400193 | 15599 | -0.449 | -0.5559 | Yes | ||
119 | CTDSPL | 4670546 | 15704 | -0.499 | -0.5568 | Yes | ||
120 | PDE4A | 1190619 1340129 5720100 6370035 | 15727 | -0.511 | -0.5531 | Yes | ||
121 | PPP3CB | 6020156 | 15807 | -0.545 | -0.5522 | Yes | ||
122 | SGPL1 | 4480059 | 15839 | -0.561 | -0.5485 | Yes | ||
123 | OXR1 | 2370039 3190706 | 16099 | -0.710 | -0.5557 | Yes | ||
124 | PPARBP | 4280131 5690022 5860050 | 16200 | -0.771 | -0.5538 | Yes | ||
125 | ZDHHC5 | 1690711 | 16303 | -0.843 | -0.5513 | Yes | ||
126 | CSDA | 2470092 3060053 4780056 | 16492 | -0.958 | -0.5523 | Yes | ||
127 | SPHK2 | 2030487 4120670 4850114 | 16532 | -0.987 | -0.5450 | Yes | ||
128 | ESRRA | 6550242 | 16633 | -1.031 | -0.5406 | Yes | ||
129 | SFRS5 | 3450176 6350008 | 16788 | -1.161 | -0.5379 | Yes | ||
130 | RAB21 | 5570070 | 16860 | -1.212 | -0.5301 | Yes | ||
131 | WSB1 | 870563 | 17148 | -1.535 | -0.5310 | Yes | ||
132 | FMNL2 | 4060438 | 17275 | -1.692 | -0.5217 | Yes | ||
133 | NAB2 | 1570014 | 17307 | -1.728 | -0.5069 | Yes | ||
134 | CTDSP2 | 5340315 5690133 | 17338 | -1.768 | -0.4917 | Yes | ||
135 | INPP5A | 5910195 | 17605 | -2.216 | -0.4849 | Yes | ||
136 | DEXI | 6220358 6550685 | 17681 | -2.383 | -0.4663 | Yes | ||
137 | CCNG2 | 3190095 | 17836 | -2.706 | -0.4488 | Yes | ||
138 | RAB35 | 630056 | 17868 | -2.774 | -0.4240 | Yes | ||
139 | TLE4 | 1450064 1500519 | 18134 | -3.567 | -0.4043 | Yes | ||
140 | BACH2 | 6760131 | 18172 | -3.712 | -0.3709 | Yes | ||
141 | ATP1B1 | 3130594 | 18279 | -4.259 | -0.3360 | Yes | ||
142 | DYRK1A | 3190181 | 18295 | -4.333 | -0.2955 | Yes | ||
143 | DNAJB1 | 1090041 | 18371 | -4.807 | -0.2537 | Yes | ||
144 | SRPK1 | 450110 | 18396 | -5.003 | -0.2073 | Yes | ||
145 | SATB1 | 5670154 | 18410 | -5.157 | -0.1588 | Yes | ||
146 | PLAGL2 | 1770148 | 18469 | -5.739 | -0.1072 | Yes | ||
147 | EGR2 | 3800403 | 18475 | -5.788 | -0.0522 | Yes | ||
148 | CTLA4 | 6590537 | 18511 | -6.266 | 0.0057 | Yes |